Monosaccharides

Inositol nicotinate is a combination of two substances, inositol and nicotinate. It is used to reduce the risk of heart disease by lowering low-density lipoprotein-cholesterol (LDL) levels. Inositol nicotinate has been shown to increase the surface area of mitochondria, which may be due to its ability to inhibit the release of fatty acids from fat cells. Inositol nicotinate also increases magnesium levels in cells and induces mitochondrial functions. This drug has been tested in cell culture for its effects on skin cells and found that it can reduce the amount of x-linked adrenoleukodystrophy protein (XALD), a substance that accumulates in patients with X-linked adrenoleukodystrophy, an inherited disorder that causes progressive damage to the nervous system. The drugs also have been shown to have beneficial effects on cholesterol metabolism, reducing LDL cholesterol levels, as well as inhibiting platelet aggregation.

6-O-Benzoyl-3-O-tert-butyldimethylsilyl-D-glucal is a custom synthesis that is used in the modification of monosaccharides and oligosaccharides. It is a synthetic molecule that has been modified with fluorination, methylation, and click chemistry. This product is a saccharide with a CAS number.

Losartan N1-glucuronide is a glucuronidated metabolite of losartan that is produced naturally in the human body. It is converted from losartan by the enzyme UDP-glucuronosyltransferase, which is found in humans and other animals. The rate of glucuronidation varies between individuals and is determined by genetic factors. Losartan N1-glucuronide has shown to be an effective inhibitor of angiotensin II, with an IC50 value of 1.4 μM. This inhibition can be reversed by dobutamine or recombinant human UGT2B7 enzyme, which are both competitive inhibitors of the enzyme UGT2B7. Magnetic resonance spectroscopy has been used to study the kinetic properties of this inhibitor and its effect on dobutamine-induced changes in cardiac function.

D-Arabinopyranosyl thiosemicarbazide is a synthetic compound. It has been shown to be effective in the synthesis of oligosaccharides and sugars, as well as glycosylation reactions. This product can be used in fluorination, methylation, and other custom synthesis reactions. D-Arabinopyranosyl thiosemicarbazide is also useful for click modification of complex carbohydrates. The purity of this product is high and it can be modified with various functional groups.

Phenyl 2-deoxy-2-trichloroacetamido-b-D-thiogalactopyranoside is a custom synthesis that is a complex carbohydrate. It is an oligosaccharide that has CAS No. and is a polysaccharide with Modification, saccharide, Methylation, and Glycosylation. Phenyl 2-deoxy-2-trichloroacetamido-b-D-thiogalactopyranoside has high purity and fluorination which makes it a Synthetic.

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose. It forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.This N-Acetyl-D-galactosamine product (MA184543) is plant-based and produced synthetically from Arabic gum.GalNAc clusters and derivatives, typically composed of three (or more) GalNAc moieties arranged in a specific spatial configuration, are a powerful tool for targeted delivery of nucleic acid therapeutics, specifically in liver targeted therapies. These multivalent ligands effectively bind and internalize via the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatocytes.

Thiotolyl b-D-ribofuranoside is a carbohydrate that is modified with fluorine. It is synthesized from 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and thioglycolic acid in the presence of sodium nitrite. The product is an oligosaccharide that contains a methyl group at C2 and a glycosylation at C6. Thiotolyl b-D-ribofuranoside has been used in the synthesis of polysaccharides with click chemistry reactions.

2,5-Anhydro-3,4-dibenzyl-D-glucitol is a synthetic monosaccharide that has been modified to have a 2,5 anhydro ring and an O-linked glycosylation. It is used in the synthesis of polysaccharides and oligosaccharides. The fluorination at the 3 position protects against degradation by acid hydrolysis. The 2,5 anhydro ring makes this product more stable than other sugars because it does not undergo epimerization reactions with other sugars. This product can be custom synthesized to meet your needs. Please contact us for more information about this product.

A fluorinated fructose analogue

2-Acetamido-1,3,6-tri-O-benzyl-2-deoxy-a-D-glucopyranoside is a carbohydrate that is composed of four sugar units. It is an antigenic determinant found on the surface of human erythrocytes. The chemical synthesis of this substance begins with the condensation reaction between D-glucose and 2,4,6,-trinitrophenylacetic acid followed by benzylation and acetylation. This compound belongs to the group of substances known as carbohydrates which are chains of monosaccharides that form glycosidic bonds with other sugars. These chains are classified according to their length and the number of sugar units they contain: trioses (three sugar units), tetroses (four sugar units), pentoses (five sugar units), hexoses (six sugar units) or heptoses (seven sugar).

2,3,4,6-Tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol is a substituted sugar alcohol that can exist as either an intramolecular or an intermolecular isomer. The intramolecular isomer has a carboxylate group in the 6 position and the intermolecular isomer has a propionate group in the 6 position. 2,3,4,6-Tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol has conformational properties that depend on which substituent occupies the 4 position. Benzene rings are more flexible than benzyloxy groups. The geometry of 2,3,4,6 - Tetra - O - benzyl - 1 , 5 - di - O - mesyl - D - glucitol changes from chair to boat with substitution at position

Fluconazole D-glucuronide is a synthetic, fluorinated sugar that has been modified with a glycosylation. It is synthesized by reacting fluconazole with the sugar glucuronic acid in the presence of an enzyme called glycosyltransferase. Fluconazole D-glucuronide is a custom synthesis, and it can be used as a pharmaceutical intermediate to produce other compounds. Fluconazole D-glucuronide is also used as an analytical standard for quantifying fluconazole in biological samples.

Iminosugar 1 is a fluorinated saccharide that belongs to the group of carbohydrates. It is synthesized by the modification of glucose with a fluorine atom. This modification prevents crystallization and increases solubility in water. Iminosugar 1 has been modified by methylation and glycosylation to increase its stability. This product is available as a custom synthesis, and has high purity.

Main metabolite of antiretroviral drug Abacavir with potent activity against human immunodeficiency virus type 1 (HIV-1). Abacavir is eliminated by hepatic metabolism to two major metabolites: 5’-glucuronide formed by uridine diphosphate glucuronyl transferase and 5’-carboxylate formed by cytosolic alcohol dehydrogenase.

6-Amino-6-deoxy-L-sorbose is a sugar that is metabolized by the body to produce energy. This compound has been shown to be an effective antidiabetic, as it may inhibit glucose production in the liver and enhance insulin sensitivity. 6-Amino-6-deoxy-L-sorbose is a nutrient that can be found in food sources such as bananas, potatoes, and soybeans. It can also be synthesized from various plant sources. The biosynthesis of this compound is dependent on a number of enzymes, including L-arabinose 1 phosphate dehydrogenase.