Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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4-Methylenepiperidine Hydrochloride
CAS:Controlled Product<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>Formula:C6H11N•(HCl)Color and Shape:NeatMolecular weight:97.163646Iso Letrozole
CAS:<p>Impurity Letrozole EP Impurity A; Letrozole USP Related Compound A<br>Applications Isoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.<br>References Fleming, F.F., et al.: J. Med. Chem., 53, 7902 (2010),<br></p>Formula:C17H11N5Color and Shape:NeatMolecular weight:285.30Clidinium Bromide
CAS:Controlled Product<p>Applications An anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C22H26NO3·BrColor and Shape:White SolidMolecular weight:432.35N-[3-(1H-imidazol-1-yl)propyl]-4,6-dimethyl-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:286.39999389648444-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazole-2-carbaldehyde
CAS:Purity:99.0%Molecular weight:304.312988281253-Bromo Zolpidem
Controlled ProductFormula:C19H20BrN3OColor and Shape:White To Off-WhiteMolecular weight:386.295-(2-Fluorophenyl)oxazole-4-carboxylic acid
CAS:Formula:C10H6FNO3Purity:95.0%Color and Shape:SolidMolecular weight:207.165-Methyl-2-phenoxypyridine
CAS:Controlled ProductFormula:C12H11NOColor and Shape:NeatMolecular weight:185.23Albendazole Sulfone
CAS:<p>Impurity Albendazole EP Impurity C / Albendazole Sulfone<br>Applications A metabolite of Albendazole, an anthelmintic. Albendazole EP Impurity C<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O4SColor and Shape:BeigeMolecular weight:297.336-(1-METHYL-1H-PYRAZOL-4-YL)-3-((2-METHYL-2H-INDAZOL-5-YL)THIO)-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE
CAS:Purity:95.0%Molecular weight:362.4200134277344Miconazole Impurity H
CAS:Controlled Product<p>Impurity Miconazole EP Impurity H<br>Applications Miconazole Impurity H (Miconazole EP Impurity H), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H16Cl2N2OColor and Shape:NeatMolecular weight:347.241-(TETRAHYDRO-2H-PYRAN-2-YL)-1H-INDAZOLE-6-CARBOXYLIC ACID
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:246.26600646972656(-)-Donepezil
CAS:Controlled Product<p>Applications (-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.<br>References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993), Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994)<br></p>Formula:C24H29NO3Color and Shape:NeatMolecular weight:379.49O-Acetyl Scopolamine Hydrobromide
CAS:Controlled Product<p>Applications Scopolamine Hydrobromide (S200000) derivative. An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C19H24BrNO5Color and Shape:NeatMolecular weight:426.3Itraconazole N,N-Dioxide
Controlled Product<p>Stability Hygroscopic<br>Applications Itraconazole N,N-Dioxide is a derivative of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C35H38Cl2N8O6Color and Shape:NeatMolecular weight:737.633-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid
CAS:Formula:C9H17NO3Color and Shape:NeatMolecular weight:187.243-(4-((1H-IMIDAZOL-1-YL)METHYL)PHENYL)-N-(TERT-BUTYL)THIOPHENE-2-SULFONAMIDE
CAS:Purity:95.0%Molecular weight:375.510009765625Tetrabutylammonium Bromide
CAS:Controlled Product<p>Applications Tetrabutylammonium Bromide is used in the synthesis of polymer solar cells. Also used in the synthesis of single component green-light emitting electrochemical cells.<br>References Yun, H. et al.: Chem. A Eur. J., 19, 13242 (2013); Sun, M. et al.: J. Disp. Tech., 9, 476 (2013);<br></p>Formula:C16H36N·BrColor and Shape:White To Off-WhiteMolecular weight:322.372-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Purity:95.00%Molecular weight:399.3699951171875Isavuconazole-d4
CAS:Controlled Product<p>Applications Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.<br>References Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)<br></p>Formula:C22H13D4F2N5OSColor and Shape:White To YellowMolecular weight:441.492-Chloro-5-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)phenol
CAS:Purity:95.0%Molecular weight:347.79998779296875TRAM-34
CAS:Controlled Product<p>Applications TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.<br>References Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.84a-Descyclohexyl-a-phenyl Oxybutynin
CAS:Controlled Product<p>Impurity Oxybutynin EP Impurity B<br>Applications α-Descyclohexyl-α-phenyl Oxybutynin (Oxybutynin EP Impurity B) is an Oxybutynin impurity; 4-(dialkylamino)-2-butynyl benzilates as parasympatholytic substances.<br>References Dahlbom, R., et al.: Acta Chem. Scand., 17, 2354 (1963),<br></p>Formula:C22H25NO3Color and Shape:NeatMolecular weight:351.44Fenbendazole-d3
CAS:Controlled Product<p>Applications Labelled Fenbendazole (F246750). An anthelmintic (Nematodes).<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C15H10D3N3O2SColor and Shape:Off White SolidMolecular weight:302.37Thiabendazole-d4 (Major)
CAS:Controlled ProductFormula:C10D4H3N3SColor and Shape:Off WhiteMolecular weight:205.27(1-Phenyl-1H -tetrazol-5-ylsulfanyl)-acetic acid
CAS:Formula:C9H8N4O2SPurity:95+%Color and Shape:SolidMolecular weight:236.25Carbamazepine 10,11-Epoxide
CAS:<p>Applications A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H12N2O2Purity:>97% by HPLCColor and Shape:NeatMolecular weight:252.272-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
CAS:Purity:97.0%Color and Shape:Solid, White - Almost white powderMolecular weight:428.54000854492192-Imidazol-1-yl-benzylamine
CAS:Formula:C10H11N3Purity:95.0%Color and Shape:AmorphousMolecular weight:173.2192-(benzylthio)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:240.32000732421875(S)-Oxybutynin Chloride
CAS:Controlled Product<p>Applications The optically active inhibitor of proliferation and suppresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22H31NO3·ClHColor and Shape:NeatMolecular weight:393.9510,11-Dihydro-10-hydroxy Carbamazepine-D4 (Major)
CAS:Controlled ProductFormula:C152H4H10N2O2Color and Shape:BrownMolecular weight:258.315-Hydroxy Thiabendazole-13C2,15N
CAS:Controlled Product<p>Applications Labelled 5-Hydroxy Thiabendazole (H961200). 5-Hydroxy Thiabendazole is the major metabolite of Thiabendazole (T344150).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujitani, T., et al.: Food Chem. Toxicol., 29, 265 (1991), Mizutani, T., et al.: Chem. Res. Toxicol., 6, 174 (1993), Dalvie, D., et al.: J. Agric. Food Chem., 42, 2964 (2006),<br></p>Formula:C813C2H7N215NOSColor and Shape:NeatMolecular weight:220.231-Benzyl-3-hydroxy-1H-indazole
CAS:Purity:95.0%Color and Shape:Solid, White to slightly pale reddish yellow powderMolecular weight:224.263000488281253,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.20
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