Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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LW6
CAS :LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Ref: TM-T3494
2mg44,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€Diosgenin glucoside
CAS :Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis
Formule :C33H52O8Degré de pureté :97.17% - 99.44%Couleur et forme :SolidMasse moléculaire :576.76MSC 2032964A
CAS :MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.
Formule :C16H13F3N6ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :362.31Ref: TM-T33514
1mg84,00€2mg97,00€5mg158,00€10mg240,00€25mg393,00€50mg560,00€100mg753,00€200mg1.035,00€MG 149
CAS :MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formule :C22H28O3Degré de pureté :98.69% - 99.86%Couleur et forme :SolidMasse moléculaire :340.46Ref: TM-T6584
1mg50,00€2mg71,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg167,00€25mg308,00€50mg492,00€100mg708,00€GSK 3 Inhibitor IX
CAS :GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.Formule :C16H10BrN3O2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :356.17Ref: TM-T1917
1mg42,00€2mg52,00€5mg78,00€1mL*10mM (DMSO)86,00€10mg96,00€25mg216,00€50mg389,00€100mg577,00€500mg1.234,00€Tomatine
CAS :Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formule :C50H83NO21Degré de pureté :98.42% - 99.94%Couleur et forme :White To Light YellowMasse moléculaire :1034.19MG-101
CAS :MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formule :C20H37N3O4Degré de pureté :98% - ≥98%Couleur et forme :SolidMasse moléculaire :383.53Momelotinib
CAS :Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formule :C23H22N6O2Degré de pureté :97.07% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T1849
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg89,00€25mg158,00€50mg245,00€100mg385,00€200mg592,00€Oleic acid
CAS :Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.Formule :C18H34O2Degré de pureté :97.14% - 99.91%Couleur et forme :Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Masse moléculaire :282.46RA-9
CAS :RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.Formule :C19H15N3O5Degré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :365.34LY2857785
CAS :LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).Formule :C26H36N6ODegré de pureté :99.68%Couleur et forme :Solid PowderMasse moléculaire :448.6Ref: TM-TQ0060
1mg50,00€2mg71,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg334,00€50mg537,00€100mg863,00€Niraparib
CAS :Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39Ref: TM-T3231
5mg57,00€1mL*10mM (DMSO)63,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€Citronellyl acetate
CAS :Citronellyl acetate is a natural productFormule :C12H22O2Degré de pureté :98%Couleur et forme :LiquidMasse moléculaire :198.30AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95Tiplaxtinin
CAS :Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€Sirtinol
CAS :Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6671
2mg40,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg88,00€25mg170,00€50mg324,00€100mg482,00€500mg1.063,00€Toyocamycin
CAS :Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (Formule :C12H13N5O4Degré de pureté :98.1% - 99.44%Couleur et forme :SolidMasse moléculaire :291.26Ref: TM-T17143
5mg44,00€1mL*10mM (DMSO)48,00€10mg62,00€25mg107,00€50mg192,00€100mg334,00€500mg782,00€Icaritin
CAS :Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formule :C21H20O6Degré de pureté :97.69% - 99.76%Couleur et forme :SolidMasse moléculaire :368.38Dinoprost methoxyamine
CAS :Dinoprost methoxyamine is a hormone.Formule :C21H39NO6Couleur et forme :SolidMasse moléculaire :401.544Se-Methylselenocysteine
CAS :Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.Formule :C4H9NO2SeDegré de pureté :99.49% - 99.87%Couleur et forme :White To Slightly Yellow PowderMasse moléculaire :182.08Angiotensin II human acetate
CAS :Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.Formule :C52H75N13O14Degré de pureté :98.89% - 99.78%Couleur et forme :SolidMasse moléculaire :1106.2PCI-34051
CAS :PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).Formule :C17H16N2O3Degré de pureté :97.219% - 98.29%Couleur et forme :SolidMasse moléculaire :296.32Ref: TM-T6325
5mg57,00€1mL*10mM (DMSO)63,00€10mg90,00€25mg175,00€50mg334,00€100mg537,00€500mg1.134,00€(Rac)-Benpyrine
CAS :(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formule :C16H16N6ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€TVB-3166
CAS :TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).Formule :C24H24N4ODegré de pureté :99.53% - 99.57%Couleur et forme :SolidMasse moléculaire :384.47Ref: TM-T17180
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg195,00€50mg334,00€100mg500,00€HS-173
CAS :HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).Formule :C21H18N4O4SDegré de pureté :99.33% - 99.64%Couleur et forme :SolidMasse moléculaire :422.46Ref: TM-T2308
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg77,00€25mg128,00€50mg200,00€100mg296,00€200mg425,00€Fidaxomicin
CAS :Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.Formule :C52H74Cl2O18Degré de pureté :99.76% - 99.82%Couleur et forme :SolidMasse moléculaire :1058.04Ref: TM-T6194
10mg46,00€1mL*10mM (DMSO)52,00€25mg56,00€50mg77,00€100mg117,00€200mg167,00€500mg268,00€1g414,00€Linderalactone
CAS :1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T5S1897
1mg43,00€5mg84,00€1mL*10mM (DMSO)102,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€Sophocarpine
CAS :Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formule :C15H22N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :246.35Parthenolide
CAS :Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formule :C15H20O3Degré de pureté :98.19% - 99.46%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :248.32Capmatinib
CAS :Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Formule :C23H17FN6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :412.42Ref: TM-T1963
5mg48,00€1mL*10mM (DMSO)50,00€10mg63,00€25mg78,00€50mg90,00€100mg124,00€200mg158,00€500mg255,00€EPZ004777 hydrochloride
CAS :EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formule :C28H42ClN7O4Couleur et forme :SolidMasse moléculaire :576.13Citric acid
CAS :Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits, a food additive and a natural preservative. High-Quality, Low-Cost!Formule :C6H8O7Degré de pureté :98.88%Couleur et forme :White Solid CrystallineMasse moléculaire :192.12Penicillic acid
CAS :Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formule :C8H10O4Degré de pureté :98%Couleur et forme :Needles From Petroleum Ether Slight Yellow PowderMasse moléculaire :170.16Everolimus
CAS :Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.
Formule :C53H83NO14Degré de pureté :97.76% - 99.78%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.22Ursonic Acid
CAS :Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton.Formule :C30H46O3Degré de pureté :98.90% - >99.99%Couleur et forme :SolidMasse moléculaire :454.68Puromycin aminonucleoside
CAS :Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.Formule :C12H18N6O3Degré de pureté :99.85% - 99.9%Couleur et forme :SolidMasse moléculaire :294.31Salermide
CAS :Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.Formule :C26H22N2O2Degré de pureté :97.09% - 99.55%Couleur et forme :SolidMasse moléculaire :394.47PP1
CAS :PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formule :C16H19N5Degré de pureté :99% - 99.88%Couleur et forme :Off-White To Grey SolidMasse moléculaire :281.36Ref: TM-T6196
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)89,00€10mg112,00€25mg190,00€50mg268,00€100mg421,00€500mg945,00€LY2409881 trihydrochloride
CAS :LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.Formule :C24H32Cl4N6OSDegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :594.43SCR7 pyrazine
CAS :SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formule :C18H12N4OSDegré de pureté :98.72% - 99.85%Couleur et forme :SolidMasse moléculaire :332.38Ref: TM-T1724
1mg39,00€2mg50,00€5mg79,00€1mL*10mM (DMSO)79,00€10mg120,00€25mg258,00€50mg408,00€100mg588,00€DB1976 dihydrochloride
CAS :DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.Formule :C20H18Cl2N8SeDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :520.28Avotaciclib sulfate
CAS :Avotaciclib sulfate is a cyclin-dependent kinase inhibitor and antineoplastic.Formule :C13H13N7O5SCouleur et forme :SolidMasse moléculaire :379.35Tolcapone
CAS :Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopaFormule :C14H11NO5Degré de pureté :98.93% - 99.68%Couleur et forme :SolidMasse moléculaire :273.24Ref: TM-T6708
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg82,00€50mg92,00€100mg124,00€200mg170,00€500mg284,00€Benzydamine
CAS :Benzydamine: analgesic, antipyretic, anti-inflammatory; reduces pain, swelling, aids healing post-surgery/trauma.Formule :C19H23N3ODegré de pureté :97.872% - 98.34%Couleur et forme :SolidMasse moléculaire :309.41Tomivosertib
CAS :Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.Formule :C17H20N6O2Degré de pureté :97.34% - 99.72%Couleur et forme :SolidMasse moléculaire :340.383-Nitropropanoic acid
CAS :3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.Formule :C3H5NO4Degré de pureté :98.35% - 99.94%Couleur et forme :Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Masse moléculaire :119.08AX-024 hydrochloride
CAS :AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of IL-6, TNFα, IFN-γ, IL-10 and IL-17A.Formule :C21H23ClFNO2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :375.87Ref: TM-T4403
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg75,00€25mg145,00€50mg260,00€100mg485,00€200mg690,00€EGFR-IN-12
CAS :EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formule :C21H18F3N5ODegré de pureté :98.3% - 99.76%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5168
1mg82,00€5mg159,00€1mL*10mM (DMSO)168,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€NVP-CGM097
CAS :NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).Formule :C38H47ClN4O4Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :659.26Ref: TM-TQ0231
1mg82,00€5mg195,00€1mL*10mM (DMSO)284,00€10mg324,00€25mg492,00€50mg647,00€100mg893,00€Cynaroside
CAS :Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.Formule :C21H20O11Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :448.38Ref: TM-T3376
1mg34,00€5mg71,00€1mL*10mM (DMSO)80,00€10mg98,00€25mg192,00€50mg339,00€100mg505,00€200mg717,00€
