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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 9182 productos de "Metabolismo"

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  • Magnesium ionophore III

    CAS:
    Magnesium ionophore III (ETH 4030) is an ion carrier that regulates intracellular magnesium ion concentrations. It enhances cellular functions and metabolic activities by increasing the permeability of cell membranes to magnesium ions. Additionally, Magnesium ionophore III is utilized in research to explore the significance of magnesium ions in biological processes and their impact on cellular physiology.
    Fórmula:C30H58N4O4
    Forma y color:Solid
    Peso molecular:538.81

    Ref: TM-T201134

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  • Casein kinase 1δ-IN-19

    CAS:

    Casein kinase1δ-IN-19 (compound 492) is a potent inhibitor of casein kinase 1δ. It is utilized in research related to neurodegenerative disorders, such as Alzheimer's disease.

    Fórmula:C21H19N5O3
    Forma y color:Solid
    Peso molecular:389.407

    Ref: TM-T204696

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  • 6′SLN

    CAS:
    6′SLN is a characteristic glycan found on the surface of cancer-related extracellular vesicles (EVs) and serves as the primary form of protein glycosylation within EVs. Additionally, 6′SLN, a derivative of sialic acid, interacts with hemagglutinins (HAs) from both human and avian influenza strains, making it relevant in the study of anti-influenza drugs.
    Fórmula:C25H42N2O19
    Forma y color:Solid
    Peso molecular:674.6

    Ref: TM-T200406

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  • ERAP1 modulator-2

    CAS:

    ERAP1 modulator-2 (compound 10) is a potent ERAP1 inhibitor with an IC50 value of less than 100 nM.

    Fórmula:C22H25F3N2O4S
    Forma y color:Solid
    Peso molecular:470.505

    Ref: TM-T204335

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  • Dopaminechrome

    CAS:

    Dopaminechrome (DACHR) is an oxidation product of dopamine that promotes the generation of H2O2 at mitochondrial complex I in the brain in a concentration- and respiration-dependent manner. It possesses neurotoxic properties and can be utilized in Parkinson's disease research.

    Fórmula:C8H7NO2
    Forma y color:Solid
    Peso molecular:149.147

    Ref: TM-T204340

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  • 1-Stearoyl-sn-glycerol 3-phosphate sodium

    CAS:
    1-Stearoyl-sn-glycerol 3-phosphate sodium, a biologically active phospholipid, plays a crucial role in regulating cell motility, proliferation, invasion, survival, and the production of growth factors through interactions with G protein-coupled receptors (GPCR). Synthesized during the formation of membrane phospholipids, this compound typically has a low plasma concentration (approximately 100nM) and originates from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its distinctive structure features stearic acid at the sn-1 position and a hydroxyl group at the sn-2 position.
    Fórmula:C21H42NaO7P
    Forma y color:Solid
    Peso molecular:460.52

    Ref: TM-T201300

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  • DC360

    CAS:

    DC360 is a synthetic analog of all-trans retinoic acid (ATRA) that can induce the expression of RARβ. It is useful for studies characterizing the retinoic acid signaling pathway.

    Fórmula:C23H23NO2
    Forma y color:Solid
    Peso molecular:345.434

    Ref: TM-T204562

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  • DOCP

    CAS:
    DOCP (2-((2,3-Bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate) is a lipid characterized by an opposite charge orientation compared to traditional phosphatidylcholine (PC) lipids, featuring quaternary ammonium near the bilayer interface and phosphate groups projecting into the aqueous environment. This unique structure of iPC lipids presents an excellent opportunity to investigate the biophysical characteristics and biological activities influenced by the reversal of surface charges on bilayers.
    Fórmula:C43H82NO8P
    Forma y color:Solid
    Peso molecular:772.09

    Ref: TM-T201007

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  • 4-MDM

    CAS:
    4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.
    Fórmula:C14H14O
    Forma y color:Solid
    Peso molecular:198.26

    Ref: TM-T204132

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  • IDO1-IN-25

    CAS:
    IDO1-IN-25, a dual inhibitor of IDO1/TDO2, showcases IC50 values of 0.17 μM for IDO1 and 3.2 μM for TDO2. It effectively suppresses NO production in RAW264.7 cells following stimulation with lipopolysaccharide (LPS). Additionally, IDO1-IN-25 demonstrates anti-inflammatory properties in a mouse ear edema model of acute inflammation induced by croton oil.
    Fórmula:C14H8Cl3NO2S
    Forma y color:Solid
    Peso molecular:360.64

    Ref: TM-T200055

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    1.444,00€
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    1.882,00€
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    2.375,00€
  • LTA4H-IN-2

    CAS:
    LTA4H-IN-2 (compound (S)-2) acts as an orally active inhibitor targeting Leukotriene A4 Hydrolase, exhibiting potent activity with an IC 50 of less than 3 nM [1].
    Fórmula:C20H19FN6O2
    Forma y color:Solid
    Peso molecular:394.4

    Ref: TM-T86827

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  • CGS 24592

    CAS:
    CGS-24592 is an orally active, selective, and potent inhibitor of neutral endopeptidase 24.11 (NEP), with an IC50 value of 1.6 nmol/L. It reduces the degradation of atrial natriuretic peptide (ANP), thereby increasing plasma ANP concentration and lowering blood pressure. CGS-24592 shows potential for research in cardiovascular diseases such as hypertension and congestive heart failure.
    Fórmula:C19H23N2O6P
    Forma y color:Solid
    Peso molecular:406.37

    Ref: TM-T206087

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  • Bestatin methyl ester

    CAS:
    Bestatin methyl ester (600, 900 µM; 24 h) inhibits spore cell differentiation in Dictyostelium discoideum.
    Fórmula:C17H26N2O4
    Forma y color:Solid
    Peso molecular:322.4

    Ref: TM-T88754

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  • Quinapril

    CAS:
    Quinapril is an orally active, non-peptide, and non-thiol angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II in both plasma and tissues. Upon enzymatic hydrolysis, Quinapril is converted into the pharmacologically active Quinaprilat and is effective in hypertension models.
    Fórmula:C25H30N2O5
    Forma y color:Solid
    Peso molecular:438.516

    Ref: TM-T204362

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  • (±)-HIP-B

    CAS:
    (±)-HIP-B is an excitatory amino acid transporter blocker.
    Fórmula:C6H8N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:172.14

    Ref: TM-T22480

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  • m-APTA

    CAS:
    m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP). It can be converted into adenine, which is a crucial step in shielding normal cells from the toxicity of nucleobase analogs (NBA). m-APTA holds potential for research in MTAP-deficient cancers.
    Fórmula:C16H18N6O3S
    Forma y color:Solid
    Peso molecular:374.418

    Ref: TM-T206811

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  • PRL3-CNNM4 interaction-IN-1

    CAS:
    PRL3-CNNM4 interaction-IN-1 (Compound C28d52) is an inhibitor of the PRL3-CNNM4 interaction that also suppresses CNNM inhibition mediated by PRL. This compound exhibits favorable pharmacokinetic and drug metabolism properties.
    Fórmula:C8H8O2S
    Forma y color:Solid
    Peso molecular:168.21

    Ref: TM-T200840

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  • CK1δ-IN-3

    CAS:
    CK1δ-IN-3 (compound 376) is a CK1δ (casein kinase 1δ) inhibitor that can be used to study neurodegenerative diseases such as Alzheimer's disease.
    Fórmula:C24H19N3O2S
    Pureza:99.27%
    Forma y color:Solid
    Peso molecular:413.49

    Ref: TM-T204344

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    185,00€
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    459,00€
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    657,00€
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    1.026,00€
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    1.415,00€
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    1.872,00€
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    2.555,00€
  • L 671776

    CAS:
    L 671776 is an inositol monophosphatase inhibitor.
    Fórmula:C23H32O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:388.5

    Ref: TM-T24326

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  • Carbonic anhydrase inhibitor 4


    CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.
    Fórmula:C21H18N2O4S
    Forma y color:Solid
    Peso molecular:394.44

    Ref: TM-T61829

    25mg
    1.444,00€
    50mg
    1.882,00€
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    2.375,00€