Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(42 productos)
- Aminopeptidasa(76 productos)
- CETP(20 productos)
- Anhídrido carbónico(196 productos)
- Caseína quinasa(138 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(302 productos)
- FAAH(64 productos)
- FXR(62 productos)
- Factor Xa(85 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(226 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(57 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(34 productos)
- Hidroxilasa(36 productos)
- IDO(84 productos)
- LDL(7 productos)
- Lipasa(107 productos)
- Lípido(61 productos)
- Lipoxigenasa(134 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(169 productos)
- PED(1 productos)
- PKM(17 productos)
- PPAR(170 productos)
- Fosfolipasa(86 productos)
- ROR(47 productos)
- Receptor de retinoides(22 productos)
- SGK(10 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(45 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9181 productos de "Metabolismo"
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HSD17B13-IN-19
CAS:HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].Fórmula:C23H23FN2O4SForma y color:SolidPeso molecular:442.5SCP1-IN-1
CAS:SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.Fórmula:C20H19F3N2O7S2Pureza:99.53%Forma y color:SoildPeso molecular:520.5Ref: TM-T60077
1mg49,00€5mg104,00€10mg169,00€25mg311,00€50mg472,00€100mg707,00€1mL*10mM (DMSO)119,00€ZK168281
CAS:ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.Fórmula:C32H46O5Pureza:98%Forma y color:SolidPeso molecular:510.70Diacylglycerol acyltransferase inhibitor-1
CAS:Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.Fórmula:C21H23N5O2Pureza:98%Forma y color:SolidPeso molecular:377.44hDHODH-IN-10
hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.Fórmula:C21H15ClF4N2O4Forma y color:SolidPeso molecular:470.8ATUX-1215
CAS:ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70,Fórmula:C27H24F5NO4SForma y color:SolidPeso molecular:553.54Desmonomethylpromazine
CAS:Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.Fórmula:C16H18N2SForma y color:SolidPeso molecular:270.39Clopidogrel-β-D-glucuronide
CAS:Clopidogrel-β-D-glucuronide is a metabolite of Clopidogrel. It directly interacts with the CYP2C8 enzyme and strongly inhibits the hepatic enzyme CYP2C8.Fórmula:C21H22ClNO8SForma y color:SolidPeso molecular:483.919L 671776
CAS:L 671776 is an inositol monophosphatase inhibitor.Fórmula:C23H32O5Pureza:98%Forma y color:SolidPeso molecular:388.5PFM046
CAS:PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.Fórmula:C29H42O2Forma y color:SolidPeso molecular:422.643Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Fórmula:C15H17N3O3SForma y color:SolidPeso molecular:319.38Mutant IDH1-IN-3
CAS:Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor targeting the mutant isocitrate dehydrogenase 1 (IDH1), with an IC50 of 13 nM for R132HIDH1. It effectively suppresses the production of D-2-hydroxyglutarate (2HG) in cells and is applicable for research in oncology.Fórmula:C22H30N4OForma y color:SolidPeso molecular:366.5PDE4-IN-5
PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.464-(4-Bromophenyl)-4-hydroxypiperidine
CAS:4-(4-Bromophenyl)-4-hydroxypiperidine (BPHP) is a metabolite of Bromperidol (BRO), produced through the N-dealkylation of BRO.
Fórmula:C11H14BrNOForma y color:SolidPeso molecular:256.139Benfooxythiamine
CAS:Benfooxythiamine is a transketolase (TKT) inhibitor that suppresses SARS-CoV-2 replication and enhances the activity of the glycolysis inhibitor 2DG. It exhibits antiviral properties.
Fórmula:C19H22N3O7PSForma y color:SolidPeso molecular:467.4334-Hydroxyclonidine
CAS:4-Hydroxyclonidine is a metabolite of Clonidine. It is equally effective as Clonidine in displacing labeled Clonidine from antibodies.Fórmula:C9H9Cl2N3OForma y color:SolidPeso molecular:246.093FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Forma y color:SolidGT-02216
CAS:GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.Fórmula:C22H23N5O2Forma y color:SolidPeso molecular:389.45Atorvastatin 3-Deoxyhept-2E-Enoic Acid
CAS:Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.Fórmula:C33H33FN2O4Pureza:98%Forma y color:SolidPeso molecular:540.62DRX-065
CAS:DRX-065, a deuterated R-enantiomer of pioglitazone, treats NASH without PPARγ weight gain issues.Fórmula:C19H20N2O3SForma y color:SolidPeso molecular:357.45
