G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Ritanserin
CAS:87051-43-2
Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective …
Formula:
C27H25F2N3OS
Purity:
99.45% - 99.89%
Color and Shape:
Solid
Molecular weight:
477.57
Ref: TM-T16759
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 403.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Trimethobenzamide hydrochloride
CAS:554-92-7
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic …
Formula:
C21H29ClN2O5
Purity:
100%
Color and Shape:
Solid
Molecular weight:
424.92
Ref: TM-T5009
| 1g | 139.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 88.00 € | ||
| 200mg | 110.00 € | ||
| 500mg | 162.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
CRF (6-33) acetate(120066-38-8 free base)
CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.
Formula:
C143H235N41O45S
Purity:
97.12%
Color and Shape:
Solid
Molecular weight:
3280.76
Ref: TM-TP2047L
| 1mg | 206.00 € | ||
| 5mg | 465.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 952.00 € | ||
| 50mg | 1,284.00 € | ||
| 100mg | 1,727.00 € | ||
| 200mg | 2,337.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ML417
CAS:1386162-69-1
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
Formula:
C22H25N3O3
Purity:
98.81% - 99.42%
Color and Shape:
Solid
Molecular weight:
379.45
Ref: TM-T8423
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 495.00 € | ||
| 200mg | 419.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Nociceptin (1-13) amide TFA
Nociceptin (1-13), amide: ORL1 receptor agonist, pEC50 7.9 (mouse vas deferens), Ki 0.75 nM (rat …
Formula:
C63H101F3N22O17
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1495.61
Ref: TM-TP1793L
| 1mg | 130.00 € | ||
| 5mg | 284.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 701.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,332.00 € | ||
| 200mg | 1,044.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MIPS521
CAS:1146188-19-3
MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R.
Formula:
C19H10ClF6NOS
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
449.8
Ref: TM-T9330
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
b-Casomorphin (1-3) Acetate
b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.
Formula:
C25H31N3O7
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
485.53
Ref: TM-T21660L
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 332.00 € | ||
| 200mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Methylene Blue trihydrate
CAS:7220-79-3
Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in …
Formula:
C16H24ClN3O3S
Purity:
95.42% - 98.91%
Color and Shape:
Dark Green Solid
Molecular weight:
373.9
Ref: TM-T0006
| 10g | 49.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Phentolamine
CAS:50-60-2
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
Formula:
C17H19N3O
Purity:
100% - 99.86%
Color and Shape:
Crystals Solid
Molecular weight:
281.35
Ref: TM-T8348
| 5mg | 53.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 177.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
UNBS5162
CAS:956590-23-1
UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
Formula:
C17H18N4O3
Purity:
98.37% - 99.97%
Color and Shape:
Solid
Molecular weight:
326.35
Ref: TM-T2477
| 1mg | 39.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 336.00 € | ||
| 100mg | 534.00 € | ||
| 200mg | 778.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SB 204741
CAS:152239-46-8
SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.
Formula:
C14H14N4OS
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
286.35
Ref: TM-T23312
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 655.00 € | ||
| 200mg | 546.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
![1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID](https://static.cymitquimica.com/products/TM/thumb/T8913.jpg)
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
CAS:260555-42-8
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.
Formula:
C13H13NO5
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
263.25
Ref: TM-T8913
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 164.00 € | ||
| 200mg | 238.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GW9508
CAS:885101-89-3
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in …
Formula:
C22H21NO3
Purity:
97.89% - 99.19%
Color and Shape:
Solid
Molecular weight:
347.41
Ref: TM-T1781
| 10mg | 34.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 136.00 € | ||
| 200mg | 195.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ACTH 1-14 acetate(25696-21-3 free base)
ACTH 1-14 acetate regulates cortisol and androgen, is part of the hypothalamic-pituitary-adrenal stress response.
Formula:
C79H113N21O22S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1740.96
Ref: TM-TP1238L
| 1mg | 50.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 540.00 € | ||
| 200mg | 713.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Fuscoside
CAS:131631-89-5
Fuscoside (OPC-21268) is a non-peptide arginine vasopressin (AVP) receptor VI antagonist with an IC50 value …
Formula:
C26H31N3O4
Purity:
97.98% - 99.66%
Color and Shape:
Solid
Molecular weight:
449.54
Ref: TM-T4355
| 2mg | 56.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 411.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GRK5-IN-2
CAS:1642839-27-7
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.
Formula:
C20H20N4O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T9609
| 2mg | 35.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
(±)-Cannabichromene
CAS:20675-51-8
(±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the TRPA1.
Formula:
C21H30O2
Purity:
96.89% - 99.1%
Color and Shape:
Solid
Molecular weight:
314.46
Ref: TM-TN3575
| 1mg | 167.00 € | ||
| 5mg | 402.00 € | ||
| 10mg | 586.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,233.00 € | ||
| 100mg | 1,662.00 € | ||
| 500mg | 3,333.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Icatibant Acetate
CAS:138614-30-9
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of …
Formula:
C61H93N19O15S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1364.57
Ref: TM-T22344
| 1mg | 69.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 493.00 € | ||
| 50mg | 702.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 373.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
AM281
CAS:202463-68-1
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and …
Formula:
C21H19Cl2IN4O2
Purity:
100% - 99.2%
Color and Shape:
White To Off-White Solid
Molecular weight:
557.21
Ref: TM-T2264
| 1mg | 84.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 271.00 € | ||
| 25mg | 546.00 € | ||
| 50mg | 782.00 € | ||
| 100mg | 1,079.00 € | ||
| 200mg | 849.00 € | ||
| 500mg | 2,135.00 € | ||
| 1mL*10mM (DMSO) | 242.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Emedastine
CAS:87233-61-2
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.
Formula:
C17H26N4O
Purity:
97.1% - 97.1%
Color and Shape:
Oil
Molecular weight:
302.41
Ref: TM-T3979
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 409.00 € | ||
| 500mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
