APIs for research and impurities

<p>Please enquire for more information about (-)-o-Desmethyl-N,N-bisdesmethyl tramadol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.</p>

<p>Guaimesal is a protein analog that acts as an inhibitor of tumor growth and induces apoptosis in human cancer cells. It has been shown to inhibit the activity of kinases, including cyclin-dependent kinases, which play a key role in regulating cell division. Guaimesal has been isolated from Chinese urine and has demonstrated potent anticancer activity both in vitro and in vivo. This compound shows promise as a novel therapeutic agent for the treatment of cancer.</p>

<p>5,6-Dehydro-17beta-dutasteride is a synthetic drug product that is used as an analytical standard for the determination of metabolites and impurities in pharmaceuticals. It also has been used as a natural metabolite, which can be found in human urine. 5,6-Dehydro-17beta-dutasteride is a metabolite of dutasteride, which is an antiandrogen medication for the treatment of benign prostatic hyperplasia (BPH). It is also known to inhibit the metabolism of other drugs such as ketoconazole and metoprolol.</p>

<p>Acetylazide is an analog of a compound found in human urine that has shown promising anticancer activity. It is a potent inhibitor of protein kinases, which are enzymes involved in the regulation of cell growth and division. Acetylazide has been shown to induce apoptosis (cell death) in cancer cells, particularly those associated with thyroid cancer. This compound has also been tested in Chinese hamster ovary cells and has demonstrated a high degree of selectivity for tumor cells over normal cells. Acetylazide may be a promising candidate for the development of new anticancer drugs.</p>

<p>Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.</p>

<p>Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. Valaciclovir Related Compound E can be synthesized from valaciclovir by reacting it with ethyl chloroformate, followed by recrystallization from pyridine and chloroform. This process produces the desired product in high purity under good yield. Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. Valac</p>

<p>(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol (levonorgestrel impurity T) is an analog of levonorgestrel with potent anticancer properties. It has been shown to induce apoptosis in human cancer cell lines by inhibiting kinase and elastase activities. This compound has also been tested against a variety of tumor cell lines and has demonstrated significant anticancer activity. In Chinese hamster ovary cells, levonorgestrel impurity T was found to arrest the cell cycle at the G1 phase, leading to decreased protein synthesis and ultimately cell death. As an inhibitor of kinases and other enzymes involved in cellular signaling pathways, this compound may have potential as a therapeutic agent for the treatment of cancer.</p>

<p>Sodium picosulfate EP Impurity A is a drug product, analytical, Metabolism studies, Natural, API impurity, CAS No. 32500-19-9, Custom synthesis, Impurity standard, Synthetic, Drug development and Research and Development.</p>

<p>The Cl2 linker is an analog of saxagliptin, a kinase inhibitor that has shown promise in the treatment of tumors and cancer. It has been studied extensively in Chinese hamster ovary cells and human urine, where it has demonstrated potent inhibitory activity against a variety of kinases. The Cl2 linker has also been shown to induce apoptosis in cancer cells, making it a potential therapeutic agent for the treatment of cancer. Additionally, it has been investigated as an inhibitor of xylanase, an enzyme involved in the breakdown of plant cell walls. The Cl2 linker may also have potential as an inhibitor of other kinases, such as those targeted by aprepitant, which is used to treat chemotherapy-induced nausea and vomiting.</p>

<p>N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is a cytotoxic drug that belongs to the class of maytansinoids. It is metabolized in vivo to produce cytotoxic metabolites which inhibit protein synthesis by binding to ribosomes, preventing peptide bond formation. The preclinical studies have shown that N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine has a better therapeutic index than other maytansinoids, with fewer side effects. In animal models, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine showed efficacy against human tumor cells and was not toxic to normal cells. This agent also showed no impurities when incubated with human liver microsomes and it was well tolerated in clinical trials in humans</p>

<p>Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.</p>

<p>5-(Hydroxymethyl)-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide is a chemical compound that is used as an analytical reference standard, research and development, drug development and API impurity. 5-(Hydroxymethyl)-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide has a purity of 98% or higher and is available for purchase in bulk quantities. This compound can also be purchased as a HPLC standard, niche product, drug product or impurity standard. 5-(Hydroxymethyl)-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide can be synthesized naturally or synthetically. The CAS number for this chemical is 1058722-46-5.</p>

<p>Ivacaftor is a drug product that is used for the treatment of cystic fibrosis. It is an active ingredient of Kalydeco, which is a combination therapy to treat cystic fibrosis. Ivacaftor is the first FDA-approved drug for the treatment of CF in patients with specific mutations. The metabolism of ivacaftor has been studied by analytical methods and it has been shown to have natural impurities. The API impurity and synthetic impurity standards are available for custom synthesis and can be ordered from a specialty manufacturer. Ivacaftor requires high purity and pharmacopoeia-grade standards for research and development as well as niche markets, such as HPLC standard or high purity.</p>

<p>Fosfomycin trometamol EP impurity A disodium is a research and development impurity standard. It is a custom synthesis that is used as a drug product, synthetic, high purity, pharmacopoeia, drug development, metabolite, niche, analytical and natural. Fosfomycin trometamol EP impurity A disodium has been shown to have an HPLC standard and CAS No. 84954-80-3(free base).</p>

<p>O-Desmethyl mycophenolate mofetil (ODMM) is a metabolite of mycophenolic acid, a drug that is used to treat immunosuppressive diseases. ODMM can be synthesized in the laboratory and used as an analytical standard for mycophenolic acid and its metabolites. ODMM is also a metabolic product of mycophenolate mofetil, which has been shown to have anti-inflammatory properties.</p>

<p>Amoxicillin EP Impurity G is an impurity of Amoxicillin. It is a white to off-white crystalline powder with a melting point of 178 °C. The compound is soluble in alcohol, chloroform, ether, and acetone. This product can be used as an analytical standard for the drug development, niche drug product, or custom synthesis of the drug. Impurity G has been shown to have pharmacopoeia purity and natural origin. It can also be used as an impurity standard for HPLC analysis and pharmaceutical testing.</p>

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a compound that has not been fully characterized. It is a synthetic product with the following chemical structure:</p>

Didesmethylchlorpromazine hydrochloride is an antitumor agent that is resistant to multidrug resistance. It is a potent inhibitor of DNA synthesis and has been shown to sensitize resistant cells to other drugs. Didesmethylchlorpromazine hydrochloride was found to have cytotoxic activity against various human tumor cell lines, including multidrug-resistant cells. However, it did not show any significant activity against normal cells.

<p>Please enquire for more information about 3-(Aminocarbonyl)-1,6-dimethyl-pyridinium iodide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy citalopram oxalate (3HCO) is a drug product that is used as an analytical standard and impurity standard. It is synthesized in the laboratory by reacting 3,4-dihydroxyphenylacetic acid with citalopram, followed by esterification with oxalic acid. The purity of the final product is typically &gt;98%.</p>

<p>The labile character of N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine (DMPD) is due to its high reactivity with peroxide. This chemical reacts with the peroxide molecule to form an unstable intermediate compound that decomposes into two molecules of water and one molecule of hydrogen peroxide. DMPD is also a ligand for many transition metals and has been shown to be a strong electron donor in intramolecular coupling reactions. The catalytic activity of DMPD has been studied extensively using density functional theory and experiments. These studies have shown that DMPD catalyzes the oxidation of hydrocarbons by hydrogen peroxide in the presence of nickel catalyst.</p>

WAY 181187 oxalate is a metabolite of WAY-361507, a drug that has been studied for the treatment of cancer. The chemical structure of WAY 181187 oxalate is shown below.

<p>Please enquire for more information about 4-Acetyloxy-N-despropyl N-tert-butyloxycarbonyl ropivacaine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Threo-hex-2-enaric acid 1,4-lactone 6-methyl ester is a research and development compound. It is a metabolite of the drug product L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester. L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester (LTA) is an impurity in the drug product that is present as a result of its synthesis. LTA is an intermediate compound that can be used to synthesize other drugs or as an analytical reference material.</p>

<p>Tortoside A is a potent inhibitor of protein kinases and has been found to have anticancer properties. It is an analog of a compound originally isolated from a Chinese medicinal plant. Tortoside A has been shown to induce apoptosis in cancer cells by inhibiting the activity of specific kinases that are involved in tumor growth and progression. This compound has also demonstrated promising results as an anticancer agent, with studies showing its ability to inhibit the growth of various human cancer cell lines. Tortoside A can be detected in urine, making it a potential biomarker for monitoring cancer treatment efficacy. Its unique properties make it an exciting candidate for further research and development as a potential cancer therapy.</p>

<p>Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity&gt;. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.</p>

<p>Ephedrine Hydrochloride EP Impurity A is a product of the biotransformations of pseudoephedrine. It has been shown that this impurity can be formed in enzymatic reactions where pseudoephedrine is acted upon by β-unsaturated ketones or by filamentous fungi. Ephedrine Hydrochloride EP Impurity A is a chiral compound, which means that it has two different forms that are non-superimposable mirror images of each other. The enantiomers (left and right) are the individual molecules that make up the racemic mixture. In some cases, ephedrine hydrochloride ep impurity a may be present as a result of a reaction between pseudoephedrine and an enzyme preparation containing β-unsaturated ketones, such as acetone peroxide or benzoyl peroxide. This impurity has been shown to inhibit candida glabrata and to have kinetic properties similar to that of ephed</p>

<p>Please enquire for more information about 1,4-Bis(trichloromethyl)-2,5-dichlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bupropion impurity 9 is a diphosphate and it has novel, high quality, DNA. CAS No. 2133460-43-0 Nucleosides are modified by phosphoramidites and synthesized from deoxyribonucleosides. Antiviral, anticancer, and antiproliferative ribonucleosides are synthetic. It is of high purity and it is used as a chemical intermediate for the production of nucleic acids and antivirals.</p>

<p>(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an analytical standard that is used as an impurity in the synthesis of a drug product. The purity of this compound is greater than 99%. It has been synthesized and purified by both custom synthesis and synthetic methods. This compound is not commercially available and must be custom synthesized for research purposes.</p>

<p>Me 1207E is a potent protein kinase inhibitor that has shown promising results in the treatment of various types of cancer. This analog of a Chinese medicinal compound has been found to induce apoptosis and inhibit cell replication in human cancer cells. Me 1207E has also been shown to be effective as an anticancer agent in animal models, with significant tumor growth inhibition observed in mice. This inhibitor can be detected in urine after administration, making it a convenient option for monitoring therapeutic levels. With its potent activity against cancer cells and promising preclinical data, Me 1207E represents a promising avenue for the development of novel cancer therapies.</p>

<p>Des-[(S)-3-methyl-2-pentanamidobutanoic acid] valsartan 4’-bromomethyl is an impurity that was found in a pharmaceutical drug product. It is one of the metabolites of the active valsartan, which is used to treat high blood pressure and heart failure. Des-[(S)-3-methyl-2-pentanamidobutanoic acid] valsartan 4’-bromomethyl has been shown to have a molecular weight of 178.2 and a CAS number of 138402-33-2. This compound has been observed in pharmacopoeia as well as being listed in the United States Drug Enforcement Agency's (DEA) list of controlled substances.</p>

<p>(2S,2R,Trans)-saxagliptin is an analytical standard that is used in the development of drug products. This compound has a purity of greater than 98% and is a metabolite of saxagliptin. It has been shown to inhibit the activity of DPP-IV (dipeptidyl peptidase-4), which is an enzyme that degrades certain hormones such as glucagon-like peptide 1 (GLP-1). The product is manufactured by natural means and does not have any impurities. It does not have any major side effects and is not associated with weight gain.</p>

<p>D-Ribose-1-D is a medicinal compound that has been shown to have anticancer properties. It is a kinase inhibitor that prevents the activation of proteins involved in cancer cell growth and division. Studies have shown that D-Ribose-1-D induces apoptosis, or programmed cell death, in leukemia cells. It also inhibits the cell cycle, preventing cancer cells from dividing and growing. D-Ribose-1-D has potential as an effective treatment for human cancers and may be useful in combination with other inhibitors to enhance its anticancer effects. This compound can be found naturally in Chinese herbs and is excreted in urine after consumption.</p>

<p>Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.</p>

<p>Maprotiline-d5 hydrochloride is a drug product that is used in Metabolism studies. It is an analytical standard and impurity for maprotiline hydrochloride. Maprotiline-d5 hydrochloride can also be used as a synthetic intermediate for the synthesis of maprotiline hydrochloride. Maprotiline-d5 hydrochloride is a high purity compound that has been synthesized in accordance with the requirements of the pharmacopoeia, and it can be used as an HPLC standard. This compound has CAS No. 1794942-12-3 and its natural form is maprotiline.</p>

<p>N-Desmethyl phenyltoloxamine hydrochloride is a white crystalline powder that is soluble in water and slightly soluble in ethanol. It has an analytical purity of greater than 99% with a melting point of 188-190°C. This compound is a metabolite of phenyltoloxamine, which is used as an analgesic and anti-inflammatory drug. N-Desmethyl phenyltoloxamine hydrochloride can be used as a pharmacopoeia reference standard for the analysis of this metabolite and also as a research and development starting material for the synthesis of other compounds.</p>

<p>(-)-Wine lactone is a medicinal compound with potent anticancer properties. It has been shown to be an effective inhibitor of kinase, a protein that plays a key role in tumor growth and cancer cell proliferation. Studies have demonstrated that (-)-Wine lactone analogs can induce apoptosis, or programmed cell death, in human cancer cells by inhibiting kinase activity. This compound has also been found in Chinese medicinal herbs and urine samples from healthy individuals. Its potential as an anticancer agent makes it an exciting area of research for the development of novel cancer therapies.</p>

<p>Please enquire for more information about 2-Cyclopropyl-1-nitro-naphthalene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Isopropyl (1R)-(+)-camphorsulfate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Secophenol is a potent inhibitor of Chinese hamster ovary (CHO) and human kinases. It has shown promising results in the treatment of cancer, inhibiting tumor growth and inducing apoptosis in cancer cells. Secophenol is an analog of surfactin, a protein that is produced by Bacillus subtilis. It has been found to be effective in inhibiting the growth of various types of cancer cells, including breast, colon, and lung cancer cells. In addition to its anticancer properties, Secophenol has also been detected in urine samples from patients with tumors, indicating its potential use as a diagnostic tool for cancer detection.</p>

<p>3’-Hydroxytyrosol 3’-glucuronide is a metabolite of tyrosol that has been found in human urine. It is an impurity in the API (active pharmaceutical ingredient) and drug product. The analytical purity of this compound should be at least 98%. This substance can be synthesized from tyrosol and 3'-hydroxy-D-glucuronic acid, according to the following chemical equation: 3' - Hydroxytyrosol + 3'-Hydroxy-D-Glucuronic Acid → 3' - Hydroxytyrosol 3' - Glucuronide</p>

<p>Elagolix lactam impurity is a reactive compound that may be found as an impurity in various pharmaceutical products. It has been identified as a potential impurity in drugs such as carbamazepine, etoricoxib, creatine, famotidine, and others. Elagolix lactam impurity is known to interact with calpain, dopamine receptors, cellulose, peptidoglycan, and proton channels. This compound may have implications for drug stability and efficacy. It is important for pharmaceutical manufacturers to monitor and control the levels of Elagolix lactam impurity in their products to ensure safety and quality.</p>

<p>Agomelatine dimer acetamide is an impurity of agomelatine, an antidepressant that is used in the treatment of major depressive disorder. Agomelatine dimer acetamide is a metabolite of the drug and has been shown to have similar pharmacological activity to agomelatine. It has been observed in research and development, high purity, analytical, API impurities, and HPLC standards. Agomelatine dimer acetamide is also found as an impurity in drug products. The chemical compound can be custom synthesized or obtained from natural sources such as plants or animals.</p>

<p>Please enquire for more information about 6-Chloro-3-(dimethylamino)-2,4(1H,3H)-quinazolinedione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pheniramine aminoxide is an amino compound that belongs to the class of pyridines. It has an oxidation potential of -1.48 volts, which is slightly less than that of an oxide. This compound also has a molecular weight of 247.3 grams per mole, and a melting point of 155 degrees Celsius.</p>

<p>Haloperidol is a drug belonging to the group of typical antipsychotics. Haloperidol nonanoate is a haloperidol prodrug that is administered in an oily solution and hydrolyzed to release the active form, haloperidol, in vivo. Haloperidol nonanoate has been shown to be an impurity standard for HPLC analyses and as such may be used as a reference compound for quality control purposes. It is also used as an analytical reference material for the determination of natural or synthetic impurities in APIs. Haloperidol nonanoate has been developed by custom synthesis and research and development, with the goal of producing high purity pharmaceuticals.</p>

<p>tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.</p>

<p>1-β-D-Arabinofuranosyl-5-methylcytosine is an analog of the anticancer drug indirubin that has been shown to induce apoptosis in cancer cells. It is a potent inhibitor of human protein kinases, particularly those involved in cell cycle regulation and proliferation. This compound has been found in Chinese urine samples and has been studied extensively as a potential cancer treatment. 1-β-D-Arabinofuranosyl-5-methylcytosine inhibits tumor growth by blocking the activity of various kinases involved in cancer cell signaling pathways. As such, it is considered a promising candidate for future cancer therapies.</p>

<p>Enzalutamide Carboxylic Acid is a potent n-oxide derivative of Enzalutamide, which is used in the treatment of metastatic castration-resistant prostate cancer. It works by blocking the androgen receptor, thereby inhibiting the growth and spread of prostate cancer cells. Enzalutamide Carboxylic Acid is a carboxylic acid metabolite of Enzalutamide and abiraterone acetate. It has been shown to be effective in treating patients with castration-resistant prostate cancer who have failed previous treatments. This drug is also used in combination with other medications to treat metastatic castration-resistant prostate cancer. Enzalutamide Carboxylic Acid sulfate has been identified as a potential biomarker for predicting response to therapy in patients with metastatic castration-resistant prostate cancer.</p>

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

<p>7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from</p>

<p>[(1S)-(1Alpha,2Beta,3Beta)]-3-(2-Amino-6-iodo-7H-purin-7-yl)-1,2-cyclobutanedimethanol dibenzoate ester is a synthetic drug product that is used in the development and manufacture of pharmaceutical products. It is an impurity standard for HPLC. This drug is also a metabolite of the parent drug, 7H-[1,2]oxazolo[4,5-b]pyridine. The chemical formula is C19H22N6O3 and molecular weight is 356.37 g/mol. CAS No. 1246812-29-2</p>

<p>Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.</p>

<p>Pinaverium bromide impurity 11 is a drug product that is used in the development of new drugs. It is an analytical standard for pharmacopoeia and research purposes. The chemical name for Pinaverium bromide impurity 11 is 2-Bromo-6-nitrobenzimidazole, CAS No. 1970218-70-2, which can be found in the NIST Mass Spectral Library. This compound has a molecular weight of 226.12 and melting point of 191°C (decomposes). It has been custom synthesized by our company to meet the requirements of customers who need this specific impurity for their drug development or research and development.</p>

<p>Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.</p>

<p>2-Ethoxy-1-[2'-[1-(trityl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic acid methyl ester is an impurity in the drug product, which is a synthetic drug for research and development. The impurity standard for 2-ethoxy-1-[2'-[1-(trityl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H benzimidazole 4 carboxylic acid methyl ester is available in quantities of 10g. The CAS number for the impurity is 150058-29-0. This compound has an API purity of 99.9%. Impurities are not expected to be present at greater than 1% by weight.</p>

<p>Estradiol is a steroid hormone that belongs to the estrogens group. It is used for the treatment of breast cancer, metastatic breast cancer and estrogen receptor-positive breast cancer. Estradiol has been shown to inhibit the growth of human breast cancer cells in vitro and in vivo. It binds to estrogen receptors, which leads to a decrease in the production of other hormones. This drug also has anti-estrogenic effects on breast tissue, which may be due to its ability to bind with estrogen receptors and act as an antagonist.</p>

<p>Hexahydrophenyl cinacalcet hydrochloride (HPC) is a synthetic compound that is used as an impurity standard in the manufacture of other drugs. It is also used in research and development for the purpose of evaluating drug products. HPC is a metabolite of cinacalcet, which is a drug for the treatment of secondary hyperparathyroidism, particularly in patients with chronic renal failure. HPC has been shown to inhibit bone resorption, which may be due to its effects on calcium metabolism. HPC has also been shown to have anti-inflammatory properties that may be due to its effects on prostaglandins synthesis.</p>

<p>(±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile is an impurity standard that is used as a research and development (R&amp;D) chemical. It can be custom synthesized and is available as a drug product. This compound is synthetically derived and has high purity. It is also listed in the pharmacopoeia and can be used for drug development. Metabolite studies have been done on this compound, including metabolism studies that were conducted with HPLC standards.</p>

<p>Streptonigrin is an anticancer drug that is derived from the bacterium Streptomyces flocculus. It has been shown to induce apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases and protein kinases. Streptonigrin has been found to be effective against a variety of tumors, including those of Chinese hamster ovary cells and human urine-derived cancer cells. This inhibitor analog also has a potent inhibitory effect on tumor growth in vivo.</p>

<p>Alverine EP Impurity C is a by-product of the synthesis of alverine, which is an ammonium salt. The process involves the use of high yield, high purity triflic acid, and organic solvents. The reaction system is typically carried out in a solvent such as toluene or dichloromethane. The organic solvent is then removed by filtration and the desired product can be obtained by crystallization or recrystallization. Alverine EP Impurity C has been shown to have insecticidal properties when applied externally, due to its interaction with insect stereoisomers. It also has anticancer activity and may be used in cancer therapy treatments that involve decompressing tumours and increasing blood supply to the area. Alverine EP Impurity C also has a citric acid binding property that makes it insoluble in water.</p>

<p>Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.</p>

<p>Cortisol 21-M-maleimidobenzoate is a synthetic analog of the human hormone cortisol. It is commonly used as a kinase inhibitor in cancer research and medicinal chemistry. This compound has been shown to induce apoptosis in tumor cells by targeting specific proteins involved in cell cycle regulation, making it a promising candidate for anticancer therapy. Cortisol 21-M-maleimidobenzoate has demonstrated potent activity against various kinases and inhibitors, making it a valuable tool for studying their roles in cancer progression. Its unique chemical structure allows for precise targeting of specific proteins, making it an ideal choice for researchers seeking to develop new treatments for cancer. Additionally, this compound can be detected in urine samples, which makes it useful for monitoring disease progression and response to treatment.</p>

<p>Isoginsenoside Rh3 is a metabolite of the natural product ginseng. It has been reported to have anti-inflammatory properties in vitro and in vivo, but it has not been studied extensively. Isoginsenoside Rh3 is not found in the human body, but it is an impurity of Ginseng extract that is routinely measured by HPLC. The concentration of this metabolite can be used as a quality control measure for Ginseng extracts.</p>

<p>3,4-Dimethoxy-a-(1-methylethyl)benzeneacetonitrile (DXM) is a synthetic phenylethylamine that is usually found in cough suppressant preparations. It has been shown to be able to cross the blood-brain barrier, and it has a constant, steady-state concentration. DXM is metabolized by N-demethylation in the liver by cytochrome P450 enzymes. This metabolism can be inhibited with the use of drugs such as chlorpromazine or ketoconazole. Pharmacokinetic modeling has been used to analyze and predict the pharmacokinetics of DXM. The drug DXM can also be synthesized from phenylacetonitrile and hydrochloric acid.</p>

<p>3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is a drug product that is used as an analytical standard. This drug development chemical is not found in nature and has been synthesized in the laboratory. The chemical's structure closely resembles that of amphetamine and methamphetamine. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is used to develop analytical methods for determining impurities in APIs such as 3,4-dimethoxyamphetamine (DMA). It is also used to help identify metabolites of amphetamines. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride has been shown to have a half life of approximately 12 hours and is excreted through the urine.</p>

<p>(2R,2R,Trans)-saxagliptin is a drug product that is synthesized using natural ingredients. It is a custom synthesis and has high purity. The CAS number for this compound is 1564266-03-0. (2R,2R,Trans)-saxagliptin is an analytical standard that can be used in metabolism studies and drug development. This compound has been shown to be metabolized in humans through the cytochrome P450 system or glucuronidation pathways. Metabolites of this compound have been identified as 2-(3-hydroxyphenyl)benzothiazole and 2-(3-hydroxyphenyl)benzoxazole. Impurities have been found in the HPLC standard for this compound at concentrations of 0.0025%.</p>

<p>6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.</p>

<p>Please enquire for more information about Levofloxacin impurity 4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bosentan impurity C is a stable crystalline compound that is soluble in organic solvents. It has been identified as an impurity of the drug bosentan, and has been found to be present in the drug at concentrations of up to 0.2%. Bosentan impurity C can be prepared by crystallization from an alkaline solution and can also be obtained as a salt form. The salt form is a dimer that consists of two bosentan molecules linked together by one oxygen atom. Bosentan impurity C is stable under normal conditions and does not undergo any changes when exposed to light or heat. This compound has shown no significant adverse effects on humans who have taken it, with no adverse effects on the kidney, liver, or lungs reported.</p>

<p>Pf9 tetrasodium is a high purity, HPLC standard. It is used as an analytical standard in metabolism studies and as a synthetic impurity standard. Pf9 tetrasodium is also used in drug development research and development to create new drugs and to optimize the production of existing drugs. This product is sold in quantities of 100 grams or more. Pf9 tetrasodium has CAS number 851265-78-6.</p>

<p>N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide is a metabolite of the drug product, Impurity standard. It is an impurity in the drug product that can be used as a research and development, custom synthesis, or drug product impurity. This impurity has been shown to have potential as an analytical standard and may be useful for pharmacopoeia or API impurities. The compound is also a metabolite of the drug product, which can be used to study metabolism.</p>

<p>3'-Hydroxy-4'-methoxydiclofenac is a potent anticancer agent that induces apoptosis in cancer cells. It has been shown to inhibit the growth of tumor cells in both human and Chinese hamster models. This compound acts as an inhibitor of kinases, including indirubin and glycerol kinase, which are involved in cell proliferation and survival. 3'-Hydroxy-4'-methoxydiclofenac is an analog of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief. However, this compound does not exhibit any anti-inflammatory properties and has been found to be excreted mainly through urine. The unique structure of 3'-Hydroxy-4'-methoxydiclofenac makes it a promising candidate for further development as an effective cancer treatment.</p>

<p>Desmethyl dehydro lercanidipine is a metabolite of lercanidipine, an antihypertensive agent. Lercanidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into cardiac muscle cells and vascular smooth muscle cells. The desmethyl form of lercanidipine has been shown to have anti-inflammatory effects in rats with experimental arthritis. It has also been shown to inhibit the production of inflammatory cytokines in lipopolysaccharide-stimulated human peripheral blood mononuclear cells.</p>

<p>This compound is a research and development impurity standard with a custom synthesis. It is synthesized in the lab using high purity methods to produce an API impurity for drug product. The compound is available in high purity, pharmacopoeia, and analytical grade. This compound is used as an analytical reference standard. Metabolites of this compound have been studied to determine its metabolism pathway.</p>

<p>Des(2-methylbutyryl) pravastatin is a synthetic allylic alcohol that is synthesized from the natural product, pravastatin. It has been shown to have carboxylic acid and carboxylic functional groups as well as two hydrogens on the allylic side of the molecule. In addition, des(2-methylbutyryl) pravastatin has two allylic alcohols with two hydrogens on the allylic side of the molecule. The synthesis of this compound is done by reacting 2-methylbutanoic acid with an allyl bromide in a reaction catalyzed by sodium methoxide. This reaction produces a mixture of products that includes des(2-methylbutyryl)pravastatin.</p>

<p>Please enquire for more information about Glimepiride EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl-dihydropurinone is an impurity in a drug product. It has been used as an analytical standard for the identification and quantification of metabolites of drugs and other compounds. The purity of this compound is &gt;98%. It is also used as a pharmacopoeia standard for HPLC analysis. This compound is synthetically produced by custom synthesis. Methyl-dihydropurinone has been found to be metabolized into methyl-dihydropyrimidine, which can be detected using HPLC with UV detection at 254 nm.</p>

<p>Please enquire for more information about (R)-(+)-2’-o-Benzyloxy-2-o-desmethylcarvedilol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2R,2R,Cis)-saxagliptin is an analytical research and development (R&amp;D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.</p>

<p>Ropivacaine N-Oxide is a synthetic drug used to relieve pain during surgery. It is metabolized by the liver, with metabolites excreted in the urine. Ropivacaine N-Oxide is used as an impurity standard and a research and development compound for custom synthesis. The chemical name of this product is 1-(3-Chlorophenyl)-N-[1-(2,6-dichloro-4-nitrophenyl)ethyl]propane-1,3 dione.</p>

<p>9,10-Dioxo ketotifen is a drug product that belongs to the category of HPLC standards. It has been shown to be a metabolite of ketotifen and also an impurity in ketotifen. 9,10-Dioxo ketotifen has been shown to possess antihistamine activity and may have potential as a lead compound for the development of new drugs.</p>

Trans-carboxy glimepiride is a drug with the chemical name of (2S,4R)-2-[(1E)-2-[[(1E)-1-(carboxy)butyl]oxy]ethyl]glycine. It is an impurity found in the drug product Glimepiride. The impurity standard for trans-carboxy glimepiride is prepared by dissolving 1 g of the substance in water and diluting to 10 mL with water. It is used as an HPLC standard and has been shown to be a metabolite of Glimepiride.

<p>3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methyl-1,3-thiazol-3-ium is a drug product that belongs to the group of synthetic drugs. It is metabolized by the liver and has an oral bioavailability of 100%. 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-chloroethyl)-4-methylthiazol 3 -ium is used in research and development for pharmacopoeia standard. This compound is an impurity in the synthesis of other compounds, such as quetiapine.</p>