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Complement System

Complement System

The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.

Found 156 products of "Complement System"

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  • SB290157 trifluoroacetate

    CAS:
    <p>SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).</p>
    Formula:C24H29F3N4O6
    Purity:98.93% - 99.89%
    Color and Shape:Solid
    Molecular weight:526.51
  • Lampalizumab

    CAS:
    <p>Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.</p>
    Purity:>95%
    Color and Shape:Liquid
    Molecular weight:46.96 (kDa)
  • Vesencumab

    CAS:
    <p>Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.</p>
    Purity:99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)
    Color and Shape:Liquid
  • Vilobelimab

    CAS:
    <p>Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.</p>
    Purity:99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)
    Color and Shape:Liquid
  • Sutimlimab

    CAS:
    <p>Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:144.8 kDa
  • Tesidolumab

    CAS:
    <p>Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.</p>
    Purity:99.72% (SEC-HPLC) - > 95%
    Color and Shape:Liquid
    Molecular weight:142 kDa (average)
  • Ravulizumab

    CAS:
    <p>Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.80 kDa
  • Cyclosporin A

    CAS:
    <p>Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.</p>
    Formula:C62H111N11O12
    Purity:99.00% - 99.92%
    Color and Shape:White Powder
    Molecular weight:1202.61
  • Avdoralimab

    CAS:
    <p>Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).</p>
    Purity:>95%
    Color and Shape:Liquid
  • Dexamethasone

    CAS:
    <p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46
  • EG01377 2HCl

    CAS:
    <p>EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377</p>
    Formula:C26H32Cl2N6O6S2
    Purity:98.91%
    Color and Shape:Soild
    Molecular weight:659.6
  • ARC186


    <p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>
    Color and Shape:Solid
    Molecular weight:120702.76
  • PIC1 PA TFA


    <p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>
    Formula:C71H123N19O21S2·xC2HF3O2
    Color and Shape:Solid
  • PMX 205

    CAS:
    <p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>
    Formula:C45H62N10O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:839.04
  • Claseprubart

    CAS:
    <p>Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.</p>
    Color and Shape:Liquid
  • C1s-IN-1 trihydrochloride

    CAS:
    <p>C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.</p>
    Formula:C16H22Cl3N5
    Color and Shape:Solid
    Molecular weight:390.74
  • NH2-C6-ARC186


    <p>NH2-C6-ARC186 is a derivative of the aptamer ARC186, featuring an NH2-C6 moiety that enables coupling to various peptides or molecules.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:12881
  • C3a (70-77)

    CAS:
    <p>C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.</p>
    Formula:C35H61N13O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:823.94
  • L-156,602

    CAS:
    <p>L-156,602 has a wide range of applications in life science related research.</p>
    Formula:C38H64N8O13
    Color and Shape:Solid
    Molecular weight:840.973
  • AMY-101

    CAS:
    <p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>
    Formula:C83H117N23O18S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1789.11
  • ATWLPPR Peptide TFA


    <p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>
    Formula:C42H62F3N11O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:954
  • CP-447697

    CAS:
    <p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>
    Formula:C29H26ClF2N3O2S
    Purity:99.90%
    Color and Shape:Soild
    Molecular weight:554.05
  • CP-289

    CAS:
    <p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>
    Formula:C30H35ClN2O2
    Purity:99.97%
    Color and Shape:Soild
    Molecular weight:491.06
  • Human Immunoglobulin M


    <p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>
    Color and Shape:Odour Solid
  • Factor B-IN-1

    CAS:
    <p>Factor B-IN-1 is a Factor B inhibitor.</p>
    Formula:C19H16N4O2
    Color and Shape:Solid
    Molecular weight:332.3559
  • Olendalizumab

    CAS:
    <p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>
    Color and Shape:Liquid
  • 3-O-(2'E,4'Z-Decadienoyl)ingenol


    <p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>
    Formula:C30H42O6
    Color and Shape:Solid
    Molecular weight:498.66
  • Vemircopan

    CAS:
    <p>Vemircopan is a complement factor D inhibitor.</p>
    Formula:C29H28BrN7O3
    Color and Shape:Solid
    Molecular weight:602.493
  • PMX 205 Trifluoroacetate


    <p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>
    Formula:C47H63F3N10O8
    Color and Shape:Solid
    Molecular weight:953.06
  • PMX-53

    CAS:
    <p>PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions &amp; metastasis in mice; blocks rat hypernociception.</p>
    Formula:C47H65N11O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:896.09
  • JPE-1375

    CAS:
    <p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>
    Formula:C49H63FN10O9
    Color and Shape:Solid
    Molecular weight:955.08
  • TLQP-21

    CAS:
    <p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>
    Formula:C107H170N40O26
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2432.75
  • Certepetide

    CAS:
    <p>Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.</p>
    Formula:C37H60N14O14S2
    Color and Shape:Solid
    Molecular weight:989.09
  • Compstatin TFA


    <p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>
    Formula:C68H100F3N23O19S2
    Color and Shape:Solid
    Molecular weight:1664.79
  • Pegcetacoplan acetate


    <p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>
    Color and Shape:Odour Solid
  • Complement C1s-IN-1

    CAS:
    <p>Complement C1s-IN-1 is a selective inhibitor of complement C1s,oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>
    Formula:C22H20F2N6O
    Purity:97.77%
    Color and Shape:Soild
    Molecular weight:422.43
  • Pozelimab

    CAS:
    <p>Pozelimab (REGN 3918) is a humanized antibody targeting component 5 (C5), used for research on Pozelimab disease.</p>
    Purity:98.94% (SEC-HPLC) - 98.94% (SEC-HPLC)
    Color and Shape:Liquid
  • tLyP-1 peptide

    CAS:
    <p>tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.</p>
    Formula:C31H59N15O10S
    Color and Shape:Solid
    Molecular weight:833.96
  • CK3 peptide

    CAS:
    <p>CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.</p>
    Formula:C40H72N12O12S2
    Color and Shape:Solid
    Molecular weight:977.203
  • Vensobafusp alfa

    CAS:
    <p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>
    Color and Shape:Liquid
  • Zilucoplan (PEG2)


    <p>Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).</p>
    Formula:C128H190N24O33
    Color and Shape:Solid
    Molecular weight:2593.02
  • AMY-101 TFA

    CAS:
    <p>AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9</p>
    Formula:C85H118F3N23O20S2
    Color and Shape:Solid
    Molecular weight:1903.11
  • Factor B-IN-5

    CAS:
    <p>Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.</p>
    Formula:C27H32N2O4
    Purity:98.19%
    Color and Shape:Soild
    Molecular weight:448.55
  • C5aR2 agonist P32 acetate


    <p>C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.</p>
    Formula:C54H70N16O11·xC2H4O2
    Color and Shape:Solid
    Molecular weight:1119.23 (free base)
  • Greziprubart


    <p>Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.</p>
    Color and Shape:Odour Liquid
  • 3-Phenoxybenzaldehyde

    CAS:
    <p>3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.</p>
    Formula:C13H10O2
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:198.22
  • MBL2 Protein, Mouse, Recombinant


    <p>Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:28 KDa (reducing condition)
  • Complement C2 Protein, Mouse, Recombinant (His)


    <p>Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:84.2 kDa (predicted); 91.2 kDa (reducing conditions)
  • Complement C6 Protein, Human, Recombinant (His)


    <p>Complement C6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:104 kDa (predicted); 110 kDa (reducing conditions)
  • Complement factor D-IN-1

    CAS:
    <p>Complement factor D-IN-1, a selective small-molecule inhibitor with IC50s of 0.006 μM (Thioesterolytic) and 0.05 μM (MAC Assay).</p>
    Formula:C21H19BrN6O3
    Color and Shape:Solid
    Molecular weight:483.32
  • Complement C5 Protein, Human, Recombinant (Flag)


    <p>Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:187.36 kDa (predicted); 176.6 kDa, 100.87 kDa and 72.07 kDa (reducing conditions)
  • (Z)-Leukadherin-1

    CAS:
    <p>(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.</p>
    Formula:C22H15NO4S2
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:421.49
  • Complement C2 Protein, Human, Recombinant (His)


    <p>Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Purity:98.6%
    Color and Shape:Lyophilized Powder
    Molecular weight:82.5 kDa (predicted)
  • MASP2 Protein, Mouse, Recombinant (His)


    <p>MASP2 Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.
  • C1s Protein, Human, Recombinant (His)


    <p>Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)
  • Complement C8 γ Protein, Human, Recombinant (His)


    <p>Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:22 KDa (reducing condition)
  • MASP2 Protein, Rat, Recombinant (E. coli, His)


    <p>MASP2 Protein, Rat, Recombinant (E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.
  • MBL2 Protein, Human, Recombinant (His)


    <p>Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.</p>
    Purity:> 99.9% - > 99.9%
    Color and Shape:Lyophilized Powder
    Molecular weight:31 KDa (reducing condition)
  • Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)


    <p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.
  • C1QB Protein, Human, Recombinant (His)


    <p>Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)
  • MASP2 Protein, Human, Recombinant (His)


    <p>The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.
  • C1QBP Protein, Mouse, Recombinant (His)


    <p>C1QBP Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:24.7 kDa (predicted); 32 kDa (reducing conditions)
  • Complement C5a Protein, Mouse, Recombinant, Biotinylated


    <p>Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:9 kDa (predicted)
  • Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)


    <p>Expression system: HEK293 Cells&lt;br&gt;Length: 25-1663, Full Length of Mature Protein&lt;br&gt;Activity: Not Tested</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)
  • Complement C7 Protein, Human, Recombinant (His)


    <p>Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:92.6 kDa (predicted); 92-98 kDa (reducing conditions)
  • Complement factor I Protein, Human, Recombinant (His)


    <p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:64.58 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.
  • Complement Factor MASP3 Protein, Human, Recombinant (His)


    <p>MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:95-120 KDa (reducing condition)
  • MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated


    <p>MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.
  • CFI Protein, Mouse, Recombinant (His)


    <p>CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:66.75 kDa (predicted); 126.1 kDa, 59.3 kDa and 46.7 kDa (reducing conditions)
  • MBL1 Protein, Rat, Recombinant (hFc)


    <p>MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:50.5 kDa (predicted); 56 kDa (reducing conditions)
  • MASP2 Protein, Cynomolgus, Recombinant (His)


    <p>MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result.
  • C1QTNF1 Protein, Human, Recombinant (His)


    <p>C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:37 KDa (reducing condition)
  • C1s-A subcomponent Protein, Mouse, Recombinant (His)


    <p>C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:76.6 kDa (predicted)
  • Complement C3a Protein, Mouse, Recombinant


    <p>Complement C3a Protein, Mouse, Recombinant is expressed in E.</p>
    Purity:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    Color and Shape:Lyophilized Powder
    Molecular weight:9 KDa (reducing condition)
  • Complement C3 Protein, Human, Recombinant (His)


    <p>Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Purity:SDS-PAGE: 93.4%; SEC-HPLC: 94.7% - SDS-PAGE: 95.5%; SEC-HPLC: 92.6%
    Color and Shape:Lyophilized Powder
    Molecular weight:186.43 kDa (predicted)
  • Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)


    <p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
  • Complement Factor D/CFD Protein, Human, Recombinant (hFc)


    <p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
  • Complement C5 Protein, Human, Recombinant (His & FLAG)


    <p>Complement C5 Protein, Human, Recombinant (His &amp; FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.</p>
    Purity:96.1%
    Color and Shape:Lyophilized Powder
    Molecular weight:188.8 kDa (predicted)
  • Complement C3 Protein, Cynomolgus, Recombinant (His)


    <p>Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Purity:90.3%
    Color and Shape:Lyophilized Powder
    Molecular weight:186.40 kDa (predicted)
  • Complement C3a Protein, Human, Recombinant


    <p>Complement C3a Protein, Human, Recombinant is expressed in E.</p>
    Purity:>99.99% - Greater than 95% as determined by reducing SDS-PAGE.
    Color and Shape:Lyophilized Powder
    Molecular weight:13 KDa (reducing condition)
  • Complement C5 Protein, Cynomolgus, Recombinant


    <p>Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:8.41 kDa (predicted); 12.42 kDa (reducing conditions)
  • Complement C2 Protein, Human, Recombinant (hFc)


    <p>Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:110 kDa (predicted); 110-130 kDa (reducing condition, due to glycosylation)
  • Complement C7 Protein, Human, Recombinant (hFc)


    <p>Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:118 kDa (predicted); 118 kDa (reducing conditions)
  • Complement factor I Protein, Mouse, Recombinant (His)


    <p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:66.39 kDa (predicted). Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Tris-Bis PAGE result.
  • Complement C5a Protein, Mouse, Recombinant


    <p>Complement C5a Protein, Mouse, Recombinant is expressed in E.</p>
    Purity:97.4%
    Color and Shape:Lyophilized Powder
    Molecular weight:9 kDa (predicted)
  • Complement C5 Protein, Cynomolgus, Recombinant (His)


    <p>Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)
  • Complement C2 Protein, Cynomolgus, Recombinant (His)


    <p>Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
  • Complement C3 Protein, Mouse, Recombinant (aa 994-1310, His)


    <p>Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:36.34 kDa (predicted); 32.39 kDa (reducing conditions)
  • C1QBP Protein, Human, Recombinant (His)


    <p>C1QBP Protein, Human, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:24.8 kDa (predicted); 36 kDa (reducing conditions)
  • Compstatin control peptide acetate

    CAS:
    <p>Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.</p>
    Formula:C66H101N23O17
    Purity:99.02%
    Color and Shape:Odour Solid
    Molecular weight:1488.65
  • BCX 1470 methanesulfonate

    CAS:
    <p>BCX 1470 inhibits factor D &amp; C1s better than trypsin (IC50: 96 nM &amp; 1.6 nM, 3.4- &amp; 200-fold).</p>
    Formula:C15H14N2O5S3
    Color and Shape:Solid
    Molecular weight:398.48
  • PMX 53 acetate(219639-75-5 free base)

    CAS:
    <p>PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50</p>
    Formula:C49H69N11O9
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:956.16
  • Eculizumab

    CAS:
    <p>Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5</p>
    Purity:98.20%
    Color and Shape:Liquid
    Molecular weight:148 kDa
  • ADH-503

    CAS:
    <p>ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.</p>
    Formula:C27H28N2O5S2
    Purity:97.03% - >99.99%
    Color and Shape:Solid
    Molecular weight:524.7
  • Danicopan

    CAS:
    <p>Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.</p>
    Formula:C26H23BrFN7O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:580.41
  • JR14a

    CAS:
    <p>JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.</p>
    Formula:C25H26Cl2N4O3S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:533.47
  • Compstatin

    CAS:
    <p>Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.</p>
    Formula:C66H99N23O17S2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:1550.77
  • Iptacopan hydrochloride

    CAS:
    <p>Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.</p>
    Formula:C25H31ClN2O4
    Purity:98.89% - 99.89%
    Color and Shape:Solid
    Molecular weight:458.98
  • Avacopan

    CAS:
    <p>Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.</p>
    Formula:C33H35F4N3O2
    Purity:99.47% - 99.9%
    Color and Shape:Solid
    Molecular weight:581.64
  • Leukadherin-1

    CAS:
    <p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>
    Formula:C22H15NO4S2
    Purity:98.49% - 98.93%
    Color and Shape:Solid
    Molecular weight:421.49