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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • Logo de CymitQuimica
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    α-Glucosidase-IN-19

    <p>Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.</p>
    Fórmula:C31H25NOS
    Forma y color:Solid
    Peso molecular:459.6

    Ref: TM-T62891

  • Etoricoxib N1'-oxide
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    Etoricoxib N1'-oxide

    CAS:
    <p>EtoricoxibN1'-oxide is a metabolite of Etoricoxib. It does not inhibit COX-1 and does not significantly inhibit COX-2.</p>
    Fórmula:C18H15ClN2O3S
    Forma y color:Solid
    Peso molecular:374.841

    Ref: TM-TYD-02100

  • IDO1 ligand-1
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    IDO1 ligand-1

    CAS:
    <p>IDO1ligand-1 is the target protein ligand for PROTAC NU227326, which is utilized for degrading IDO1.</p>
    Fórmula:C29H34FN3O2
    Forma y color:Solid
    Peso molecular:475.598

    Ref: TM-T206464

  • PSI-7410
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    PSI-7410

    CAS:
    <p>PSI-7410 is a metabolite of PSI-7851. PSI-7851 acts as an inhibitor of the HCV non-structural protein 5B (NS5B) and exhibits antiviral properties.</p>
    Fórmula:C10H15FN2O11P2
    Forma y color:Solid
    Peso molecular:420.179

    Ref: TM-TYD-02031

  • RORγt/DHODH-IN-1
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    RORγt/DHODH-IN-1

    CAS:
    RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant
    Fórmula:C24H26ClF6N3O3S
    Forma y color:Solid
    Peso molecular:585.99

    Ref: TM-T64145

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    RORγt/DHODH-IN-3

    <p>RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 has</p>
    Fórmula:C24H26ClF6N3O3S
    Forma y color:Solid
    Peso molecular:585.99

    Ref: TM-T64146

  • Logo de CymitQuimica
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    Indoluidin E

    <p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>
    Fórmula:C28H30N4O2
    Forma y color:Solid
    Peso molecular:454.56

    Ref: TM-T62802

  • Lapaquistat
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    Lapaquistat

    CAS:
    <p>Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.</p>
    Fórmula:C31H39ClN2O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:603.1

    Ref: TM-T15710

  • Logo de CymitQuimica
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    GSK2945 hydrochloride

    <p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>
    Fórmula:C20H19Cl3N2O2S
    Forma y color:Solid
    Peso molecular:457.8

    Ref: TM-T62852

  • Logo de CymitQuimica
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    LXR agonist 2

    <p>LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR.</p>
    Fórmula:C35H40ClN3O3
    Forma y color:Solid
    Peso molecular:586.16

    Ref: TM-T64148

  • Logo de CymitQuimica
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    PDHK-IN-3

    <p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>
    Fórmula:C17H16N2O2
    Forma y color:Solid
    Peso molecular:280.32

    Ref: TM-T60527

  • Logo de CymitQuimica
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    Carbonic anhydrase inhibitor 10

    <p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>
    Fórmula:C14H17N5O3S
    Forma y color:Solid
    Peso molecular:335.38

    Ref: TM-T61032

  • SHP2 IN-1
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    SHP2 IN-1

    CAS:
    <p>SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).</p>
    Fórmula:C18H22Cl2N6OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:441.38

    Ref: TM-T12903

  • T-3764518
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    T-3764518

    CAS:
    <p>T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).</p>
    Fórmula:C20H17F6N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:473.37

    Ref: TM-T13054

  • 11β-HSD2-IN-2
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    11β-HSD2-IN-2

    CAS:
    <p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>
    Fórmula:C22H21NO2
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:331.41

    Ref: TM-T85382

  • Fluopimomide
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    Fluopimomide

    CAS:
    <p>Fluopimomide (LH2010A), a powerful insecticide, is extensively utilized in the control of agricultural pests. It adversely affects the growth, locomotor behavior, reproduction, and lifespan of nematodes. Concurrently, it leads to increased production of reactive oxygen species (ROS), accumulation of lipids and lipofuscins, as well as a rise in malondialdehyde content. Additionally, Fluopimomide inhibits the antioxidant system of nematodes.</p>
    Fórmula:C15H8ClF7N2O2
    Forma y color:Solid
    Peso molecular:416.68

    Ref: TM-T201688

  • Logo de CymitQuimica
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    PTP1B-IN-18

    <p>PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.</p>
    Fórmula:C26H19N3O4S
    Forma y color:Solid
    Peso molecular:469.51

    Ref: TM-T63022

  • Logo de CymitQuimica
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    Vimirogant hydrochloride

    <p>Vimirogant (VTP-43742) HCl: Oral, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM), &gt;1000x selectivity over RORα/β, targets Th17, not Th1/2/Treg.</p>
    Fórmula:C27H36ClF3N4O3S
    Forma y color:Solid
    Peso molecular:588.21487

    Ref: TM-T64300

  • BMS-185354
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    BMS-185354

    CAS:
    <p>BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.</p>
    Fórmula:C26H27NO3
    Forma y color:Solid
    Peso molecular:401.497

    Ref: TM-T205728

  • FXIa-IN-6
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    FXIa-IN-6

    CAS:
    <p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>
    Fórmula:C31H29ClF2N4O4
    Forma y color:Solid
    Peso molecular:595.04

    Ref: TM-T39035