Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(135 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6225 produits trouvés pour "Apoptose"
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Thalidomide 5-fluoride
CAS :Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 proteinFormule :C13H9FN2O4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :276.22C-DIM12
CAS :C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.Formule :C23H17ClN2Degré de pureté :97.72% - ≥95%Couleur et forme :SolidMasse moléculaire :356.85Glutathione sodium
CAS :Glutathione sodium, a water-soluble form of PAO, blocks blood vessel formation and cancer growth.Formule :C10H16N3NaO6SCouleur et forme :SolidMasse moléculaire :329.3dl-Maackiain
CAS :1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.Formule :C16H12O5Degré de pureté :97.36% - 99.89%Couleur et forme :SolidMasse moléculaire :284.26Lanperisone
CAS :Lanperisone is a muscle relaxant.Formule :C15H18F3NOCouleur et forme :SolidMasse moléculaire :285.3GDC-0623
CAS :GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.Formule :C16H14FIN4O3Degré de pureté :98.95% - 99.02%Couleur et forme :SolidMasse moléculaire :456.21Ref: TM-T6843
1mg50,00€2mg70,00€5mg113,00€1mL*10mM (DMSO)113,00€10mg177,00€25mg265,00€50mg349,00€100mg580,00€PFK-158
CAS :PFK-158 is an effective and specific inhibitor PFKFB3.Formule :C18H11F3N2ODegré de pureté :95.49% - 99.16%Couleur et forme :SolidMasse moléculaire :328.29Ref: TM-T3105
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg170,00€50mg259,00€100mg409,00€SP-420
CAS :SP-420 is a novel orally active iron chelator.Formule :C16H21NO6SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :355.41Necroptosis-IN-1
CAS :Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.Formule :C12H10ClN3O2Degré de pureté :99.73% - 99.8%Couleur et forme :SolidMasse moléculaire :263.68Ref: TM-T9305
1mg60,00€5mg111,00€1mL*10mM (DMSO)141,00€10mg177,00€25mg301,00€50mg425,00€100mg605,00€200mg797,00€HS-1793
CAS :HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.Formule :C16H12O3Degré de pureté :98.16% - 99.82%Couleur et forme :SolidMasse moléculaire :252.26L-685458
CAS :L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.Formule :C39H52N4O6Degré de pureté :99.62% - 99.80%Couleur et forme :SolidMasse moléculaire :672.85Ref: TM-T6870
1mg113,00€5mg334,00€1mL*10mM (DMSO)497,00€10mg520,00€25mg840,00€50mg1.144,00€100mg1.521,00€Momelotinib
CAS :Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formule :C23H22N6O2Degré de pureté :97.07% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T1849
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg89,00€25mg158,00€50mg245,00€100mg385,00€200mg592,00€Kahweol
CAS :Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42Madecassoside
CAS :Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormule :C48H78O20Degré de pureté :99.46% - 99.85%Couleur et forme :White PowderMasse moléculaire :975.12Ref: TM-T2813
10mg49,00€1mL*10mM (DMSO)49,00€25mg84,00€50mg120,00€100mg178,00€200mg289,00€500mg485,00€PAC-1
CAS :PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formule :C23H28N4O2Degré de pureté :96.78% - 99.76%Couleur et forme :SolidMasse moléculaire :392.49RA-9
CAS :RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.Formule :C19H15N3O5Degré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :365.34Pantoprazole sodium
CAS :Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35B-AP15
CAS :B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.Formule :C22H17N3O6Degré de pureté :91.43% - 98.77%Couleur et forme :SolidMasse moléculaire :419.39Citronellyl acetate
CAS :Citronellyl acetate is a natural productFormule :C12H22O2Degré de pureté :98%Couleur et forme :LiquidMasse moléculaire :198.30Picropodophyllin
CAS :Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.Formule :C22H22O8Degré de pureté :98.38% - 99.83%Couleur et forme :SolidMasse moléculaire :414.41Ref: TM-T6943
5mg64,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg170,00€50mg316,00€100mg535,00€500mg1.121,00€PR-619
CAS :PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Formule :C7H5N5S2Degré de pureté :97.25% - >99.99%Couleur et forme :SolidMasse moléculaire :223.284-Nitroquinoline 1-oxide
CAS :4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts ofFormule :C9H6N2O3Degré de pureté :97.4% - 99.94%Couleur et forme :Yellow Needles Or Plates From Acetone Physical Description Yellowish-Brown Plates Or Needles Or Yellow Solid (Ntp 1992)Masse moléculaire :190.16(R)-(-)-Gossypol acetic acid
CAS :(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.Formule :C30H30O8·C2H4O2Degré de pureté :98.88% - 99.5%Couleur et forme :SolidMasse moléculaire :578.61CBL0137
CAS :CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM).Formule :C21H24N2O2Degré de pureté :99.57% - 99.68%Couleur et forme :SolidMasse moléculaire :336.43Etalocib
CAS :Etalocib (LY293111) is a potent diaryl ether inhibitor blocking LTB4 receptor and 5'-lipoxygenase, with antineoplastic properties.Formule :C33H33FO6Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :544.6Ref: TM-T22358
1mg67,00€5mg152,00€1mL*10mM (DMSO)182,00€10mg215,00€25mg398,00€50mg583,00€100mg837,00€200mg1.125,00€Tiplaxtinin
CAS :Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.1% - 99.93%Couleur et forme :SolidMasse moléculaire :558.70Ginkgolide B
CAS :Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.Formule :C20H24O10Degré de pureté :98.66% - 99.81%Couleur et forme :White Crystal PowderMasse moléculaire :424.40Roquinimex
CAS :Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormule :C18H16N2O3Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :308.33Toyocamycin
CAS :Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (Formule :C12H13N5O4Degré de pureté :98.1% - 99.44%Couleur et forme :SolidMasse moléculaire :291.26Ref: TM-T17143
5mg44,00€1mL*10mM (DMSO)48,00€10mg62,00€25mg107,00€50mg192,00€100mg334,00€500mg782,00€trans-Chalcone
CAS :trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively asFormule :C15H12ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :208.26Icaritin
CAS :Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formule :C21H20O6Degré de pureté :97.69% - 99.76%Couleur et forme :SolidMasse moléculaire :368.38Avitinib
CAS :Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.53EPZ004777
CAS :EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formule :C28H41N7O4Degré de pureté :98.99% - 99.32%Couleur et forme :SolidMasse moléculaire :539.67Divalproex Sodium
CAS :Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormule :C8H16O2·C8H15O2·NaDegré de pureté :99.87%Couleur et forme :A White Powder With A Characteristic OdorMasse moléculaire :310.41Ref: TM-T6474
10mg37,00€25mg52,00€1mL*10mM (DMSO)52,00€50mg74,00€100mg110,00€200mg178,00€500mg318,00€Angiotensin II human acetate
CAS :Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.Formule :C52H75N13O14Degré de pureté :98.89% - 99.78%Couleur et forme :SolidMasse moléculaire :1106.2BIBR 1532
CAS :BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
Formule :C21H17NO3Degré de pureté :98.49% - 98.90%Couleur et forme :SolidMasse moléculaire :331.36(Rac)-Benpyrine
CAS :(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formule :C16H16N6ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€Nirogacestat
CAS :Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).Formule :C27H41F2N5ODegré de pureté :97.98% - 99.63%Couleur et forme :SolidMasse moléculaire :489.64Ref: TM-T6935
1mg35,00€5mg78,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg236,00€50mg447,00€100mg675,00€200mg888,00€Tyrphostin AG 879
CAS :Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Formule :C18H24N2OSDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :316.46AGK2
CAS :AGK2（IC50=3.5 μM） is an effective, and specific SIRT2 inhibitor.
Formule :C23H13Cl2N3O2Degré de pureté :98.68% - 99.17%Couleur et forme :SolidMasse moléculaire :434.27Rapanone
CAS :Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.Formule :C19H30O4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :322.44HS-173
CAS :HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).Formule :C21H18N4O4SDegré de pureté :99.33% - 99.64%Couleur et forme :SolidMasse moléculaire :422.46Ref: TM-T2308
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg77,00€25mg128,00€50mg200,00€100mg296,00€200mg425,00€RHPS4
CAS :RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
Formule :C22H17F2N2·CH3O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :458.48Bafilomycin A1
CAS :Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83HYPOCRELLIN B
CAS :HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.Formule :C30H24O9Degré de pureté :98% - 98.87%Couleur et forme :SolidMasse moléculaire :528.51SHR0302
CAS :SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formule :C18H22N8O2SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :414.48Ref: TM-T9195
1mg75,00€1mL*10mM (DMSO)164,00€5mg173,00€10mg281,00€25mg485,00€50mg773,00€100mg1.243,00€Malachite green oxalate
CAS :Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formule :C23H25N2·C2HO4C2H2O4Couleur et forme :Dark Green Crystals With A Metallic LusterMasse moléculaire :463.51Cabozantinib hydrochloride
CAS :Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€S55746 hydrochloride
CAS :S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.Formule :C43H43ClN4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :747.284-Methylbenzylidene camphor
CAS :4-Methylbenzylidene camphor: UVB blocker in sunscreens, cosmetics; exhibits estrogenic activity.Formule :C18H22ODegré de pureté :99.92%Couleur et forme :White SolidMasse moléculaire :254.37L-Glutamic acid monosodium salt
CAS :L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formule :C5H8NO4·NaDegré de pureté :99.93%Couleur et forme :White Solid CrystallineMasse moléculaire :169.11Levobupivacaine hydrochloride
CAS :Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formule :C18H28N2O·HClDegré de pureté :99.74%Couleur et forme :White Crystalline PowderMasse moléculaire :324.89Kevetrin hydrochloride
CAS :Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potentialFormule :C5H10ClN3SDegré de pureté :99.32% - 99.93%Couleur et forme :SolidMasse moléculaire :179.673-O-Acetyloleanolic acid
CAS :3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells.Formule :C32H50O4Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :498.74PS210
CAS :PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.Formule :C19H15F3O5Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :380.31Ref: TM-T16670
1mg34,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)80,00€10mg102,00€25mg187,00€50mg333,00€100mg495,00€Adaphostin
CAS :Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formule :C24H27NO4Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :393.48Alofanib
CAS :Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.Formule :C19H15N3O6SDegré de pureté :99.53% - 99.81%Couleur et forme :SolidMasse moléculaire :413.4Cyclopiazonic acid
CAS :Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.Formule :C20H20N2O3Degré de pureté :99.27% - 99.80%Couleur et forme :SolidMasse moléculaire :336.38Loganin
CAS :Loganin inhibits Cox-1, suppresses TNF-α, and has antioxidant and anti-melanogenic properties.Formule :C17H26O10Degré de pureté :99.01% - 99.9%Couleur et forme :White PowderMasse moléculaire :390.38(S)-(+)-Ibuprofen
CAS :(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Formule :C13H18O2Degré de pureté :99.51% - 99.86%Couleur et forme :Colourless Crystalline SolidMasse moléculaire :206.28Meloxicam
CAS :Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formule :C14H13N3O4S2Degré de pureté :97.09% - 99.60%Couleur et forme :Light Yellow SolidMasse moléculaire :351.40Tulisokibart
CAS :Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Degré de pureté :98.38% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :143.96 kDaFINO2
CAS :FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formule :C15H28O3Degré de pureté :97.27%Couleur et forme :SoildMasse moléculaire :256.38Socazolimab
CAS :Socazolimab (ZKAB001) is a monoclonal antibody targeting PD-L1 with antitumor activity, used in studies of recurrent or metastatic cervical cancer.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :143.06 kDaAZ5576
CAS :AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].Formule :C21H24FN3O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :385.43Ref: TM-T60152
1mg34,00€5mg75,00€1mL*10mM (DMSO)82,00€10mg107,00€25mg210,00€50mg314,00€100mg449,00€500mg888,00€S3QEL-2
CAS :S3QEL-2 is a site-specific inhibitor of complex III superoxide production with neuroprotective effects.Formule :C19H25N5Degré de pureté :98.28% - 99.58%Couleur et forme :SolidMasse moléculaire :323.44Doxorubicin
CAS :Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formule :C27H29NO11Degré de pureté :99.31%Couleur et forme :Red Crystalline Solid SolidMasse moléculaire :543.52Taurodeoxycholic Acid Sodium Salt
CAS :Produit contrôléApplications Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
References Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),Formule :C26H44NO6S·NaCouleur et forme :Off-WhiteMasse moléculaire :521.69Sodium oleate
CAS :Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium.Formule :C18H33NaO2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :304.44Dracorhodin Perchlorate
CAS :Produit contrôléFormule :C17H15O3·ClO4Couleur et forme :NeatMasse moléculaire :366.75Seribantumab
CAS :Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting cancer cell proliferation.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :143.14 kDaIACS-010759 hydrochloride
CAS :IACS-010759 hydrochloride is an orally potent and selective OXPHOS inhibitor that inhibits proliferation and induces apoptosis AML and solid tumours.Formule :C25H26ClF3N6O4SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :599.03Ref: TM-T27568
1mg50,00€5mg113,00€1mL*10mM (DMSO)150,00€10mg166,00€25mg268,00€50mg395,00€100mg583,00€200mg833,00€Cholesteryl Hemisuccinate
CAS :Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective,Formule :C31H50O4Degré de pureté :97.09% - 99.98%Couleur et forme :White PowderMasse moléculaire :486.73Anticancer agent 43
CAS :Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces
Formule :C14H9FN2O3S2Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :336.36Envafolimab
CAS :Envafolimab (ASC 22) is a humanized antibody targeting PD-L1, with anticancer activity, blocking the PD-L1 and PD-1 interaction.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :80 kDa2′,2′-Difluorodeoxyuridine
CAS :2′,2′-Difluorodeoxyuridine has anticancer activity, and shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.Formule :C9H10F2N2O5Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :264.18GDC 0152
CAS :Produit contrôléApplications GDC 0152 is a peptidomimetic small molecule antagonist of inhibitor of apoptosis (IAP) proteins with antitumor activity.
References Yue, Q., et. al.: Drug Metab. Dispos., 41, 508 (2013)Formule :C25H34N6O3SCouleur et forme :NeatMasse moléculaire :498.64Santalol
CAS :α-Santalol: antibacterial, antioxidant, anti-tumor, antimitotic, and antifungal against Trichophyton rubrum.Formule :C15H24ODegré de pureté :94.41%Couleur et forme :SolidMasse moléculaire :220.35Avasimibe
CAS :Applications Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasimibe is known to induce apoptosis of glioma cell lines as a model of glioblastoma.
References Bemlih, S., et al.: Cancer. BIol. Therap., 9, 1025 (2010); Fahmi, O.A., et al.: Drug. Meta. Disp. 38, 1605 (2010);Formule :C29H43NO4SCouleur et forme :White SolidMasse moléculaire :501.72POMHEX
CAS :Pomhex, a cell-penetrating ENO2 inhibitor, thwarts glycolysis to combat ENO1-deficient tumors.Formule :C17H30NO9PDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :423.4(R)-Muscone
CAS :Produit contrôléApplications (R)-Muscone is a chemical compound that protects PC12 cells against glutamate-induced apoptosis. In addition, its a primary contributor to the odour of musk.
References Yu, L., et. al.: Neurochem. Int., 70, 10 (2014)Formule :C16H30OCouleur et forme :NeatMasse moléculaire :238.41A-1331852
CAS :Produit contrôléApplications A-1331852 is a substituted benzothiazole that can serve as an anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.
References Wang, L., et al.: PCT Int. Appl. WO 2013055897 A1 20130418. Apr 18, 2013Formule :C38H38N6O3SCouleur et forme :NeatMasse moléculaire :658.81Adebrelimab
CAS :Adebrelimab (SHR-1316) is a humanized monoclonal antibody targeting PD-L1 with antitumor activity for the study of solid tumors.Degré de pureté :97.8% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.54 kDaGSK1904529A
CAS :GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Formule :C44H47F2N9O5SDegré de pureté :98.2% - 99.76%Couleur et forme :SolidMasse moléculaire :851.96ARB-272572
CAS :ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.67Ref: TM-T39914
1mg123,00€5mg295,00€1mL*10mM (DMSO)353,00€10mg425,00€25mg712,00€50mg1.035,00€100mg1.485,00€200mg1.998,00€8,9-di-O-Methyl-urolithin C
CAS :Produit contrôléApplications 8,9-di-O-Methyl-urolithin C is a derivative of Urolithin C and is an intestinal microbial metabolite of ellagitannins. It has shown to have inhibitory effects on cell proliferation and apoptosis effects suggesting the potential for reduced risk of colon cancer development when it is found in considerable amounts via consumption of pomegranate juice.
References Kasimsetty, S., et al.: J. Agr. Food Chem., 58, 2180 (2010);Formule :C9H8N2Couleur et forme :NeatMasse moléculaire :144.173Embelin
CAS :Produit contrôléApplications Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embelin also displays contraceptive and pro-apoptotic properties.
References Stasiuk, M. et al.: Glob. J. Biochem., 2, 262 (2011); Brahmeshwari, G. et al.: Adv. Plant Sci., 24, 467 (2011); Hu, R. et al.: Med. Oncol., 28, 1598 (2011);Formule :C17H26O4Couleur et forme :OrangeMasse moléculaire :294.39LCS-1
CAS :LCS-1 is a SOD1 inhibitor and pyridazin-3-one derivative that shows trypanocidal activity at high concentrations.Formule :C11H8Cl2N2ODegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :255.1Ref: TM-T60386
5mg46,00€1mL*10mM (DMSO)49,00€10mg75,00€25mg123,00€50mg173,00€100mg259,00€200mg385,00€Solasodine Hydrochloride
CAS :Produit contrôléApplications Solasodine Hydrochloride enhances the effect of As2O3 in inducing apoptosis in HeLa cell, which is related to its inhibiting telomerase activity in HeLa cells.
References Ai, J., et al.: Chin. J. Endemiol., 30, 279 (2011)Formule :C27H43NO2·HClCouleur et forme :NeatMasse moléculaire :413.64SSK1
CAS :SSK1 is a senescent cell-killing and β-galactosidase-targeting precursor compound that activates phosphorylation levels of p38 MAPK in senescent cells.Formule :C31H34F2N4O18Degré de pureté :98.88% - 99.48%Couleur et forme :SolidMasse moléculaire :788.61Ref: TM-T37450
1mg145,00€5mg334,00€1mL*10mM (DMSO)439,00€10mg505,00€25mg803,00€50mg1.108,00€100mg1.558,00€200mg2.097,00€EasyStep Human GDF15(Growth Differentiation Factor 15) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GDF15, and the Human GDF15 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human GDF15. After TMB substrate solution is added, only those wells that contain Human GDF15 and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human GDF15 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidAzoxystrobin
CAS :Azoxystrobin (Bankit) is a broad-spectrum fungicide blocking electron transfer, causing ROS, apoptosis, and affecting respiration.Formule :C22H17N3O5Degré de pureté :99.82%Couleur et forme :White CrystallineMasse moléculaire :403.39Ionomycin
CAS :Ionomycin is a calcium ionophore and a Ca2+ -binding antibiotic, increases intracellular Ca 2 + to induce cellular responses. High-Quality, Low-Cost!Formule :C41H72O9Degré de pureté :99.54%Couleur et forme :Pale Yellow OilMasse moléculaire :709.01Rabeprazole
CAS :Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells and can be used in the study of gastric ulcers.Formule :C18H21N3O3SDegré de pureté :97.06%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :359.44Scutellarin
CAS :Applications Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.
References Gao, C. et al.: Drug Metab. Dispos., 39, 2034 (2011); Chan, J.Y. et al.: Anticancer Res., 29, 3043 (2009); Wang, C.-Z. et al.: Phytomedicine, 17, 63 (2010);Formule :C21H18O12Couleur et forme :NeatMasse moléculaire :462.36N6-(2-Hydroxyethyl)adenosine
CAS :N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.Formule :C12H17N5O5Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :311.29trans-1-Cinnamylpiperazine
CAS :Produit contrôléApplications trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.
References Brossard, D. et al.: Eur. J. Med. Chem., 45, 2912 (2010);Formule :C13H18N2Couleur et forme :NeatMasse moléculaire :202.15N1-Acetylspermidine hydrochloride
CAS :N1-Acetylspermidine HCl, an acetyl spermidine derivative, boosts polyamine oxidase levels in colorectal adenocarcinomas.Formule :C9H23Cl2N3ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :260.2Selumetinib sulfate
CAS :Selumetinib sulfate (AZD6244 sulfate) is a MEK1/2 inhibitor that inhibits MEK1/2 phosphorylation.Formule :C17H17BrClFN4O7SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :555.76
