Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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2-Amino-3,4-dimethylpyridine
CAS:Formula:C7H10N2Purity:98%Color and Shape:SolidMolecular weight:122.171Dutasteride a-Dimer (~90%)
CAS:Controlled Product<p>Applications Dutasteride α-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C46H55F6N3O4Purity:~90%Color and Shape:Off-WhiteMolecular weight:827.943-Phenyl-4-thioxo-3,4-dihydrophthalazine-1-carboxylic acid
CAS:Purity:98%Molecular weight:282.32000732421875Clofedanol Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.<br>References Yuizono, T., et al.: Yakugaku Zasshi, 87, 915 (1967), Nomura, A., et al.: Oyo Yakuri, 8, 119 (1974),<br></p>Formula:C17H20ClNO·ClHColor and Shape:White To Off-WhiteMolecular weight:326.262,6-Dichloro-N-methyl-3-nitropyridin-4-amine
CAS:Purity:98%Color and Shape:SolidMolecular weight:222.0299988Isoanastrozole
CAS:Controlled Product<p>Impurity Anastrozole EP Impurity G<br>Applications Isoanastrozole (Anastrozole EP Impurity G) is used in the preparation of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Zhu, Y., et. al.: Faming Zhuanli Shenqing, CN 103524439 A 20140122 (2014)<br></p>Formula:C17H19N5Color and Shape:WhiteMolecular weight:293.371,2-Diisonicotinoylhydrazine
CAS:Controlled Product<p>Applications 1,2-Diisonicotinoylhydrazine is an iron chelator.<br>References Bernhardt, P.V., et. al.: J. Biol. Inorg. Chem., 10, 761 (2005)<br></p>Formula:C12H10N4O2Color and Shape:NeatMolecular weight:242.232'-[(1H-Tetrazol-5-yl)biphenyl-4-yl]methanol
CAS:Controlled Product<p>Applications Losartan (L470500) impurity.<br>References Huskey, S., et al.: Drug Metab. Dispos., 22, 651 (1994), Herr, R., et al.: Bioorg. Med. Chem., 10, 3379 (2002),<br></p>Formula:C14H12N4OColor and Shape:NeatMolecular weight:252.272,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone
CAS:Controlled ProductFormula:C6H8O4Color and Shape:NeatMolecular weight:144.138-chloro-2-(3-methylphenyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:297.7399902343751-(2-CHLOROPHENYL)ISOQUINOLINE-3-CARBOXYLIC ACID
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:283.70999145507813-Oxo-3-thiophen-2-yl-propionic acid methyl ester
CAS:Formula:C8H8O3SPurity:95.0%Color and Shape:LiquidMolecular weight:184.21Myristicin Acid Methyl Ester
CAS:Controlled Product<p>Applications Myristicin Acid Methyl Ester is an intermediate in the synthesis of natural dihydrostilbenes with significant cytotoxicity toward human cancer cell lines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kobayashi, H., et al.: J. Antibiotics, 49, 873 (1996), Belguendouz, L., et al.: Biochem. Pharmacol., 53, 1347 (1997), Mu, F., et al.: J. Med. Chem., 46, 1670 (2003), Lee, J., et al.: Bioorg. Med. Chem., 14, 2022 (2006),<br></p>Formula:C10H10O5Color and Shape:NeatMolecular weight:210.18Primidone-d5
CAS:Controlled Product<p>Applications Anticonvulsant.<br>References Bogue, C., et al.: Br. J. Pharmacol., 8, 230 (1953), Daley, R.D., Anal. Profiles Drug Subs., 2, 409 (1973),<br></p>Formula:C122H5H9N2O2Color and Shape:Off-WhiteMolecular weight:223.28Bicalutamide Sulfide
CAS:Controlled ProductFormula:C18H14F4N2O2SColor and Shape:WhiteMolecular weight:398.374-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:<p>Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Formula:C21H16Cl2N2O3Color and Shape:NeatMolecular weight:415.273-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
CAS:Controlled Product<p>Applications 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one (cas# 545445-44-1) is a useful research chemical.<br></p>Formula:C20H25O3N3Color and Shape:BeigeMolecular weight:355.433-(Pyridin-3-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid
CAS:Molecular weight:240.2220001220703Levofloxacin-d3 Sodium Salt
CAS:Controlled Product<p>Applications Levofloxacin-d3 Sodium Salt, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Formula:C18H16D3FN3NaO4Color and Shape:NeatMolecular weight:386.37Dolutegravir Sodium
CAS:<p>Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)<br></p>Formula:C20H18F2N3O5·NaColor and Shape:NeatMolecular weight:441.36Diminazene-13C2,15N4 Dihydrochloride (major)
CAS:<p>Applications Labelled Diminazene (D479550). Antiprotozoal (Trypanosoma, Babesia).<br>References Braithwaite, A.W.<br></p>Formula:C1213C2H17Cl2N315N4Color and Shape:Yellow To Dark YellowMolecular weight:360.2Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26Indomethacin Diamide
CAS:Controlled Product<p>Applications Indomethacin Diamide is an impurity of Indomethacin (I641000), an non-steroidal anti-inflammatory drug commonly used in the treatment of fever, pain and swelling.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Formula:C33H27Cl2N3O5Color and Shape:NeatMolecular weight:616.49Domperidone
CAS:<p>Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Formula:C22H24ClN5O2Color and Shape:White To Off-WhiteMolecular weight:425.913-Pyrazin-2-ylpropanoic acid
CAS:Formula:C7H8N2O2Purity:95.0%Color and Shape:SolidMolecular weight:152.1534'-Formylbiphenyl-2-carbonitrile
CAS:Controlled Product<p>Applications 4'-Formylbiphenyl-2-carbonitrile is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br>References Goossen, L.J., et al.: J. Org. Chem., 72, 7473 (2007);<br></p>Formula:C14H9NOColor and Shape:NeatMolecular weight:207.22745-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
CAS:Purity:97.0%Molecular weight:473.8900146484375Zaltoprofen
CAS:Controlled Product<p>Applications Zaltoprofen is a non-steroidal anti-inflammatory drug. It inhibits bradykinin-induced pain responses without blocking bradykinin receptors.<br>References Hirate, K., et al.: Nerosci. Res., 54, 288 (2006); Yamamoto, M., et al.: Chirality, 2, 280 (1990); Inoue, M., et al.: J Pharmacol. Exp. Ther., 293, 662 (2000); Graven-Nielsen, T., et al.: Clin. J. Pain, 17, 2 (2001)<br></p>Formula:C17H14O3SColor and Shape:NeatMolecular weight:298.362-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Formula:C13H11NOSColor and Shape:Grey To BrownMolecular weight:229.30N-Nitrosocarvedilol
CAS:Controlled ProductFormula:C24H25N3O5Color and Shape:NeatMolecular weight:435.472Everolimus
CAS:Controlled Product<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Formula:C53H83NO14Purity:~90%Color and Shape:NeatMolecular weight:958.226-methyl-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:277.3229980468755,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one Oxime Hydrochloride
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity G<br>Stability Hygroscopic<br>Applications 5,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one Oxime Hydrochloride (Ranitidine EP Impurity G) is a Ranitidine HCl (R120000) impurity.<br>References Wu, V., et al.: Pharmazie, 55, 508 (2000), Salameh, A., et al.: J. Food Sci., 71, E10 (2006),<br></p>Formula:C5H9N3OS·ClHColor and Shape:NeatMolecular weight:195.674-(2-Methoxyethyl)phenol
CAS:Controlled Product<p>Impurity Metoprolol EP Impurity B<br>Applications 4-(2-Methoxyethyl)phenol (Metoprolol EP Impurity B) is an impurity of Metoprolol.<br>References McGourty, J., et al.: Br. J. Clin. Pharmacol., 20, 555 (1985), Zhou, H., et al.: Clin. Pharmacol. Ther., 47, 686 (1990), Koyama, E., et al.: J. Pharmacol. Exp. Ther., 271, 860 (1994)<br></p>Formula:C9H12O2Color and Shape:NeatMolecular weight:152.19(R)-(+)-Bupivacaine Hydrochloride
CAS:<p>Applications (R)-(+)-Bupivacaine Hydrochloride is a local anaesthetic used for epidural and intrathecal anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tullar, B., et al.: J. Med. Chem., 14, 891 (1971), Schmidt, A., et al.: Pharm. Res., 22, 2121 (2005),<br></p>Formula:C18H28N2O·HClColor and Shape:NeatMolecular weight:324.89Pibrentasvir
CAS:Controlled Product<p>Applications Pibrentasvir (CAS# 1353900-92-1) is an antiviral used for hepatitis C virus NS3/4A protease inhibition.<br>References Ng, T. I.; et al.: Antimicrob. Agents Chemother., 62, 1 (2018).<br></p>Formula:C57H65F5N10O8Color and Shape:Off-White To Light YellowMolecular weight:1113.18S-(-)-Sulpiride-d3
CAS:Controlled Product<p>Applications Labelled S-(-)-Sulpiride (S689140). Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.<br>References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),<br></p>Formula:C152H3H20N3O4SColor and Shape:White To Light GreenMolecular weight:344.44Ponazuril
CAS:Controlled Product<p>Applications Antiprotazoal, used to treat Equine Protozoal Myeloencephalitis (EPM).<br>References Mitchell, S., et al.: J. Parasitol., 90, 639 (2004), Didikolu, L., et al.: J. Vet. Pharmacol. Ther., 32, 368 (2009), Martinez-Villalba, A., et al.: Anal. Bioanal. Chem., 397, 2893 (2010),<br></p>Formula:C18H14F3N3O6SColor and Shape:Off WhiteMolecular weight:457.38Roflumilast-d4
CAS:Controlled Product<p>Applications Labelled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.<br>References Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001), Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001), Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002), Rabe, K.F., et al.: Lancet, 366, 563 (2005),<br></p>Formula:C17D4H10Cl2F2N2O3Color and Shape:NeatMolecular weight:407.23N-(2-Benzylphenyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide
CAS:Purity:98%Molecular weight:354.40899658203125
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