G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
Read more
Sertindole
CAS:106516-24-9
Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).
Formula:
C24H26ClFN4O
Purity:
99.74%
Color and Shape:
Off-White To Pale Yellow Solid
Molecular weight:
440.94
Ref: TM-T5858
| 1ml | 53.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 367.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BQU57
CAS:1637739-82-2
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor …
Formula:
C16H13F3N4O
Purity:
98.36% - 98.72%
Color and Shape:
Solid
Molecular weight:
334.3
Ref: TM-T2267
| 1ml | 43.00 € | ||
| 5mg | 39.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 203.00 € | ||
| 200mg | 302.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
SB399885
CAS:402713-80-8
SB399885 is a potent, brain-penetrant, oral SR-6 antagonist with 200-fold selectivity for SR-6 receptors.
Formula:
C18H21Cl2N3O4S
Purity:
98.94%
Color and Shape:
Solid
Molecular weight:
446.35
Ref: TM-T19669
| 1mg | 94.00 € | ||
| 1ml | 200.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 244.00 € | ||
| 25mg | 402.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 762.00 € | ||
| 200mg | 1,025.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
ADL-5859
CAS:850173-95-4
ADL-5859 (ADL5859 Hydrochloride) is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against …
Formula:
C24H28N2O3·HCl
Purity:
99.11% - 99.71%
Color and Shape:
Solid
Molecular weight:
428.95
Ref: TM-T6175
| 1mg | 52.00 € | ||
| 1ml | 114.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 508.00 € | ||
| 100mg | 732.00 € | ||
| 500mg | 1,514.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Cinacalcet
CAS:226256-56-0
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular …
Formula:
C22H22F3N
Purity:
99.48%
Color and Shape:
Yellow Oil
Molecular weight:
357.41
Ref: TM-T8403
| 1ml | 52.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 142.00 € | ||
| 500mg | 343.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Bimatoprost
CAS:155206-00-1
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in …
Formula:
C25H37NO4
Purity:
100% - 99.81%
Color and Shape:
Crystalline Solid
Molecular weight:
415.57
Ref: TM-T2538
| 1ml | 58.00 € | ||
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 428.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Kisspeptin-10, human (TFA)(374675-21-5,FREE)
Kisspeptin-10 TFA: vasoconstrictor, inhibits angiogenesis & metastasis; key in kidney development & osteoblast differentiation via …
Formula:
C63H83N17O14·C2HF3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1416.46
Ref: TM-TP1345
| 1mg | 111.00 € | ||
| 5mg | 359.00 € | ||
| 10mg | 538.00 € | ||
| 25mg | 864.00 € | ||
| 50mg | 1,175.00 € | ||
| 100mg | 1,570.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Elagolix sodium
CAS:832720-36-2
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of …
Formula:
C32H29F5N3NaO5
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
653.57
Ref: TM-T5031
| 1ml | 87.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 415.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
RO 46-8443
CAS:175556-12-4
RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.
Formula:
C31H35N3O8S
Purity:
98.5% - 99.77%
Color and Shape:
Solid
Molecular weight:
609.69
Ref: TM-T3474
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,087.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
L-732138
CAS:148451-96-1
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
Formula:
C22H18F6N2O3
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
472.38
Ref: TM-T8235
| 1ml | 50.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 324.00 € | ||
| 200mg | 452.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Buclizine dihydrochloride
CAS:129-74-8
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor …
Formula:
C28H33ClN2·2HCl
Purity:
99.56%
Color and Shape:
Off-White Powder
Molecular weight:
505.95
Ref: TM-T6426
| 1ml | 49.00 € | ||
| 50mg | 35.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 59.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BGC-20-1531 hydrochloride(1186532-61-5 free base)
CAS:1962928-26-2
BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute …
Formula:
C26H25ClN2O6S
Purity:
98.02% - 99.85%
Color and Shape:
Solid
Molecular weight:
529
Ref: TM-T8993L
| 1mg | 129.00 € | ||
| 1ml | 365.00 € | ||
| 2mg | 184.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 421.00 € | ||
| 25mg | 698.00 € | ||
| 50mg | 979.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
HT-2157
CAS:303149-14-6
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective …
Formula:
C21H13F3N2O
Purity:
98.33% - 98.55%
Color and Shape:
Solid
Molecular weight:
366.34
Ref: TM-T5455
| 1ml | 63.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 295.00 € | ||
| 100mg | 495.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Lofexidine
CAS:31036-80-3
Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms.
Formula:
C11H12Cl2N2O
Purity:
98.78%
Color and Shape:
Solid
Molecular weight:
259.13
Ref: TM-T7160
| 1ml | 36.00 € | ||
| 5mg | 35.00 € | ||
| 50mg | 92.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BP 897
CAS:192384-87-5
BP 897: potent selective dopamine D3 agonist, weak D2 antagonist. Ki: 0.92 nM (D3), 61 …
Formula:
C26H31N3O2
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
417.54
Ref: TM-T9100
| 1mg | 78.00 € | ||
| 1ml | 172.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 219.00 € | ||
| 25mg | 365.00 € | ||
| 50mg | 521.00 € | ||
| 100mg | 704.00 € | ||
| 200mg | 904.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Carazolol
CAS:57775-29-8
Carazolol (Suacron) is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) …
Formula:
C18H22N2O2
Purity:
98.54% - 99.08%
Color and Shape:
Yellowish Solid
Molecular weight:
298.38
Ref: TM-T3284
| 25mg | 60.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 113.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
a-MSH, amide Acetate(581-05-5 free base)
a-MSH, amide Acetate as an endogenous neuropeptide.
Formula:
C79H113N21O21S
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
1724.94
Ref: TM-TP2212L
| 1mg | 49.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 224.00 € | ||
| 25mg | 482.00 € | ||
| 50mg | 694.00 € | ||
| 100mg | 981.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Nemifitide acetate(173240-15-8 free base)
Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.
Formula:
C35H47FN10O8
Purity:
97.97%
Color and Shape:
Solid
Molecular weight:
754.85
Ref: TM-TP1127L1
| 1mg | 117.00 € | ||
| 5mg | 217.00 € | ||
| 10mg | 385.00 € | ||
| 25mg | 641.00 € | ||
| 50mg | 911.00 € | ||
| 100mg | 1,233.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Galanin Receptor Ligand M35 TFA
Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 …
Formula:
C109H154N27F3O28
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
2347.62
Ref: TM-TP1704
| 1mg | 107.00 € | ||
| 5mg | 308.00 € | ||
| 10mg | 433.00 € | ||
| 25mg | 676.00 € | ||
| 50mg | 912.00 € | ||
| 100mg | 1,217.00 € | ||
| 200mg | 1,629.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
ONO-8130
CAS:459841-96-4
ONO-8130 is an orally available antagonist of EP1 receptor.
Formula:
C25H28N2O5S2
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
500.63
Ref: TM-T21976
| 1mg | 156.00 € | ||
| 1ml | 454.00 € | ||
| 5mg | 337.00 € | ||
| 10mg | 551.00 € | ||
| 25mg | 880.00 € | ||
| 50mg | 1,202.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
