Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Saccharin N-(2-Acetic Acid Isopropyl Ester)(Piroxicam Impurity F)
CAS:Controlled Product<p>Impurity Piroxicam EP Impurity F<br>Applications Piroxicam impurity F.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formula:C12H13NO5SColor and Shape:NeatMolecular weight:283.30a-Desmethyl Anastrozole(>90%)
CAS:Controlled Product<p>Impurity Anastrozole EP Impurity A<br>Applications α-Desmethyl Anastrozole (Anastrozole EP Impurity A) is an impurity of Anastrozole (A637425) (impurity B).<br></p>Formula:C16H17N5Purity:>90%Color and Shape:ColourlessMolecular weight:279.346-(4-AMINO-4-METHYLPIPERIDIN-1-YL)-3-(2,3-DICHLOROPHENYL)PYRAZIN-2-AMINE
CAS:Purity:95.0%Molecular weight:352.260009765625Ref: 10-F544411
1gTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquireβ-(Cyanoimino)-1-piperidinepropanamide
CAS:Controlled Product<p>Impurity Minoxidil EP Impurity C<br>Applications β-(Cyanoimino)-1-piperidinepropanamide (Minoxidil EP Impurity C) is an impurity in the synthesis of Minoxidil (M345000), used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., et al.: Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992),<br></p>Formula:C9H14N4OColor and Shape:NeatMolecular weight:194.231-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide D-Gluconic Acid
CAS:Controlled ProductFormula:C28H38Cl2N10O5•C6H12O7Color and Shape:NeatMolecular weight:665.57196164-(dimethylamino)-1-neopentylpyridin-1-ium chloride
CAS:Purity:95+%Molecular weight:228.75999450683594Tazarotene-d8
CAS:Controlled Product<p>Applications Labelled Tazarotene (T010050). An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Formula:C21H13D8NO2SColor and Shape:YellowMolecular weight:359.51Moclobemide
CAS:Controlled Product<p>Applications A reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Formula:C13H17ClN2O2Color and Shape:WhiteMolecular weight:268.74Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS:Controlled Product<p>Impurity Levofloxacin USP Related Compound B<br>Applications Levofloxacin intermediate.<br>References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),<br></p>Formula:C13H9F2NO4Color and Shape:NeatMolecular weight:281.211-(2,3-dimethyl-1H-indol-1-yl)-3-(3,5-dimethyl-1H-pyrazol-1-yl)propan-2-ol
CAS:Purity:95.0%Molecular weight:297.40200805664064-((Chloromethyl)sulfonyl)morpholine
CAS:Formula:C5H10ClNO3SPurity:95.0%Color and Shape:No data available.Molecular weight:199.65Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Formula:C15H19N5Purity:99.74%Color and Shape:SolidMolecular weight:269.35Domperidone N-Oxide
CAS:Controlled Product<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Formula:C22H24ClN5O3Color and Shape:White To Off-WhiteMolecular weight:441.91Terbufoxon Sulfoxide
CAS:Controlled Product<p>Applications Terbufoxon Sulfoxide is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food Chem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008); Polgar, L. et al.: J. Chrom. A., 1249, 83 (2012);<br></p>Formula:C9H21O4PS2Color and Shape:NeatMolecular weight:288.36N-Formyl Lenalidomide
CAS:Controlled ProductFormula:C14H13N3O4Color and Shape:NeatMolecular weight:287.277-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
CAS:Purity:98.0%Molecular weight:397.2113897243-(3,5-Dimethyl-pyrazol-1-yl)-benzoic acid
CAS:Formula:C12H12N2O2Purity:95.0%Color and Shape:SolidMolecular weight:216.24Thioridazine-d3 Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Dopamine receptor blocker; parent compound of sulforidazine and mesoridazine. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Formula:C21D3H23N2S2·ClHColor and Shape:NeatMolecular weight:410.052,5-Dimethyl Celecoxib
CAS:Controlled Product<p>Applications A non-cyclooxygenase-2 inhibitor analog of Celecoxib (C251000). The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib.<br>References Deckmann, K. et al.: Biochem. Pharmacol., 80, 1365 (2010); Virrey, J.J. et al.: Mol. Cancer. Therap., 9, 631 (2010); Chen, S. et al.: Leukemia Res., 34, 250 (2010);<br></p>Formula:C18H16F3N3O2SColor and Shape:NeatMolecular weight:395.3987[1,1'-Biphenyl]-4-yl(phenyl)methanol
CAS:Controlled Product<p>Impurity Bifonazole EP Impurity A<br>Applications [1,1'-Biphenyl]-4-yl(phenyl)methanol (Bifonazole EP Impurity A) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C19H16OColor and Shape:NeatMolecular weight:260.33Thioridazine-d3 2-Sulfone
CAS:Controlled Product<p>Applications A labelled metabolite of Thioridazine (THD 2-SO2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Niedzwiecki, D., et al.: J. Pharmacol. Exp. Ther., 250, 126 (1989), Eap, C., et al.: Ther. Drug Monit., 13, 356 (1991), Shah, P., et al.: J. Pharm. Sci., 81, 309 (1992), Eap, C., et al.: J. Pharm. Biomed. Anal., 11, 451 (1993), Blake, B., et al.: Xenobiotica, 25, 337 (1995),<br></p>Formula:C21H23D3N2O2S2Color and Shape:NeatMolecular weight:405.59Decarbonyl Rivaroxaban
CAS:<p>Applications Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C18H20ClN3O4SColor and Shape:White To Off-WhiteMolecular weight:409.89Desmethyl Ofloxacin
CAS:Controlled Product<p>Impurity Ofloxacin EP Impurity E<br>Applications Desmethyl Ofloxacin (Ofloxacin EP Impurity E) is a metabolite of Ofoxacin (O245750), a fluorinated quinolone antibacterial.<br>References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989); Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991); Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994); Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formula:C17H18FN3O4Color and Shape:White To Light BeigeMolecular weight:347.341-Chloro-2-nitrobenzene
CAS:Controlled Product<p>Applications 1-Chloro-2-nitrobenzene is a useful synthetic intermediate. It was used in the synthesis of 1-hydroxybenzotriazole derivatives. Reaction of 1-chloro-2-nitrobenzene with dinitrogen pentoxide in dichloromethane is strongly catalysed by H-Faujasite-720.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fathalla, M., et al.: J. Chem. Soc. Pak., 33, 324 (2011); Claridge, R., et al.: J. Chem. Soc. Perkin Trans. II, 9, 1815, (1999)<br></p>Formula:C6H4ClNO2Color and Shape:NeatMolecular weight:157.551-Benzyl-3-(2,4-dimethylphenyl)-1H-pyrazole-5-carboxylic acid
Purity:95.0%Molecular weight:306.364990234375Marbofloxacin-d8
CAS:Controlled Product<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),<br></p>Formula:C172H8H11FN4O4Color and Shape:NeatMolecular weight:370.40Prochlorperazine Edisylate
CAS:Controlled ProductFormula:C20H24ClN3S·C2H6O6S2Color and Shape:NeatMolecular weight:564.14Desethylene Aripiprazole
CAS:<p>Impurity Aripiprazole Desethylene Impurity<br>Applications Desethylene Aripiprazole is an Aripiprazole derivative. Aripiprazole Desethylene Impurity<br></p>Formula:C21H25Cl2N3O2Color and Shape:NeatMolecular weight:422.35Nitrofurantoin
CAS:Controlled Product<p>Applications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Formula:C8H6N4O5Color and Shape:Light Yellow To YellowMolecular weight:238.16Thiazolylmethyl-4-nitrophenylcarbonate
CAS:Controlled Product<p>Applications Retinovir intermediate.<br>References Randad, R., et al.: Bioorg. Med. Chem. Lett., 4, 1247 (1994), Scholz, et al.: J. Med. Chem., 37, 3079 (1994), Vacca, J., et al.: Bioorg. Med. Chem. Lett., 4, 499 (1994),<br></p>Formula:C11H8N2O5SColor and Shape:Light YellowMolecular weight:280.26(R)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane
CAS:Controlled ProductFormula:C16H17ClOColor and Shape:NeatMolecular weight:260.76Ipragliflozin
CAS:Controlled Product<p>Applications Ipragliflozin is a potent and selective inhibitor of sodium-glucose cotransporter-2 (SGLT2) and can serve as a potential agent for the treatment of type 1 and type 2 diabetes.<br>References Kadokura, T., et al.: Clin. Pharmacokinet., 53, 975 (2014); Kashiwagi, A., et al.: J. Diabetes Investig., 5, 382 (2014); Tahara, A., et al.: J. Pharm. Pharmacol., 66, 975 (2014); Zhang, W., et al.: Clin. Drug Invest., 33, 489 (2013)<br></p>Formula:C21H21FO5SColor and Shape:WhiteMolecular weight:404.45N-Nitroso Iminostilbene
CAS:Controlled Product<p>Applications N-Nitroso Iminostilbene is derived from Iminostilbene (I445000), which is a metabolite of Carbamazepine (CBZ) (C175840).<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001)<br></p>Formula:C14H10N2OColor and Shape:NeatMolecular weight:222.24(R)-(+)-Thalidomide
CAS:Controlled Product<p>Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Formula:C13H10N2O4Color and Shape:NeatMolecular weight:258.234-Bromo-1-(2-fluoro-benzyl)-3-nitro-1H-pyrazole
CAS:Formula:C10H7BrFN3O2Purity:97%Color and Shape:SolidMolecular weight:300.0871,2,4-Triazol-4-amine
CAS:Controlled Product<p>Applications 1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.<br>References Song, Y., et al.: J. Med. Chem., 42, 1151 (1999); Emami, S., et al.: Bioorg. Med. Chem. Lett., 18. 141 (2008)<br></p>Formula:C2H4N4Color and Shape:NeatMolecular weight:84.08Sitagliptin-d4 Phosphate
CAS:Controlled Product<p>Applications A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006).<br></p>Formula:C162H4H11F6N5O·H3O4PColor and Shape:Off-WhiteMolecular weight:509.33Aripiprazole Dimer
CAS:Controlled Product<p>Impurity Aripiprazole EP Impurity G<br>Applications Aripiprazole Dimer is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Aripiprazole EP Impurity G<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998); Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998);<br></p>Formula:C48H56Cl4N6O4Color and Shape:WhiteMolecular weight:922.812-Azahypoxanthine Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-Azahypoxanthine is a major degradation product of Dacarbazine (D101400). 2-Azahypoxanthine is possibly linked with some adverse effects of Dacarbazine (D101400). AHX is a natural product that is produced by fungi that spurs the growth of grass.<br>References Baird, G., et al.: Lancet, 2, 681 (1978), Horton, J., et al.: J. Pharm. Pharmacol., 33, 808 (1981), Shetty, B., et al.: J. Pharm. Biomed. Anal., 10, 675 (1992); Chem. and Eng. News p.7 Oct.1, (2018)<br></p>Formula:C4H2N5NaOColor and Shape:NeatMolecular weight:159.08Ethyl 2-(2-(4-methoxyphenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS:Purity:98%Molecular weight:468.5199890136719N-Formyl Apixaban
CAS:Controlled Product<p>Applications N-Formyl Apixaban is derived from Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C26H25N5O5Color and Shape:NeatMolecular weight:487.51α-(4-Chlorophenyl)-α-propionylacetonitrile
CAS:Controlled Product<p>Applications Pyrimethamine intermediate.<br>References Takayama, K., et al.: Antimicrob. Agents Chemother., 33, 1493 (1989), Robson, C., et al.: J. Med. Chem., 40, 3040 (1997), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Janin, Y., et al.: Bioorg. Med. Chem., 15, 2479 (2007),<br></p>Formula:C11H10ClNOColor and Shape:White To BrownMolecular weight:207.66N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea
CAS:Controlled ProductFormula:C10H15N5S2Color and Shape:NeatMolecular weight:269.39[3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)phenyl]amine hydrobromide
CAS:Formula:C13H19BrN2O4Color and Shape:Beige powderMolecular weight:347.209Risperidone-d4
CAS:Controlled Product<p>Applications A deuterated version of Risperidone (R525000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formula:C232H4H23FN4O2Color and Shape:BeigeMolecular weight:414.51Haloperidol
CAS:Controlled Product<p>Applications Antidyskinetic; antipsychotic. Neuroprotective product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janicki, C.A., et al.: Anal. Profiles Drug Subs., 9, 341 (1980), Beresford, R., et al.: Drugs, 33, 31 (1987)<br></p>Formula:C21H23ClFNO2Color and Shape:Off-WhiteMolecular weight:375.862-Nitrobenzotrifluoride
CAS:Controlled Product<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Formula:C7H4F3NO2Color and Shape:NeatMolecular weight:191.107Propoxyphenyl Thiosildenafil
CAS:Controlled Product<p>Applications Propoxyphenyl-thiosildenafil is an analogue of Thiosildenafil (T371500). Propoxyphenyl-thiosildenafil has been used in the preparation of novel pyrazolopyrimidinethiones as PDE5 inhibitors for treating erectile dysfunction.<br></p>Formula:C23H32N6O3S2Color and Shape:NeatMolecular weight:504.672-Benzylacrylic Acid
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 2-Benzylacrylic Acid (cas# 5669-19-2) is a compound useful in organic synthesis.<br></p>Formula:C10H10O2Color and Shape:NeatMolecular weight:162.195-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Controlled ProductFormula:C13H14N2Color and Shape:NeatMolecular weight:198.26N-Nitroso-Vildagliptin
CAS:Controlled ProductFormula:C17H24N4O3Color and Shape:NeatMolecular weight:332.4rac-Talinolol
CAS:Controlled Product<p>Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Formula:C20H33N3O3Color and Shape:White To Light PinkMolecular weight:363.49Ethyl 3-(4-Bromophenyl)-1-methyl1H-pyrazole-5-carboxylate
CAS:Formula:C13H13BrN2O2Purity:95.0%Color and Shape:SolidMolecular weight:309.163(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde
CAS:Purity:95%Molecular weight:317.3630065917969Relcovaptan
CAS:<p>Stability Hygroscopic<br>Applications Relcovaptan is a selective vasopressin-1a receptor antagonist that prevents cellular swelling and provides treatment for post-traumatic brain edema.<br>References Marmarou, C.R., et. al.: Brain Res., 1581, 89 (2014)<br></p>Formula:C28H27Cl2N3O7SColor and Shape:NeatMolecular weight:620.501-(4-Fluorophenyl)-4-(4-(pyridin-2-yl)piperazin-1-yl)butan-1-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:327.40301513671875Amisulpride-d5 N-Oxide
CAS:Controlled Product<p>Applications Labelled Amisulpride N-Oxide (A633265). Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride.<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Formula:C17H22D5N3O5SColor and Shape:WhiteMolecular weight:390.513-(4-CHLOROPHENYL)-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
CAS:Purity:95.0%Molecular weight:282.7300109863281Darunavir
CAS:<p>Applications Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Formula:C27H37N3O7SColor and Shape:BeigeMolecular weight:547.66(4S)-Brivaracetam
CAS:Controlled ProductFormula:C11H20N2O2Color and Shape:NeatMolecular weight:212.2892-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:293.3219909667969N-[2-(3,4-Dihydro-1-oxo-2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide
CAS:Controlled Product<p>Impurity Praziquantel USP Related Compound C<br>Applications N-[2-(3,4-Dihydro-1-oxo-v2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide is a compound related to Praziquantel (P702095),effective against flatworms. Praziquantel USP Related Compound C.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formula:C19H22N2O4Color and Shape:NeatMolecular weight:342.39rac Mirabegron-d5
CAS:Controlled ProductFormula:C21H19D5N4O2SColor and Shape:NeatMolecular weight:401.545-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity F<br>Stability Hygroscopic<br>Applications 5-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride (Ranitidine EP Impurity F) is an intermediate in the synthesis of Ranitidine hydrochloride (R120000).<br>References Salameh, A., et al.: J. Food Sci., 71, 10 (2006), Guerrieri, P., et al.: Pharm. Res., 24, 147 (2007),<br></p>Formula:C8H13NO2·ClHColor and Shape:BrownMolecular weight:191.66Pyrimethamine
CAS:Controlled Product<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Formula:C12H13ClN4Color and Shape:White To Off-WhiteMolecular weight:248.71Etoricoxib-d3
CAS:Controlled Product<p>Applications A specific inhibitor of COX-2 .<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Formula:C182H3H12ClN2O2SColor and Shape:NeatMolecular weight:361.86Kynurenic Acid
CAS:<p>Applications A product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>Formula:C10H7NO3Color and Shape:NeatMolecular weight:189.17Flibanserin N-Oxide
CAS:Controlled ProductFormula:C20H21F3N4O2Color and Shape:NeatMolecular weight:406.401Apatinib
CAS:Controlled Product<p>Applications Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mi, Y. et al.: Cancer Res., 70, 7981 (2010); Tong, X.Z. et al.: Biochem. Pharmacol., 83, 586 (2012); Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012);<br></p>Formula:C24H23N5O·CH4O3SColor and Shape:NeatMolecular weight:493.58{3-[3-(2-thienyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]phenyl}amine
CAS:Purity:95.0%Molecular weight:293.35000610351564-(4-Nitrophenyl)-3-morpholinone
CAS:Controlled ProductFormula:C10H10N2O4Color and Shape:NeatMolecular weight:222.20Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Controlled Product<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Formula:C11H13N2O3ClColor and Shape:NeatMolecular weight:256.68Valsartan Benzyl Ester
CAS:<p>Impurity Valsartan USP Related Compound C<br>Applications Valsartan (V095750) intermediate. Valsartan USP Related Compound C.<br>References Cramer., et al.: J. Med. Chem., 42, 3919 (1999),<br></p>Formula:C31H35N5O3Color and Shape:NeatMolecular weight:525.643-[2-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Hydrochloride
CAS:Controlled Product<p>Applications Risperidone (R525000) metabolite.<br>References Meuldermans, W. et al.; Drug Metab. Dispos. 22, 129 (1994); Mannens, G. et al.; Drug Metab. Dispos. 21, 1134 (1993)<br></p>Formula:C23H28FN3O3·HClColor and Shape:NeatMolecular weight:449.946Xanthurenic Acid
CAS:<p>Applications Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Formula:C10H7NO4Color and Shape:NeatMolecular weight:205.17(S) FTY720 Phosphate
CAS:<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005<br></p>Formula:C19H34NO5PColor and Shape:WhiteMolecular weight:387.45ABT 199 (Venetoclax)
CAS:Controlled Product<p>Applications ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.<br>References Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);<br></p>Formula:C45H50ClN7O7SColor and Shape:Light Yellow To YellowMolecular weight:868.442-(Diphenylmethoxy)-N-methylethylamine
CAS:Controlled Product<p>Applications 2-(Diphenylmethoxy)-N-methylethylamine is used in the pereparation of H1 and H2 receptor antagonists containing Diphenhydramine (D486900) derivatives. Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine (D486900) is categorized as an antihistaminic; sedative, hypnotic.<br>References Wolf, C. et al.: Archiv. de Pharm., 329, 87 (1996); Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),<br></p>Formula:C16H19NOColor and Shape:Light Yellow To YellowMolecular weight:241.33Apalutamide
CAS:Controlled Product<p>Applications Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formula:C21H15F4N5O2SColor and Shape:White To Off-WhiteMolecular weight:477.4347Aripiprazole-d8
CAS:Controlled Product<p>Applications Aripiprazole-d8 is a deuterated version of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Formula:C232H8H19Cl2N3O2Color and Shape:Off White SolidMolecular weight:456.43Terbufoxon Sulfone
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Terbufoxon Sulfone is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Formula:C9H21O5PS2Color and Shape:NeatMolecular weight:304.36
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