Enzyme Modulators
Enzyme modulators are compounds that can enhance or inhibit the activity of enzymes, thereby regulating the rate of biochemical reactions. These modulators play a critical role in controlling metabolic pathways, cell signaling, and various physiological processes. Enzyme modulators are widely used in research and drug development to study enzyme functions and to develop therapeutic agents. At CymitQuimica, we offer a comprehensive range of high-quality enzyme modulators to support your research in enzyme regulation and drug discovery.
Subcategories of "Enzyme Modulators"
Found 693 products of "Enzyme Modulators"
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GSK 1278863
CAS:Controlled Product<p>Inhibitor of HIF-prolyl hydroxylase isozymes PHD1, PHD2 and PHD3 with Ki in nanomolar range. The compound mimics the binding of N-oxalylglycine, chelates catalytic iron and prevents substrate entry into catalytic site. Inhibition of PHD enzymes leads to stabilization of hypoxia-induced factors HIF1α and HIF2α, followed by the production of erythropoietin (EPO).</p>Formula:C19H27N3O6Purity:(%) Min. 95%Color and Shape:PowderMolecular weight:393.43 g/molTAS 6417 hydrochloride
CAS:<p>TAS 6417 hydrochloride is a small-molecule inhibitor, which is synthesized via chemical processes in pharmaceutical research. It functions primarily as a potent and selective inhibitor of specific mutant forms of the epidermal growth factor receptor (EGFR). By targeting these EGFR mutations, TAS 6417 hydrochloride disrupts the signaling pathways that are crucial for the proliferation and survival of cancer cells.</p>Formula:C23H20N6O·HClPurity:Min. 95%Molecular weight:432.91 g/molGSK 2126458
CAS:<p>PI3K enzyme inhibitor; antineoplastic</p>Purity:Min. 98 Area-%Color and Shape:PowderRibociclib HCl
CAS:<p>Inhibitor of CDK4/6 serine/threonine kinases; antineoplastic</p>Formula:C23H30N8O·HClPurity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:471 g/molGSK 360A
CAS:<p>Inhibitor of prolyl 4-hydroxylase PHD</p>Formula:C17H17FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:348.33 g/molBLU 554
CAS:<p>A potent and selective covalent inhibitor of fibroblast growth factor receptor 4 (FGFR4). This receptor tyrosine kinase activates an oncogenic driver in hepatocellular carcinoma, the fibroblast growth factor 19 (FGF19). The FGFR4 inhibitor is therefore a promising candidate for the treatment of advanced liver cancer.</p>Formula:C24H24Cl2N4O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:503.38 g/molSacubitril calcium
CAS:<p>Inhibitor of metalloendopeptidase neprilysin</p>Formula:C24H29NO5•Ca0Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:431.53 g/molTipifarnib
CAS:<p>Tipifarnib is a farnesyltransferase inhibitor, which is a synthetic compound designed for experimental cancer treatment. It functions by targeting farnesyltransferase, an enzyme involved in the post-translational modification of proteins through the attachment of a farnesyl group to the protein's cysteine residue. This modification is crucial for the activity of several proteins, including those in the Ras signaling pathway, which is often dysregulated in cancer.</p>Formula:C27H22Cl2N4OPurity:Min. 95%Molecular weight:489.4 g/molSGX 523
CAS:<p>Inhibits c-MET tyrosine kinases</p>Formula:C18H13N7SPurity:Min. 95%Color and Shape:SolidMolecular weight:359.09531BYL 719
CAS:<p>A selective inhibitor of PI3Kα. Inhibits cancer cell proliferation by blocking the G0/G1 phase of the cell cycle. Anti-tumor effect of BYL 719 has been demonstrated in models of tumors with PI3KCA mutation and amplification in vivo. BYL 719 also suppresses tumor growth in pre-clinical models of osteosarcoma.</p>Formula:C19H22F3N5O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:441.47 g/molLinsitinib
CAS:<p>Dual IGF-1R and InsR kinase inhibitor; antineoplastic</p>Formula:C26H23N5OPurity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:421.49 g/molLetrozole - Bio-X ™
CAS:Controlled Product<p>Letrozole is an aromatase inhibitor drug that is used in the treatment of breast cancer in postmenopausal women. It is a non-steroidal type II inhibitor that blocks the active site and thus blocking the electron transfer chain of CYP19A1. As a result of this, the conversion of androgen to estrogen is inhibited.</p>Formula:C17H11N5Purity:Min. 95%Color and Shape:PowderMolecular weight:285.3 g/molPD 0325901
CAS:<p>A potent non ATP-competitive inhibitor of MAP/ERK kinase (MEK). Has anti-tumor activity in melanoma and papillary thyroid cancer cells with B-Raf mutations. Enhances generation and survival of induced pluripotent stem cells (iPSCs).</p>Formula:C16H14F3IN2O4Purity:Min. 95%Molecular weight:482.19 g/molTacrolimus monohydrate - Bio-X ™
CAS:<p>Tacrolimus is a calcineurin inhibitor drug that is used for the prevention of rejection after an organ transplant. This drug can also be used in the treatment of severe atopic dermatitis. Tacrolimus’ mechanism of action is not well known however it is understood that this drug inhibits T-lymphocyte activation by binding to an intracellular protein called FKBP-12. This drug also has anti-inflammatory properties.</p>Formula:C44H69NO12·H2OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:822.03 g/molCaspase Modulator I, 1541
CAS:<p>Caspase Modulator I, 1541 is a chemical compound designed to modulate the activity of caspases, a family of cysteine proteases critical in the regulation of apoptosis and inflammation. This product is synthesized through advanced chemical processes to ensure high specificity and potency. Its mode of action involves the selective inhibition and modulation of caspase activity, thereby influencing apoptotic pathways and immune responses.</p>Formula:C24H17N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:411.41 g/molGSK 626616
CAS:<p>Potent inhibitor of dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) with IC50 value of 0.7 nM. Elevates hemoglobin and platelet levels in anemic mice.</p>Formula:C18H10Cl2N4OSPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:401.27 g/mol(S)-Lisinopril - Bio-X ™
CAS:<p>Lisinopril is a drug that belongs to the group of angiotensin converting enzyme (ACE) inhibitors. It is used to treat hypertension, heart failure and myocardial infarction. Lisinopril binds to the active site of the ACE enzyme, preventing it from converting angiotensin I into angiotensin II.</p>Formula:C21H31N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:405.49 g/molTofacitinib
CAS:<p>JAK3 enzyme inhibitor</p>Formula:C16H20N6OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:312.37 g/molFloctafenine
CAS:<p>Nonsteroidal anti-inflammatory (NSAID)</p>Formula:C20H17F3N2O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:406.36 g/molLomeguatrib
CAS:<p>Inhibitor and pseudosubstrate of DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). It is used as a sensitizer for the treatment of advanced solid tumors, including prostate, colorectal and central nervous system malignancies. Lomeguatrib inhibits the repair mechanism of DNA damage induced by alkylating agents such as temozolomide, and therefore potentiates its anti-cancer effects.</p>Formula:C10H8BrN5OSPurity:Min. 95%Color and Shape:SolidMolecular weight:324.96329
