G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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WIN 55,212-2 Mesylate
CAS:131543-23-2
WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis …
Formula:
C28H30N2O6S
Purity:
98% - 99.71%
Color and Shape:
White To Off-White Solid
Molecular weight:
522.61
Ref: TM-T4458
| 1ml | 108.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
AdipoRon
CAS:924416-43-3
AdipoRon (SC-396658) is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: …
Formula:
C27H28N2O3
Purity:
98% - 99.86%
Color and Shape:
Solid
Molecular weight:
428.52
Ref: TM-T2257
| 1g | 672.00 € | ||
| 1ml | 58.00 € | ||
| 5mg | 40.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 215.00 € | ||
| 200mg | 277.00 € | ||
| 500mg | 460.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
A-582941 dihydrochloride
CAS:848591-90-2
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial
Formula:
C17H22Cl2N4
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
353.29
Ref: TM-T22016
| 1mg | 41.00 € | ||
| 1ml | 92.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 522.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BMS-986020
CAS:1257213-50-5
BMS-986020 (AM152) is a selective antagonist of LPA1.
Formula:
C29H26N2O5
Purity:
100% - 98.82%
Color and Shape:
Solid
Molecular weight:
482.53
Ref: TM-T4016
| 1mg | 51.00 € | ||
| 1ml | 89.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 520.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Ambrisentan
CAS:177036-94-1
Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not …
Formula:
C22H22N2O4
Purity:
99.65% - 99.86%
Color and Shape:
Solid
Molecular weight:
378.42
Ref: TM-T1655
| 1ml | 64.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 248.00 € | ||
| 500mg | 611.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
HJC0350
CAS:885434-70-8
HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of …
Formula:
C15H19NO2S
Purity:
99.5% - 99.53%
Color and Shape:
Solid
Molecular weight:
277.38
Ref: TM-T6536
| 1ml | 36.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 44.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 130.00 € | ||
| 100mg | 216.00 € | ||
| 200mg | 322.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
RU 24969 free base
CAS:66611-26-5
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
Formula:
C14H16N2O
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
228.29
Ref: TM-T8593
| 1ml | 72.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 92.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 383.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Conivaptan hydrochloride
CAS:168626-94-6
Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in …
Formula:
C32H26N4O2·HCl
Purity:
100% - 99.86%
Color and Shape:
Solid
Molecular weight:
535.04
Ref: TM-T6453
| 1ml | 71.00 € | ||
| 5mg | 43.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 369.00 € | ||
| 200mg | 557.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BD-1047 dihydrobromide
CAS:138356-21-5
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in …
Formula:
C13H22Br2Cl2N2
Purity:
98.13% - 99.39%
Color and Shape:
Solid
Molecular weight:
437.04
Ref: TM-T1740
| 1mg | 36.00 € | ||
| 1ml | 75.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 481.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
NLX-204 hydrochloride(2170405-10-2 free base)
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = …
Formula:
C20H23Cl2F2N3O2
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
446.32
Ref: TM-T22379L
| 1ml | 124.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
TY-52156
CAS:934369-14-9
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).
Formula:
C18H19Cl2N3O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
364.27
Ref: TM-T17183
| 1ml | 67.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 499.00 € | ||
| 200mg | 668.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Timapiprant
CAS:851723-84-7
Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 …
Formula:
C21H17FN2O2
Purity:
98.4% - 99.89%
Color and Shape:
Solid
Molecular weight:
348.37
Ref: TM-T2664
| 1ml | 37.00 € | ||
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 89.00 € | ||
| 50mg | 144.00 € | ||
| 100mg | 217.00 € | ||
| 200mg | 323.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Metoclopramide hydrochloride hydrate
CAS:54143-57-6
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug …
Formula:
C14H25Cl2N3O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
354.27
Ref: TM-T8385
| 100mg | 80.00 € | ||
| 200mg | 95.00 € | ||
| 500mg | 143.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
5'-N-Ethylcarboxamidoadenosine
CAS:35920-39-9
NECA, an adenosine receptor agonist, boosts brain extravasation of fluorescein and dextran without affecting the …
Formula:
C12H16N6O4
Purity:
98%
Color and Shape:
Powder
Molecular weight:
308.29
Ref: TM-T7340
| 1ml | 63.00 € | ||
| 5mg | 53.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 207.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Asimadoline hydrochloride
CAS:185951-07-9
Asimadoline HCl (EMD-61753) is a kappa-opioid receptor agonist for pruritus and IBS treatment.
Formula:
C27H31ClN2O2
Purity:
98.63% - 98.94%
Color and Shape:
Solid
Molecular weight:
451.01
Ref: TM-T4691
| 1mg | 35.00 € | ||
| 1ml | 81.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 488.00 € | ||
| 500mg | 1,048.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Hemokinin 1 (human) acetate(491851-53-7 free base)
Hemokinin 1 acetate: Human SP homolog, NK1 agonist (IC50: NK1 1.8 nM), proliferates B-cells, antihypertensive.
Formula:
C56H88N14O16S
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
1245.45
Ref: TM-TP1899L1
| 1mg | 98.00 € | ||
| 5mg | 214.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 545.00 € | ||
| 50mg | 779.00 € | ||
| 100mg | 1,068.00 € | ||
| 500mg | 2,126.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
AM211
CAS:1175526-27-8
AM211 (AM211 free acid) is a potent and orally bioavailable antagonist of prostaglandin D2 (PGD2) …
Formula:
C27H27F3N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
500.51
Ref: TM-T7652
| 1mg | 37.00 € | ||
| 1ml | 87.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 520.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Ro 46-2005
CAS:150725-87-4
Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 …
Formula:
C23H27N3O6S
Purity:
98.02% - 98.8%
Color and Shape:
Solid
Molecular weight:
473.54
Ref: TM-T3194
| 1ml | 49.00 € | ||
| 5mg | 44.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 292.00 € | ||
| 200mg | 422.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Lerisetron
CAS:143257-98-1
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.
Formula:
C18H20N4
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
292.38
Ref: TM-T8441
| 1mg | 64.00 € | ||
| 1ml | 120.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 320.00 € | ||
| 50mg | 470.00 € | ||
| 100mg | 675.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Cinaciguat
CAS:329773-35-5
Cinaciguat (BAY 58-2667) is a pioneering sGC activator for acute heart failure treatment.
Formula:
C36H39NO5
Purity:
98% - 99.82%
Color and Shape:
Solid
Molecular weight:
565.7
Ref: TM-T1984
| 1mg | 71.00 € | ||
| 1ml | 173.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 352.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 687.00 € | ||
| 500mg | 1,395.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
