Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65615 products of "Quinazoline and Quinoline Derivatives"
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Empagliflozin Methyl Acetate
CAS:<p>Applications Empagliflozin Methyl Acetate is an impurity of Empagliflozin (E521510), which is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C25H29ClO8Color and Shape:White To Off-WhiteMolecular weight:492.954-Chlorobenzamide
CAS:Controlled Product<p>Applications 4-chlorobenzamide (cas# 619-56-7) is a useful research chemical.<br></p>Formula:C7H6ClNOColor and Shape:NeatMolecular weight:155.58Desethylcarbamoyl Cabergoline
CAS:Controlled Product<p>Impurity Cabergoline EP Impurity D<br>Applications A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum<br>References Battaglia, R., et al.: Xenobiotica, 23, 1377 (1993), Miyagi, M., et al.: Biol. Pharm. Bull., 19, 1210 (1996),<br></p>Formula:C23H32N4OColor and Shape:Beige SolidMolecular weight:380.537-Despropyl 7-Methyl Vardenafil
Controlled Product<p>Applications 7-Despropyl 7-Methyl Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.<br>References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)<br></p>Formula:C21H28N6O4SColor and Shape:Off White SolidMolecular weight:460.55Vildagliptin-d3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H22D3N3O2Color and Shape:NeatMolecular weight:306.42Salsalate-d8
CAS:Controlled Product<p>Applications Isotope labelled Nonacetylated aspirin analog. Analgesic, anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980), Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),<br></p>Formula:C14H2D8O5Color and Shape:NeatMolecular weight:266.28(+/-)-4-Hydroxy Mephenytoin
CAS:Controlled Product<p>Applications CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formula:C12H14N2O3Color and Shape:White SolidMolecular weight:234.253-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Controlled Product<p>Impurity Paliperidone USP Related Compound C<br>Applications Paliperidone USP Related Compound C<br></p>Formula:C11H15ClN2O2Color and Shape:Light Yellow To BrownMolecular weight:242.70Carmustine
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),<br></p>Formula:C5H9Cl2N3O2Color and Shape:Light Yellow To Light Orange ColourMolecular weight:214.05Seleno-D,L-ethionine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Used as a substrate for methionine adenosyltransferase from rat liver.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lombardini, J.B., et al.: Biochem. Pharmacol., 32(3), 489 (1983), Kajander, E., et al.: Cancer Res., 46 (6), 2866 (1986), Kajander, E., et al.: Biochem. J., 267 (3), 767 (1990)<br></p>Formula:C6H13NO2SeColor and Shape:Off-White To Light BeigeMolecular weight:210.13Axitinib Tetrahydro-2H-pyran
CAS:Controlled ProductFormula:C27H26N4O2SColor and Shape:NeatMolecular weight:470.586(+/-)-Epinephrine Hydrochloride
CAS:Controlled Product<p>Applications (+/-)-Epinephrine hydrochloride is an adrenergic receptor agonist; Neurotransmitter; Causes suppression of efferent activity of the adrenal nerve.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirano, T., et al.: J. Auton. Nerv. Syst., 1, 283-290 (1980)<br></p>Formula:C9H13NO3·ClHColor and Shape:Off-WhiteMolecular weight:219.67Timolol Maleate
CAS:<p>Applications Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.<br>References Wasson, et al.: J. Med. Chem., 15, 651 (1972), Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972), Heel, R.C., et al.: Drugs, 17, 38 (1979), Rofman, B.A., et al.: Hypertension, 2, 643 (1980), Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987),<br></p>Formula:C13H24N4O3S·C4H4O4Color and Shape:NeatMolecular weight:432.49Meloxicam-d3
CAS:Controlled Product<p>Applications Labelled form of Meloxicam. Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Formula:C142H3H10N3O4S2Color and Shape:Light Yellow To YellowMolecular weight:354.42Desisopropyl Atrazine-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Formula:C52H5H3ClN5Color and Shape:Off-WhiteMolecular weight:178.63Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (85%) (Famotidine Impurity)
CAS:Controlled ProductFormula:C10H14N8S4Color and Shape:Off-WhiteMolecular weight:374.53Asenapine N-Oxide
CAS:Controlled Product<p>Applications A metabolite of Asenapine (A788000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ven der Wildenberg, H.M., et al.: Arzneim.-Forsch., 40, 540 (1990),<br></p>Formula:C17H16ClNO2Color and Shape:NeatMolecular weight:301.77tert-Butyl (R)-3-Aminopiperidine-1-carboxylate
CAS:Controlled Product<p>Applications tert-Butyl (R)-3-Aminopiperidine-1-carboxylate, is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Aβ42 production in both in vitro and in vivo.<br>References Kobayashi, T., et al.: Bioorg. Med. Chem. Lett., 24, 378 (2014);<br></p>Formula:C10H20N2O2Color and Shape:NeatMolecular weight:200.28Reserpine-d9
CAS:Controlled Product<p>Applications Labelled Reserpine (R144600). An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Formula:C332H9H31N2O9Color and Shape:NeatMolecular weight:617.73Propyzamide
CAS:Controlled Product<p>Applications Selective pre-emergence herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viste, K.L., et al.: Science, 167, 280 (1970), Yoshii, K., et al.: J. Agric. Food Chem., 48, 2502 (2000), Paya, P., et al.: Anal. Bioanal. Chem., 389, 1697 (2007),<br></p>Formula:C12H11Cl2NOColor and Shape:WhiteMolecular weight:256.13(R)-Albuterol Hydrochloride
CAS:Controlled Product<p>Applications The R-enantiomer of Albuterol (A514500). A β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References Han, et al.: Bioorg. Med. Chem., 14, 6043 (2006), Liyou, H., et al.: Biochem., 46, 1432 (2007), Agrawal, D., et al.: J. Allergy Clin. Immunol., 113, 503 (2004),<br></p>Formula:C13H21NO3·ClHColor and Shape:Off-WhiteMolecular weight:275.772-Phenylbutyric Acid
CAS:Controlled ProductFormula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.2Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H22N4O3Color and Shape:NeatMolecular weight:330.38Prochlorperazine Dimaleate
CAS:Controlled ProductFormula:C20H24ClN3S·2C4H4O4Color and Shape:Off-WhiteMolecular weight:606.09Saquinavir Mesylate
CAS:Controlled Product<p>Applications A selective HIV protease inhibitor. Antiviral.<br>References Roberts, N.A., et al.: Science, 248, 358 (1990), Craig, J.C., et al.: Antiviral Res., 16, 295 (1991),<br></p>Formula:C38H50N6O5·CH4O3SColor and Shape:NeatMolecular weight:766.95N-Nitroso Lisinopril
CAS:Formula:C21H30N4O6Color and Shape:White To Light YellowMolecular weight:434.486N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Controlled ProductFormula:C25H26ClNO3Color and Shape:NeatMolecular weight:423.93Mitotane
CAS:Controlled Product<p>Applications An Antineoplastic. Used as an adrenolytic agent.<br>References Das, S., and Thomas, P.: Endocrinology, 140, 1953 (1999), Andersen, A., et al.: Ther. Drug. Monit., 21, 355 (1999), Leblond, V.S., and Hontela, T.: Toxicol. Appl. Pharmacol., 157, 16 (1999)<br></p>Formula:C14H10Cl4Color and Shape:White To Off-WhiteMolecular weight:320.04Nor Mianserin-d6 (Major)
Controlled Product<p>Applications Nor Mianserin-d6 (Major), is a labeled analogue of Nor Mianserin (N736800), an active metabolites of Miansein (M341500) in plasma, an antidepressant.<br>References Kent, J., et al.: Lancet, 355, 911 (2000), Maurer, H., et al.: Ther. Drug Monit., 24, 117 (2002),<br></p>Formula:C17H14D6N2Color and Shape:NeatMolecular weight:258.392,6-Dichloroformanilide
CAS:Controlled Product<p>Applications 2,6-Dichloroformanilide is an intermediate in the synthesis of N-(2,6-Dichlorophenyl)-carbonimidic Dichloride (D436565). N-(2,6-dichlorophenyl)-carbonimidic Dichloride is an impurity of clonidine (C587130). Chlonidine is α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roach, A.G., et al.: J. Pharmacol. Exp. Ther., 227, 421 (1983), Glassman, A.H., et al.: Science, 226, 864 (1984), Abounassif, A.M., et al.: Anal. Profiles Drug Subs. Excip., 21, 109 (1992),<br></p>Formula:C7H5Cl2NOColor and Shape:NeatMolecular weight:190.03Nadolol
CAS:Controlled Product<p>Applications β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977), Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978), Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980),<br></p>Formula:C17H27NO4Color and Shape:Off-WhiteMolecular weight:309.40Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Formula:C8H5F3N2OSPurity:99.71% - 99.88%Color and Shape:PowderMolecular weight:234.211-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 11-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine is an impurity of Quetiapine hemifumarate (Q510000), a dibenzothiazepine antipsychotic medication used in the treatment of schizophrenia.<br>References Kumar, K., et al.: Org. Chem.: An Indian Journal, 8, 164 (2012); Raju, I., et al.: Chromatographia, 70, 545 (2009)<br></p>Formula:C19H23Cl2N3SColor and Shape:NeatMolecular weight:396.38p-Chlonixin
CAS:<p>Applications p-Chlonixin may be used in pharmaceutical tablet dosage formulations.<br>References Kumar, M. N., et al.: I. J. Pharm., 5, 170-179 (2015)<br></p>Formula:C13H11ClN2O2Color and Shape:NeatMolecular weight:262.69Famotidine Acid
CAS:Controlled Product<p>Impurity Famotidine EP Impurity F<br>Stability Light Sensitive<br>Applications Famotidine impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C8H12N4O2S2Color and Shape:NeatMolecular weight:260.34Famotidine
CAS:Controlled Product<p>Applications Histamine H2-receptor antagonist. Antiulcerative.<br>References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),<br></p>Formula:C8H15N7O2S3Color and Shape:White To Off-WhiteMolecular weight:337.45Famotidine Acid Methyl Ester Hydrochloride (Famotidine Impurity)
CAS:Controlled Product<p>Applications Famotidine acid methyl ester hydrochloride salt is a Famotidine (F102250) impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C9H14N4O2S2·ClHColor and Shape:NeatMolecular weight:310.82Famotidine Amide Impurity Hydrochloride
CAS:<p>Applications Famotidine impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C8H14ClN5OS2Color and Shape:White SolidMolecular weight:295.817-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Formula:C18H19N3O2Color and Shape:NeatMolecular weight:309.362(R)-Monepantel Sulfone
CAS:<p>Applications Montepantel Sulfone is a derivative of Monepantel (M515800), a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Formula:C20H13F6N3O4SColor and Shape:NeatMolecular weight:505.391-(1-BENZYL-1H-PYRAZOL-4-YL)-1H-INDOLE-3-CARBOXYLIC ACID
Purity:90.0%Molecular weight:317.34799194335941-(4-Fluorophenyl)-3-thiophen-2-yl-1H-pyrazole-5-carboxylic acid
CAS:Purity:98.0%Color and Shape:Solid, Off-white powderMolecular weight:288.299987792968756-methoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:271.33999633789064-Chloro-1-(4-fluorophenyl)-3-methyl-1H-pyrazol-5-amine
CAS:Purity:95%Molecular weight:225.64999389648438
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