Tirosina quinasa / adaptadores
Los inhibidores de tirosina quinasa y adaptadores son compuestos que se dirigen a las tirosina quinasas y sus proteínas adaptadoras asociadas, las cuales desempeñan roles cruciales en la señalización celular, el crecimiento y la diferenciación. Estos inhibidores son herramientas esenciales en la investigación del cáncer, ya que muchas tirosina quinasas están involucradas en las vías de señalización que impulsan el crecimiento tumoral y la metástasis. Al inhibir las tirosina quinasas, estos compuestos pueden bloquear cascadas de señalización críticas, ofreciendo potenciales estrategias terapéuticas para varios tipos de cáncer y otras enfermedades que implican una señalización celular anormal. En CymitQuimica, ofrecemos una amplia gama de inhibidores de tirosina quinasa y adaptadores de alta calidad para apoyar su investigación en oncología, biología molecular y desarrollo de terapias dirigidas.
Subcategorías de "Tirosina quinasa / adaptadores"
- ALK(116 productos)
- CSF-1R(42 productos)
- EGFR(572 productos)
- Receptor de efrina(23 productos)
- FLT(91 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(169 productos)
- HER(5 productos)
- Hck(3 productos)
- IGF-1R(92 productos)
- PDGFR(126 productos)
- PYK2(7 productos)
- Src(80 productos)
- Receptor TAM(32 productos)
- Tie-2(21 productos)
- Receptor de Trk(59 productos)
- Tirosina quinasas(26 productos)
- VEGFR(262 productos)
- c-Fms(108 productos)
- c-Kit(102 productos)
- c-Met / HGFR(129 productos)
- c-RET(51 productos)
Mostrar 13 subcategorías más
Se han encontrado 1342 productos de "Tirosina quinasa / adaptadores"
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Pazopanib
CAS:Fórmula:C21H23N7O2SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:437.52Vandetanib
CAS:Fórmula:C22H24BrFN4O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:475.36BAY-826
CAS:<p>BAY-826 is a novel, potent and selective TIE-2 inhibitor that inhibits TIE-2 phosphorylation and can be used to study tumors.</p>Fórmula:C26H19F5N6OSPureza:98% - 99.28%Forma y color:SolidPeso molecular:558.53Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:375.41PD 173074
CAS:Fórmula:C28H41N7O3Pureza:>95.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:523.68Cediranib
CAS:Fórmula:C25H27FN4O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:450.51Motesanib
CAS:Fórmula:C22H23N5OPureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:373.46Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(T)(HPLC)Forma y color:White to Yellow to Yellow green powder to crystalPeso molecular:539.64SB-525334
CAS:Fórmula:C21H21N5Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:343.43Sunitinib Malate
CAS:Fórmula:C22H27FN4O2·C4H6O5Pureza:>98.0%(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:532.57Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76trans-Pralsetinib
CAS:<p>trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).</p>Fórmula:C27H32FN9O2Pureza:98%Forma y color:SolidPeso molecular:533.6SU 5416
CAS:Fórmula:C15H14N2OPureza:>98.0%(T)(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:238.29PLX647
CAS:<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Fórmula:C21H17F3N4Pureza:99.38%Forma y color:SolidPeso molecular:382.38PD-161570
CAS:Fórmula:C26H35Cl2N7OPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:532.51SU14813 maleate
CAS:<p>SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).</p>Fórmula:C27H31FN4O8Pureza:98%Forma y color:SolidPeso molecular:558.56Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:589.72N-Desethyl Sunitinib
CAS:<p>N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,</p>Fórmula:C20H23FN4O2Pureza:98%Forma y color:SolidPeso molecular:370.42PF-06737007
CAS:PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).Fórmula:C25H28F4N2O6Pureza:98%Forma y color:SolidPeso molecular:528.49Osimertinib dimesylate
CAS:Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60Mavelertinib
CAS:Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Fórmula:C21H20ClF3N4O3SPureza:99.82%Forma y color:SolidPeso molecular:500.92Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:275.13Cediranib Maleate
CAS:Fórmula:C25H27FN4O3·C4H4O4Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:566.59EGFR Protein, Human, Recombinant (His & Avi)
<p>EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.Pazopanib Hydrochloride
CAS:Fórmula:C21H23N7O2S·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:473.98EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)Anti-Src Antibody (1E789)
<p>Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (3B845)
<p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
<p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>Forma y color:Odour LiquidA-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Fórmula:C34H39N9O3Pureza:99.23% - 99.86%Forma y color:SolidPeso molecular:621.73Anti-EGFR Antibody (7X976)
<p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (9S619)
Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
<p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>Forma y color:Odour LiquidPD 0325901
CAS:Fórmula:C16H14F3IN2O4Pureza:>97.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:482.20BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Forma y color:SolidPeso molecular:521.57PF-04217903 methanesulfonate
CAS:<p>PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).</p>Fórmula:C20H20N8O4SPureza:98%Forma y color:SolidPeso molecular:468.49DDR1-IN-4
CAS:<p>DDR1-IN-4 is a DDR1 inhibitor that inhibits autophosphorylation of DDR1 and DDR2 and can be used to study chronic kidney disease.</p>Fórmula:C23H20BrF3N6O3Pureza:97.25%Forma y color:SolidPeso molecular:565.34SU 1498
CAS:Fórmula:C25H30N2O2Pureza:>98.0%(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:390.53Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48SM27
CAS:<p>SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.</p>Fórmula:C21H16N2O9S2Pureza:98.83%Forma y color:SolidPeso molecular:504.49Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:557.05Nilotinib
CAS:Fórmula:C28H22F3N7OPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:529.53GDC-0834
CAS:<p>GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and</p>Fórmula:C33H36N6O3SForma y color:SolidPeso molecular:596.74Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19PP 2
CAS:Fórmula:C15H16ClN5Pureza:>97.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:301.78DT-3 acetate
<p>DT-3 acetate is a cell-permeable peptide that acts as an inhibitor of protein kinase G (PKGIα), effectively blocking the cGMP-PKG signaling pathway.</p>Fórmula:C152H258N52O28S·xC2H4O2Forma y color:SolidPeso molecular:3294.07 (free acid)Tyrphostin A9
CAS:Fórmula:C18H22N2OPureza:>98.0%(GC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:282.39
