Enzyme Modulators
Enzyme modulators are compounds that can enhance or inhibit the activity of enzymes, thereby regulating the rate of biochemical reactions. These modulators play a critical role in controlling metabolic pathways, cell signaling, and various physiological processes. Enzyme modulators are widely used in research and drug development to study enzyme functions and to develop therapeutic agents. At CymitQuimica, we offer a comprehensive range of high-quality enzyme modulators to support your research in enzyme regulation and drug discovery.
Subcategories of "Enzyme Modulators"
Found 690 products for "Enzyme Modulators". Showing the first 500.
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(S)-Mephenytoin - Bio-X ™
CAS:(S)-Mephenytoin is a substrate of cytochrome P450 enzyme CYP2C19 (a hydroxylase). It is an effective anticonvulsant that improves control of seizures in patients. According to studies, the drug exhibits a genetic polymorphism in CYP2C19 that results in reduced metabolism in some individuals.Formula:C12H14N2O2Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:218.25 g/molPLX 4032
CAS:BRAF kinase inhibitor; antineoplasticFormula:C23H18ClF2N3O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:489.92 g/molKifunensine - Bio-X ™
CAS:Kifunensine is a small molecule inhibitor that was designed and synthesized to inhibit plant and animal α-mannosidase I. It is a potent and specific inhibitor with IC50 in nanomolar range. It inhibits the enzyme isoforms in Golgi apparatus (GMI) and endoplasmatic reticulum (ERMI). The compound prevents mannose trimming on glycoproteins and shifts the glycoform content from complex to oligomannose type. Used for the production of recombinant therapeutic glycoproteins with mannose rich N-linked glycans.Formula:C8H12N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:232.19 g/molBRD 6989
CAS:A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells. Modulatory action on inflammatory responses has therapeutic potential.Formula:C16H16N4Purity:Min. 95%Color and Shape:SolidMolecular weight:264.33 g/molMLi-2
CAS:A brain-penetrant inhibitor of leucin-rich repeat kinase 2 (LRRK2) with IC50 = 0.76 nM and anti-parkinsonian activity. Gain-of-function mutations in LRRK2 gene lead to increased familial and idiopathic risk of developing the disease. The inhibitors of the kinase activity have therapeutic potential against Parkinson’s disease.
Formula:C21H25N5O2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:379.46 g/molQ-VD-OPH
CAS:Inhibitor of caspases; broad spectrumFormula:C26H25F2N3O6Purity:Min. 98.00 Area-%Color and Shape:PowderMolecular weight:513.49 g/molVolitinib
CAS:Inhibitor of c-Met kinaseFormula:C17H15N9Purity:Min. 95%Color and Shape:White PowderMolecular weight:345.36 g/molSorafenib - Bio-X ™
CAS:Sorafenib is a drug that belongs to the class of multikinase inhibitors. It inhibits a number of kinases, including the Mcl-1 protein, which is involved in apoptosis along with blocking picolinic acid (PA), an endogenous metabolite involved in apoptosis signal transduction. Sorafenib also binds to epidermal growth factor receptor (EGFR) on the surface of cancer cells, inhibiting the production of proteins that are required for angiogenesis, thus blocking the formation of new blood vessels. Sorafenib may also inhibit P-glycoprotein (Pgp) activity. Overall, these cytotoxic effects give Sorafenib anti-tumor properties, inhibiting angiogenesis and cellular transformation, which are the two main processes of tumor growth and metastasis. Sorafenib has been shown to be effective against a range of solid tumors such as breast, prostate and lung cancers and is also used for the treatment of metastatic colorectal cancer and renal cell carcinoma. A combination therapy group found that sorafenib was more effective when used with interferon alfa-2b for the treatment of advanced renal cell carcinoma. Sorafenib also has the potential for drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Sorafenib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C21H16ClF3N4O3Purity:Min. 98%Color and Shape:PowderMolecular weight:464.82 g/molSeratrodast - Bio-X ™
CAS:Seratrodast is a thromboxane receptor antagonist that is used to treat asthma. However, this drug does not affect thrombus formation as other thromboxane synthase inhibitors do such as ozagrel.Formula:C22H26O4Purity:Min. 95%Color and Shape:PowderMolecular weight:354.44 g/molLumiracoxib - Bio-X ™
CAS:Controlled ProductLumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug that is used for the treatment of osteoarthritis. This drug inhibits prostaglandin synthesis via inhibition of COX-2.Formula:C15H13ClFNO2Purity:Min. 95%Color and Shape:PowderMolecular weight:293.72 g/molDovitinib base
CAS:Receptor tyrosine kinase inhibitor; anti-angiogenesis; anti-oncogenesisFormula:C21H21FN6OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:392.43 g/molAfatinib - Bio-X ™
CAS:Afatinib is a small molecule that inhibits the activity of cellular kinases that are involved in the progression of cancer. It is an Irreversible inhibitor of three members of the ErbB family. This molecule binds covalently to cysteine 797 residue in HER2 and blocks downstream cellular signalling which inhibits cellular growth and promotes apoptosis. It has been researched for the treatment of non-small cell lung cancer (NSCLC), breast cancer, pancreatic cancer and colorectal cancer.Formula:C24H25ClFN5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:485.94 g/molCamostat mesylate - Bio-X ™
CAS:Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. This drug has shown to reduce inflammation and pain. Studies have shown that Camostat has also inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.Formula:C20H22N4O5•CH4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:494.52 g/molLOXO-305
CAS:LOXO-305 is a small molecule inhibitor, which is a synthesized chemical compound designed to selectively target specific enzymes or pathways. Its source is rooted in medicinal chemistry and pharmacological research aimed at elucidating pathways involved in oncogenesis.
Formula:C22H21F4N5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:479.43 g/molR-(-)-Arundic acid
CAS:R-(-)-Arundic acid is a chiral compound, which is a derivative of arundic acid specifically designed for enantiomeric purity. It is sourced through synthetic organic chemistry processes, allowing for precise control over its stereochemistry. The mode of action of R-(-)-Arundic acid involves the inhibition of astrocyte activation by modulating the synthesis of certain cytokines and inflammatory mediators. This mechanism provides a neuroprotective effect, making it a valuable tool in the study of neurodegenerative diseases and brain injuries.
Formula:C11H22O2Purity:Min. 98 Area-%Color and Shape:Clear Viscous LiquidMolecular weight:186.29 g/molAnastrozole - Bio-X ™
CAS:Controlled ProductAnastrozole is a non-steroidal drug that belongs to the class of aromatase inhibitors. It inhibits the production of estrogen by blocking the conversion of androgens to estrogens in peripheral tissues. The drug has been shown to be effective in treating breast cancer in postmenopausal women. In vitro assays have shown that Anastrozole can inhibit tumor growth as well as induce apoptosis in human serum cells, which suggests that it may be effective against a variety of cancers.
Formula:C17H19N5Purity:Min. 95%Color and Shape:PowderMolecular weight:293.37 g/molBrivanib alaninate
CAS:VEGFR2 a tyrosine kinase receptor inhibitor; antineoplasticFormula:C22H24FN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:441.18123Ulixertinib
CAS:Inhibitor of ERK1 and ERK2 kinasesFormula:C21H22Cl2N4O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:433.33 g/molXMU MP 2
CAS:BRK tyrosine kinase (PTK6) inhibitor; anti-proliferative in breast cancer cells
Formula:C32H33F3N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:618.65 g/mol
