APIs for research and impurities

N-Desmethyl phenyltoloxamine hydrochloride is a white crystalline powder that is soluble in water and slightly soluble in ethanol. It has an analytical purity of greater than 99% with a melting point of 188-190°C. This compound is a metabolite of phenyltoloxamine, which is used as an analgesic and anti-inflammatory drug. N-Desmethyl phenyltoloxamine hydrochloride can be used as a pharmacopoeia reference standard for the analysis of this metabolite and also as a research and development starting material for the synthesis of other compounds.

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Atracurium cis-Quaternary Ester Benzensulfonate is an impurity standard used in the manufacture of atracurium. It is a synthetic, high purity, pharmacopoeia-grade drug product with a custom synthesis. Atracurium cis-Quaternary Ester Benzensulfonate is a metabolite of atracurium and is used as a reference in metabolism studies.

Olsalazine sodium impurity B is a synthetic compound that is used in the production of Olsalazine sodium. It is one of the metabolites of olsalazine and has been found to be more potent than olsalazine sodium. Olsalazine sodium impurity B is purified by HPLC and characterized by analytical methods such as UV, IR, melting point, NMR, and mass spectrometry. Impurity standard for this compound has not been established yet.

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4-Methyl-N-(5-methyl-2-pyridinyl)benzamide is a birefringent, crystalline compound that is soluble in organic solvents. This compound exhibits liquid crystal composition and can be synthesized by the reaction of 2,4-dimethylbenzoyl chloride with 5-methylpyrimidine. It has been used in the production of photolytic materials such as fluorine. 4-Methylbenzamide has been shown to have a skeleton that is composed of two fused pyridine rings and an amide group. The impurities found in this product are mainly methyl benzoate and methyl pyridine.

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Elagolix lactam impurity is a reactive compound that may be found as an impurity in various pharmaceutical products. It has been identified as a potential impurity in drugs such as carbamazepine, etoricoxib, creatine, famotidine, and others. Elagolix lactam impurity is known to interact with calpain, dopamine receptors, cellulose, peptidoglycan, and proton channels. This compound may have implications for drug stability and efficacy. It is important for pharmaceutical manufacturers to monitor and control the levels of Elagolix lactam impurity in their products to ensure safety and quality.

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4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a synthetic drug product that has been purified to high purity. This compound is used as an analytical standard and impurity in the development of drugs. 4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a metabolite of imidazole, which is a natural substance with unknown pharmacological activity. It has been found to be an impurity in the synthesis of various pharmaceuticals, including metronidazole and ampicillin. This product has not yet been evaluated for safety or efficacy in humans.

Propranolol hydrochloride is a non-selective beta-adrenergic blocker that blocks the effects of epinephrine, norepinephrine and dopamine. Propranolol hydrochloride has been shown to inhibit the activity of proximal tubules in the kidney, which may be due to its inhibition of chemical ionization. This drug also has antihypertensive activity and can be used for the treatment of cardiac disorders such as hypertension. Propranolol hydrochloride is a monoclonal antibody that is activated by nitro groups and binds with high affinity to multiple-reaction monitoring (MRM) transitions for protonated molecular ions at m/z 289, 296, 305, 313, 320, 328, 336 and 344. Propranolol hydrochloride also has vasodilatory effects on the papillary muscle which aids in regulating blood pressure by maintaining vascular resistance.

3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester is a compound that has been shown to have bactericidal activity against Gram-positive bacteria. It is currently being evaluated for use in the preparation of samples for microbiological analysis and as an antimicrobial agent. 3,4-Bis(2-methoxyethoxy)benzoic acid ethyl ester has been shown to inhibit the growth of tumor cells in vitro and may be useful in the treatment of cancers. This compound also inhibits the production of nitric oxide by nitro groups and hydrogen bonds with amino acids on proteins or carbohydrates that are required for bacterial cell wall biosynthesis.

Solifenacin impurity C is an impurity that is found in the drug product Solifenacin. It has been shown to be a natural metabolite and has been detected in human urine. Solifenacin impurity C is used as an analytical standard for HPLC analyses of solifenacin, and can also be used as a reference material for pharmacopoeia. The purity of this compound is 99%.

(R)-(+)-1,1,2-Triphenyl-1,2-ethanediol is a heterocyclic compound with a five-membered ring. It is chiral and has two stereogenic centers in its structure. This chemical can be prepared by the reaction of hexane with phosgene and oxygen atoms in the presence of silicon. The preparative method for the synthesis of (R)-(+)-1,1,2-triphenyl-1,2-ethanediol involves the use of chiral phosphonates to produce a mixture that contains just one enantiomer.

S-Clopidogrel N-methyl impurity is a Chinese medicinal compound that has been shown to have potent anticancer properties. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that regulate the growth and division of cancer cells. This compound has been found to induce apoptosis (cell death) in tumor cells, making it a promising candidate for cancer treatment. S-Clopidogrel N-methyl impurity is an analog of clopidogrel, a drug used to prevent blood clots. It can be detected in urine and has potential as a protein kinase inhibitor for the development of novel cancer therapies.

Scopolamine is a muscarinic antagonist that is used to prevent motion sickness and the nausea and vomiting associated with anesthesia. It is an ester of scopolamine with hydrobromic acid. Scopolamine hydrobromide has been shown to have similar effects on humans as it does on rats. It is absorbed through the skin and metabolized in the liver, where it is excreted in bile and eliminated through the urinary system. The elimination half-life of scopolamine hydrobromide in humans ranges from 1 to 3 hours, which means that its effects wear off after about three hours.

3’,4’-Dimethoxy flurbiprofen is a synthetic drug product with the molecular formula C17H18O3 and CAS No. 1346601-72-6. It is a metabolite of Ibuprofen, which is an active ingredient in many over-the-counter pain relievers. 3’,4’-Dimethoxy flurbiprofen is used in research and development as a standard for impurity testing and quality control. 3’,4’-Dimethoxy flurbiprofen has also been used as a pharmacopoeia to provide standards for HPLC analysis of ibuprofen metabolites.

2-Oxo clopidogrel hydrochloride is a drug product that belongs to the class of drugs called platelet aggregation inhibitors. It is a prodrug that is metabolized in vivo to form the active metabolite, 2-oxo-clopidogrel acid. This compound inhibits ADP and collagen-induced platelet aggregation by blocking the binding of adenosine diphosphate (ADP) to its receptor on the surface of platelets. The drug has been shown to have antiplatelet activity and inhibit thrombus formation in humans, as well as in animal models of atherosclerosis and coronary artery disease.