Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8902 products of "Purines and Pyrimidine Derivatives"
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Tenofovir Disoproxil Isopropoxycarbonyl
CAS:<p>Stability Hygroscopic<br>Applications Tenofovir Disoproxil derivative as antiviral and antitumor agent.<br></p>Formula:C23H36N5O12PColor and Shape:White SolidMolecular weight:605.53Acetaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Hygroscopic<br>Applications Acetaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic alldehyde found in mainstream cigarette smoke. Dyes and metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zwiener, C. et al.: Anal. Bioanal. Chem., 372, 615 (2002); Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Formula:C8H8N4O4Color and Shape:YellowMolecular weight:224.17Phenylhydrazine
CAS:Controlled Product<p>Applications An aryl hydrazine used in the preparation of various dyes and pharmaceutical compounds. It is used in the investigation of oligosaccharides as well as the structure of photosystem II.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lattova, E. et al.: Meth. Mol. Biol., 534, 65 (2009); Anderson, L.B. et al.: J. Biol. Chem., 275, 4920 (2000);<br></p>Formula:C6H8N2Color and Shape:Yellowish LiquidMolecular weight:108.14Pemetrexed Sodium Methyl Ester
Controlled Product<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formula:C21H22N5NaO6Color and Shape:NeatMolecular weight:463.4194-(2H-1,3-benzodioxol-5-yl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:319.364013671875Ethyl-S-(+)-Clopidogrel Sulfate
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Ethyl-(S)-(+)-Clopidogrel Sulfate is an analogue of S-(+)-Clopidogrel Hydrogen Sulfate (C587250) which is used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Formula:C17H20ClNO6S2Color and Shape:White To Off-WhiteMolecular weight:433.93Pirimiphos-methyl, 90%
CAS:Controlled Product<p>Applications Pirimiphos-methyl is a phosphorothioate used as an insecticide. Pirimiphos-methyl is commonly used for mosquito control as well as control of greenhouse crop pests and stored-product insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deighton, J. et al.: Mosq. News, 34, 163 (1974); LaHue, D.W.: J. Econ. Entomol., 68, 236 (1975); Antonious, G.F. et al.: J. Entomol. Sci., 30, 191 (1995):<br></p>Formula:C11H20N3O3PSPurity:90%Color and Shape:ColourlessMolecular weight:305.335-cyclopropyl-N-(diaminomethylidene)-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide
CAS:Purity:98%Molecular weight:320.3559875488281Chloromethyl Methyl Carbonate
CAS:Controlled Product<p>Applications A reagent used in the preparation of prodrugs of diacidic nonpeptide angiotensin II antagonist as well as pyrrolothiazole platelet activating factor antagonist.<br>References Aungst, B.J. et al.: Pharmac. Res., 12, 763 (1996); Davidsen, S.K. et al.: J. Med. Chem., 37, 4423 (1994);<br></p>Formula:C3H5ClO3Color and Shape:NeatMolecular weight:124.52Tenofovir Isopropyl Ethyl Diester
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Tenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C18H28N5O10PColor and Shape:NeatMolecular weight:505.42Allopurinol-d2
CAS:Controlled Product<p>Applications Labelled xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978), Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005), Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005),<br></p>Formula:C52H2H2N4OColor and Shape:Light BrownMolecular weight:138.122-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:259.312988281256-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:277.260009765625Methotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H22N8O5Color and Shape:Yellow To Dark YellowMolecular weight:454.448-CYCLOPENTYL-1,3-DIPROPYL-1H-PURINE-2,6(3H,7H)-DIONE
CAS:Purity:95%Molecular weight:304.3940124511719Urea-15N2
CAS:Controlled Product<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>Formula:CH415N2OColor and Shape:Off White SolidMolecular weight:62.04(S)-Tenofovir Disoproxil Fumarate
CAS:Controlled Product<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C19H30N5O10P·C4H4O4Color and Shape:White SolidMolecular weight:635.52Methotrexate-Cadaverine-Biotin Conjugate
Controlled Product<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C35H48N12O6SPurity:>85%Color and Shape:NeatMolecular weight:764.94-[6-(4-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Purity:95.0%Molecular weight:278.31500244140625(6-Benzhydryloxycarbonylamino-purin-9-yl)-acetic acid
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:403.398010253906254-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester, 100 mg
CAS:<p>Impurity Oseltamivir EP Impurity D<br>Applications 4-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester (Oseltamivir EP Impurity D) is an impurity in the antiviral drug Oseltamivir (O700100).<br></p>Formula:C11N13NO4Color and Shape:NeatMolecular weight:223.235-Azido Oseltamivir
CAS:Controlled Product<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Kim, C., et al.: J. Med. Chem., 41, 2451 (1998), Carbain, B., et al.: Chem. Med. Chem., 4, 335 (2009),<br></p>Formula:C16H26N4O4Color and Shape:NeatMolecular weight:338.40Memantine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Formula:C12H21N·ClHColor and Shape:White To Off-WhiteMolecular weight:215.76Tenofovir
CAS:<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formula:C9H14N5O4PColor and Shape:White To Off-WhiteMolecular weight:287.21(S)-5-(1,3-Bis(tert-butoxycarbonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoic acid
CAS:Formula:C21H38N4O8Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:474.555N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Formula:C15H19N3O2Color and Shape:NeatMolecular weight:273.335-Nitro Nicotinic Acid
CAS:Controlled Product<p>Applications An intermediate in the synthesis of nicotinamide with potential anticoccidial activity.<br>References Morisawa, Y. et al.: J. Med. Chem., 20, 129 (1977);<br></p>Formula:C6H4N2O4Color and Shape:NeatMolecular weight:168.11Ondansetron-d3
CAS:Controlled Product<p>Applications Ondansetron-d3 is a labeled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Formula:C18H16D3N3OColor and Shape:NeatMolecular weight:296.386-Methyl Nicotinic Acid
CAS:Controlled Product<p>Applications A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.<br>References Ensign, J., et al.: Biol. Chem., 239, 2285 (1964), Houghton, C., et al.: Biochem. J., 130, 879 (1972),<br></p>Formula:C7H7NO2Color and Shape:NeatMolecular weight:137.141-Methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1-oxide (Imatinib Impurity)
CAS:Purity:98%Molecular weight:509.614Memantine Lactose Adduct
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A lactose adduct of Memantine (M218000). Intermediate in the synthesis of reducing carbohydrate Adamantane amines for use in treating Gram positive or Gram negative bacteria infections.<br>References Kustimur, et al.: Chinese Med. J., 116, 633 (2003),<br></p>Formula:C24H41NO10Color and Shape:NeatMolecular weight:503.586-Mercaptopurine Monohydrate
CAS:Controlled Product<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Formula:C5H4N4S·H2OColor and Shape:YellowMolecular weight:170.192-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Formula:C10H13N5O4S·x(H2O)Color and Shape:Light Yellow PowderMolecular weight:299.314-(4,6-Dimethoxypyrimidin-2-yl)benzoic acid
CAS:Formula:C13H12N2O4Purity:95.0%Color and Shape:SolidMolecular weight:260.2491-((2R,3R,4S,5S)-3,5-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)PYRIMIDINE-2,4(1H,3H)-DIONE
Purity:90.0%Molecular weight:264.18499755859375Nicotinamide-d4 N-Oxide (d4 Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Nicotinamide.<br>References Musfeld, C., et al.: J. Pharm. Biomed. Anal., 24, 391 (2001), Sakakibara, Y., et al.: Brain Res., 931, 68 (2002), Zielonka, J., et al.: Chem. Res. Toxicol., 19, 668 (2006), Wieczorkowska, M., et al.: Pharmacol. Rep., 59, 216 (2007),<br></p>Formula:C6H2D4N2O2Color and Shape:NeatMolecular weight:142.15N-Desacetyl 5-Azido Oseltamivir
CAS:Controlled Product<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),<br></p>Formula:C14H24N4O3Color and Shape:NeatMolecular weight:296.37(E)-3-(2-chlorophenyl)-N-(4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)acrylamide
CAS:Purity:98%Molecular weight:414.8599853515625Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor, used for treatment of hyperuricemia and chronic gout.<br>References Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005);<br></p>Formula:C18H21NO4SColor and Shape:NeatMolecular weight:347.436-Mercaptopurine-13C2,15N (major)
CAS:Controlled Product<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naguib, F., et al.: Biochem. Pharmacol., 50, 1685 (1995), Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004).<br></p>Formula:C313C2H4N315NSColor and Shape:NeatMolecular weight:155.163-Nitro-L-tyrosine-d3
CAS:Controlled Product<p>Applications A labelled marker for peroxynitrite. Oxidant and cytotoxic agent.<br>References Sekiguchi, M., et al.: Brain Res., 978, 228 (2003), van den Tweel, E., et al.: J. Neurobiol., 167, 64 (2005), Shirakura, T., et al.: Biol. Pharm. Bull., 28, 1658 (2005),<br></p>Formula:C9D3H7N2O5Color and Shape:NeatMolecular weight:229.2
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