G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Siramesine
CAS:147817-50-3
Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to …
Formula:
C30H31FN2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
454.58
Ref: TM-T4620
| 5mg | 193.00 € | ||
| 10mg | 293.00 € | ||
| 25mg | 447.00 € | ||
| 50mg | 688.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
![[Sar9,Met(O2)11]-Substance P acetate](https://static.cymitquimica.com/products/TM/thumb/TP1369L.jpg)
[Sar9,Met(O2)11]-Substance P acetate
[Sar9,Met(O2)11]-Substance P acetate is an NK1 agonist, raising MAP and HR equally to septide but …
Formula:
C67H106N18O17S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1467.75
Ref: TM-TP1369L
| 1mg | 91.00 € | ||
| 5mg | 349.00 € | ||
| 10mg | 518.00 € | ||
| 25mg | 834.00 € | ||
| 50mg | 1,129.00 € | ||
| 100mg | 1,546.00 € | ||
| 500mg | 3,039.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
BD 1008 dihydrobromide
CAS:138356-09-9
BD 1008 dihydrobromide: selective σ1 receptor antagonist (Ki=2 nM), high σ1 and moderate σ2 affinity.
Formula:
C15H24Br2Cl2N2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
463.08
Ref: TM-T21788
| 1mg | 64.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 200.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
AZD1981
CAS:802904-66-1
AZD1981: selective CRTh2 antagonist, IC50 4 nM, 1000x specificity over 340+ enzymes/receptors, tested in asthma …
Formula:
C19H17ClN2O3S
Purity:
98.59% - 99.54%
Color and Shape:
Solid
Molecular weight:
388.87
Ref: TM-T6399
| 10mg | 50.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 265.00 € | ||
| 200mg | 386.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Almotriptan
CAS:154323-57-6
Almotriptan (LAS 31416), a triptan and 5-HT1B/1D agonist, treats migraines by constricting cranial vessels and …
Formula:
C17H25N3O2S
Purity:
99.85%
Color and Shape:
Light Yellow Or White Power
Molecular weight:
335.46
Ref: TM-T21231
| 5mg | 43.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 160.00 € | ||
| 100mg | 228.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
APD597
CAS:897732-93-3
APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.
Formula:
C21H29N5O6S
Purity:
99.63% - 99.87%
Color and Shape:
Solid
Molecular weight:
479.55
Ref: TM-T3176
| 5mg | 70.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 349.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ropinirole
CAS:91374-21-9
Ropinirole, D2-like agonist, no D1 affinity, Ki 29 nM for D2, treats Parkinson's.
Formula:
C16H24N2O
Color and Shape:
Liquid
Molecular weight:
260.38
Ref: TM-T60418
| 1mg | 279.00 € | ||
| 5mg | 687.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,386.00 € | ||
| 50mg | 1,805.00 € | ||
| 100mg | 2,279.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Etilevodopa hydrochloride
CAS:39740-30-2
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric …
Formula:
C11H16ClNO4
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
261.7
Ref: TM-T24047
| 10mg | 51.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 155.00 € | ||
| 100mg | 241.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
FAUC 346
CAS:474432-65-0
FAUC 346 is a highly selective D3 partial agonist with EC50 of 1.5 nM.
Formula:
C24H29N3O2S
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
423.57
Ref: TM-T9081
| 1mg | 37.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 533.00 € | ||
| 200mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
HTMT dimaleate
CAS:195867-54-0
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist.
Formula:
C27H33F3N4O9
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
614.57
Ref: TM-T22842
| 1mg | 36.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 214.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
LGnRH-III, lamprey acetate(147859-97-0 free base)
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the …
Formula:
C61H78N18O16
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
1319.38
Ref: TM-TP1700L
| 1mg | 130.00 € | ||
| 5mg | 284.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 701.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,332.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Neuropeptide S (Mouse) acetate
Neuropeptide S (Mouse) acetate is a bioactive peptide.
Formula:
C95H160N34O29
Purity:
98.25%
Color and Shape:
Solid
Molecular weight:
2242.5
Ref: TM-TP1981L
| 1mg | 143.00 € | ||
| 5mg | 312.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 739.00 € | ||
| 50mg | 1,049.00 € | ||
| 100mg | 1,411.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Mozavaptan
CAS:137975-06-5
Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with …
Formula:
C27H29N3O2
Purity:
98.98% - 99.12%
Color and Shape:
Solid
Molecular weight:
427.54
Ref: TM-T6288
| 10mg | 50.00 € | ||
| 25mg | 72.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 148.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Endomorphin 2
CAS:141801-26-5
EM-2 reduces sEPSC frequency/amplitude in lamina IX motoneurons; CTOP reverses this. EM-2-IR affects limb muscles …
Formula:
C32H37N5O5
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
571.67
Ref: TM-T7218
| 1mg | 48.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 466.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Pardoprunox hydrochloride
CAS:269718-83-4
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and …
Formula:
C12H16ClN3O2
Purity:
98.73% - 99.13%
Color and Shape:
Solid
Molecular weight:
269.73
Ref: TM-T3431
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Rizatriptan benzoate
CAS:145202-66-0
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT …
Formula:
C22H25N5O2
Purity:
99% - 99.72%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
391.47
Ref: TM-T1512
| 10mg | 51.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 186.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Istradefylline
CAS:155270-99-8
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is …
Formula:
C20H24N4O4
Purity:
98.18% - 98.57%
Color and Shape:
Solid
Molecular weight:
384.43
Ref: TM-T6552
| 5mg | 41.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 152.00 € | ||
| 200mg | 222.00 € | ||
| 500mg | 370.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CYN 154806 TFA
CAS:2828432-46-6
CYN 154806 TFA: cyclic octapeptide, selective somatostatin sst2 antagonist; pIC50: sst2 - 8.58, sst1 - …
Formula:
C58H69F3N12O16S2
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
1311.36
Ref: TM-TP1346
| 1mg | 145.00 € | ||
| 5mg | 454.00 € | ||
| 10mg | 654.00 € | ||
| 25mg | 1,025.00 € | ||
| 50mg | 1,404.00 € | ||
| 100mg | 1,859.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
AZD4635
CAS:1321514-06-0
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
Formula:
C15H11ClFN5
Purity:
99.15% - 99.61%
Color and Shape:
Solid
Molecular weight:
315.73
Ref: TM-T4265
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 451.00 € | ||
| 500mg | 985.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
GPR120 Agonist 2
CAS:1234844-11-1
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist.
Formula:
C22H25ClO4
Purity:
98.64% - 99.52%
Color and Shape:
Solid
Molecular weight:
388.88
Ref: TM-T4312
| 1mg | 58.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 386.00 € | ||
| 50mg | 549.00 € | ||
| 100mg | 741.00 € | ||
| 500mg | 1,476.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
