Others

<p>Introducing our 4-Nitrophenyl 2,3,4-tri-O-acetyl-6-O-(2,3,4,6-tetra-O-[4-methoxybenzyl]-a-D-glucopyranosyl)-a-D-glucopyranoside, an advanced chromogenic pNP enzyme substrate designed for high performance and superior results. This cutting-edge substrate ensures excellent outcomes in various enzymatic assays, including glycosidase and glycosyltransferase, due to its unique composition and significant sensitivity. Offering rapid color development and clear visualization, this substrate is perfect for research or industrial applications.</p>

<p>4-Nitrophenyl 2-acetamido-3,6-di-O-acetyl-2-deoxy-b-D-glucopyranoside is a versatile chromogenic pNP enzyme substrate designed to offer superior results for detecting enzyme activity in research and diagnostic applications. This substrate enables faster, more accurate, and reliable detection of hydrolase enzymes, making it ideal for various research and testing needs, such as studying enzyme kinetics, screening inhibitors, and profiling enzyme specificity.</p>

<p>4-Chloro-2-nitrophenyl b-D-galactopyranoside is a fluorogenic substrate that is used in diagnostic testing, such as food and environmental testing. 4-Chloro-2-nitrophenyl b-D-galactopyranoside is an enzyme substrate that can be used to measure the activity of beta galactosidase. This substrate is also chromogenic, which means that it will change color when exposed to the enzyme. 4CNPGalA has been shown to be an excellent ligand for beta galactosidase and can be used in conjugation reactions with other molecules.</p>

<p>4-Nitrophenyl 3-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-glucopyranoside is a chromogenic substrate that is used to test for the presence of an enzyme. It reacts with the enzyme to produce a light signal that can be detected by a spectrophotometer. The CAS number for this compound is 832476-41-8. This compound has been tested and found to be of high quality and purity. 4NP3OBG is also suitable for use in culture media, food testing, and as a fluorogenic substrate.</p>

<p>4-nitrophenyl 2-acetamido-3-O-[2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-3,4,6-tri-O-acetyl -D -galactopyranosyl]-2 deoxy 6 O trityl b D glucopyranoside is a chemiluminescent substrate that can be used in biochemical assays. It reacts with oxygen to produce light when it is excited by a UV or blue light source. This product has been tested for purity and quality by HPLC analysis and spectroscopy.</p>

<p>4-Nitrophenyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a chemiluminescent substrate that is used in the detection of enzymes. It is also used to measure the activity of beta-glucosidase, alpha-galactosidase, and alkaline phosphatase. The product has been tested for environmental sensitivity and has not shown any effects on bacterial growth. 4-Nitrophenyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside can be used as a high quality stain for histological sections and immunohistochemical studies. This product has been tested for staining properties with different dyes and has shown no interference with the staining process.</p>

<p>Aldol® 518 myo-inositol-1-phosphate is a chromogenic and fluorogenic enzyme substrate used for detection of phosphatidyl-inositol specific phospholipase C activity (PI-PLC, EC 4.6.1.13). The colorless enzyme substrate is cleaved by PI-PLC or PI-PLC-positive microorganisms grown in liquid or solid media, yielding an intense red coloration. In combination with Aldol® 355 fluorescence enhancer, red fluorescence can also obtained. Aldol® 518 myo-inositol-1-phosphate is suitable for use in liquid and solid media, under aerobic as well as anaerobic conditions.</p>

<p>4-Nitrophenyl 2,6-di-O-benzoyl-a-D-galactopyranoside is a specialized chromogenic substrate for the accurate evaluation of α-galactosidase activity. Upon enzymatic hydrolysis, it generates the chromophore 4-nitrophenol, which can be conveniently quantified by absorbance spectroscopy. The substrate features a unique benzoylated galactopyranoside moiety for enhanced selectivity and compound stability. This high-quality substrate is perfect for various research, analytical, and diagnostic applications involving α-galactosidase detection or quantification.</p>

<p>2-Nitrophenyl 2-acetamido-2-deoxy-a-D-galactopyranoside is a fluorogenic substrate that is used in enzyme assays. It can be used as a chromogenic substrate or conjugate with an enzyme to detect the presence of glucose.</p>

<p>N-(4-Nitrophenyl)-D-glucopyranosylamine is a conjugate that is used in food testing, environmental testing, and diagnostics. It is a fluorogenic substrate that reacts with the enzyme glucose oxidase to produce a yellow color. This product has high purity and quality and CAS No. 553-03-6. It also has bioluminescence properties.</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-a-D-galactopyranoside is a fluorescent substrate that can be used in chemiluminescent assays. It is a high purity, high quality chemical that has been tested for culture media, environmental testing and bioluminescence. This product is an excellent choice for use in diagnostics, chromogenic substrates, enzyme substrates and food testing.</p>

<p>2-Nitrophenyl 2,3-di-O-acetyl-4-O-triethylsilyl-b-D-xylopyranoside is a chromogenic substrate for enzmatic assays to measure xylosidase activity. It is a derivative of xylose that can be hydrolyzed by xylosidase to release the yellow-colored 2-nitrophenyl group, which can be detected spectrophotometrically. By modifying the xylose molecule with acetyl and triethylsilyl groups, the enzyme substrate becomes more stable and resistant to degradation. This substrate is commonly used in the study of plant biomass degradation and in the detection of xylosidase activity in microorganisms.</p>

<p>[2-Methoxy-4-(2-nitrovinyl)phenyl] b-D-galactopyranoside (MNVP-gal) is a chromogenic enzyme substrate that is commonly used to detect the activity of beta-galactosidase in biological samples. MNVP-gal produces a distinctive magenta color when hydrolyzed by beta-galactosidase, making it particularly useful for applications where visual detection is necessary. This substrate is also resistant to endogenous proteases, making it well-suited for use in cellular and tissue preparations.</p>

<p>2-Nitrophenyl 2,2',3,3',4'-penta-O-acetyl-b-D-xylobioside is an oligosaccharide that is used as a substrate for the transport of nucleic acid molecules. It can be used to study the function of membrane transport proteins and their homologues. This compound has been shown to inhibit the growth of corynebacterium glutamicum and trisaccharide emissions.</p>

<p>4-Nitrophenyl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside enzyme substrate is a versatile and reliable reagent for measuring glucosidase activity. It is an ideal substrate for use in assays to detect β-glucosidase activity in a variety of applications, including for in vitro and in vivo studies, and it has been widely used in the pharmaceutical and biotechnology industries. This chromogenic pNP enzyme substrate is designed for effective and precise analysis with good sensitivity and low background signals.</p>

<p>5-Bromo-3-indolyl decanoate (BID) is a chromogenic enzyme substrate often used for the detection of lipase activity. It is hydrolyzed by lipase to produce a blue-violet product, which can be detected visually or by spectrophotometry. BID is particularly useful for the detection of microbial lipases in food and environmental samples. It is commonly used in a wide range of biochemical, biological, and environmental testing applications that require precise lipase enzyme analysis.</p>

<p>6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid (CA) is an impurity found in the drug lorazepam. It is a chemical intermediate that is not active as a pharmaceutical agent, but has been studied for use in treating epilepsy and other neurological disorders. CA is an excipient used to manufacture other drugs such as salicylic acid and the surfactant sodium lauryl sulfate. It has been shown to have acidic properties and can be used as a surfactant, which is helpful in chromatographic methods to separate molecules by size. CA also binds to chloride ions, which are necessary for the proper functioning of many cellular processes. CA's molecular weight is 322 daltons and it exhibits no pharmacological activity.</p>

<p>4-Nitrophenyl 2,4,6-tri-O-acetyl-3-O (2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-a-D-glucopyranoside is a chemiluminescent substrate that can be used for the detection of aminoglycosides in biological fluids. It is a high purity and high quality product with CAS No. 482743. The product has been tested for safety and purity using culture media and environmental testing. This product may be used as a bioluminescence substrate to detect the presence of aminoglycosides in samples such as urine, serum or plasma. 4NTPAGDG is also useful as a fluorogenic substrate for diagnostics and enzyme substrates for food testing.</p>

<p>Aldol 496 acetate is a chromogenic substrate for the enzyme Aldolase. It is also used as a ligand to detect the presence of Aldolase in biological fluids and tissues. This product is designed for Food testing, Diagnostics, Chromogenic substrate, Staining, Enzyme substrate, Bioluminescence, Fluorogenic substrate, Chemiluminescence, and Culture media. Aldol 496 acetate is an organic chemical with high purity and high quality.</p>

<p>5-Bromo-4-chloro-3-indolyl b-D-galactopyranoside 6-sulphate (BCIGS) is a chemiluminescent substrate that reacts with an enzyme to produce light. It has been used for the detection of various substances, including 5'-nucleotidase, 5'-adenosine monophosphate phosphohydrolases, and alkaline phosphatase. BCIGS can be used as a chromogenic substrate in the fluorometric assay of glucose oxidase and galactose oxidase. BCIGS is also used as a ligand in immunological reactions such as immunodiffusion, immunoelectrophoresis, and radioimmunoassay.</p>

<p>4-Nitrophenyl 4,6-benzylidene-3-O-(2,3,4,6-tetra-O-[4-methoxybenzyl]-a-D-glucopyranosyl)-a-D-glucopyranoside is a chemiluminescent substrate used for the detection of various enzymes. This substrate is commonly used in enzyme assays to measure the activity of β-galactosidase, α-amylase, and β-lactamase. The product can be used in diagnostic applications such as food testing and bacterial identification.</p>

<p>Chromogenic substrate targeting cellulase</p>

<p>2-(5'-Chloro-2'-hydroxyphenyl)-6-chloro-4(3H)-quinazolinonyl a-D-N-acetylgalactosamine is an inhibitor of bacterial cell wall synthesis. It has been shown to inhibit the enzymatic activity of beta-lactamase, which is an enzyme that breaks down beta-lactam antibiotics. 2-(5'-Chloro-2'-hydroxyphenyl)-6-chloro-4(3H)-quinazolinonyl a-D-N-acetylgalactosamine can be used for the treatment of infections caused by bacteria such as methicillin resistant Staphylococcus aureus. This compound has been shown to have low toxicity and does not cause any significant side effects in animals.</p>

<p>5-Bromo-6-chloro-3-indolyl b-D-glucuronide (5BCIG) is an antibiotic that inhibits bacterial growth by binding to the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5BCIG is detectable in tissues, and quantified in blood. It encodes a protein to the cell cytoplasm. The sensitivity of 5BCIG against clostridium perfringens was found to be 10 times higher than that of penicillin G or erythromycin. 5BCIG has optimal activity against clostridium perfringens when expressed functionally as a polypeptide.</p>

<p>5-Bromo-6-chloro-3-indoxyl choline phosphate is a chemiluminescent substrate for the detection of bacterial activity. It reacts with an enzyme, luciferase, which is present in a variety of living cells. The reaction produces light. This product has been tested for environmental and food safety by the manufacturer. 5-Bromo-6-chloro-3-indoxyl choline phosphate is used as a diagnostic tool to determine the presence of bacteria in humans, animals, and plants. It can be used to measure levels of bacteria in culture media, water samples, and food products. 5-Bromo-6-chloro-3-indoxyl choline phosphate can also be used as a substrate for enzymes such as phosphatases or esterases that catalyze reactions with substrates with brominated or chlorinated groups.</p>

<p>4-Nitrophenyl 6'-deoxy-6'-(2-pyridylamino)-a-D-penta-(1-4)-glucopyranoside is a fluorescent substrate for the enzyme beta glucosidase. It is a chemiluminescent reagent that can be used to measure beta glucosidase activity. The substrate is an excellent high quality chemical and has been tested for environmental safety, heavy metal content and staining. 4-Nitrophenyl 6'-deoxy-6'-(2-pyridylamino)-a-D-penta-(1-4)-glucopyranoside is a chromogenic substrate that can be used in diagnostic testing, such as bioluminescence or fluorogenic assay. This product can also be used as a culture media additive or food testing agent.</p>

<p>Histamine (Scombrotoxin) fish poisoning is the most frequent cause of fish poisoning incidents today. Cymit Quimica's BCM®; Histamine-producingbacteria Broth (C-0450) is a growth medium for the detection of histamine-producing bacteria in food and water samples. The medium contains an indicator that turns orange to red due to metabolites released by histidine decarboxylase.</p>

<p>2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-xylopyranoside (DNFX) is a transglycosylation reagent that can be used to inactivate enzymes that catalyze the synthesis of xylosides. DNFX undergoes a covalent reaction with these enzymes and inhibits them by binding to the active site. DNFX catalyses the reaction between xylose and nucleophiles such as hydroxide ions, thiols, or amines. DNFX also has a catalytic effect on electrospray ionization and can be used for the detection of nucleophile activity.</p>

<p>4-Nitrophenyl 2-O-(α-L-fucopyranosyl)-β-D-galactopyranoside is a chromogenic enzymatic substrate for the detection and quantification of glycosidases, such as fucosidases and galactosidases. Upon enzymatic cleavage, the substrate releases the p-nitrophenol chromophore, which can be quantified via colorimetric analysis. This pNP-conjugated compound enables the rapid, sensitive, and high-throughput detection of enzyme activity in various applications, including enzymatic assays, inhibitor screening, and mechanistic studies. Its precise specificity for α-L-fucopyranosyl and β-D-galactopyranoside moieties makes it an excellent tool for advancing research in glycobiology and related fields.</p>

<p>Chromogenic substrate for beta-D-galactosidase yielding a brown precipitate upon cleavage.</p>

<p>Aldol® 515 L-proline amide is a chromogenic and fluorogenic enzyme substrate used for detection of L-proline aminopeptidase activity. The colorless enzyme substrate is cleaved by L-proline aminopeptidase produced by microorganisms grown in liquid or solid media, yielding red-orange color. In addition, red fluorescence signals are generated when a fluorescence enhancer or a suitable matrix is present. Aldol® 515 L-proline amide is suitable for use under aerobic and anaerobic conditions.</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-6-O-trityl-b-D-glucopyranoside offers unmatched versatility as a chromogenic pNP substrate for detecting b-D-glucopyranosidase activity. The substrate is specifically designed to produce a yellow 4-nitrophenol product upon enzyme hydrolysis, which can be measured using absorbance spectroscopy. The unique tritylated glucopyranoside group ensures improved compound stability and selectivity while providing ease of handling. This versatile substrate is ideal for a broad range of biochemical, research, and diagnostic applications.</p>

<p>Substrate for a-N-acetyl-galactosaminidase</p>

<p>4-Nitrophenyl 2,3,4-tri-O-acetyl-a-D-glucopyranoside is a high quality chemical used in the development of various diagnostic and research applications. It is also used in the production of enzymatic substrates for enzyme activity assays. 4NPTAG is a chromogenic substrate that produces chemiluminescence when it reacts with an oxidizing agent and has been shown to be very effective as a fluorogenic substrate for protein kinases. This compound has been shown to bind to ligands and can be used as a bioluminescent reporter for molecular biology applications. The CAS number for this product is 54973-14-0.</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-4,6-O-p-methoxybenzylidene-a-D-galactopyranoside is a chromogenic substrate designed for the detection and quantification of enzyme activity. This methoxybenzylidene-protected compound is specifically designed to be cleaved by enzymes, releasing a yellow 4-nitrophenol product that can be easily measured spectrophotometrically. This allows for accurate and sensitive analysis of enzyme kinetics, inhibition studies, and substrate specificity determination in various applications.</p>

<p>2-Nitrophenyl laurate is a fatty acid that is not able to be degraded and has a high affinity for magnetic particles. It can be used in the immobilization of bacteria, such as Stenotrophomonas maltophilia, which are resistant to many antibiotics. 2-Nitrophenyl laurate also inhibits the enzyme lipolytic enzymes, which are responsible for the degradation of phospholipids in the cell membrane. This inhibition may lead to an increase in bacterial susceptibility to antibiotics. 2-Nitrophenyl laurate is a synthetic substrate that can be used to study the regulation of lipolytic enzymes by regulatory proteins.</p>

<p>Aldol 491 acetate is a food and environmental testing chemical, which can be used for the detection of bacteria. Aldol 491 acetate provides a chromogenic substrate for the detection of enzymes and can be used as a substrate in enzyme-linked immunosorbent assay (ELISA) procedures. Aldol 491 acetate also has chemiluminescent properties and can be used as a fluorogenic substrate.</p>

<p>Chromogenic substrate targeting amylase</p>

<p>Espresso-Gal (Espresso-beta-D-galactopyranoside) is a chromogenic indicator for beta-galactosidase activity. The colorless product is cleaved by lactose-utilizing bacteria in liquid media or on agar plates and yields an espresso brown colored precipitate. Espresso-Gal can also be used as detecting agent for beta-galactosidase activity in reporter gene assays or for identification of positive transformants on agar plates when using the α-complementation approach. Read more in the Application Notes.</p>

<p>2-Methyl-4-nitrophenyl b-D-galactopyranoside is a chemiluminescent substrate that is used in various applications. It is a ligand that binds to the enzyme beta-galactosidase and is used in diagnostics for detecting the presence of the enzyme. 2-Methyl-4-nitrophenyl b-D-galactopyranoside has been shown to be an appropriate substrate for chemiluminescence reactions, such as those used in diagnostic or research applications. The product also has been tested for potential toxicity and found not to be toxic at concentrations up to 100mg/mL. This product can be used in a variety of applications, including food testing, bacterial culture media, and environmental testing.</p>

<p>2,4-Dinitrophenyl b-D-cellobioside is a chemiluminescent substrate that is used to detect the activity of enzymes and other proteins. It can be conjugated with an antibody or other ligand for use in diagnostic purposes. 2,4-DNPBC is a pure compound with a high quality that does not contain any other impurities. Its CAS number is 157956-96-2.</p>

<p>5-Bromo-6-chloro-1H-indol-3-yl-a-D-mannopyranoside is a chromogenic substrate that yields a magenta-colored product after cleavage. The chromophore 5-bromo-6-chloro-indoxyl is released, generating the observable color. It is used in lysosomal storage disorder screening.</p>

<p>S-(4-Nitrophenyl)mercapturic acid (S-NPMA) is the major metabolite of 4-nitrophenol, which is a precursor to dyes and pharmaceuticals. S-NPMA has been detected in urine samples from humans, rats, and mice. The main metabolic pathway for S-NPMA is an oxidative conversion by cytochrome P450 enzymes. S-NPMA has been found to be a useful biomarker for the presence of polycyclic aromatic hydrocarbons in wastewater and human urine. The levels of this compound have also been shown to increase with age in humans.</p>

<p>4-Nitrophenyl b-D-thiomannopyranoside acts as a substrate for β-mannosidase and thioglycoligase. Upon enzymatic cleavage, these substrates release 4-nitrophenol, a yellow chromophore that can be detected spectrophotometrically at 405 nm, facilitating quantitative measurements of enzymatic activity. Consequently, these substrates are widely used in biochemical research, clinical diagnostics, and drug discovery for evaluating the function of specific enzymes in various biological processes.</p>

<p>Abiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.</p>

<p>4-Nitrophenyl O-(N-acetyl-a-neuraminosyl)-(2-3)-b-D-galactopyranosyl-(1-4)-2-acetamido-2-deoxybDglucopyranoside is a fluorescent compound that has been used as a substrate in enzyme assays. It has been shown to be an effective ligand for the enzyme beta galactosidase, which hydrolyzes the substrate to produce 4nitrophenol and o-(Nacetyl)a-neuraminic acid. This product is CAS No. 501427-92-5 and can be used as a high purity, high quality reagent for conjugation.</p>

<p>4-Nitrophenyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-a-D-galactopyranoside is a chromogenic substrate designed for the detection and quantification of enzyme activity. This tetra-acetylated compound is specifically designed to be cleaved by enzymes, releasing a yellow 4-nitrophenol product that can be easily measured spectrophotometrically, allowing for accurate and sensitive analysis of enzyme kinetics and inhibition studies.</p>

<p>4-Nitrophenyl 2-acetamido-3-azido-2,3-dideoxy-b-D-galactopyranoside is a fluorogenic substrate for beta-galactosidase. It has been used in the detection of beta-galactosidase activity in culture media, and for the detection of beta-galactosidase activity in environmental samples. 4NPAG can be conjugated to a variety of molecules, including antibodies, proteins, nucleotides, and oligonucleotides. 4NPAG can be used as an enzyme substrate for both chromogenic and fluoroquinolone substrates.</p>

<p>Aldol® 458 phosphate is a chromogenic and fluorogenic enzyme substrate used for detection of phosphatase activity. The colorless enzyme substrate is cleaved by phosphatases secreted by bacteria grown in liquid media, yielding yellow color and green fluorescence. Aldol® 458 phosphate can also be used in assays involving phosphatase-coupled antibodies in immunoassay applications (ELISA). Aldol® 458 phosphate can be used under aerobic and anaerobic conditions.</p>

<p>The 4-Nitrophenyl 2-acetamido-2-deoxy-4-O-[2-O-(a-L-fucopyranosyl)-b-D-galactopyranosyl]-b-D-glucopyranoside is a specialized pNP enzyme substrate designed to study fucosyl-galactose-dependent enzymes. This chromogenic substrate is valuable for researchers investigating glycosyltransferase activity, structure-function relationships of glycan-binding proteins, and regulation of cellular signaling pathways involving fucose modifications. Its high specificity and sensitivity ensure accurate measurements in diverse experimental setups, and its chromogenic detection system facilitates rapid and reliable analysis.</p>