Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Found 2393 products of "Ketones and derivatives"
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JNJ-1661010
CAS:<p>JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.</p>Formula:C19H19N5OSPurity:99.79% - 99.97%Color and Shape:SolidMolecular weight:365.45Quinine dihydrochloride
CAS:<p>Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).</p>Formula:C20H26Cl2N2O2Purity:99.79% - 99.97%Color and Shape:White SolidMolecular weight:397.34Flupirtine
CAS:<p>Flupirtine(D 9998) is a selective neuronal potassium channel opener as well as shows properties of NMDA receptor antagonist.</p>Formula:C15H17FN4O2Color and Shape:SolidMolecular weight:304.32Acetophenone
CAS:<p>Acetophenone (Phenylethanone) is used in chemical synthesis and as a fragrance.</p>Formula:C8H8OPurity:99.53%Color and Shape:Acetophenone Is A Colorless Liquid LiquidMolecular weight:120.15Butyrophenone
CAS:<p>Butyrophenone (NSC-8463) is a chemical compound. Some of its derivatives are used to treat various psychiatric disorders.</p>Formula:C10H12OPurity:99.84%Color and Shape:Colourless To Yellow LiquidMolecular weight:148.2Nordihydrocapsaicin
CAS:<p>Nordihydrocapsaicin is an analog and congener of capsaicin, belonging to the capsaicinoid class of compounds found in Capsicum chili peppers.</p>Formula:C17H27NO3Purity:99.53% - 99.59%Color and Shape:SolidMolecular weight:293.4Methyl 4-hydroxy-4-methyl-2-(3-nitrophenyl)-6-oxocyclohexane-1-carboxylate
Formula:C15H17NO6Molecular weight:307.30Medetomidine hydrochloride
CAS:<p>Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.</p>Formula:C13H16N2·HClPurity:99.96%Color and Shape:White Or Off White Crystalline PowderMolecular weight:236.744-Acetaminophen Sulfate Potassium Salt
CAS:Controlled ProductFormula:C8H8NO5S·KColor and Shape:BeigeMolecular weight:269.32Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Formula:C20H22N2O2Color and Shape:White To Light BeigeMolecular weight:322.403-Benzoyl-α-methylbenzeneacetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F<br>Applications 3-Benzoyl-α-methylbenzeneacetonitrile (Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F) was used as a substrate to study the enantioselectivity of nitrile hydratase from Rhodococcus equi A4.<br>References Martinkova, L., et al.: Biotechnol. Lett. 18, 1073 (1996); Layh, N., et al.: Botehcnol. Lett. 17, 187 (1995);<br></p>Formula:C16H13NOColor and Shape:WhiteMolecular weight:235.286-Methoxy-2-naphthaleneacetic Acid-d3 (Desmethyl Naproxen-d3)
CAS:Controlled Product<p>Applications A labelled metabolite of Nabumetone (N200500). A competitive, non-selective COX inhibitor.<br>References Turpeinen et. al.: Drug Metabolism and Dispositoin, 37: 1017 (2009); Daniels, F., et al.: J. Invest. Dermatol., 44, 259 (1965), Bosca, F., et al.: Photochem. Photobiol., 71, 173 (2000),<br></p>Formula:C13H9D3O3Color and Shape:White To Off-WhiteMolecular weight:219.253-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Controlled Product<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C11H9D5N2O4S•C2HF3O2Color and Shape:NeatMolecular weight:389.36Acetaminophen-d4 (major)
CAS:Controlled Product<p>Applications Acetaminophen-d4 (major) is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C82H4H5NO2Color and Shape:Off-WhiteMolecular weight:155.19(-)-Tramadol Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Formula:C16H25NO2·ClHColor and Shape:NeatMolecular weight:299.84Niflumic Acid-d5 (Major)
CAS:Controlled Product<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formula:C13H4D5F3N2O2Color and Shape:NeatMolecular weight:287.25Acetaminophen Mercapurate Disodium
CAS:<p>Applications Acetaminophen Mercapurate Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)<br></p>Formula:C13H14N2O5S·2NaColor and Shape:NeatMolecular weight:356.31α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Formula:C12H18OColor and Shape:Colourless LiquidMolecular weight:178.27m-Isobutyl Ibuprofen
CAS:<p>Impurity Ibuprofen EP Impurity A<br>Applications m-Isobutyl Ibuprofen (Ibuprofen EP Impurity A) is an Ibuprofen (I140000) impurity used in the study of potent noncompetitive interleukin-8 inhibitors.<br>References Moriconi, A. et al.: J. Med. Chem., 50, 3984 (2007); Allegretti, M. et al.: J. Med. Chem., 48, 4312 (2005);<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.281-[3-(6-bromo-2H-1,3-benzoxazin-3(4H)-yl)phenyl]ethanone
CAS:Purity:95.0%Molecular weight:332.1969909667969(3-Benzoylphenyl)acetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity I<br>Applications (3-Benzoylphenyl)acetonitrile (Ketoprofen EP Impurity I) is a Ketoprofen intermediate.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Formula:C15H11NOColor and Shape:Colourless To Light YellowMolecular weight:221.253-(N-Acetyl-L-cystein-S-yl) Acetaminophen
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Paracetamol Mercapturate is a metabolite of Acetaminophen (A161220) (1,2). Acetaminophen is a widely used analgesic and antipyretic drug. It can also be used in biological study of urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.<br>References (1) Trettin, A., et al.: J. Chromatogr. B., 963, 105 (2014) (2) Pickering, G., et al.: Clin. Pharmacol. Ther., 90, 707 (2011)<br></p>Formula:C13H16N2O5SColor and Shape:NeatMolecular weight:312.344'-Methylacetophenone
CAS:Controlled Product<p>Impurity Celecoxib Impurity<br>Applications 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.<br>References Dwivedi, U.N. et al.: Acta Polym., 39, 596 (1988); Opdyke, D.L.J. et al.: Food Cosm. Toxicol., 12, 933 (1974);<br></p>Formula:C9H10OColor and Shape:NeatMolecular weight:134.18rac-Acetaminophen Mercapturate-d5 (Major)
CAS:Controlled Product<p>Applications rac-Acetaminophen Mercapturate-d5 (Major), is a labeled analogue and free acid of 3-(N-Acetyl-L-cystein-S-yl) Acetaminophen Disodium Salt (A172100), which is a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References van der Hooft, J.,et al.: Metabolomics, 12, 1 (2016)<br></p>Formula:C13H11D5N2O5SColor and Shape:NeatMolecular weight:317.375-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Controlled ProductFormula:C13H14N2Color and Shape:NeatMolecular weight:198.26Propyphenazone
CAS:Controlled Product<p>Applications Analgesic; antipyretic; anti-inflammatory.<br>References Ertl, P., et al.: J. Med. Chem., 43, 3714 (2000), Sun, C., et al.: J. Pharm. Sci., 93, 646 (2004),<br></p>Formula:C14H18N2OColor and Shape:NeatMolecular weight:230.314-Chlorobenzoic Acid
CAS:Controlled Product<p>Impurity Acemetacin EP Impurity A / Bezafibrate EP Impurity B<br>Applications A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>Formula:C7H5ClO2Color and Shape:White To Off-WhiteMolecular weight:156.571-(2-(CYCLOPROPYLMETHOXY)-6-(4-METHOXYBENZYLOXY)PHENYL)ETHANONE
CAS:Purity:95.0%Molecular weight:326.3919982910156p-Phenetidine-d5 Hydrochloride
CAS:Controlled Product<p>Applications Labelled p-Phenetidine (P296300). A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.<br>References Green, C., et al.: Br. Med. J., 1, 162 (1969), Nelson, S., et al.: J. Med. Chem., 25, 753 (1982), Nicholls, A., et al.: Xenobiotica, 27, 1175 (1997),<br></p>Formula:C8H7D5ClNOColor and Shape:NeatMolecular weight:178.67Capsaicin-5,7-dene
Controlled ProductFormula:C18H25NO3Color and Shape:Off-WhiteMolecular weight:303.396Nordihydrocapsaicin
CAS:Controlled Product<p>Applications Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>Formula:C17H27NO3Color and Shape:Off-WhiteMolecular weight:293.404′-(4-Fluorophenoxy)acetophenone
CAS:Formula:C14H11FO2Purity:97%Color and Shape:SolidMolecular weight:230.238Dihydro Ketoprofen (Mixture of Diastereomers)
CAS:<p>Applications A metabolite of Ketoprofen.<br>References Jamali, F., et al.: J. Pharma. Sci., 79, 460 (1990), Lindon, J., et al.: Drug Metab. Rev., 29, 705 (1997), Akira, K., et al.: Drug Metab. Dispos., 26, 457 (1998), Rudy, A., et al.: J. Clin. Pharmacol., 38, 3S (1998),<br></p>Formula:C16H16O3Color and Shape:NeatMolecular weight:256.30Dihydro Capsaicin
CAS:Controlled Product<p>Applications Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ralevic, V., et al.: Biochem. Pharmacol., 65, 143 (2003), Thompson, R., et al.: Anal. Bioanal. Chem., 381, 1432 (2005), Tuoya., et al.: Life Sci., 78, 1515 (2006),<br></p>Formula:C18H29NO3Color and Shape:White To Off-WhiteMolecular weight:307.434-Acetaminophen-d3 Sulfate Potassium Salt
CAS:Controlled Product<p>Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formula:C8H5D3KNO5SColor and Shape:NeatMolecular weight:272.33p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Formula:C11H14O2Color and Shape:WhiteMolecular weight:178.231-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
CAS:Purity:97.0%Molecular weight:426.4880065917969Medetomidine-13C,d3 Hydrochloride
CAS:Controlled Product<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formula:CC122H3H13N2·ClHColor and Shape:White To Light YellowMolecular weight:240.75rac α-Hydroxy Ibuprofen
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity M<br>Applications A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.<br>References Williams, K., et al.: Pharm. Ther., 46, 273 (1990), Evans, A., et al.: Eur. J. Clin. Pharmacol., 42, 237 (1992), Tucker, G., et al.: Lancet, 355, 1085 (2000), Tan, S., et al.: Xenobiotica, 32, 683 (2002), Fura, A., et al.: J. Pharm. Biomed. Anal., 32, 513 (2003),<br></p>Formula:C13H18O3Color and Shape:White To Off-WhiteMolecular weight:222.28rac Ketorolac
CAS:Controlled Product<p>Applications Ketorolac is an analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C15H13NO3Color and Shape:Off White SolidMolecular weight:255.274′-Methoxyacetophenone
CAS:Formula:C9H10O2Purity:99.0%Color and Shape:Solid, White crystallineMolecular weight:150.177N-Acetyl-4-benzoquinone Imine
CAS:Controlled Product<p>Stability Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive<br>Applications N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).<br>References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)<br></p>Formula:C8H7NO2Color and Shape:NeatMolecular weight:149.152-Butyl-6-methoxynaphthalene
CAS:Controlled Product<p>Applications 2-Butyl-6-methoxynaphthalene is an impurity of Nabumetone (N200500), an anti-inflammatory and antibacterial agent.<br>References Najera, C., et al.: Adv. Syn. Cat., 346, 1798 (2004); Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Formula:C15H18OColor and Shape:White To GreyMolecular weight:214.34-Acetaminophen-d3 Sulfate
CAS:Controlled Product<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formula:C82H3H6NO5SColor and Shape:White To Off-WhiteMolecular weight:234.241-(2,3-Dimethylphenyl)ethyl Chloride
CAS:Controlled Product<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formula:C10H13ClColor and Shape:Clear Colourless To Dark BrownMolecular weight:168.66(R)-Apomorphine b-D-Glucuronide
Controlled ProductFormula:C23H25NO8Color and Shape:WhiteMolecular weight:443.452,2',5'-Trichloroacetophenone
CAS:Controlled Product<p>Applications 2,2',5'-Trichloroacetophenone is a useful research chemical for organic synthesis and other chemical processes.<br>References Xu, L., et al.: Chem. Res. Chin. Univ., 24, 299 (2008); Song, W., et al.: MedChemComm, 7, 1441 (2016)<br></p>Formula:C8H5Cl3OColor and Shape:NeatMolecular weight:223.48Niflumic Acid
CAS:Controlled Product<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formula:C13H9F3N2O2Color and Shape:Light YellowMolecular weight:282.223-Methylbenzophenone
CAS:<p>Applications 3-Methylbenzophenone (cas# 643-65-2) is a useful research chemical.<br></p>Formula:C14H12OColor and Shape:NeatMolecular weight:196.244-Hydroxydiphenylamine
CAS:Controlled ProductFormula:C12H11NOColor and Shape:NeatMolecular weight:185.228-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Formula:C10H9NColor and Shape:Light Yellow LiquidMolecular weight:143.185rac-Ibuprofen Amide
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Formula:C13H19NOColor and Shape:WhiteMolecular weight:205.30Acetanilide (Acetylaniline)
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Formula:C8H9NOColor and Shape:White To Light BrownMolecular weight:135.16(S)-Ketorolac
CAS:Controlled Product<p>Applications (S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Formula:C15H13NO3Color and Shape:NeatMolecular weight:255.271-(4-(Phenylethynyl)phenyl)ethan-1-one
CAS:Purity:95%Color and Shape:SolidMolecular weight:220.27099613-Hydroxy Medetomidine
CAS:Controlled Product<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Formula:C13H16N2OColor and Shape:NeatMolecular weight:216.28Ketoprofen 1,4-Sorbitan Ester
Controlled Product<p>Applications Ketoprofen 1,4-Sorbitan Ester is a derivative of Ketoprofen (K200800), an anti-inflammatory; analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Formula:C22H24O7Color and Shape:Off-WhiteMolecular weight:400.42Hydroxy Carisoprodol (mixture of diastereomers)
CAS:Controlled Product<p>Applications Hydroxy Carisoprodol is the metabolite of Carisoprodol (C183580) in equine urine and serum.<br>References Kintz, P., et al.: J. Anal. Toxicol., 17, 408 (1993), Olsen, H., et al.: Ther. Drug Monit., 16, 337 (1994), Reeves, R., et al.: J. Addict. Diseas., 18, 51 (1999),<br></p>Formula:C12H24N2O5Color and Shape:NeatMolecular weight:276.33(-)-(3S)-3-Hydroxy Quinine
CAS:Controlled ProductFormula:C20H24N2O3Color and Shape:NeatMolecular weight:340.42Metaxalone-d6
CAS:Controlled Product<p>Applications It is a muscle relaxant used to relax muscles and relieve pain.<br></p>Formula:C122H6H9NO3Color and Shape:NeatMolecular weight:227.29Bornyl Acetate (Mixture of Diastereomers)
CAS:<p>Applications Bornyl Acetate (Mixture of Diastereomers) is a monoterpene ester, and also the main, natural constituent of valerian root oil. Bornyl acetate also has analgesic and anti-inflammatory properties.<br>References Buchbauer, G., et al.: Die Pharm., 47, 620 (1992); Oh, H., et al.: Appl. Micro., 15, 777 (1967); Wu, X., et al.: J. Chinese Med. Mat., 27, 438 (2004)<br></p>Formula:C12H20O2Color and Shape:NeatMolecular weight:196.29Acemetacin
CAS:Controlled Product<p>Applications Acemetacin is a non-steroidal anti-inflammatory agent and used to treat rheumatic disease and other musculoskeletal disorders (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Jacobi, H. and Dell, H. D.: Arzneimittelforschung 30, 1398 (1980) (2) Moore, R. A., et al.: Cochrane Database Syst Rev. 8,CD007589 (2009)<br></p>Formula:C21H18ClNO6Color and Shape:YellowMolecular weight:415.82rac Ketoprofen Amide
CAS:Controlled Product<p>Applications An amide of Ketoprofen (K200800) with anti-inflammatory properties.<br>References Spickett, R.G.W. et al.: Eur. J. Med. Chem., 11, 7 (1976); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Formula:C16H15NO2Color and Shape:WhiteMolecular weight:253.304'-Isobutylacetophenone
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formula:C12H16OColor and Shape:Colourless To Light YellowMolecular weight:176.25S-Methyl-d3-thioacetaminophen
CAS:Controlled Product<p>Applications S-Methyl-d3-thioacetaminophen is deuterium labeled S-Methyl-3-thioacetaminophen (M330610), a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C92H3H8NO2SColor and Shape:NeatMolecular weight:200.27rac-4’-Methyl Ketoprofen
CAS:<p>Impurity Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A<br>Applications rac-4’-Methyl Ketoprofen (Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A) is an impurity of Ketoprofen (K200800).<br>References Pietta, P. et al.: J. Chrom., 387, 525 (1987); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Formula:C17H16O3Color and Shape:BeigeMolecular weight:268.31rac Ketoprofen-d3
CAS:Controlled Product<p>Applications rac Ketoprofen-d3 is the labeled analogue of rac Ketoprofen (K200800), an anti-inflammatory; analgesic. rac Ketoprofen-d3 has been used in the preparation of labeled human drug metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990); Poraj-Kobielska, M., et. al.: J. Labelled Compd. Rad., 56, 513 (2013)<br></p>Formula:C162H3H11O3Color and Shape:NeatMolecular weight:257.30TEMPO
CAS:Controlled Product<p>Applications TEMPO is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. TEMPO can also be used as a mediator in free radical polymerization.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seaton, T.A. et al.: Brain Res., 777, 110 (1997); Tanielyan, S.K. et al.: Top. Catal., 55, 556 (2012); Wolinska-Grabczyk, A. et al.: Polymer, 46, 2461 (2005); Keoshkerian, B. et al.: Polym. Prep., 35, 675 (1994);<br></p>Formula:C9H18NOColor and Shape:NeatMolecular weight:156.25rac-Naproxen
CAS:<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formula:C14H14O3Color and Shape:NeatMolecular weight:230.26rac Ketorolac Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Moisture Sensitive, Light Sensitive<br>Applications A metabolite of Ketorolac.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Brocks, D., et al.: Clin. Pharmacokinet., 23, 415 (1992), Vakily, M., et al.: Pharm. Res., 12, 1652 (1995), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Formula:C21H21NO9Color and Shape:NeatMolecular weight:431.39Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C10H11NO3Color and Shape:White To Off-WhiteMolecular weight:193.20Phenacetin
CAS:Controlled Product<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Formula:C10H13NO2Color and Shape:WhiteMolecular weight:179.22Phenacetin-d3
CAS:Controlled Product<p>Applications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)<br></p>Formula:C10H10D3NO2Color and Shape:NeatMolecular weight:182.232-Chloronicotinic Acid
CAS:Controlled Product<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Formula:C6H4ClNO2Color and Shape:NeatMolecular weight:157.553'-Chloroacetophenone
CAS:Purity:97.0%Color and Shape:Liquid, ClearMolecular weight:154.58999633789062rac Ketoprofen PEG 400 Ester
Controlled Product<p>Applications rac Ketoprofen PEG 400 Ester is an impurity of rac Ketoprofen (K200800) which is anti-inflammatory.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C18H18O4Color and Shape:Colourless To Light YellowMolecular weight:n/a
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