GPCR / proteína G
Los inhibidores de GPCR/proteínas G son compuestos que se dirigen a los receptores acoplados a proteínas G (GPCR) y a las proteínas G asociadas, que desempeñan roles cruciales en la transmisión de señales desde el exterior hacia el interior de las células. Estos inhibidores son esenciales para estudiar las vías de señalización mediadas por los GPCR, que están involucradas en numerosos procesos fisiológicos, incluyendo la percepción sensorial, la respuesta inmunitaria y la neurotransmisión. Los inhibidores de GPCR también son importantes en el desarrollo de fármacos, ya que muchos agentes terapéuticos tienen como objetivo estos receptores. En CymitQuimica, ofrecemos una amplia gama de inhibidores de GPCR/proteínas G de alta calidad para apoyar su investigación en farmacología, biología celular y campos relacionados.
Subcategorías de "GPCR / proteína G"
- Receptor 5-HT(1.024 productos)
- Receptor de adenosina(249 productos)
- Receptor adrenérgico(3.030 productos)
- Receptor de bombesina(35 productos)
- Receptor de bradicinina(61 productos)
- CXCR(159 productos)
- CaSR(34 productos)
- Receptor de cannabinoides(217 productos)
- Colecistoquinina(1 productos)
- Receptor de dopamina(443 productos)
- Receptor de endotelina(86 productos)
- Receptor GNRH(84 productos)
- GPCR19(33 productos)
- GRK(33 productos)
- GTPasa(22 productos)
- Receptor de glucagón(196 productos)
- Hedgehog / Smoothened(49 productos)
- Receptor de histamina(385 productos)
- Receptor LPA(21 productos)
- Receptor de melatonina(26 productos)
- Receptor de OX(42 productos)
- Receptor de opioides(326 productos)
- PAFR(14 productos)
- PKA(54 productos)
- Receptor S1P(17 productos)
- SGLT(31 productos)
- Receptor sigma(46 productos)
Mostrar 19 subcategorías más
Se han encontrado 5981 productos de "GPCR / proteína G"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Ophiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Fórmula:C25H38O3Pureza:98%Forma y color:SolidPeso molecular:386.57SSTR5 antagonist 2 hydrochloride
SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.Fórmula:C32H36ClFN2O5Forma y color:SolidPeso molecular:583.09CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Forma y color:SolidAL 8810
CAS:AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].Fórmula:C24H31FO4Forma y color:SolidPeso molecular:402.5Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Fórmula:C20H26N4OForma y color:SolidPeso molecular:338.45LY 215840
CAS:5-HT2/5-HT7 receptor antagonistFórmula:C24H33N3O2Pureza:98%Forma y color:SolidPeso molecular:395.54Cicaprost
CAS:Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Fórmula:C22H30O5Forma y color:SolidPeso molecular:374.47Cendifensine
CAS:Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).Fórmula:C14H17Cl2NOForma y color:SolidPeso molecular:286.197H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511PD-147693
CAS:PD-147693 (compound II) is an active metabolite of the presynaptic dopamine autoreceptor agonist CI-1007, and it exhibits antipsychotic activity similar to CI-1007.Fórmula:C24H27NOPeso molecular:345.477FK-3657
CAS:FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.Fórmula:C30H27Cl2N5O4Forma y color:SolidPeso molecular:592.47Mafoprazine
CAS:Mafoprazine, a phenylpiperazine derivative, exhibits varying affinities for neuronal receptors, primarily exerting its antipsychotic effects through blocking D2 receptors and enhancing α-adrenergic activity. It also increases the activity of dopamine metabolites.Fórmula:C22H28FN3O3Forma y color:SolidPeso molecular:401.475-HT1A antagonist 1
Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.Fórmula:C23H29ClN6O2Forma y color:SolidPeso molecular:456.97MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.Fórmula:C24H23F3N6O3Forma y color:SolidPeso molecular:500.47MDA7
CAS:<p>MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.</p>Fórmula:C22H25NO2Forma y color:SolidPeso molecular:335.439Anthrotainin
CAS:Anthrotainin is a tetracyclic compound that acts as an inhibitor of the binding of P substance (substance P), with an IC50 of 3 μM.Fórmula:C20H17NO9Forma y color:SolidPeso molecular:415.35ZK118182 isopropyl ester
CAS:ZK118182 isopropyl ester is a PG analog with potent DP-agonist activity (EC50 = 16.5 nM) and high affinity for the DP receptor (Ki = 74 nM).Fórmula:C23H37ClO5Pureza:98%Forma y color:SolidPeso molecular:428.99AH22921
CAS:AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.Fórmula:C29H35NO5Forma y color:SolidPeso molecular:477.59M1069
M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.Fórmula:C25H30N4O8SForma y color:SolidPeso molecular:546.59Ro4368554
CAS:Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.Fórmula:C19H21N3O2SForma y color:SolidPeso molecular:355.454
