Endocrinología / Hormonas
Los inhibidores de endocrinología/hormonas son compuestos que bloquean la acción de las hormonas o interfieren con las vías de señalización hormonal. Estos inhibidores son esenciales para estudiar la regulación de los sistemas endocrinos y para desarrollar tratamientos para enfermedades relacionadas con las hormonas, como la diabetes, los trastornos tiroideos y los cánceres dependientes de hormonas. Al modular la actividad hormonal, estos inhibidores pueden ayudar a dilucidar las complejas interacciones dentro del sistema endocrino. En CymitQuimica, ofrecemos una amplia gama de inhibidores de endocrinología/hormonas de alta calidad para apoyar su investigación en endocrinología, farmacología y ciencias médicas.
Subcategorías de "Endocrinología / Hormonas"
- Receptor de andrógenos(229 productos)
- Anexina A(16 productos)
- Aromatasa(22 productos)
- Receptor de estrógeno / progestágeno(64 productos)
- GPR(1 productos)
- Receptor de glucocorticoides(165 productos)
- LHRH(2 productos)
- Receptor de opioides(325 productos)
- Receptor de prostaglandinas(122 productos)
- RAAS(86 productos)
- Reductasa(51 productos)
- Somatostatina(57 productos)
- Receptor de la hormona tiroidea (THR)(32 productos)
- Receptor de vasopresina(48 productos)
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Se han encontrado 3369 productos de "Endocrinología / Hormonas"
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LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Fórmula:C30H31NO5SForma y color:SolidPeso molecular:517.64EN171
CAS:EN171, a covalent ligand, selectively binds to C38 and C96 on 14-3-3, intensifying 14-3-3's interactions with ERα, YAP, and TAZ. This action impairs both estrogen receptor and Hippo pathway transcriptional activities. Beyond serving as a molecular glue to augment native protein interactions, EN171 also functions as a covalent recruiter for 14-3-3 in heterobifunctional molecules. This facilitates the sequestration of nuclear neo-substrates, such as BRD4 and BLC6, into the cytosol.Fórmula:C17H22N2OForma y color:SolidPeso molecular:270.37Sunobinop
CAS:Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Fórmula:C26H33N3O3Forma y color:SolidPeso molecular:435.56CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Fórmula:C28H27FN4O4Forma y color:SolidPeso molecular:502.54MK-6913
CAS:MK-6913 is a potent and selective agonist of estrogen receptor β.Fórmula:C25H27N3O2Pureza:98%Forma y color:SolidPeso molecular:401.5Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Fórmula:C30H40Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:531.56MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Fórmula:C19H25NaO5PPureza:98%Forma y color:SolidPeso molecular:387.36Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Fórmula:C40H45Cl2N3O6Pureza:98.17% - 99.88%Forma y color:SolidPeso molecular:734.71Ref: TM-T12241
1mg38,00€5mg85,00€10mg120,00€25mg235,00€50mg409,00€100mg652,00€200mg908,00€1mL*10mM (DMSO)124,00€AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Fórmula:C29H32N4O5S2Pureza:99.73%Forma y color:SolidPeso molecular:580.72Urotensin-II receptor antagonist-1
CAS:Urotensin-II receptor antagonist-1 (compound 1) is a human Urotensin II receptor antagonist with low oral bioavailability (F=0-3% in rats) and a Ki of 16 nM in HEK293 cells expressing human recombinant UT receptors. It inhibits cytochrome P450 enzymes (IC50=0.75 μM for CYP2D6; 1.4 μM for CYP3A4), suppresses κ opioid receptors (EC50=3.2 μM), and targets cardiac sodium channels (Ki=2.5 μM).Fórmula:C25H31Cl2N3OForma y color:SolidPeso molecular:460.439DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Fórmula:C32H33Cl2FN4O3Forma y color:SolidPeso molecular:611.53AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Fórmula:C29H37N5O4S2Forma y color:SolidPeso molecular:583.77A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Fórmula:C44H74N4O8Pureza:98%Forma y color:SolidPeso molecular:787.08Naltrindole 5′-isothiocyanate
CAS:Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.Fórmula:C27H25N3O3SForma y color:SolidPeso molecular:471.571rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFórmula:C24H30Cl3NOPureza:98%Forma y color:SolidPeso molecular:454.86Estrogen receptor antagonist 6
CAS:Estrogen receptor antagonist 6 is a potent blocker of estrogen signaling, regulating various biological effects. (Compound 166)Fórmula:C25H31F3N2O3Forma y color:SolidPeso molecular:464.52AP5
CAS:AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Fórmula:C28H28FNO4Pureza:98%Forma y color:SolidPeso molecular:461.52JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Fórmula:C28H41Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:538.55TRβ agonist 1
CAS:TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.Fórmula:C29H25FN2O8Forma y color:SolidPeso molecular:548.52ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Fórmula:C17H21N5OForma y color:SolidPeso molecular:311.38
