Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Rotigotine
CAS:<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Formula:C19H25NOSPurity:99.04% - 99.88%Color and Shape:SolidMolecular weight:315.47Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.34Dronedarone Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>Formula:C31H44N2O5S·ClHColor and Shape:NeatMolecular weight:593.223-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:318.8599853515625endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine
CAS:Controlled Product<p>Impurity Granisetron EP Impurity E<br>Applications Granisetron impurity E. An intermediate of Granisetron.<br>References McCallum, R., et al.: Drugs, 36, 652 (1988), Kaumann, A., et al.: Br. J. Pharmacol., 100, 879 (1990), Mohr, K., et al.: Pharmacol. Toxicol., 70, 198 (1992), Van, W.A., et al.: Nucl. Med. Biol., 21, 41 (1994), Mize, A., et al.: Brain Res., 836, 229 (1999),<br></p>Formula:C9H18N2Color and Shape:NeatMolecular weight:154.253Captopril
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor. Neuroprotective & Neuroresearch Product.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9H15NO3SColor and Shape:NeatMolecular weight:217.29Deoxy Epinephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Andregenic and dopamine receptor agonist; active metabolite of Ibopramine (I123500). Also, it is used as internal standard in chromatographic analysis of catecholamines.<br>References Kindler, P., et al.: Arch. Pharm., 270, 340 (1932), Bridgers, W.F., et al.: J. Biol. Chem., 237, 526 (1962),<br></p>Formula:C9H13NO2·ClHColor and Shape:Light Brown To PurpleMolecular weight:203.67rac-Monepantel Sulfone
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications rac-Monepantel Sulfone is a derivative of Monepantel (M515800), a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Formula:C20H13F6N3O4SColor and Shape:NeatMolecular weight:505.39N-Formyl Apixaban
CAS:Controlled Product<p>Applications N-Formyl Apixaban is derived from Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C26H25N5O5Color and Shape:NeatMolecular weight:487.51Furagin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agace, W., et al.: J. Clin. Invest., 92, 780 (1993); Lawrenson, R., et al.: J. Antimicrob. Chemother., 48, 895 (2001); Dalhoff, A., et al.: Lancet Infect. Dis., 3, 359 (2003); Thumbikat, P., et al.: J. Immunol., 176, 3080 (2006);<br></p>Formula:C10H8N4O5Color and Shape:NeatMolecular weight:264.19N-Nitroso Desmethyldiphenhydramine
CAS:Controlled ProductFormula:C16H18N2O2Color and Shape:NeatMolecular weight:270.326Ref: 10-F987646
1gTo inquire5gTo inquire5mg80.00€10mg102.00€25mg211.00€50mg362.00€100mgTo inquire250mgTo inquire6-methoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:271.3399963378906Empagliflozin (Tetrahydrofuranyl-d4)
CAS:Controlled Product<p>Applications Empagliflozin-d4 is a labelled analog of Empagliflozin (E521510); a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C23D4H23ClO7Color and Shape:NeatMolecular weight:454.9343-Methyl-1H-indene-2-carboxylic acid
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:174.19900512695312Pinaverium Bromide
CAS:<p>Applications Spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic.<br>References Jacquot, C., et al.: Eur. J. Med. Chem., 13, 61 (1978), Bretaudeau, J., et al.: J. Pharmacol., 11, 233 (1980), Bertrand, J., et al.: Therapie, 36, 555 (1981),<br></p>Formula:C26H41BrNO4·BrColor and Shape:NeatMolecular weight:591.42N-Demethyl Ivabradine Hydrochloride
CAS:Controlled ProductFormula:C26H34N2O5·ClHColor and Shape:NeatMolecular weight:491.027-(Benzyloxy)quinolin-4-ol
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:251.28500366210938Fluazuron
CAS:Controlled Product<p>Applications A pesticide, like other BPUs it interferes with chitin synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamada, R., et al.: Biosci., Biotechnol., Biochem., 70, 54 (2006), Kryger, U., et al.: Vet. Parasitol., 143, 380 (2007), Arakawa, T., et al.: App. Entomol. Zool., 43, 167 (2008),<br></p>Formula:C20H10Cl2F5N3O3Color and Shape:White To Off-WhiteMolecular weight:506.21rac Penbutolol-d9
CAS:Controlled Product<p>Applications Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Formula:C18H20D9NO2Color and Shape:White To Off-WhiteMolecular weight:300.482-(2-chlorophenyl)-6-methylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:297.739990234375Methyl 2-(4-aminophenyl)quinoline-4-carboxylate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:278.31100463867192-(6-methylpyridin-2-yl)-1,3-dioxoisoindoline-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:282.2550048828125[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol
CAS:Controlled Product<p>Applications [2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol is used in the preparation of azepine.<br>References Lypacewicz, Maria K. et al., Pol.(1998);<br></p>Formula:C18H22N2OColor and Shape:White To Light BeigeMolecular weight:282.38(S)-2-((tert-Butoxycarbonyl)amino)pentane-1,5-diyl Dimethanesulfonate
CAS:Controlled ProductFormula:C12H25NO8S2Color and Shape:NeatMolecular weight:375.459Mosapride N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Mosapride (M731000).<br>References Chen, H., et al.: J. Pharm. Biomed. Anal., 40, 142 (2006), Pedraglio, S., et al.: J. Pharm. Biomed. Anal., 44, 665 (2007), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008), Curran, M., et al.: Drugs, 68, 981 (2008),<br></p>Formula:C21H25ClFN3O4Color and Shape:NeatMolecular weight:437.89(AlphaR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine Hydrochloride
CAS:Controlled Product<p>Applications (αR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).<br>References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003), Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),<br></p>Formula:C22H25NColor and Shape:NeatMolecular weight:303.443-Bromo-5-(3-cyclopropyl-[1,2,4]oxadiazol-5-yl)-pyridine
Purity:95.0%Molecular weight:266.09799194335943-(1-Methanesulfonyl-3,5-dimethyl-1 H -pyrazol-4-yl)-propionic acid ethyl ester
CAS:Formula:C11H18N2O4SPurity:97%Color and Shape:SolidMolecular weight:274.34Apalutamide
CAS:Controlled Product<p>Applications Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formula:C21H15F4N5O2SColor and Shape:White To Off-WhiteMolecular weight:477.4347Toceranib
CAS:<p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>Formula:C22H25FN4O2Purity:97.14%Color and Shape:SolidMolecular weight:396.465-methoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:271.33999633789066-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide
CAS:Controlled Product<p>Applications Intermediate in the production of Lornoxicam. An analgesic, anti-inflammatory agent.<br></p>Formula:C9H8ClNO5S2Color and Shape:NeatMolecular weight:309.75(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediamine
CAS:Controlled Product<p>Applications Pramipexole derivative.<br></p>Formula:C13H19N3O2SColor and Shape:NeatMolecular weight:281.37Desmethyl Amisulpride Hydrobromide
CAS:Controlled ProductFormula:C16H26BrN3O4SColor and Shape:NeatMolecular weight:436.362-(3-(pyridin-4-yl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethan-1-amine
CAS:Purity:95.0%Molecular weight:242.32600402832031,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:Controlled Product<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Formula:C17H17N3OColor and Shape:White To Off-WhiteMolecular weight:279.34
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