Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5599 produits trouvés pour "Apoptose"
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Apogossypolone
CAS :Produit contrôlé<p>Applications Apogossypolone is an anticancer agent that induces apoptosis in carcinoma cells. Antiproliferative.<br>References Zubair, H. et al.: Eur J. Pharm. Sci., 47, 280 (2012);<br></p>Formule :C28H26O8Couleur et forme :NeatMasse moléculaire :490.50N-Benzyloxycarbonyl-4-[(3R)-3-amino-1-oxo-4-(phenylthio)butyl]morpholine
CAS :<p>Applications Intermediate in the production of cell death regulators and apoptosis promoters.<br></p>Formule :C22H26N2O4SCouleur et forme :Off White OilyMasse moléculaire :414.52(R)-Irofulven
CAS :Produit contrôlé<p>Applications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic.<br>References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),<br></p>Formule :C15H18O3Couleur et forme :NeatMasse moléculaire :246.31Santamarine
CAS :<p>Applications Santamarine is a sesquiterpene lactone shows anticancer properties by inhibiting proliferation and inducing apoptosis.<br>References Mehmood, T., et al.: J. Cancer, 8, 1-11 (2017)<br></p>Formule :C15H20O3Couleur et forme :NeatMasse moléculaire :248.32L-Cystathionine
CAS :<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Formule :C7H14N2O4SDegré de pureté :96.43% - >99.99%Couleur et forme :SolidMasse moléculaire :222.26NPB
CAS :<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Formule :C29H31Cl2N3O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :524.48Cot inhibitor-2
CAS :<p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>Formule :C26H25Cl2FN8Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :539.43Flurochloridone
CAS :<p>Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.</p>Formule :C12H10Cl2F3NODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.12SAR405838
CAS :<p>MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.</p>Formule :C29H34Cl2FN3O3Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :562.5SU11274
CAS :<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Formule :C28H30ClN5O4SDegré de pureté :98.62% - 99.53%Couleur et forme :Orange PowderMasse moléculaire :568.09Riviciclib hydrochloride
CAS :<p>Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.</p>Formule :C21H20ClNO5·HClDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :438.3Camptothecin
CAS :<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Formule :C20H16N2O4Degré de pureté :99.52% - 99.88%Couleur et forme :Solid PowderMasse moléculaire :348.35Dibenz[a,h]anthracene
CAS :<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Formule :C22H14Degré de pureté :99.97%Couleur et forme :Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Masse moléculaire :278.35Mutant p53 modulator-1
CAS :<p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>Formule :C27H32F4N8O2Couleur et forme :SolidMasse moléculaire :576.59Atopaxar
CAS :<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formule :C29H38FN3O5Degré de pureté :97.07% - 98.07%Couleur et forme :SolidMasse moléculaire :527.63PERK-IN-3
CAS :<p>PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).</p>Formule :C22H16F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.38Anticancer agent 164
CAS :<p>CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid</p>Formule :C21H23F3N8O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.58Dimethoate
CAS :<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Formule :C5H12NO3PS2Degré de pureté :99.74% - 99.91%Couleur et forme :White Crystalline SolidMasse moléculaire :229.26Ac-IETD-CHO
CAS :<p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>Formule :C21H34N4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.52Antitumor agent-115
CAS :<p>Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.</p>Formule :C19H38ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.96Methylisothiazolinone
CAS :<p>Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.</p>Formule :C4H5NOSDegré de pureté :99.78%Couleur et forme :Colorless Prisms LiquidMasse moléculaire :115.15Tubulin polymerization-IN-17
CAS :<p>Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.</p>Formule :C26H23NO5Couleur et forme :SolidMasse moléculaire :429.46CMLD012073
CAS :<p>CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.</p>Formule :C30H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :530.57CAM 833
CAS :<p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>Formule :C26H26ClFN4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :528.96Nec-3a
CAS :<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formule :C21H18F4N2O4Couleur et forme :SolidMasse moléculaire :438.37Ludartin
CAS :<p>Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.</p>Formule :C15H18O3Couleur et forme :SolidMasse moléculaire :246.3HBV-IN-23
CAS :<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formule :C25H27N3O3SCouleur et forme :SolidMasse moléculaire :449.57(S)-PERK-IN-5
CAS :<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5CHMFL-ABL/KIT-155
CAS :<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Formule :C33H38F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :609.68(rel)-Oxaliplatin
CAS :<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Formule :C8H14N2O4PtCouleur et forme :SolidMasse moléculaire :397.29ATX inhibitor 13
CAS :<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Formule :C31H35Cl2N5O3Couleur et forme :SolidMasse moléculaire :596.55Topoisomerase II inhibitor 7
CAS :<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Formule :C32H28BrN5O5SCouleur et forme :SolidMasse moléculaire :674.56QTX125
CAS :<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Formule :C23H19N3O5Couleur et forme :SolidMasse moléculaire :417.41TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Formule :C20H21N5OSCouleur et forme :SolidMasse moléculaire :379.48Vin-F03
CAS :<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49RET-IN-16
CAS :<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Formule :C31H29F3N8O2Couleur et forme :SolidMasse moléculaire :602.61PD-1/PD-L1-IN-29
CAS :<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Formule :C26H24N2O6Couleur et forme :SolidMasse moléculaire :460.48MPT0B214
CAS :<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Formule :C20H20N2O5Couleur et forme :SolidMasse moléculaire :368.38Se-Methylselenocysteine hydrochloride
CAS :<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Formule :C4H10ClNO2SeDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :218.54Bcl-2/Mcl-1-IN-2
CAS :<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Formule :C26H24ClNO3Couleur et forme :SolidMasse moléculaire :433.93Mcl1-IN-3
CAS :<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93SEC
CAS :<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Formule :C22H23ClN2O5Couleur et forme :SolidMasse moléculaire :430.88GLS1 Inhibitor-4
CAS :<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72FD223
CAS :<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Formule :C17H12ClN5O2SCouleur et forme :SolidMasse moléculaire :385.83PDPOB
CAS :<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32AV123
CAS :<p>AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.</p>Formule :C11H14N4O2Couleur et forme :SolidMasse moléculaire :234.25pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71CAY10773
CAS :<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Formule :C22H17Cl2N5OCouleur et forme :SolidMasse moléculaire :438.31Quinidine polygalacturonate
CAS :<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formule :C26H34N2O9Couleur et forme :SolidMasse moléculaire :518.22643GL-V9
CAS :<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Formule :C27H24N4O2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :436.51MX107
CAS :<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49EGFR-IN-60
CAS :<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Formule :C28H28Cl2N6OCouleur et forme :SolidMasse moléculaire :535.47PC-046
CAS :<p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39Tubulin inhibitor 23
CAS :<p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>Formule :C26H23NO6SCouleur et forme :SolidMasse moléculaire :477.53CAY10682
CAS :<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Formule :C30H25BrFN5OCouleur et forme :SolidMasse moléculaire :570.45n-Octyl caffeate
CAS :<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37DMH2
CAS :<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Formule :C27H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.52NSC 107512
CAS :<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Formule :C12H16N6O5Couleur et forme :SolidMasse moléculaire :324.29IZTZ-1
CAS :<p>IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.</p>Formule :C32H35N7SCouleur et forme :SolidMasse moléculaire :549.73PD-1/PD-L1-IN 6
CAS :<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49Lexibulin dihydrochloride
CAS :<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Formule :C24H32Cl2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.46Tubulin inhibitor 30
CAS :<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4CRA-026440
CAS :<p>CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7</p>Formule :C23H24N4O4Degré de pureté :96.42%Couleur et forme :SolidMasse moléculaire :420.46A-385358
CAS :<p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>Formule :C32H41N5O5S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :639.83CN128 hydrochloride
CAS :<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formule :C15H18ClNO3Couleur et forme :SolidMasse moléculaire :295.76IMM-H004
CAS :<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Formule :C16H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.34S116836
CAS :<p>S116836 is a tyrosine kinase inhibitor.</p>Formule :C27H21F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.49BTK-IN-24
CAS :<p>BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.</p>Formule :C26H19F4N5O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :509.46ICG-001
CAS :<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formule :C33H32N4O4Degré de pureté :99.55% - 99.62%Couleur et forme :SolidMasse moléculaire :548.63Antitumor agent-53
CAS :<p>Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.</p>Formule :C24H18FN3OCouleur et forme :SolidMasse moléculaire :383.42PTG-0861
CAS :<p>PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.</p>Formule :C15H9F5N2O3Couleur et forme :SolidMasse moléculaire :360.24NMK-TD-100
CAS :<p>NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.</p>Formule :C19H17N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.42DPQZ
CAS :<p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>Formule :C20H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.37PD1-PDL1-IN 1
CAS :<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Formule :C14H23N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.38SKLB70326
CAS :<p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>Formule :C15H13N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.35CAY10747
CAS :<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Formule :C42H48FNO6Couleur et forme :SolidMasse moléculaire :681.83Mcl1-IN-4
CAS :Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58Antitumor agent-70
CAS :<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39USP7-IN-4
CAS :<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Formule :C29H34N6O3Degré de pureté :98.27% - 99.09%Couleur et forme :SolidMasse moléculaire :514.62PARP-2-IN-3
CAS :<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Formule :C20H20ClN3O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :385.84CPI-7c
CAS :<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Formule :C22H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.39DPBQ
CAS :<p>DPBQ (ZINC1620467) is a p53 activator.</p>Formule :C24H14N2O2Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :362.38Anticancer agent 57
CAS :<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Formule :C20H21Cl2NO2Couleur et forme :SolidMasse moléculaire :378.29Filanesib
CAS :<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Formule :C20H22F2N4O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.48BCL6-IN-8c
CAS :<p>BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent</p>Formule :C20H20ClN3O5Couleur et forme :SolidMasse moléculaire :417.84Ivaltinostat
CAS :<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54TP-472
CAS :<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Formule :C20H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38GW7845
CAS :<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Formule :C29H28N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.54Anticancer agent 77
CAS :<p>Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.</p>Formule :C25H30BrN7Couleur et forme :SolidMasse moléculaire :508.46DNL343
CAS :<p>DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.</p>Formule :C20H19ClF3N3O4Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :457.83AG-024322
CAS :<p>AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.</p>Formule :C23H20F2N6Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :418.44hCAIX-IN-12
CAS :<p>hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.</p>Formule :C18H14N4O3S2Couleur et forme :SolidMasse moléculaire :398.46Antitumor agent-45
CAS :<p>Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.</p>Formule :C28H17BrFN5O3Couleur et forme :SolidMasse moléculaire :570.37A 410099.1
CAS :<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1RC-33 HCl
CAS :<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Formule :C21H28ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.91SK-7041
CAS :<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formule :C19H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.39Verticillin A
CAS :<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formule :C30H28N6O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.84VMY-1-103
CAS :<p>VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.</p>Formule :C34H42ClN9O4SCouleur et forme :SolidMasse moléculaire :708.27Bcl-2/Mcl-1-IN-1
CAS :<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Formule :C28H23NO3Couleur et forme :SolidMasse moléculaire :421.49
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