Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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Metronidazole
CAS:<p>Applications Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C6H9N3O3Color and Shape:White To Off-WhiteMolecular weight:171.15Rufinamide
CAS:<p>Applications Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:White To Off-WhiteMolecular weight:238.194-Methoxy-2-nitroaniline(2-Nitro-p-anisidine)
CAS:Controlled Product<p>Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)<br></p>Formula:C7H8N2O3Color and Shape:NeatMolecular weight:168.152,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C22H27N5O2Color and Shape:NeatMolecular weight:393.48Atropine Sulfate Monohydrate
CAS:Controlled Product<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColor and Shape:White To Light YellowMolecular weight:694.83Iso Letrozole
CAS:<p>Impurity Letrozole EP Impurity A; Letrozole USP Related Compound A<br>Applications Isoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.<br>References Fleming, F.F., et al.: J. Med. Chem., 53, 7902 (2010),<br></p>Formula:C17H11N5Color and Shape:NeatMolecular weight:285.30Glycopyrrolate Bromide-d3 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled analogue of Glycopyrrolate Bromide, a novel pharmaceutical compound based on PDE IV inhibitors. Glycopyrrolate Bromide is used in the treatment of respiratory complaints.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995);<br></p>Formula:C19H25D3NO3·BrColor and Shape:NeatMolecular weight:401.354-Descarboxamido Rufinamide 4-Methyl Ester
CAS:Controlled Product<p>Applications 4-Descarboxamido Rufinamide 4-Methyl Ester is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C11H9F2N3O2Color and Shape:NeatMolecular weight:253.20Temazepam-13C,d3
CAS:Controlled Product<p>Applications Temazepam-13C,d3 is labelled Temazepam (T017200) which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C1513CH10D3ClN2O2Color and Shape:NeatMolecular weight:304.75Imidacloprid-3-hydroxy
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-Chloro-5-[[4,5-dihydro-2-(nitroamino)-1H-imidazol-1-yl]methyl]-3-pyridinol is an analog of Imidacloprid (I274990) which is an active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C9H10ClN5O3Color and Shape:White To Light BeigeMolecular weight:271.66Oxcarbazepine
CAS:<p>Applications A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989); Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001);<br></p>Formula:C15H12N2O2Color and Shape:Light YellowMolecular weight:252.27(S)-N-Methyl Pregabalin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The major metabolite of Pregabalin.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C9H19NO2Color and Shape:NeatMolecular weight:173.252,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.26Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Controlled Product<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.57(S)-Lansoprazole
CAS:Controlled Product<p>Applications The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:NeatMolecular weight:369.365-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O4SColor and Shape:NeatMolecular weight:361.42Oxybutynin Chloride
CAS:Controlled Product<p>Applications An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22H31NO3·ClHColor and Shape:White To Off-WhiteMolecular weight:393.95Ravuconazole-d4
CAS:Controlled Product<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>Formula:C22H13D4F2N5OSColor and Shape:NeatMolecular weight:441.49(R)-Rabeprazole Sodium Salt
CAS:Controlled Product<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Formula:C18H20N3NaO3SColor and Shape:NeatMolecular weight:381.422-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine
CAS:Controlled Product<p>Applications An Intermediate for the synthesis of Midazolam.<br>References Walser, A., J. Org. Chem., 43, 936 (1978).<br></p>Formula:C16H15ClFN3Color and Shape:NeatMolecular weight:303.765-(S-Methyl) Albendazole
CAS:<p>Impurity Albendazole EP Impurity F<br>Applications 5-(S-Methyl) Albendazole is a metabolite of Albendazole (A511610). Albendazole EP Impurity F<br>References Gyurik, R.J., et al.: Drug Metab. Dispos., 9, 503 (1981),<br></p>Formula:C10H11N3O2SColor and Shape:NeatMolecular weight:237.28(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide
CAS:Controlled Product<p>Impurity Tiotropium bromide EP impurity C<br>Applications (1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C19H22NO3S2·BrColor and Shape:NeatMolecular weight:456.42Mebendazole-d8
CAS:Controlled Product<p>Applications Labelled Mebendazole (M200500). Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Formula:C162H3H10N3O3Color and Shape:NeatMolecular weight:298.312-Mercapto-4,5,6,7-d4-benzimidazole
CAS:Controlled ProductFormula:C72H4H2N2SColor and Shape:NeatMolecular weight:154.23Tebuconazole-d9
CAS:Controlled Product<p>Applications Isotope labelled Tebuconazole (T013000), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-91 2. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Formula:C16H13D9ClN3OColor and Shape:White To Light YellowMolecular weight:316.87Thiabendazole-d4 (Major)
CAS:Controlled ProductFormula:C10D4H3N3SColor and Shape:Off WhiteMolecular weight:205.274,4'-Dicyanobenzophenone
CAS:<p>Applications Letrozole intermediate.<br>References Gomez, R., et al.: J. Mat. Chem., 17, 4274 (2007),<br></p>Formula:C15H8N2OColor and Shape:Light BrownMolecular weight:232.24Imidacloprid-d4
CAS:Controlled Product<p>Applications Imidacloprid-d4 is labelled Imidacloprid (I274990) which is a neonicotinoid, the active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C92H4H6ClN5O2Color and Shape:WhiteMolecular weight:259.69Oxazepam-d5
CAS:Controlled Product<p>Applications Labelled Oxazepam. Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepinemodulatory site.Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Formula:C152H5H6ClN2O2Color and Shape:Off-WhiteMolecular weight:291.74Tert-Butyl 6-(benzyloxy)-4-fluoro-1H-indazole-1-carboxylate
CAS:Purity:95.0%Molecular weight:342.36999511718752-Methyl-5-nitroimidazole
CAS:<p>Impurity Tinidazole EP Impurity A/ Metronidazole EP Impurity A<br>Applications 2-Methyl-5-nitroimidazole (Tinidazole EP Impurity A) is a Floconazole impurity.<br>References Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), Kumar, L., et al.: Eur. J. Med. Chem., 45, 817 (2010),<br></p>Formula:C4H5N3O2Color and Shape:Light YellowMolecular weight:127.105-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one
CAS:Controlled Product<p>Applications This compound contains a benzimidazolone moiety which has been seen to inhibit p38 MAP kinase , a crucial protein in the activation of biological factors related to psoriasis, rheumatoid arthritis and other inflammatory diseases.<br>References Hammach, A. et al.: Bioorg. Med. Chem. Lett., 16, 6316 (2006);<br></p>Formula:C14H10N2O2Color and Shape:NeatMolecular weight:238.24Triazolam N-Oxide
CAS:Controlled Product<p>Applications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.21Lifitegrast
CAS:Controlled Product<p>Applications Lifitegrast is used for the treatment of signs and symptons of dry eye diseases. It also Inhibites corneal inflammation that is capable of causing pains, blurred vision and ocular discomfort in sufferer.<br>References Holland, E. J., et al.: Curr. Med. Res. Opin., 32, 1759 (2016); Sun, Y., et al.: J. Ocul. Pharmacol. Ther., 29, 395 (2013);<br></p>Formula:C29H24Cl2N2O7SColor and Shape:White To Off-WhiteMolecular weight:615.48110-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Controlled Product<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Formula:C17H14N2O3Color and Shape:NeatMolecular weight:294.30NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Formula:C10H15NOColor and Shape:WhiteMolecular weight:165.23Rupatadine-d4 Fumarate
CAS:Controlled Product<p>Applications Labelled Rupatadine (R701650). Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.<br>References Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997), Guadano, E.M., et al.: Allergy, 59, 766 (2004),<br></p>Formula:C30H26D4ClN3O4Color and Shape:NeatMolecular weight:536.058-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide (Midazolam 5-Oxide)
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:NeatMolecular weight:341.77Nocodazole
CAS:<p>M05733 - Nocodazole</p>Formula:C14H11N3O3SPurity:98%Color and Shape:Solid, Beige powderMolecular weight:301.32000732421875N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Controlled Product<p>Applications Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H21N3O3SColor and Shape:Off White SolidMolecular weight:359.44Rufinamide-5-Carboxamide
CAS:Controlled Product<p>Applications Rufinamide-5-Carboxamide is an impurity of Rufinamide (R701550) which is an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:NeatMolecular weight:238.191’-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512 (2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449 (2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463 (2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.77Carbendazim
CAS:Controlled Product<p>Impurity Albendazole EP Impurity E<br>Applications Carbendazim (Albendazole EP Impurity E) is a fungicide and an impurity of Albendazole.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, Z., et al.: J. Agric. Food Chem., 44, 3374 (1996), Lewis, D., et al.: Xenobiotica, 28, 235 (1998), Hodgson, E., et al.: J. Biochem. Mol. Toxicol., 21, 182 (2007),<br></p>Formula:C9H9N3O2Color and Shape:WhiteMolecular weight:191.195-Hydroxy Lansoprazole Potassium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor.<br>References Uno, T., et al.: J. Clin. Pharmacol., 45, 690 (2005), Saito, M., et al.: Brit. J. Clin. Pharmacol., 59, 302 (2005),<br></p>Formula:C16H13F3N3O3S·KColor and Shape:NeatMolecular weight:423.452,3,5-Trimethylpyridine N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Off-White To Light BrownMolecular weight:137.18Letrozole-d4 (major)
CAS:Controlled ProductFormula:C17D4H7N5Color and Shape:Yellowish SolidMolecular weight:289.337-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide
CAS:Controlled Product<p>Applications 7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Laviana, L., et al.: J. Pharma. Biomed. Anal., 32, 167 (2003); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C16H11ClFN3O3Color and Shape:NeatMolecular weight:347.732,4-Dichlorobenzyl Chloride
CAS:Controlled Product<p>Applications Reagent used in the addition of dichlorobenzene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marchand, P., et al.: Bioorg. Med. Chem., 17, 6715 (2009); Singh, J., et al.: J. Med. Chem., 53, 18 (2010);<br></p>Formula:C7H5Cl3Color and Shape:NeatMolecular weight:195.472,4,5-Triphenyl-1H-imidazole
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:296.37298583984375Desnitro-imidacloprid Hydrochloride
CAS:Controlled ProductFormula:C9H11ClN4·ClHColor and Shape:Light Orange GreyMolecular weight:247.12Dihydro Donepezil(Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Donepezil Dihydro Impurity<br>Applications A potential metabolite of Donepezil.<br>References Dooley, M., et al.: Drugs Aging, 16, 199 (2000), Gotti, R., et al.: J. Pharm. Biomed. Anal., 24, 863 (2001), Gotti, R., et al.: Anal. Bioanal. Chem., 377, 875 (2003),<br></p>Formula:C24H31NO3Color and Shape:NeatMolecular weight:381.512,3-Diphenyl-5-(thiophen-2-yl)-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:340.8299865722656Scopine Methobromide
CAS:<p>Impurity Tiotropium EP Impurity G<br>Applications Scopine Methobromide (Tiotropium EP Impurity G) is an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)<br></p>Formula:C9H16NO2·BrColor and Shape:Off-WhiteMolecular weight:250.13Scopine Di(2-thienylglycolate)
CAS:<p>Impurity Tiotropium EP Impurity B<br>Applications Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.<br>References Buchwald, P., et al.: Pharmazie., 55, S210 (2000),<br></p>Formula:C18H19NO4S2Color and Shape:NeatMolecular weight:377.484-Nitro-1H-imidazole
CAS:Controlled Product<p>Applications Metronidazole (M338880) derivative, an antibacterial in the treatment of rosacea and inflammatory bowel disease.<br>References Khan, K. et al.; Am. J. Gastroenterol. 106, 661 (2011)<br></p>Formula:C3H3N3O2Color and Shape:NeatMolecular weight:113.07Carbamazepine-d8(Major)
CAS:Controlled Product<p>Applications Labelled Carbamazepine (C175840). Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formula:C15H4D8N2OColor and Shape:NeatMolecular weight:244.32Secnidazole-d6
CAS:Controlled Product<p>Applications Labelled Secnidazole (S225000). Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H5D6N3O3Color and Shape:NeatMolecular weight:191.22Ornidazole Isomer (Impurity)
CAS:Controlled Product<p>Applications An isomeric impurity of Ornidazole (0688500), which maintains anti-infective properties.<br>References Hoffer, M., et al.: J. Med. Chem., 17, 1019 (1974);<br></p>Formula:C7H10ClN3O3Color and Shape:NeatMolecular weight:219.635-(4-chlorophenyl)-1-(2-methoxyphenyl)-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:316.79998779296875N-Desalkyl Itraconazole
CAS:Controlled Product<p>Applications N-Desalkyl Itraconazole is a derivative of itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C31H30Cl2N8O4Color and Shape:NeatMolecular weight:649.53Methyl Methanethiosulfonate
CAS:Controlled ProductFormula:C2H6O2S2Color and Shape:NeatMolecular weight:126.20Midazolam-d6
CAS:Controlled Product<p>Applications Labelled Midazolam (M343000). Anesthetic; anticonvulsant; sedative; hypnotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000),<br></p>Formula:C18D6H7ClFN3Color and Shape:NeatMolecular weight:331.80Triclabendazole Sulfone-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfone-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14D3H6Cl3N2O3SColor and Shape:NeatMolecular weight:394.68Temazepam Acetate
CAS:Controlled Product<p>Applications Temazepam Acetate is an impurity of temazepam (T017200), which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C18H15ClN2O3Color and Shape:White To Off-WhiteMolecular weight:342.785-Methyl Zolpidem
CAS:Controlled Product<p>Applications An impurity of Zolpidem (Z650000).<br></p>Formula:C19H21N3OColor and Shape:NeatMolecular weight:307.39Secnidazole-d3
CAS:Controlled Product<p>Applications Labelled Secnidazole (S225000). Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H8D3N3O3Color and Shape:White To Off-WhiteMolecular weight:188.2Clidinium Bromide
CAS:Controlled Product<p>Applications An anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C22H26NO3·BrColor and Shape:White SolidMolecular weight:432.353-Bromo Zolpidem
Controlled ProductFormula:C19H20BrN3OColor and Shape:White To Off-WhiteMolecular weight:386.29O-Acetyl Scopolamine Hydrobromide
CAS:Controlled Product<p>Applications Scopolamine Hydrobromide (S200000) derivative. An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C19H24BrNO5Color and Shape:NeatMolecular weight:426.3Isavuconazole-d4
CAS:Controlled Product<p>Applications Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.<br>References Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)<br></p>Formula:C22H13D4F2N5OSColor and Shape:White To YellowMolecular weight:441.49(S)-Pregabalin Lactam
CAS:<p>Impurity Pregabalin EP impurity A<br>Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:WhiteMolecular weight:141.213,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.205-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole
CAS:Controlled Product<p>Applications 5-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole is an impurity of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C16H17N3O2Color and Shape:NeatMolecular weight:283.334-(2-Methylpropyl)piperidine-2,6-dione
CAS:Formula:C9H15NO2Color and Shape:White SolidMolecular weight:169.22Clotrimazole
CAS:<p>Applications Clotrimazole is an antifungal agent.<br>References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.84Ornidazole
CAS:<p>Applications Anti-infective.<br>References Grunberg, E, et al.: Proc. Soc. Exp. Biol. Med., 133, 490 (1970), Hoffer, M., et al.: J. Med. Chem., 17, 1019 (1974), Schwartz, D.E., et al.: Chemotherapy, 22, 19 (1976),<br></p>Formula:C7H10ClN3O3Color and Shape:Off-WhiteMolecular weight:219.635,6-Dihydro Midazolam
CAS:Controlled Product<p>Impurity Midazolam EP Impurity A<br>Applications Midazolam (M343000) analog useful as anticonvulsant, muscle relaxant.<br>References Ramig, K., et al.: Tetrahedron Lett., 33, 6279 (1992),<br></p>Formula:C18H15ClFN3Color and Shape:White To Off-WhiteMolecular weight:327.78Lamotrigine-13C3,d3, Major
CAS:Controlled Product<p>Applications An isotopically labelled Lamotrigine (L173250), an anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C3C62H3H4Cl2N5Color and Shape:Off-White To Light YellowMolecular weight:262.092-cyclopropyl-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:158.203994750976562-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:Light YellowMolecular weight:256.09Letrozole
CAS:<p>Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C17H11N5Color and Shape:YellowMolecular weight:285.30Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.21Hydroxy Metronidazole-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C62H4H5N3O4Color and Shape:Off-WhiteMolecular weight:191.18Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71Omeprazole Sulfone
CAS:<p>Impurity USP Omeprazole Related Compound A<br>Applications A metabolite of Omeprazole.<br></p>Formula:C17H19N3O4SColor and Shape:White To Light BrownMolecular weight:361.42(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.30Dibenzazepine-10,11-dione
CAS:Controlled Product<p>Applications Dibenzazepine-10,11-dione is an impurity of Oxcarbazepine (O869250). Dibenzazepine-10,11-dione is used as a reagent in the preparation of bifunctional dipolar electroluminescent template for optoelectronic applications.<br>References Chen, C.-T. et al.: Chem. Comm., 31, 3980 (2005); Heckendorn, R. et al.: Helv, Chim. Acta, 70, 1955 (1987);<br></p>Formula:C14H9NO2Color and Shape:NeatMolecular weight:223.23Oxybutynin-d11 Chloride
CAS:Controlled Product<p>Applications An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22D11H20NO3·ClHColor and Shape:NeatMolecular weight:405.02N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxybenzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:302.39999389648444-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.77cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate
CAS:<p>Impurity Itraconazole Impurity 16<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989);<br></p>Formula:C14H15Cl2N3O5SColor and Shape:NeatMolecular weight:408.257(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
CAS:Controlled Product<p>Applications (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-Butanediol (cas# 133775-25-4) is a useful research chemical.<br></p>Formula:C12H13F2N3O2Color and Shape:NeatMolecular weight:269.255-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:329.4200134277344
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