Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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PHA-767491
CAS :<p>PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.</p>Formule :C12H11N3ODegré de pureté :99.49% - >99.99%Couleur et forme :SolidMasse moléculaire :213.24Sarecycline free base
CAS :<p>Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.</p>Formule :C24H29N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.5Seliciclib
CAS :<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Formule :C19H26N6ODegré de pureté :97.15% - 99.89%Couleur et forme :White To Off-White SolidMasse moléculaire :354.45InhA-IN-2
CAS :<p>N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.</p>Formule :C16H15ClN2O2S2Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :366.89Protein kinase inhibitor 6
CAS :<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formule :C13H9FN2SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :244.29R-IMPP
CAS :<p>R-IMPP is an inhibitor of PCSK9 translation.</p>Formule :C24H27N3O2Degré de pureté :99.47% - 99.85%Couleur et forme :SolidMasse moléculaire :389.496-Mercaptopurine hydrate
CAS :<p>6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.</p>Formule :C5H6N4OSDegré de pureté :97.54% - 99.14%Couleur et forme :Light Yellow Crystalline PowderMasse moléculaire :170.19Mogroside I E1
CAS :<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Formule :C36H62O9Degré de pureté :98.62% - 99.71%Couleur et forme :SolidMasse moléculaire :638.87TH5487
CAS :<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Formule :C19H18BrIN4O2Degré de pureté :98.38% - 98.73%Couleur et forme :SolidMasse moléculaire :541.18Ro3280
CAS :<p>Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).</p>Formule :C27H35F2N7O3Degré de pureté :97.1% - >99.99%Couleur et forme :SolidMasse moléculaire :543.61360A
CAS :<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formule :C27H23N5O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.5LIMK-IN-22j
CAS :<p>LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.</p>Formule :C20H21BrN8Degré de pureté :99.165%Couleur et forme :SolidMasse moléculaire :453.34BI-847325
CAS :<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formule :C29H28N4O2Degré de pureté :97.13% - 97.54%Couleur et forme :SolidMasse moléculaire :464.56BS194
CAS :<p>BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.</p>Formule :C20H27N5O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :385.46CWHM-12
CAS :<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formule :C26H32BrN5O6Degré de pureté :98.05% - 99.83%Couleur et forme :SolidMasse moléculaire :590.47CRT0066854
CAS :<p>CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.</p>Formule :C24H25N5SCouleur et forme :SolidMasse moléculaire :415.55CCG-222740
CAS :<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Formule :C23H19ClF2N2O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :444.86Ganciclovir sodium
CAS :<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22Aplidine
CAS :<p>Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).</p>Formule :C57H87N7O15Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :1110.34Aurora kinase inhibitor-2
CAS :<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Formule :C23H20N4O3Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :400.43Activated Protein C (390-404), human acetate
<p>Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.</p>Formule :C93H134N22O25Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :1960.19Clevudine
CAS :<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Formule :C10H13FN2O5Degré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :260.22CID755673
CAS :<p>CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.</p>Formule :C12H11NO3Degré de pureté :97.68% - 99.84%Couleur et forme :SolidMasse moléculaire :217.22MC180295
CAS :<p>MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.</p>Formule :C17H18N4O3SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :358.41Favipiravir
CAS :<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Formule :C5H4FN3O2Degré de pureté :97.32% - 99.90%Couleur et forme :SolidMasse moléculaire :157.1Cyclo(-RGDfK)
CAS :<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formule :C27H41N9O7Degré de pureté :95.29% - >99.99%Couleur et forme :SolidMasse moléculaire :603.67AZ3146
CAS :<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Formule :C24H32N6O3Degré de pureté :97.84% - >99.99%Couleur et forme :SolidMasse moléculaire :452.55Metoprine
CAS :<p>Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.</p>Formule :C11H10Cl2N4Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :269.13CID44216842
CAS :<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Formule :C22H20BrN3O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.38SNS-314 Mesylate
CAS :<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Formule :C18H15ClN6OS2·CH4O3SDegré de pureté :99.44% - 99.92%Couleur et forme :SolidMasse moléculaire :527.04DHFR-IN-3
CAS :<p>DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.</p>Formule :C8H7BrN4Degré de pureté :99.521% - 99.65%Couleur et forme :SolidMasse moléculaire :239.07NSAH
CAS :<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Formule :C18H14N2O3Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :306.32M2N12
CAS :<p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>Formule :C20H16ClN5O2Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :393.83HAMNO
CAS :<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Formule :C17H13NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :263.29TH287
CAS :<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Formule :C11H10Cl2N4Degré de pureté :97.73% - 99%Couleur et forme :SolidMasse moléculaire :269.136-AZATHYMINE
CAS :<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Formule :C4H5N3O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :127.13-Methylcytidine
CAS :<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Formule :C10H15N3O5Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :257.24IMT1B
CAS :<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Formule :C24H21ClFNO6Degré de pureté :98.26% - 99.83%Couleur et forme :SolidMasse moléculaire :473.88Irigenin
CAS :<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31(1E)-CFI-400437 dihydrochloride
CAS :<p>(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.</p>Formule :C29H30Cl2N6O2Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :565.5Ganciclovir hydrate
CAS :<p>Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.</p>Formule :C9H15N5O5Couleur et forme :SolidMasse moléculaire :273.249TH-257
CAS :<p>TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).</p>Formule :C24H26N2O3SDegré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :422.54SR18662
<p>SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.</p>Formule :C16H19Cl2N3O4SDegré de pureté :98.97% - 99.2%Couleur et forme :SolidMasse moléculaire :420.31CRT0044876
CAS :<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Formule :C9H6N2O4Degré de pureté :98.27% - 98.98%Couleur et forme :Brown PowderMasse moléculaire :206.15EHop-016
CAS :<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.555-Fluoroorotic acid
CAS :<p>5-Fluoroorotic acid is an inhibitor of thymidylate synthase.</p>Formule :C5H3FN2O4Degré de pureté :99.7% - >99.99%Couleur et forme :White To Pale Yellow PowderMasse moléculaire :174.09RI-2
CAS :<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Formule :C21H18Cl2N2O4Degré de pureté :99.63% - 99.86%Couleur et forme :SolidMasse moléculaire :433.28Quarfloxin
CAS :<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Formule :C35H33FN6O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :604.67AS2863619
CAS :<p>AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.</p>Formule :C16H14Cl2N8ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :405.242'-Fluoro-2'-Deoxyadenosine
CAS :<p>2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).</p>Formule :C10H12FN5O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :269.23BRD9876
CAS :<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Formule :C16H14N2Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :234.3Ro5-3335
CAS :<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Formule :C13H10ClN3ODegré de pureté :99.42% - 99.87%Couleur et forme :SolidMasse moléculaire :259.69XL228
CAS :<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Tozasertib
CAS :<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.59APY29
CAS :<p>APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.</p>Formule :C17H16N8Degré de pureté :96.51% - 98.46%Couleur et forme :SolidMasse moléculaire :332.36SAR-020106
CAS :<p>SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.</p>Formule :C19H19ClN6ODegré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :382.85CID-797718
CAS :<p>CID-797718 is a protein kinase D1 (PKD1) inhibitor.</p>Formule :C12H11NO3Degré de pureté :98.91% - 99.21%Couleur et forme :SolidMasse moléculaire :217.22Tipiracil hydrochloride
CAS :<p>Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).</p>Formule :C9H12Cl2N4O2Degré de pureté :98.13% - ≥95%Couleur et forme :SolidMasse moléculaire :279.12Lurbinectedin
CAS :<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Formule :C41H44N4O10SDegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :784.87THZ2
CAS :<p>THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).</p>Formule :C31H28ClN7O2Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :566.05Voruciclib
CAS :<p>Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.</p>Formule :C22H19ClF3NO5Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :469.84Pyrintegrin
CAS :<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formule :C23H25N5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :451.54GSK-923295
CAS :<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Formule :C32H38ClN5O4Degré de pureté :96.22% - 98.02%Couleur et forme :SolidMasse moléculaire :592.13P18IN011
CAS :<p>P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).</p>Formule :C15H12N2O5SDegré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :332.3310074-A4
CAS :<p>10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from</p>Formule :C18H14Cl2N2O3SDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :409.29Madrasin
CAS :<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Formule :C16H17N5O2Degré de pureté :99.06% - 99.61%Couleur et forme :SolidMasse moléculaire :311.34BCH001
CAS :<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Formule :C20H15F3N2O5Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :420.34Trimethoprim sulfate
CAS :<p>Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.</p>Formule :C28H38N8O10SCouleur et forme :SolidMasse moléculaire :678.72Dimethylenastron
CAS :<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Formule :C16H18N2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :302.39SCH900776 (S-isomer)
CAS :<p>SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).</p>Formule :C15H18BrN7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :376.25THZ531
CAS :<p>THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).</p>Formule :C30H32ClN7O2Degré de pureté :97.17% - 99.86%Couleur et forme :SolidMasse moléculaire :558.07Senexin B
CAS :<p>Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).</p>Formule :C27H26N6ODegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :450.53RK33
CAS :<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Formule :C23H20N6O3Degré de pureté :99.04% - 99.72%Couleur et forme :SolidMasse moléculaire :428.44WNK463
CAS :<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Formule :C21H24F3N7O2Degré de pureté :>99.99% - ≥95%Couleur et forme :SolidMasse moléculaire :463.46N2-Methylguanosine
CAS :<p>N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's</p>Formule :C11H15N5O5Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :297.27BIO-1211
CAS :<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8Levofloxacin hydrochloride
CAS :<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.8dGTP
CAS :<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Formule :C10H16N5O13P3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :507.18Triazavirin
CAS :<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Formule :C5H7N6NaO5SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :286.2T-5224
CAS :<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Formule :C29H27NO8Degré de pureté :97.88% - 99.29%Couleur et forme :SolidMasse moléculaire :517.53KIRA6
CAS :<p>KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.</p>Formule :C28H25F3N6ODegré de pureté :97.91%Couleur et forme :SolidMasse moléculaire :518.53PRT4165
CAS :<p>PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.</p>Formule :C15H9NO2Degré de pureté :98.91% - 99.6%Couleur et forme :SolidMasse moléculaire :235.24BS-181 hydrochloride
CAS :<p>BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.</p>Formule :C22H32N6·HClDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :416.99CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Formule :C27H29Cl2N7O2SCouleur et forme :SolidMasse moléculaire :586.54Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.712,2'-Anhydrouridine
CAS :<p>2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.</p>Formule :C9H10N2O5Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :226.19Leukadherin-1
CAS :<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Formule :C22H15NO4S2Degré de pureté :98.49% - 98.93%Couleur et forme :SolidMasse moléculaire :421.49GSK180736A
CAS :<p>GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).</p>Formule :C19H16FN5O2Degré de pureté :98.38% - 98.98%Couleur et forme :SolidMasse moléculaire :365.36Gadodiamide
CAS :<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Formule :C16H26GdN5O8Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :573.66K858 (Racemic)
CAS :<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Formule :C13H15N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.345-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS :<p>5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.</p>Formule :C8H13N3SDegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :183.27Folinic acid calcium hydrate
CAS :<p>Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.</p>Formule :C20H23CaN7O8Couleur et forme :SolidMasse moléculaire :529.523Sovilnesib
CAS :<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Formule :C26H34F2N6O4SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :564.65GJ103 sodium salt
CAS :<p>GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.</p>Formule :C16H13N4NaO3SDegré de pureté :99.70% - 99.91%Couleur et forme :SolidMasse moléculaire :364.36TAK-960 dihydrochloride
<p>TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.</p>Formule :C27H36Cl2F3N7O3Couleur et forme :SolidMasse moléculaire :634.52Spermine tetrahydrochloride
CAS :<p>Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.</p>Formule :C10H26N4·4HClDegré de pureté :99.75% - 99.82%Couleur et forme :SolidMasse moléculaire :348.189-Ethylguanine
CAS :<p>9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.</p>Formule :C7H9N5ODegré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :179.18RAD51-IN-1
CAS :<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Formule :C22H16ClN3ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :373.83CBFβ Inhibitor
CAS :<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Formule :C12H14N2OSDegré de pureté :96.50%Couleur et forme :SolidMasse moléculaire :234.32NITD-2
CAS :<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Formule :C23H19N3O4SDegré de pureté :98.03% - 99.46%Couleur et forme :SolidMasse moléculaire :433.48Abemaciclib methanesulfonate
CAS :<p>Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).</p>Formule :C27H32F2N8·CH4O3SDegré de pureté :98.69% - 99.44%Couleur et forme :SolidMasse moléculaire :602.7BUR1
CAS :<p>BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.</p>Formule :C16H17N5Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :279.34NSC23005 Sodium
CAS :<p>NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.</p>Formule :C13H16NNaO4SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :305.32Monastrol
CAS :<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Formule :C14H16N2O3SDegré de pureté :98.02% - 98.59%Couleur et forme :SolidMasse moléculaire :292.35AUZ 454
CAS :<p>AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.</p>Formule :C24H26F3N7O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :501.5CX-5461
CAS :<p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C27H27N7O2SDegré de pureté :95.44% - 99.25%Couleur et forme :SolidMasse moléculaire :513.61Pipobroman
CAS :<p>Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.</p>Formule :C10H16Br2N2O2Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :356.05BVDV-IN-1
CAS :<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Formule :C20H22N4ODegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :334.41PND-1186
CAS :<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.52-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS :<p>2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.</p>Formule :C6H6N4ODegré de pureté :99.21% - 99.42%Couleur et forme :SolidMasse moléculaire :150.14Myoseverin
CAS :<p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>Formule :C24H28N6O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :432.52OSU-T315
CAS :<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59HMN-176
CAS :<p>HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).</p>Formule :C20H18N2O4SDegré de pureté :98.92% - 98.99%Couleur et forme :SolidMasse moléculaire :382.43PTC-209
CAS :<p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>Formule :C17H13Br2N5OSDegré de pureté :99.43% - 99.887%Couleur et forme :SolidMasse moléculaire :495.19Antitumor agent-152
CAS :<p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>Formule :C17H19N5O2S2Degré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :389.5TC-E 5003
CAS :<p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>Formule :C16H14Cl2N2O4SDegré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :401.26PHA-680632
CAS :<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formule :C28H35N7O2Degré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :501.62MK-8745
CAS :<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formule :C20H19ClFN5OSDegré de pureté :99.09% - 99.79%Couleur et forme :SolidMasse moléculaire :431.91Purvalanol B
CAS :<p>Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)</p>Formule :C20H25ClN6O3Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :432.9C/EBPα inducer 1
CAS :<p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>Formule :C20H12FN3O4Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :377.33VPC-80051 racemate
CAS :<p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>Formule :C16H13F2N3ODegré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :301.29HALOFUGINONE LACTATE
CAS :<p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>Formule :C19H23BrClN3O6Degré de pureté :99.70% - 99.96%Couleur et forme :SolidMasse moléculaire :504.8WEE1-IN-3
CAS :<p>WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.</p>Formule :C28H31N7O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :497.59CB-6644
CAS :<p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>Formule :C29H34ClFN4O5Degré de pureté :96.33% - 99.85%Couleur et forme :SolidMasse moléculaire :573.062-Chloropyrazine
CAS :<p>2-Chloropyrazine is used in chemical industry.</p>Formule :C4H3ClN2Degré de pureté :98.98% - 99.89%Couleur et forme :Clear Colorless To Yellowish LiquidMasse moléculaire :114.53ARQ 621
CAS :<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Formule :C28H24Cl2FN5O2Degré de pureté :97.01% - 98.38%Couleur et forme :SolidMasse moléculaire :552.43Bredinin aglycone
CAS :<p>Bredinin aglycone (SM-108) is a purine nucleotide analog.</p>Formule :C4H5N3O2Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :127.1Palbociclib monohydrochloride
CAS :<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Formule :C24H29N7O2·HClDegré de pureté :99.73% - >99.99%Couleur et forme :SolidMasse moléculaire :483.99Nolatrexed
CAS :<p>Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.</p>Formule :C14H12N4OSDegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :284.34Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
<p>Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation</p>Formule :C76H121N19O25SDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :1732.95Eptifibatide acetate (148031-34-9 free base)
CAS :<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formule :C35H49N11O9S2·xC2H4O2Degré de pureté :99.7% - 99.87%Couleur et forme :SolidMasse moléculaire :831.96 (free base)roxifiban
CAS :<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formule :C21H29N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.48PTC-209 hydrobromide
CAS :<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formule :C17H13Br2N5OS·HBrDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :576.1CVT-313
CAS :<p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>Formule :C20H28N6O3Degré de pureté :97.46% - 97.97%Couleur et forme :SolidMasse moléculaire :400.47YKL-5-124
CAS :<p>YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays</p>Formule :C28H33N7O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :515.61GW779439X
CAS :<p>GW779439X is an inhibitor of CDK.</p>Formule :C22H21F3N8Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :454.45KB-0742 dihydrochloride
CAS :<p>KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.</p>Formule :C16H27Cl2N5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :360.33Besifloxacin Hydrochloride
CAS :<p>Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.</p>Formule :C19H21ClFN3O3·HClDegré de pureté :99.20%Couleur et forme :Pale Yellow SolidMasse moléculaire :430.3TH588
CAS :<p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>Formule :C13H12Cl2N4Degré de pureté :96.05% - 99.82%Couleur et forme :SolidMasse moléculaire :295.17LP-935509
CAS :<p>LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.</p>Formule :C20H24N6O3Degré de pureté :98.78% - 99.64%Couleur et forme :SolidMasse moléculaire :396.44Raltitrexed
CAS :<p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>Formule :C21H22N4O6SDegré de pureté :98.99% - 99.29%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :458.49AMG 900
CAS :<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formule :C28H21N7OSDegré de pureté :98.4% - 99.51%Couleur et forme :SolidMasse moléculaire :503.58MKC3946
CAS :<p>MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.</p>Formule :C21H20N2O3SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :380.462′-O-Methylcytidine
CAS :<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Formule :C10H15N3O5Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :257.24Palbociclib Isethionate
CAS :<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Formule :C24H29N7O2·C2H6O4SDegré de pureté :99.01% - 99.27%Couleur et forme :SolidMasse moléculaire :573.66Arginine-glycine-aspartic acid
CAS :<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34Natalizumab
CAS :<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Degré de pureté :98.00%Couleur et forme :LiquidMasse moléculaire :N/AFUBP1-IN-1
CAS :<p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>Formule :C19H14F3N3O2SDegré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :405.39BMS-265246
CAS :<p>BMS-265246 is a potent and selective CDK1/2 inhibitor.</p>Formule :C18H17F2N3O2Degré de pureté :99.25% - 99.57%Couleur et forme :SolidMasse moléculaire :345.34ML264
CAS :<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Formule :C17H21ClN2O4SDegré de pureté :99.33% - 99.45%Couleur et forme :SolidMasse moléculaire :384.88XMD8-92
CAS :<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formule :C26H30N6O3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :474.55Verosudil hydrochloride
CAS :<p>Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS & OHT/XFG, offering a new treatment option.</p>Formule :C17H18ClN3O2SCouleur et forme :SolidMasse moléculaire :363.86CCT241736
CAS :<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.81%Couleur et forme :SolidMasse moléculaire :456.37NY2267
CAS :<p>NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl</p>Formule :C38H43N3O6Degré de pureté :99.16% - 99.27%Couleur et forme :SolidMasse moléculaire :637.7610058-F4
CAS :<p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.</p>Formule :C12H11NOS2Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :249.35BTB-1
CAS :<p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>Formule :C12H8ClNO4SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :297.71Alisertib
CAS :<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Formule :C27H20ClFN4O4Degré de pureté :98.31% - >99.99%Couleur et forme :SolidMasse moléculaire :518.92SNS-314
CAS :<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formule :C18H15ClN6OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.93LDN-192960 hydrochloride
CAS :<p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>Formule :C18H22Cl2N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35Abemaciclib
CAS :<p>Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.</p>Formule :C27H32F2N8Degré de pureté :99.43% - 99.87%Couleur et forme :SolidMasse moléculaire :506.59Silver sulfadiazine
CAS :<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formule :C10H9AgN4O2SDegré de pureté :99.04% - 99.58%Couleur et forme :SolidMasse moléculaire :357.14Camostat mesylate
CAS :<p>Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.</p>Formule :C21H26N4O8SDegré de pureté :99.31% - 99.85%Couleur et forme :Crystalline SolidMasse moléculaire :494.52Tipiracil
CAS :<p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>Formule :C9H11ClN4O2Degré de pureté :99.815%Couleur et forme :SolidMasse moléculaire :242.66H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS :<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formule :C23H38N10O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :614.61Adefovir dipivoxil
CAS :<p>Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against</p>Formule :C20H32N5O8PDegré de pureté :98% - 99.80%Couleur et forme :It Has Broad-Spectrum Antiviral ActivityMasse moléculaire :501.47Ilorasertib
CAS :<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.545-Fluorocytidine
CAS :<p>5-Fluorocytidine with antiviral activity</p>Formule :C9H12FN3O5Degré de pureté :99.23%Couleur et forme :White PowderMasse moléculaire :261.21JNJ-7706621
CAS :<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36KW-2449
CAS :<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formule :C20H20N4ODegré de pureté :98.43% - 99.69%Couleur et forme :SolidMasse moléculaire :332.46-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS :<p>6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).</p>Formule :C8H7BrO3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :231.04Ara-G
CAS :<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Formule :C10H13N5O5Degré de pureté :98.74%Couleur et forme :Slightly Off White To White PowderMasse moléculaire :283.24Empesertib
CAS :<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Formule :C29H26FN5O4SDegré de pureté :97.45% - 99.4%Couleur et forme :SolidMasse moléculaire :559.61Longdaysin
CAS :<p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>Formule :C16H16F3N5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :335.33Danusertib
CAS :<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.55CCG-100602
CAS :<p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>Formule :C21H17ClF6N2O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :478.824μ8C
CAS :<p>4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.</p>Formule :C11H8O4Degré de pureté :97.48% - 98.45%Couleur et forme :SolidMasse moléculaire :204.18Didox
CAS :<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Formule :C7H7NO4Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :169.13T56-LIMKi
CAS :<p>T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.</p>Formule :C19H14F3N3O3Degré de pureté :98.39% - 99.57%Couleur et forme :SolidMasse moléculaire :389.33BAY-1816032
CAS :<p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>Formule :C27H24F2N6O4Degré de pureté :98.02% - 99.81%Couleur et forme :SolidMasse moléculaire :534.51Mycro 3
CAS :<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Formule :C24H17ClF2N6O4Degré de pureté :99.51% - 99.61%Couleur et forme :SolidMasse moléculaire :526.88ZCL278
CAS :<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Formule :C21H19BrClN5O4S2Degré de pureté :96.29% - 99.72%Couleur et forme :SolidMasse moléculaire :584.89BRD32048
CAS :<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Formule :C16H22N6ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :314.39Tirapazamine
CAS :<p>Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.</p>Formule :C7H6N4O2Degré de pureté :96.65% - 99.87%Couleur et forme :Orange-Red Crystalline PowderMasse moléculaire :178.15GAK inhibitor 49 hydrochloride
<p>Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.</p>Formule :C20H23ClN2O5Couleur et forme :SolidMasse moléculaire :406.86PfDHODH-IN-1
CAS :<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24TP-353
CAS :<p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>Formule :C35H30FNO3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :531.62ENMD-2076
CAS :<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47Isoindigotin
CAS :<p>Isoindigotin is used in the therapy of Y.</p>Formule :C16H10N2O2Degré de pureté :98.14% - ≥95%Couleur et forme :SolidMasse moléculaire :262.26Cyclo(RGDyK) trifluoroacetate
CAS :<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72IXA4
CAS :<p>IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.</p>Formule :C24H28N4O4Degré de pureté :99.8% - 99.85%Couleur et forme :SolidMasse moléculaire :436.5Alovudine
CAS :<p>3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.</p>Formule :C10H13FN2O4Degré de pureté :99.41%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :244.22STF-083010
CAS :<p>STF-083010 is a selective inhibitor of the IRE1α endonuclease.</p>Formule :C15H11NO3S2Degré de pureté :98.09% - 99.45%Couleur et forme :SolidMasse moléculaire :317.381,4-Anthraquinone
CAS :<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Formule :C14H8O2Degré de pureté :95.96% - 97.01%Couleur et forme :Orange Brown SolidMasse moléculaire :208.21BI-1347
CAS :<p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>Formule :C22H20N4ODegré de pureté :96.7% - 99.63%Couleur et forme :SolidMasse moléculaire :356.42COH29
CAS :<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formule :C22H16N2O5SDegré de pureté :97.04% - 98.92%Couleur et forme :SolidMasse moléculaire :420.44Pyridostatin Trihydrochloride
CAS :<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Formule :C31H35Cl3N8O5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :706.02Fialuridine
CAS :<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.88%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09Simeprevir sodium
CAS :<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Formule :C38H46N5NaO7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.92Dasabuvir
CAS :<p>Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.</p>Formule :C26H27N3O5SDegré de pureté :99.54% - 99.62%Couleur et forme :SolidMasse moléculaire :493.57EG1
CAS :<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Formule :C22H18N2O5Degré de pureté :97.48%Couleur et forme :SolidMasse moléculaire :390.39
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