Endocrinología / Hormonas
Los inhibidores de endocrinología/hormonas son compuestos que bloquean la acción de las hormonas o interfieren con las vías de señalización hormonal. Estos inhibidores son esenciales para estudiar la regulación de los sistemas endocrinos y para desarrollar tratamientos para enfermedades relacionadas con las hormonas, como la diabetes, los trastornos tiroideos y los cánceres dependientes de hormonas. Al modular la actividad hormonal, estos inhibidores pueden ayudar a dilucidar las complejas interacciones dentro del sistema endocrino. En CymitQuimica, ofrecemos una amplia gama de inhibidores de endocrinología/hormonas de alta calidad para apoyar su investigación en endocrinología, farmacología y ciencias médicas.
Subcategorías de "Endocrinología / Hormonas"
- Receptor de andrógenos(229 productos)
- Anexina A(16 productos)
- Aromatasa(22 productos)
- Receptor de estrógeno / progestágeno(56 productos)
- GPR(1 productos)
- Receptor de glucocorticoides(166 productos)
- LHRH(1 productos)
- Receptor de opioides(326 productos)
- Receptor de prostaglandinas(122 productos)
- RAAS(90 productos)
- Reductasa(50 productos)
- Somatostatina(57 productos)
- Receptor de la hormona tiroidea (THR)(32 productos)
- Receptor de vasopresina(48 productos)
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Se han encontrado 3371 productos de "Endocrinología / Hormonas"
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J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Fórmula:C24H37N3O2Pureza:98%Forma y color:SolidPeso molecular:399.57PD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Fórmula:C37H61N5O7SPureza:98%Forma y color:SolidPeso molecular:719.97SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53L 365209
CAS:L 365209 is an oxytocin antagonist.Fórmula:C40H50N8O6Pureza:98%Forma y color:SolidPeso molecular:738.88Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Fórmula:C29H37N5O4S2Forma y color:SolidPeso molecular:583.77A4B17
A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.Fórmula:C14H7F4NSForma y color:SolidPeso molecular:297.27ER degrader 10
CAS:<p>ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 μM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.</p>Fórmula:C28H29F2NO3SForma y color:SolidPeso molecular:497.597Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Fórmula:C16H20N2O5Forma y color:SolidPeso molecular:320.34BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Fórmula:C28H37N3O5Pureza:98%Forma y color:SolidPeso molecular:495.61Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Fórmula:C39H42N4O9SForma y color:SolidPeso molecular:742.84LX1
CAS:LX1, an anti-prostate cancer compound, specifically targets the androgen receptor (AR), AR variants, and the steroidogenic enzyme AKR1C3. It inhibits AKR1C3's enzymatic function, decreases the conversion of androstenedione to testosterone, and reduces the expression of both AR and AR-V7, subsequently downregulating their target genes. Additionally, LX1 is effective in overcoming tumor cell resistance to Enzalutamide, and when combined with Enzalutamide, it further suppresses tumor growth.Fórmula:C22H15F6NO2Forma y color:SolidPeso molecular:439.35Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Fórmula:C29H25F4N5O2Forma y color:SolidPeso molecular:551.53FL442
CAS:FL442 is an Androgen Receptor (AR) modulator. This compound exhibits potent inhibitory effects in AR-dependent prostate cancer cells, showing similar suppression efficiency to the traditional antiandrogen drugs Bicalutamide and Enzalutamide. It also maintains antiandrogen activity against the Enzalutamide-resistant AR mutant F876L. The pharmacokinetic properties of FL442 in mice reveal a longer half-life (8 hours), excellent targeting (prostate tissue), and metabolic stability. Additionally, it is effective at inhibiting LNCaP tumor growth at low plasma concentrations (30 ng/mL).Fórmula:C15H13F3N2OForma y color:SolidPeso molecular:294.27LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Fórmula:C30H31NO5SForma y color:SolidPeso molecular:517.64(+)-JJ-74-138
CAS:(+)-JJ-74-138 is a novel non-competitive androgen receptor (AR) antagonist capable of inhibiting enzalutamide-resistant castration-resistant prostate cancer (CRPC).Fórmula:C22H22F8N2OSForma y color:SolidPeso molecular:514.48Androgen receptor ligand 1
CAS:Androgen receptorligand 1 is a ligand for the androgen receptor (AR). It interacts with the CRBN E3 ligase via a linker to form an AR-PROTAC degrader. This compound is useful in prostate cancer research.Fórmula:C19H16F4N2OForma y color:SolidPeso molecular:364.34OT-R agonist 1 TFA
CAS:OT-R agonist 1 TFA (compound 5) is an oxytocin receptor (OT-R) agonist with an EC50 value of 0.39 nM. It exhibits V1A antagonist activity, with an EC50 value of 2432 nM, and can be utilized in studies related to central nervous system diseases.Fórmula:C37H40F3N7O7SForma y color:SolidPeso molecular:783.82L162389
CAS:L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.Fórmula:C31H38N4O4SPureza:99.11% - 99.57%Forma y color:SolidPeso molecular:562.72Cort108297
CAS:Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Fórmula:C26H25F4N3O3SPureza:98.36% - 99.94%Forma y color:SolidPeso molecular:535.55Ref: TM-T15000
1mg274,00€5mg622,00€10mg908,00€25mg1.415,00€50mg1.882,00€100mg2.745,00€1mL*10mM (DMSO)747,00€
