Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(135 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6225 produits trouvés pour "Apoptose"
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D-Saccharic acid 1,4-lactone hydrate
CAS :D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.Formule :C17H20ClN3ODegré de pureté :99.49% - ≥98%Couleur et forme :SolidMasse moléculaire :317.81Elevenostat
CAS :Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.Formule :C16H17N3O4Degré de pureté :95% - 96.14%Couleur et forme :SolidMasse moléculaire :315.32Tilmicosin phosphate
CAS :Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.Formule :C46H83N2O17PDegré de pureté :95.29% - 97.13%Couleur et forme :Light Yellow PowderMasse moléculaire :967.1Fluazinam
CAS :Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.Formule :C13H4Cl2F6N4O4Degré de pureté :98% - 99.98%Couleur et forme :Light Yellow CrystalsMasse moléculaire :465.09PKCβ inhibitor 1
CAS :PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,Formule :C24H21N5O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :411.46Ref: TM-T8376
500µg37,00€1mg52,00€5mg101,00€1mL*10mM (DMSO)110,00€10mg177,00€25mg391,00€50mg692,00€100mg945,00€L-Ascorbic acid sodium salt
CAS :L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.Formule :C6H7NaO6Degré de pureté :98.73% - 99.75%Couleur et forme :Less Solid PowderMasse moléculaire :198.11LY-294002 hydrochloride
CAS :LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.Formule :C19H17NO3·HClDegré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :343.81Amcasertib
CAS :Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.
Formule :C31H33N5O2SDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :539.692'-OMe-Guanosine
CAS :2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Formule :C11H15N5O5Degré de pureté :99.93%Couleur et forme :White SolidMasse moléculaire :297.27Linderalactone
CAS :1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T5S1897
1mg43,00€5mg84,00€1mL*10mM (DMSO)102,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€1R,3S-RSL 3
CAS :1R,3S-RSL 3 is a harmala alkaloid.Formule :C23H21ClN2O5Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :440.88Ref: TM-T9561
1mg86,00€5mg177,00€1mL*10mM (DMSO)207,00€10mg265,00€25mg427,00€50mg605,00€100mg800,00€200mg1.071,00€TVB-3166
CAS :TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).Formule :C24H24N4ODegré de pureté :99.53% - 99.57%Couleur et forme :SolidMasse moléculaire :384.47Ref: TM-T17180
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg195,00€50mg334,00€100mg500,00€Sirtinol
CAS :Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6671
2mg40,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg88,00€25mg170,00€50mg324,00€100mg482,00€500mg1.063,00€Calycosin
CAS :Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).
Formule :C16H12O5Degré de pureté :99.91% - >99.99%Couleur et forme :White PowderMasse moléculaire :284.26FIN56
CAS :FIN56 is a specific inducer of ferroptosis.Formule :C25H31N3O5S2Degré de pureté :99.72% - 99.78%Couleur et forme :SolidMasse moléculaire :517.66Ref: TM-T4066
2mg42,00€5mg63,00€1mL*10mM (DMSO)72,00€10mg89,00€25mg192,00€50mg341,00€100mg535,00€200mg748,00€Volasertib
CAS :Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.Formule :C34H50N8O3Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :618.81Ref: TM-T6019
1mg37,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)96,00€10mg114,00€25mg205,00€50mg334,00€100mg557,00€Triptolide
CAS :Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formule :C20H24O6Degré de pureté :97.19% - 99.97%Couleur et forme :White To Off-White SolidMasse moléculaire :360.40Ref: TM-T2179
1mg39,00€2mg52,00€1mL*10mM (DMSO)75,00€5mg95,00€10mg123,00€25mg225,00€50mg315,00€100mg444,00€Quisinostat
CAS :Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47α-Hederin
CAS :Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.Formule :C41H66O12Degré de pureté :99.44% - 99.89%Couleur et forme :SolidMasse moléculaire :750.96Ref: TM-T3368
1mg34,00€5mg65,00€1mL*10mM (DMSO)84,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€200mg423,00€BMS-536924
CAS :BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96Genistein
CAS :Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24(1E,6E)-Bis(demethoxy)curcumin
CAS :(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formule :C19H16O4Degré de pureté :97.45% - 98.39%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T6S1688
5mg42,00€1mL*10mM (DMSO)49,00€10mg52,00€25mg81,00€50mg105,00€100mg152,00€500mg353,00€AZ 628
CAS :AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formule :C27H25N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :451.52Tasisulam
CAS :Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.Formule :C11H6BrCl2NO3S2Degré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :415.11Ref: TM-T6191
5mg39,00€1mL*10mM (DMSO)56,00€10mg58,00€25mg117,00€50mg193,00€100mg289,00€200mg434,00€500mg710,00€Iproniazid
CAS :Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.Formule :C9H13N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22Wedelolactone
CAS :Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formule :C16H10O7Degré de pureté :98.07% - 99.87%Couleur et forme :SolidMasse moléculaire :314.25Ref: TM-T3384
1mg34,00€1mL*10mM (DMSO)50,00€5mg71,00€10mg109,00€25mg175,00€50mg314,00€100mg414,00€500mg954,00€Pevonedistat
CAS :Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).Formule :C21H25N5O4SDegré de pureté :95% - 99.92%Couleur et forme :SolidMasse moléculaire :443.52Ref: TM-T6332
1mg50,00€2mg66,00€1mL*10mM (DMSO)88,00€5mg90,00€10mg137,00€25mg245,00€50mg401,00€100mg680,00€PKR-IN-C16
CAS :PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.Formule :C13H8N4OSDegré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :268.29Ref: TM-T16550
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)105,00€10mg130,00€25mg260,00€50mg409,00€100mg605,00€Neferine
CAS :Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formule :C38H44N2O6Degré de pureté :98.81% - 99.65%Couleur et forme :SolidMasse moléculaire :624.77Momordin Ic
CAS :Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunctionFormule :C41H64O13Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :764.94Infigratinib
CAS :Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 andFormule :C26H31Cl2N7O3Degré de pureté :98% - 98.97%Couleur et forme :SolidMasse moléculaire :560.48Ref: TM-T1975
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€25mg84,00€50mg90,00€100mg144,00€200mg259,00€500mg437,00€Z-VAD(OMe)-FMK
CAS :View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.Formule :C22H30FN3O7Degré de pureté :95.92% - 99.71%Couleur et forme :SolidMasse moléculaire :467.49Ref: TM-T6013
1mg54,00€2mg84,00€5mg137,00€1mL*10mM (DMSO)138,00€10mg222,00€25mg331,00€50mg447,00€100mg623,00€200mg883,00€Bacopaside II
CAS :Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.Formule :C47H76O18Degré de pureté :98.14% - 99.86%Couleur et forme :SolidMasse moléculaire :929.10Evocarpine
CAS :Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
Formule :C23H33NODegré de pureté :99.77% - 99.819%Couleur et forme :SolidMasse moléculaire :339.51CDPPB
CAS :CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
Formule :C23H16N4ODegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :364.4SJ-172550
CAS :SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).Formule :C22H21ClN2O5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :428.87Ref: TM-T16888
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg175,00€50mg334,00€100mg575,00€500mg1.198,00€α-Thujone
CAS :α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23CP-724714
CAS :CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2Formule :C27H27N5O3Degré de pureté :97.1% - 98.82%Couleur et forme :SolidMasse moléculaire :469.54Ref: TM-T4014
1mg42,00€2mg55,00€5mg90,00€1mL*10mM (DMSO)94,00€10mg148,00€25mg259,00€50mg429,00€100mg625,00€Phenazine methylsulfate
CAS :Phenazine methylsulfate is anti-bacterial agents.Formule :C14H14N2O4SDegré de pureté :97.67% - >99.99%Couleur et forme :Yellow CrystallineMasse moléculaire :306.34ASP3026
CAS :ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formule :C29H40N8O3SDegré de pureté :98.78% - 99.81%Couleur et forme :SolidMasse moléculaire :580.74Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.67%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg47,00€1mL*10mM (DMSO)52,00€10mg69,00€25mg123,00€50mg177,00€100mg304,00€200mg447,00€500mg713,00€CCT 137690
CAS :CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48Capmatinib 2HCl
CAS :Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.Formule :C23H19Cl2FN6ODegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :485.34Ref: TM-T4260
2mg34,00€5mg49,00€1mL*10mM (DMSO)58,00€10mg64,00€25mg84,00€50mg92,00€100mg126,00€500mg303,00€1A-116
CAS :1A-116 is a specific Rac1 inhibitor.Formule :C16H16F3N3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :307.31Ref: TM-T14004
1mg52,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg158,00€25mg268,00€50mg421,00€100mg620,00€200mg875,00€KY-05009
CAS :KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).Formule :C18H16N4O2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :352.41Ref: TM-T11793
5mg48,00€1mL*10mM (DMSO)49,00€10mg67,00€25mg111,00€50mg161,00€100mg231,00€200mg335,00€BTZO-1
CAS :BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.Formule :C13H8N2OSDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :240.28Ref: TM-T7845
2mg34,00€5mg50,00€1mL*10mM (DMSO)56,00€10mg85,00€25mg154,00€50mg222,00€100mg331,00€200mg470,00€COTI-2
CAS :COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.Formule :C19H22N6SDegré de pureté :99% - 99.55%Couleur et forme :SolidMasse moléculaire :366.48Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Formule :C43H68N12O14SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :1009.14CI-1040
CAS :CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).Formule :C17H14ClF2IN2O2Degré de pureté :99.64%Couleur et forme :Off-White To Pale Beige SolidMasse moléculaire :478.66Salidroside
CAS :Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formule :C14H20O7Degré de pureté :97.81%Couleur et forme :Red-Brown Fine PowderMasse moléculaire :300.30Ref: TM-T2717
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg130,00€50mg178,00€100mg268,00€200mg408,00€C-DIM12
CAS :C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.Formule :C23H17ClN2Degré de pureté :97.72% - ≥95%Couleur et forme :SolidMasse moléculaire :356.85TREM2-IN-1
CAS :TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophagesFormule :C46H68N2O20PtDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :1164.12NUN82647
CAS :NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.Formule :C15H13N3O2SDegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :299.35Ref: TM-T8331
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg133,00€25mg236,00€50mg356,00€100mg522,00€200mg705,00€Enzastaurin
CAS :Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formule :C32H29N5O2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :515.6CA-5f
CAS :CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46McMMAF
CAS :McMMAF is a protective group-conjugated MMAF.Formule :C49H76N6O11Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :925.16WYE-354
CAS :WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53SEC inhibitor KL-1
CAS :KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.Formule :C18H16ClNO4Degré de pureté :97.42%Couleur et forme :SolidMasse moléculaire :345.78Ref: TM-T16867
1mg38,00€2mg52,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg124,00€25mg205,00€50mg309,00€100mg439,00€200mg610,00€Tomatine
CAS :Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formule :C50H83NO21Degré de pureté :98.42% - 99.94%Couleur et forme :White To Light YellowMasse moléculaire :1034.19MG-101
CAS :MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formule :C20H37N3O4Degré de pureté :98% - ≥98%Couleur et forme :SolidMasse moléculaire :383.53A-1331852
CAS :Produit contrôléApplications A-1331852 is a substituted benzothiazole that can serve as an anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.
References Wang, L., et al.: PCT Int. Appl. WO 2013055897 A1 20130418. Apr 18, 2013Formule :C38H38N6O3SCouleur et forme :NeatMasse moléculaire :658.81Neoponcirin (Mixture of diastereomers)
CAS :Produit contrôléFormule :C28H34O14Couleur et forme :NeatMasse moléculaire :594.56Vamifeport
CAS :Vamifeport (VIT-2763), an inhibitor targeting iron transport proteins, improves anemia and erythropoiesis and can be studied β-thalassemiaFormule :C21H21FN6O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :408.43N1-Acetylspermidine hydrochloride
CAS :N1-Acetylspermidine HCl, an acetyl spermidine derivative, boosts polyamine oxidase levels in colorectal adenocarcinomas.Formule :C9H23Cl2N3ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :260.2L-Glutamic acid monosodium salt monohydrate
CAS :L-Glutamic acid monosodium salt monohydrate (MSG monohydrate) is an important food additive with gastrointestinal protective effects.Formule :C5H10NNaO5Degré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :187.13BC-1471
CAS :BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.Formule :C27H32N4O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :508.63Ref: TM-T8553
1mg58,00€5mg128,00€1mL*10mM (DMSO)144,00€10mg187,00€25mg323,00€50mg482,00€100mg658,00€200mg888,00€Etaracizumab
CAS :Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.Degré de pureté :96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.64 kDaCSRM617 hydrochloride
CAS :CSRM617 hydrochloride: selective OC2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer.Formule :C10H14ClN3O5Degré de pureté :99.59%Couleur et forme :SoildMasse moléculaire :291.69Embelin
CAS :Produit contrôléApplications Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embelin also displays contraceptive and pro-apoptotic properties.
References Stasiuk, M. et al.: Glob. J. Biochem., 2, 262 (2011); Brahmeshwari, G. et al.: Adv. Plant Sci., 24, 467 (2011); Hu, R. et al.: Med. Oncol., 28, 1598 (2011);Formule :C17H26O4Couleur et forme :OrangeMasse moléculaire :294.39GSK1904529A
CAS :GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Formule :C44H47F2N9O5SDegré de pureté :98.2% - 99.76%Couleur et forme :SolidMasse moléculaire :851.96Meloxicam
CAS :Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formule :C14H13N3O4S2Degré de pureté :97.09% - 99.60%Couleur et forme :Light Yellow SolidMasse moléculaire :351.40RAPTA-C
CAS :RAPTA-C 可通过线粒体和 p53-JNK 途径诱导 EAC 细胞周期停滞和凋亡，可用于研究乳腺癌和卵巢癌。Formule :C16H26Cl2N3PRuDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :463.35Tamsulosin
CAS :Tamsulosin: an alpha1A blocker for easing urination in BPH by relaxing prostate and bladder muscles.Formule :C20H28N2O5SDegré de pureté :99.93%Couleur et forme :White CrystalsMasse moléculaire :408.51Tributyrin
CAS :Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid.Formule :C15H26O6Degré de pureté :96.35% - 97.01%Couleur et forme :Colorless LiquidMasse moléculaire :302.36(S)-(+)-Ibuprofen
CAS :(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Formule :C13H18O2Degré de pureté :99.51% - 99.86%Couleur et forme :Colourless Crystalline SolidMasse moléculaire :206.28Pyropheophorbide A Methyl Ester
CAS :Produit contrôléStability Light Sensitive
Applications Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth.
References Bensasson, R., et al.: Nature, 290, 329 (1981); Moore, A., et al.: Science, 216, 982 (1982)Formule :C34H36N4O3Couleur et forme :NeatMasse moléculaire :548.67Bisindolylmaleimide VIII Acetic Acid Salt
CAS :Produit contrôléApplications It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism.
References Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000),Formule :C26H26N4O4Couleur et forme :NeatMasse moléculaire :458.51(S)-JQ-35
CAS :(S)-JQ-35 (TEN-010) is a BET bromodomain inhibitor with anti-tumor activity, particularly in breast cancer research.Formule :C27H34ClN7OSDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :540.12Socazolimab
CAS :Socazolimab (ZKAB001) is a monoclonal antibody targeting PD-L1 with antitumor activity, used in studies of recurrent or metastatic cervical cancer.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :143.06 kDaSeribantumab
CAS :Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting cancer cell proliferation.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :143.14 kDaFINO2
CAS :FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formule :C15H28O3Degré de pureté :97.27%Couleur et forme :SoildMasse moléculaire :256.38ARB-272572
CAS :ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.67Ref: TM-T39914
1mg123,00€5mg295,00€1mL*10mM (DMSO)353,00€10mg425,00€25mg712,00€50mg1.035,00€100mg1.485,00€200mg1.998,00€Meclizine
CAS :Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptorsFormule :C25H27ClN2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :390.95Cholesteryl Hemisuccinate
CAS :Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective,Formule :C31H50O4Degré de pureté :97.09% - 99.98%Couleur et forme :White PowderMasse moléculaire :486.732′,2′-Difluorodeoxyuridine
CAS :2′,2′-Difluorodeoxyuridine has anticancer activity, and shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.Formule :C9H10F2N2O5Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :264.18AOH1996
CAS :AOH1996: Oral PCNA ligand, disrupts TRC, triggers DNA stress, apoptosis, and enhances DNA damage agent effects.Formule :C26H22N2O4Degré de pureté :98.63% - 99.62%Couleur et forme :SoildMasse moléculaire :426.46Envafolimab
CAS :Envafolimab (ASC 22) is a humanized antibody targeting PD-L1, with anticancer activity, blocking the PD-L1 and PD-1 interaction.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :80 kDaEasyStep Human GDF15(Growth Differentiation Factor 15) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GDF15, and the Human GDF15 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human GDF15. After TMB substrate solution is added, only those wells that contain Human GDF15 and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human GDF15 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidPOMHEX
CAS :Pomhex, a cell-penetrating ENO2 inhibitor, thwarts glycolysis to combat ENO1-deficient tumors.Formule :C17H30NO9PDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :423.4N6-(2-Hydroxyethyl)adenosine
CAS :N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.Formule :C12H17N5O5Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :311.29Purpurin 18
CAS :Purpurin 18 is an interesting dihydroporphyrin for generating photosensitizers. It has antioxidant activityFormule :C33H32N4O5Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :564.63SSK1
CAS :SSK1 is a senescent cell-killing and β-galactosidase-targeting precursor compound that activates phosphorylation levels of p38 MAPK in senescent cells.Formule :C31H34F2N4O18Degré de pureté :98.88% - 99.48%Couleur et forme :SolidMasse moléculaire :788.61Ref: TM-T37450
1mg145,00€5mg334,00€1mL*10mM (DMSO)439,00€10mg505,00€25mg803,00€50mg1.108,00€100mg1.558,00€200mg2.097,00€Eurycomanone
CAS :Produit contrôléApplications Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
References Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);Formule :C20H24O9·2H2ODegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :444.43Adebrelimab
CAS :Adebrelimab (SHR-1316) is a humanized monoclonal antibody targeting PD-L1 with antitumor activity for the study of solid tumors.Degré de pureté :97.8% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.54 kDaKW-2450 free base
CAS :KW-2450 free base is a multiple inhibitor of IGF-1R/IR and tyrosine kinases with antitumor activity.Formule :C28H29N5O3SDegré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :515.63Tirabrutinib
CAS :Tirabrutinib, an oral Btk inhibitor (IC50=6.8 nM), crosses the BBB and halts B cell signaling for autoimmune and hematologic studies.Formule :C25H22N6O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :454.48CCT241161
CAS :CCT241161: oral pan-RAF inhibitor; IC50s: LCK (3 nM), CRAF (6), SRC (10), V600E-BRAF (15), BRAF (30); fights BRAF/NRAS melanomas, anti-proliferative.Formule :C28H27N7O3SDegré de pureté :99.76% - 99.77%Couleur et forme :SolidMasse moléculaire :541.62EasyStep Human VEGFA(Vascular Endothelial Growth Factor A) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human VEGFA, and the Human VEGFA standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human VEGFA. After TMB substrate solution is added, only those wells that contain Human VEGFA and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human VEGFA in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless Transparentliquid(-)-β-Bisabolene (>85%)
CAS :Produit contrôléApplications Bisabolene is a sesquiterpene and can be extracted from oregano and other aromatic plants. It may be a potential anticancer agent that can induce apoptosis in A549 cancer cell line.
References Grosso, N. R., et al.: Argent., Pat. Appl. AR 90961 A1 20141217 (2014); Yfanti, P., et al.: Am J Plant Sci. 6, 2092 (2015)Formule :C15H24Degré de pureté :>85%Couleur et forme :Colourless To Light YellowMasse moléculaire :204.35Santalol
CAS :α-Santalol: antibacterial, antioxidant, anti-tumor, antimitotic, and antifungal against Trichophyton rubrum.Formule :C15H24ODegré de pureté :94.41%Couleur et forme :SolidMasse moléculaire :220.35
