Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5599 produits trouvés pour "Apoptose"
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SAHA-OH
CAS :<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Formule :C15H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.35Dabuzalgron HCl
CAS :<p>Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.</p>Formule :C12H17Cl2N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.255HPP-33
CAS :<p>5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.</p>Formule :C20H21NO3Couleur et forme :SolidMasse moléculaire :323.39Telomerase-IN-5
CAS :<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Formule :C22H20N4OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.55KF24345
CAS :<p>KF24345 is an inhibitor of adenosine uptake.</p>Formule :C31H38N6O5Couleur et forme :SolidMasse moléculaire :574.67ATB-337
CAS :<p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>Formule :C23H15Cl2NO2S3Couleur et forme :SolidMasse moléculaire :504.47SKLB70326
CAS :<p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>Formule :C15H13N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.35DPQZ
CAS :<p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>Formule :C20H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.37PS121912
CAS :<p>PS121912 is a potent and selective inhibitor of VDR-coactivator.</p>Formule :C24H21F3N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.43A 410099.1
CAS :<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1BLM-IN-1
CAS :<p>BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.</p>Formule :C28H35FN4OCouleur et forme :SolidMasse moléculaire :462.6RIPK1-IN-13
CAS :<p>RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.</p>Formule :C21H20ClN3O3Couleur et forme :SolidMasse moléculaire :397.85MI-1061
CAS :<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Formule :C30H26Cl2FN3O4Couleur et forme :SolidMasse moléculaire :582.45Vin-F03
CAS :<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49Propiomazine
CAS :<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Formule :C20H24N2OSDegré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :340.48MI-389
CAS :<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Formule :C35H35FN6O6Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :654.69Apoptosis inducer 8
CAS :<p>Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used</p>Formule :C29H22ClN5O2Couleur et forme :SolidMasse moléculaire :507.97CCT373567
CAS :<p>CCT373567 is a potent degrader of the transcriptional repressor BCL6 (IC50: 2.9 nM) and exhibits anti-proliferative effects.</p>Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547Norartocarpetin
CAS :<p>Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24SHP2-IN-8
CAS :<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35FL3
CAS :<p>FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.</p>Formule :C25H23BrO5Couleur et forme :SolidMasse moléculaire :483.35Flupenthixol
CAS :<p>Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.</p>Formule :C23H25F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.52HDAC-IN-39
CAS :<p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>Formule :C27H26N4O4SCouleur et forme :SolidMasse moléculaire :502.58Psammaplysene A
CAS :<p>Psammaplysene A is a FOXO1a nuclear export inhibitor.</p>Formule :C27H35Br4N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :769.23-ATA
CAS :<p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>Formule :C13H10N2SCouleur et forme :SolidMasse moléculaire :226.3Darinaparsin
CAS :<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Formule :C12H22AsN3O6SCouleur et forme :SolidMasse moléculaire :411.31BMS-1166 hydrochloride
CAS :<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57CMLD012612
CAS :<p>CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).</p>Formule :C31H33N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :559.61EGFR-IN-57
CAS :<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Formule :C22H15N3O2SCouleur et forme :SolidMasse moléculaire :385.44BMS-200
CAS :BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5IV-23
CAS :<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Formule :C18H18BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.24STAT3-IN-3
CAS :<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Formule :C27H26BrN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.48OT-82
CAS :<p>OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.</p>Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Nimustine
CAS :<p>Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.</p>Formule :C9H13ClN6O2Couleur et forme :SolidMasse moléculaire :272.69PCAF-IN-2
CAS :<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Formule :C10H7F3N6Couleur et forme :SolidMasse moléculaire :268.2Antitumor agent-70
CAS :<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39HS56
CAS :<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75TNF-α-IN-18
CAS :<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formule :C16H7ClF2O4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :336.67IST5-002
CAS :<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Formule :C17H20N5O7PDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :437.34RDR03871
CAS :<p>RDR03871 is an MDM2 inhibitor.</p>Formule :C18H16ClF3N6Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :408.81ZINC69391
CAS :<p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>Formule :C14H14F3N5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :309.29LG190178
CAS :<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Formule :C28H42O5Couleur et forme :SolidMasse moléculaire :458.63Apoptotic agent-1
CAS :<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Formule :C12H6ClN5O2SCouleur et forme :SolidMasse moléculaire :319.73VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Formule :C26H20Cl2F3N5O3S2Couleur et forme :SolidMasse moléculaire :642.5Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formule :C29H34N2O15Couleur et forme :SolidMasse moléculaire :650.58Merck-22-6
CAS :<p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>Formule :C40H43N7O2Couleur et forme :SolidMasse moléculaire :653.82iMAC2
CAS :<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Formule :C19H20Br2FN3Couleur et forme :SolidMasse moléculaire :469.19GL-331
CAS :<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Formule :C27H24N2O9Couleur et forme :SolidMasse moléculaire :520.49GZD856
CAS :<p>GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.</p>Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.56CDK8/19-IN-1
CAS :<p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>Formule :C19H18N4O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.5SMI-6860766
CAS :<p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>Formule :C15H11BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.61Mitoguazone
CAS :<p>Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.</p>Formule :C5H12N8Degré de pureté :97.47% - 98%Couleur et forme :SolidMasse moléculaire :184.2BPTQ
CAS :<p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>Formule :C17H16N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.4Anticancer agent 57
CAS :<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Formule :C20H21Cl2NO2Couleur et forme :SolidMasse moléculaire :378.29Filanesib
CAS :<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Formule :C20H22F2N4O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.48DJ001
CAS :<p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>Formule :C15H12N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.27MDM2-IN-1
CAS :<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Formule :C23H21Cl2FN2O3Couleur et forme :SolidMasse moléculaire :463.33VEGFR-2-IN-19
CAS :<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formule :C21H19N3O2Couleur et forme :SolidMasse moléculaire :345.39YH-306
CAS :<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Formule :C19H18N2O2Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :306.36Imofinostat
CAS :<p>Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.</p>Formule :C17H16N2O4SCouleur et forme :SolidMasse moléculaire :344.38HMBPP triammonium
CAS :<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Formule :C5H15NO8P2Couleur et forme :SolidMasse moléculaire :279.122MCL-1/BCL-2-IN-3
CAS :<p>MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.</p>Formule :C27H25BrN2O5SCouleur et forme :SolidMasse moléculaire :569.47PERK-IN-3
CAS :<p>PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).</p>Formule :C22H16F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.38MG-115
CAS :<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Formule :C25H39N3O5Degré de pureté :97.12%Couleur et forme :White PowderMasse moléculaire :461.59c-Met-IN-9
CAS :<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Formule :C25H19F2N5O3Couleur et forme :SolidMasse moléculaire :475.45Apoptosis inducer 6
CAS :<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Formule :C27H26N4O3SCouleur et forme :SolidMasse moléculaire :486.59RET-IN-6
CAS :<p>RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).</p>Formule :C30H29N7Couleur et forme :SolidMasse moléculaire :487.6TL02-59 dihydrochloride
CAS :<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Formule :C32H36Cl2F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :682.56SKF1
CAS :<p>SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.</p>Formule :C23H37ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.01BCL6-IN-8c
CAS :<p>BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent</p>Formule :C20H20ClN3O5Couleur et forme :SolidMasse moléculaire :417.84eIF4A3-IN-2
CAS :<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Formule :C25H19Br2ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71SAR125844
CAS :<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Formule :C25H23FN8O2S2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :550.63WJ35435
CAS :<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Formule :C20H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.4(1S,2S)-Bortezomib
CAS :<p>(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.</p>Formule :C19H25BN4O4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :384.24Ivaltinostat
CAS :<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54TRAF-STOP inhibitor 6877002
CAS :<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32TRK-IN-23
CAS :<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Formule :C20H17FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.37Tubulin polymerization-IN-24
CAS :<p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>Formule :C22H16O3Couleur et forme :SolidMasse moléculaire :328.36TP-472
CAS :<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Formule :C20H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38HX 630
CAS :<p>RXR agonist</p>Formule :C28H27NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.58GW7845
CAS :<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Formule :C29H28N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.54Metoprolol fumarate
CAS :<p>Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.</p>Formule :C34H54N2O10Couleur et forme :SolidMasse moléculaire :650.8Shield-2
CAS :<p>Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.</p>Formule :C35H51N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.8Anticancer agent 77
CAS :<p>Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.</p>Formule :C25H30BrN7Couleur et forme :SolidMasse moléculaire :508.46Lemuteporfin
CAS :<p>Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.</p>Formule :C44H48N4O10Degré de pureté :97.14% - 99.44%Couleur et forme :SolidMasse moléculaire :792.87BS-181
CAS :<p>BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.</p>Formule :C22H32N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.53D-Cl-amidine
CAS :<p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78HBV-IN-23
CAS :<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formule :C25H27N3O3SCouleur et forme :SolidMasse moléculaire :449.57Nec-3a
CAS :<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formule :C21H18F4N2O4Couleur et forme :SolidMasse moléculaire :438.37RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formule :C32H33FN6O4Couleur et forme :SolidMasse moléculaire :584.64AG-024322
CAS :<p>AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.</p>Formule :C23H20F2N6Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :418.44DAT-230
CAS :<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Formule :C20H21NO2SCouleur et forme :SolidMasse moléculaire :339.45ZDLD13
CAS :<p>ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.</p>Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33Tubulin polymerization-IN-13
CAS :<p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>Formule :C20H21NO6Couleur et forme :SolidMasse moléculaire :371.38Topoisomerase I inhibitor 3
CAS :<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formule :C18H14FNO3Couleur et forme :SolidMasse moléculaire :311.31PARP14 inhibitor H10
CAS :<p>PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM</p>Formule :C24H27N7O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.58GKK1032B
CAS :<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formule :C32H39NO4Couleur et forme :SolidMasse moléculaire :501.66DRAK2-IN-1
CAS :<p>Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).</p>Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41OXPHOS-IN-1
CAS :<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Formule :C19H29N3O6S2Couleur et forme :SolidMasse moléculaire :459.58Benpyrine
CAS :<p>Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.</p>Formule :C16H16N6OCouleur et forme :SolidMasse moléculaire :308.34
