G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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APD668
CAS:832714-46-2
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for …
Formula:
C21H24FN5O5S
Purity:
99.45% - 99.97%
Color and Shape:
Solid
Molecular weight:
477.51
Ref: TM-T2088
| 1mg | 49.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 639.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Loxiglumide
CAS:107097-80-3
Loxiglumide (CR-1505) is an antagonist of cholecystokinin (CCK-1) receptor.
Formula:
C21H30Cl2N2O5
Purity:
98% - 99.81%
Color and Shape:
Solid
Molecular weight:
461.38
Ref: TM-T2312
| 10mg | 40.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 196.00 € | ||
| 200mg | 337.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Opaganib
CAS:915385-81-8
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
Formula:
C23H25ClN2O
Purity:
98.86% - 99.71%
Color and Shape:
Solid
Molecular weight:
380.91
Ref: TM-T6750
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 236.00 € | ||
| 50mg | 408.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Bremelanotide Acetate
CAS:1607799-13-2
Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) .
Formula:
C52H72N14O12
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
1085.22
Ref: TM-T7608
| 10mg | 50.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 134.00 € | ||
| 100mg | 193.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Nefazodone hydrochloride
CAS:82752-99-6
Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, …
Formula:
C25H33Cl2N5O2
Purity:
99% - 99.86%
Color and Shape:
White Solid
Molecular weight:
506.47
Ref: TM-T3275
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 320.00 € | ||
| 200mg | 465.00 € | ||
| 500mg | 763.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Mizagliflozin
CAS:666843-10-3
Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM …
Formula:
C28H44N4O8
Purity:
98.32% - 98.66%
Color and Shape:
Solid
Molecular weight:
564.67
Ref: TM-T16083
| 1mg | 80.00 € | ||
| 2mg | 103.00 € | ||
| 5mg | 161.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 534.00 € | ||
| 50mg | 764.00 € | ||
| 100mg | 1,049.00 € | ||
| 1mL*10mM (DMSO) | 211.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
![Sar-[D-Phe8]-des-Arg9-Bradykinin acetate](https://static.cymitquimica.com/products/TM/thumb/TP1917L1.jpg)
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM …
Formula:
C49H70N12O13
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
1035.15
Ref: TM-TP1917L1
| 1mg | 170.00 € | ||
| 5mg | 382.00 € | ||
| 10mg | 566.00 € | ||
| 25mg | 841.00 € | ||
| 50mg | 1,081.00 € | ||
| 100mg | 1,521.00 € | ||
| 200mg | 2,061.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Dapiprazole Hydrochloride
CAS:72822-13-0
Dapiprazole Hydrochloride (Glamidolo Hydrochloride) is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors.
Formula:
C19H28ClN5
Purity:
100% - 99.86%
Color and Shape:
Solid
Molecular weight:
361.92
Ref: TM-T3996
| 10mg | 51.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 133.00 € | ||
| 100mg | 185.00 € | ||
| 200mg | 279.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ursodeoxycholic acid sodium
CAS:2898-95-5
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and …
Formula:
C24H40NaO4
Purity:
98% - 98.55%
Color and Shape:
Solid
Molecular weight:
415.56
Ref: TM-T29078
| 50mg | 36.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 111.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CYM5442
CAS:1094042-01-9
CYM5442 is an S1P agonist, targeting to Sphingosine.
Formula:
C23H27N3O4
Purity:
96.65% - 97.57%
Color and Shape:
Solid
Molecular weight:
409.48
Ref: TM-T2026
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 613.00 € | ||
| 500mg | 1,273.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
SBI-553
CAS:1849603-72-0
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
Formula:
C26H31FN4O2
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
450.55
Ref: TM-T16860
| 5mg | 94.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 554.00 € | ||
| 100mg | 891.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Voacamine
CAS:3371-85-5
Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.
Formula:
C43H52N4O5
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
704.9
Ref: TM-T2S0271
| 1mg | 124.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 441.00 € | ||
| 25mg | 705.00 € | ||
| 50mg | 932.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Preladenant
CAS:377727-87-2
Preladenant (SCH-420814) is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) …
Formula:
C25H29N9O3
Purity:
97.32% - 98.18%
Color and Shape:
Solid
Molecular weight:
503.56
Ref: TM-T4290
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 515.00 € | ||
| 500mg | 1,106.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Carbetocin acetate
CAS:1631754-28-3
Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving …
Formula:
C47H73N11O14S
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
1048.22
Ref: TM-T7601L
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 430.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Dasotraline hydrochloride
CAS:675126-08-6
Dasotraline hydrochloride, a dopamine, norepinephrine, and serotonin reuptake inhibitor with IC50s: 4, 6, 11 nM.
Formula:
C16H16Cl3N
Purity:
98.92% - 99.6%
Color and Shape:
Solid
Molecular weight:
328.66
Ref: TM-T3526
| 5mg | 48.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 143.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
![[Sar9] Substance P acetate(77128-75-7 free base)](https://static.cymitquimica.com/products/TM/thumb/TP1862L.jpg)
[Sar9] Substance P acetate(77128-75-7 free base)
[Sar9]-Substance P acetate, an NK-1 receptor agonist, mimics SP's effect on progesterone metabolism.
Formula:
C66H104N18O15S
Purity:
96.67%
Color and Shape:
Solid
Molecular weight:
1421.71
Ref: TM-TP1862L
| 1mg | 89.00 € | ||
| 5mg | 173.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 468.00 € | ||
| 50mg | 681.00 € | ||
| 100mg | 937.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ibrolipim
CAS:133208-93-2
Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via …
Formula:
C19H20BrN2O4P
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
451.25
Ref: TM-T7832
| 5mg | 51.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 246.00 € | ||
| 200mg | 370.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Alizapride hydrochloride
CAS:59338-87-3
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea …
Formula:
C16H21N5O2·HCl
Purity:
99.35% - 99.48%
Color and Shape:
Coa
Molecular weight:
351.83
Ref: TM-T2574
| 25mg | 52.00 € | ||
| 50mg | 76.00 € | ||
| 100mg | 109.00 € | ||
| 200mg | 162.00 € | ||
| 500mg | 263.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
7-Methoxyrosmanol
CAS:113085-62-4
7-Methoxyrosmanol (7-O-Methylrosmanol) can suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and …
Formula:
C21H28O5
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
360.44
Ref: TM-TN1334
| 1mg | 134.00 € | ||
| 5mg | 325.00 € | ||
| 10mg | 487.00 € | ||
| 25mg | 774.00 € | ||
| 50mg | 1,040.00 € | ||
| 1mL*10mM (DMSO) | 366.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Amitriptyline
CAS:50-48-6
Amitriptyline: a tricyclic antidepressant used for depression and neuropathic pain.
Formula:
C20H23N
Purity:
98.24% - 99.64%
Color and Shape:
Crystals Solid
Molecular weight:
277.4
Ref: TM-T22240
| 10mg | 46.00 € | ||
| 25mg | 67.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 129.00 € | ||
| 200mg | 185.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
