Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(270 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(97 produits)
- Lipides(59 produits)
- Lipoxygénase(125 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(164 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8625 produits trouvés pour "Métabolisme"
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(S)-O-Desmethyl Venlafaxine N-Oxide
CAS :<p>(S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide metabolite of Venlafaxine, an SNRI antidepressant.</p>Formule :C16H25NO3Couleur et forme :SolidMasse moléculaire :279.37ecMetAP-IN-1
CAS :<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Formule :C13H11N3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :209.25MS-PPOH
CAS :<p>MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectively</p>Formule :C16H21NO4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :323.41Ferulic acid acyl-β-D-glucoside
CAS :<p>Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1).</p>Formule :C16H20O9Couleur et forme :SolidMasse moléculaire :356.327Glutamate dehydrogenase (NAD(P))
CAS :<p>GLDH, found in liver/kidney/brain/muscle/intestine, catalyzes glutamate to α-KG in urea cycle.</p>Couleur et forme :SolidBoc-L-aspartic acid 4-benzyl ester
CAS :<p>Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.</p>Formule :C16H21NO6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.34Endoglycoceramidase I (EGCase I)
CAS :<p>EGCase I is a glycosidase used in biochemistry to transfer GSL sugars to 1-alkanols' primary hydroxyl groups.</p>Couleur et forme :SolidGlisoprenin D
CAS :<p>Glisoprenin D is a useful organic compound for research related to life sciences. The catalog number is T125390 and the CAS number is 205594-89-4.</p>Formule :C45H84O7Couleur et forme :SolidMasse moléculaire :737.16ML266
CAS :<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Formule :C24H22BrN3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :496.355,6-Dihydro-2H-pyran-2-one
CAS :<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1Fexarene
CAS :<p>Fexarene is a non-steroidal FXR agonist.</p>Formule :C32H33NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.62Glycodeoxycholic acid monohydrate
CAS :<p>Glycodeoxycholic acid monohydrate is a nuclear receptor ligand.</p>Formule :C26H45NO6Couleur et forme :SolidMasse moléculaire :467.64COMT-IN-2
<p>COMT-IN-2 (compound 9) is the most potent inhibitor of COMT, exhibiting selective inhibition for brain (IC50=24 nM) and liver (IC50=81 nM) MB-COMT compared to the liver S-COMT isoform (IC50=620 nM).</p>Couleur et forme :Odour SolidOrotidine
CAS :<p>Orotidine (Uridin-6-carboxylic acid) is a nucleoside found in bacteria, fungi, and plants. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid).</p>Formule :C10H12N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.21Penicitide A
CAS :<p>Penicitide A: marine metabolite, moderately cytotoxic to A. brassicae, HepG2 cells.</p>Formule :C18H34O4Couleur et forme :SolidMasse moléculaire :314.46MCC-555
CAS :<p>MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.</p>Formule :C21H16FNO3SDegré de pureté :99.07% - 99.82%Couleur et forme :SolidMasse moléculaire :381.42Daprodustat
CAS :<p>Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.</p>Formule :C19H27N3O6Degré de pureté :97% - 99.82%Couleur et forme :SolidMasse moléculaire :393.43HIF1-IN-3
CAS :<p>HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in</p>Formule :C26H24N2O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :412.48GGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.134172-Methyl-1-naphthol
CAS :<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formule :C11H10ODegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :158.2Bazinaprine
CAS :<p>Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression.</p>Formule :C17H19N5ODegré de pureté :99.65% - 99.93%Couleur et forme :SolidMasse moléculaire :309.37Yokonoside
CAS :<p>Yokonoside is a biochemical.</p>Formule :C20H21NO11Couleur et forme :SolidMasse moléculaire :451.384DSPE-PEG1000-CSTSMLKAC
<p>DSPE-PEG1000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. The CSTSMLKAC component facilitates phage-mediated targeting to ischemic cardiac tissue. DSPE-PEG1000-CSTSMLKAC is applicable in drug delivery.</p>Couleur et forme :Odour SolidMorin 3-O-β-D-glucopyranoside
CAS :<p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>Formule :C21H20O12Couleur et forme :SolidMasse moléculaire :464.38(24S)-24,25-Dihydroxyvitamin D3
CAS :<p>(24S)-24,25-Dihydroxyvitamin D3 undergoes various levels of hydroxylation to form active vitamin D3 analogs.</p>Formule :C27H44O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :416.64ACAT-IN-4 hydrochloride
CAS :<p>ACAT-IN-4 hydrochloride is a potent ACAT inhibitor and blocks NF-κB transcription.</p>Formule :C32H51ClN2O5SCouleur et forme :SolidMasse moléculaire :611.28Arachidonoyl-L-carnitine chloride
CAS :<p>Arachidonoyl-L-carnitine chloride is an endogenous metabolite and acylcarnitine widely used in biochemical experiments and studies of metabolic disorders.</p>Formule :C27H46ClNO4Couleur et forme :SolidMasse moléculaire :484.11Ftase inhibitor III
CAS :<p>Ftase Inhibitor III, derived from a phenotypic screen, functions as an anion-dependent inhibitor of Farnesyltransferase.</p>Formule :C24H34N6OCouleur et forme :SolidMasse moléculaire :422.577L-Aspartic acid (Standard)
CAS :<p>L-Aspartic acid (Standard) is a standard material used in the analysis of L-Aspartic acid, commonly referenced in its research and analysis.</p>Formule :C4H7NO4Degré de pureté :99.79%Couleur et forme :White SolidMasse moléculaire :133.1Evinacumab
CAS :<p>Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.</p>Degré de pureté :100% (SEC-HPLC) - 99.43% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaPhenolic acid
CAS :<p>Phenolic acid is an endogenous metabolite.</p>Formule :C7H8D2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :144.16Fmoc-Asp-OAll
CAS :<p>Fmoc-Asp-OAll (Fmoc-L-aspartic acid a-allyl ester) is an aspartic acid derivative.</p>Formule :C22H21NO6Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :395.41Isbufylline
CAS :<p>Isbufylline can exert significant anti-inflammatory actions, in addition to its bronchodilator activity.</p>Formule :C11H16N4O2Degré de pureté :90% - 97.59%Couleur et forme :SolidMasse moléculaire :236.27Leucomyosuppressin
CAS :<p>Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.</p>Formule :C59H84N16O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1257.4181,1,3-Tribromoacetone
CAS :<p>1,1,3-Tribromoacetone (1,1,3-tribromo-2-propanone) is an impurity of methotrexate.</p>Formule :C3H3Br3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.773-Hydroxysebacic acid
CAS :<p>3-Hydroxysebacic acid, an endogenous metabolite found in urine, is utilized in the study of Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) [1] [2].</p>Formule :C10H18O5Couleur et forme :SolidMasse moléculaire :218.25(±)9-HODE cholesteryl ester
CAS :<p>(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Formule :C45H76O3Couleur et forme :SolidMasse moléculaire :665.19(R)-HODE cholesteryl ester
CAS :<p>9(R)-HODE cholesteryl ester, from atherosclerotic lesions, may form enzymatically or by lipid peroxidation; used as a chiral analysis standard.</p>Formule :C45H76O3Couleur et forme :SolidMasse moléculaire :665.1Ninerafaxstat
CAS :<p>Ninerafaxstat shifts metabolism to glucose, boosts mitochondrial function, and inhibits cancer growth.</p>Formule :C22H29N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.48PROTAC IDO1 Degrader-1
CAS :<p>First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 μM), boosts H ER2 CAR-T cell efficacy.</p>Formule :C40H53BrFN9O13Couleur et forme :SolidMasse moléculaire :966.816AP219
CAS :<p>AP39 boosts mitochondrial H2S with triphenylphosphonium and dithiolethione; AP219 lacks H2S-donating part.</p>Formule :C28H34O2PCouleur et forme :SolidMasse moléculaire :433.551Probestin
CAS :<p>Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.</p>Formule :C26H38N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.60OH-Chol
CAS :<p>OH-Chol is a cationic cholesterol used for siRNA delivery and gene silencing in cells and mice, often in lipoplexes or nanoparticles.</p>Formule :C32H56N2O2Couleur et forme :SolidMasse moléculaire :500.812ALT-100 (Human IgG1)
<p>ALT-100 (HumanIgG1) is a human-derived IgG1 monoclonal antibody that targets NAMPT. For its isotype control, please refer to HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour LiquidPDE2A-IN-1
CAS :<p>PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM.</p>Formule :C23H22F2N6Couleur et forme :SolidMasse moléculaire :420.468RMC-3943
CAS :<p>RMC-3943 is a potent SHP2 allosteric inhibitor with an IC50 of 2.19 nM.</p>Formule :C18H22Cl2N6SCouleur et forme :SolidMasse moléculaire :425.38IGUANA-1 free base
CAS :<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Formule :C26H24ClN3O2Couleur et forme :SolidMasse moléculaire :445.94Campestanol
CAS :<p>Campestanol is a natural plant sterol from Brassica campestris.</p>Formule :C28H50OCouleur et forme :SolidMasse moléculaire :402.711-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
CAS :<p>1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol is an intrinsic metabolite and a component of the cell membrane [1].</p>Formule :C47H83O13PCouleur et forme :SolidMasse moléculaire :887.13Lipstatin
CAS :<p>Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.</p>Formule :C29H49NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.7α-1,3-Galactosyltransferase (a1,3GalT)
CAS :<p>a1,3GalT (GGTA1) synthesizes α-gal glycan by adding galactose from UDP to glycoproteins.</p>Couleur et forme :SolidOH-C-Chol
CAS :<p>OH-C-Chol, a cationic cholesterol derivative, used in siRNA delivery and gene silencing in cells and mice.</p>Formule :C32H56N2O3Couleur et forme :SolidMasse moléculaire :516.811Impurity C of Alfacalcidol
CAS :<p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Formule :C35H49N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.78PKM2 activator 6
<p>Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM,</p>Couleur et forme :Odour SolidRetinyl glucoside
CAS :<p>Retinyl-β-D-glucoside, a biologically active metabolite of vitamin A, naturally occurs in fish and mammals.</p>Formule :C26H40O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.59Ganglioside sialidase (AuSialidase S)
CAS :<p>AuSialidase S is an endogenous metabolite involved in neuronal differentiation and neurite outgrowth.</p>Couleur et forme :Solid1,4-Dihydropyridine
<p>1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.</p>Formule :C12H17NO4Couleur et forme :SolidMasse moléculaire :239.271-Palmitoyl-2-linoleoyl PE
CAS :<p>Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.</p>Formule :C39H74NO8PCouleur et forme :SolidMasse moléculaire :715.994Diphlorethohydroxycarmalol
CAS :<p>Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.</p>Formule :C24H16O13Couleur et forme :SolidMasse moléculaire :512.379Ionizable Lipid 4
CAS :<p>Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.</p>Formule :C48H85NO7Couleur et forme :SolidMasse moléculaire :788.19HPA-IN-1
<p>HPA-IN-1: potent human pancreatic α-amylase inhibitor; IC50: 12.0 μM for HPA, 410.4 μM for α-glucosidase.</p>Formule :C33H32N4O11Couleur et forme :SolidMasse moléculaire :660.631-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine
CAS :<p>Endogenous metabolite in urine, 1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine, linked to obesity research.</p>Formule :C46H82NO7PCouleur et forme :SolidMasse moléculaire :792.12Omfiloctocog alfa
CAS :<p>Omfiloctocog alfa (SCT-800) is a recombinant FVIII for Hemophilia A research.</p>Couleur et forme :LiquidAlitame hydrate
CAS :<p>Alitame hydrate is a non-nutritive sweetener that is 2000 times sweeter than sucrose. It is formed from aspartic acid, alanine &amp; an amide.</p>Formule :C14H25N3O4SH2OCouleur et forme :SolidMasse moléculaire :376.47Paraherquamide E
CAS :<p>Fungal-derived paraherquamide E kills C. elegans and O. fasciatus, reduces T. colubriformis eggs in gerbils.</p>Formule :C28H35N3O4Couleur et forme :SolidMasse moléculaire :477.605VU533
CAS :<p>VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.</p>Formule :C21H22FN3O3S2Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :447.55MPC-IN-1
<p>MPC-IN-1 (compound 4i), a derivative of UK-5099, is a cyanocinnamate-based inhibitor of the mitochondrial pyruvate transporter (MPC). This compound selectively fosters the development of hair follicle stem cells while not impacting normal cells. It enhances cellular lactate production and has shown significant hair growth promotion in mice, suggesting its potential use in combating hair loss.</p>Formule :C18H13N3O2Couleur et forme :SolidMasse moléculaire :303.31LKY-047
CAS :<p>LKY-047 is a Decursin derivative, selectively inhibits CYP2J2 with IC50 of 1.7 μM, not affecting other human P450s.</p>Formule :C23H19NO7Couleur et forme :SolidMasse moléculaire :421.405Enpp-1-IN-14
CAS :<p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>Formule :C15H22ClN5O4SDegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :403.88UK 227786
CAS :<p>UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.</p>Formule :C22H22Cl2N4O4Degré de pureté :99.9%Couleur et forme :SoildMasse moléculaire :477.34N-Desethyl Bimatoprost
CAS :<p>N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide.</p>Formule :C23H33NO4Couleur et forme :SolidMasse moléculaire :387.51Carboxyaminoimidazole ribotide
CAS :<p>CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.</p>Formule :C9H14N3O9PCouleur et forme :SolidMasse moléculaire :339.21-Palmitoyl Lysophosphatidic Acid
CAS :<p>1-Palmitoyl Lysophosphatidic Acid boosts antibiotics against P. aeruginosa by binding Ca2+ and Mg2+.</p>Formule :C19H39O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.48(R)-AS-1
CAS :<p>(R)-AS-1 is a selective positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2), with an EC50 of 11 nM. At doses of 60 and 90 mg/kg, (R)-AS-1 enhances spontaneous locomotor activity in mice. It demonstrates anticonvulsant properties in mouse seizure models induced by maximal electroshock (MES), pentylenetetrazole (PTZ), or electric current stimulation (32 or 44 mA), with ED50 values of 66.3, 36.3, 15.6, and 41.6 mg/kg, respectively. This compound is applicable in neurological disease research.</p>Formule :C14H16N2O3Couleur et forme :SolidMasse moléculaire :260.29D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)
<p>D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP), belonging to the CAZy glycoside hydrolase family GH112, plays a pivotal role in</p>Couleur et forme :SolidO-Desisobutyl-O-n-propyl Febuxostat
CAS :<p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>Formule :C15H14N2O3SCouleur et forme :SolidMasse moléculaire :302.35Tetracosanoyl-sulfatide
CAS :<p>C24 3'-sulfo Galactosylceramide is a key myelin sulfatide, high in leukodystrophy patients, non-immunogenic compared to C24:1 variant.</p>Formule :C48H93NO11SCouleur et forme :SolidMasse moléculaire :892.32N1,N12-Diacetylspermine dihydrochloride
CAS :<p>Diacetylspermine 2HCl, a diacetylated Spermine, is a cancer biomarker linked to the disease's up-regulation.</p>Formule :C14H32Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.342-(2',3',4'-Trihydroxybutyl)quinoxaline
CAS :<p>2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite.</p>Formule :C12H14N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.25ARC19499
CAS :<p>ARC19499, an aptamer, inhibits TFPI to aid clotting through the extrinsic pathway, enhancing thrombin in hemophilia.</p>Couleur et forme :Solid1,2,3,6,7,8-Hexachlorodibenzofuran
CAS :<p>1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.</p>Formule :C12H2Cl6OCouleur et forme :SolidMasse moléculaire :374.86Reduced Haloperidol
CAS :<p>Reduced haloperidol, an active metabolite of haloperidol, binds dopamine D2/sigma-1 receptors and inhibits neurotransmitter reuptake.</p>Formule :C21H25ClFNO2Couleur et forme :SolidMasse moléculaire :377.88N-Lactoyl-Phenylalanine
CAS :<p>N-Lactoyl-Phenylalanine (Lac-Phe) is a peptide coupling of lactic acid and phenylalanine that can be used in the study of obesity and metabolic off diseases.</p>Formule :C12H15NO4Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :237.25α-Hydroxyglutaric Acid Lithium
<p>α-Hydroxyglutaric Acid Lithium is an α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase inhibitor of ATP synthase.</p>Formule :C5H6Li2O5Degré de pureté :≥98%Couleur et forme :SoildMasse moléculaire :159.98Mavodelpar free acid hydrochloride
<p>Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.</p>Formule :C31H31ClFNO5Degré de pureté :98.13%Couleur et forme :SoildMasse moléculaire :552.03Amastatin hydrochloride
CAS :<p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>Formule :C21H39ClN4O8Couleur et forme :White To Off-White PowderMasse moléculaire :511.01Benzo[b]furan-2-carboxaldehyde
CAS :<p>Benzo[b]furan-2-carboxaldehyde is a CYP2A6 inhibitor and can be used in biochemical experiments and drug synthesis.</p>Formule :C9H6O2Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :146.14Imidazole-d4
CAS :<p>Imidazole-d4 is an isotope-labeled variant of imidazole, which is a heterocyclic aromatic compound. Imidazole molecules serve as inhibitors for acetylcholinesterase (AChEI) and xanthine oxidase (XO) and have been utilized as corrosion inhibitors. They display a range of biological activities, including antifungal, antitubercular, anti-inflammatory, antioxidant, and analgesic properties. Imidazole inhibits platelet microsomes from converting endoperoxides (PGG2 and PGH2) into thromboxane A2. Additionally, imidazole derivatives show inhibitory effects on the SARS-CoV-2 3CLpro enzyme, offering potential for research in Alzheimer’s disease, gout, COVID-19, and thrombotic disorders.</p>Formule :C3H4N2Couleur et forme :SolidMasse moléculaire :72.1Glycogen phosphorylase-IN-2
<p>Glycogen phosphorylase-IN-2 (compound 9C) is an inhibitor of glycogen phosphorylase, with a Ki value of 1.9 nM and an IC50 value of 4 nM.</p>Couleur et forme :Odour SolidNap-FF
CAS :<p>Nap-FF is a cell-penetrating dipeptide used in the preparation of hydrogel chemical sensors and for research in targeted drug delivery.</p>Formule :C30H28N2O4Couleur et forme :SolidMasse moléculaire :480.554TMP-778
CAS :<p>TMP-778 is a selective inverse agonist of RORγt.</p>Formule :C31H30N2O4Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :494.58Flumethasone 21-acetate
CAS :<p>Flumethasone 21-acetate is an anti-inflammatory corticosteroid.</p>Formule :C24H30F2O6Couleur et forme :SolidMasse moléculaire :452.49O-Demethyl Lenvatinib
CAS :<p>O-Demethyl Lenvatinib, a Lenvatinib metabolite, is an oral TKI targeting VEGFR, FGFR, PDGFR, KIT & RET with potent antitumor effects.</p>Formule :C20H17ClN4O4Couleur et forme :SolidMasse moléculaire :412.83Previtamin D3
CAS :<p>Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).</p>Formule :C27H44OCouleur et forme :SolidMasse moléculaire :384.648Prolylglutamic acid
CAS :<p>Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.</p>Formule :C10H16N2O5Couleur et forme :SolidMasse moléculaire :244.246α-hydroxy Paclitaxel
CAS :<p>6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.</p>Formule :C47H51NO15Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :869.91D-Lactate dehydrogenase
CAS :<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Couleur et forme :SolidhCAXII-IN-7
<p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>Formule :C26H25N5O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.64Betulin ditosylate
CAS :<p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>Formule :C44H62O6S2Couleur et forme :SolidMasse moléculaire :751.09Reticulol
CAS :<p>Reticulol is an isocoumarin derivative produced by certain species of Streptomyces.</p>Formule :C11H10O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :222.191-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS :<p>1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.</p>Formule :C12H14N2O4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :250.25Cyano-myracrylamide
CAS :<p>Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with an IC50 value of 1.35 µM. It also inhibits the S-palmitoylation of EGFR and CD36. In HEK293T cells expressing recombinant E. coli GobX, recombinant human MyD88, or endogenous Ras, Cyano-myracrylamide inhibits the S-palmitoylation of E. coli E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6.</p>Formule :C19H34N2OCouleur et forme :SolidMasse moléculaire :306.49DPPD-Q
CAS :<p>DPPD-Q, an antioxidant and an oxidative derivative of substituted p-phenylenediamine (DPPD), is identified in tire wear particles, rubber debris, particulate matter 2.5 (PM2.5), and wastewater influents and effluents. At a concentration of 5 µM, DPPD-Q inhibits soybean urease by 91.4%.</p>Formule :C18H14N2O2Couleur et forme :SolidMasse moléculaire :290.32DSPE-PEG5000-RVG29
<p>DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.</p>Couleur et forme :Odour SolidPyruvate kinase
CAS :<p>Pyruvate kinase is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP [1] .</p>Couleur et forme :Solid5-(3-Hydroxyphenyl)-5-phenylhydantoin
CAS :<p>5-(3-Hydroxyphenyl)-5-phenylhydantoin is a bioactive chemical.</p>Formule :C15H12N2O3Couleur et forme :SolidMasse moléculaire :268.27D,L-erythro-PDMP
CAS :<p>D,L-erythro-PDMP inhibits growth in rabbit fibroblasts and blocks UDP-glucose: ceramide glucosyltransferase.</p>Formule :C23H38N2O3Couleur et forme :SolidMasse moléculaire :390.568APP-018
CAS :<p>APP-018 (D-4F) is an 18 D-amino acid peptide that mimics apolipoprotein A-I (apoA-I). It enhances the anti-inflammatory properties of high-density lipoprotein (HDL) and is applicable in cardiovascular disease research.</p>Formule :C114H156N24O28Couleur et forme :SolidMasse moléculaire :2310.6UG-480
<p>UG-480 is a Gemini analog that effectively stabilizes the active VDR conformation. It exhibits antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells and is utilized in cancer research.</p>Couleur et forme :Odour SolidN-Stearoylsphingomyelin
CAS :<p>N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin), a sphingolipid, inhibits Phospholipase Cδ1 (PLCδ1) [1].</p>Formule :C41H83N2O6PCouleur et forme :SolidMasse moléculaire :731.08Toddacoumalone
CAS :<p>Toddacoumalone, a natural PDE4 inhibitor, shows promise for inflammatory disease research.</p>Formule :C31H31NO6Couleur et forme :SolidMasse moléculaire :513.58Phosphodiesterase II
CAS :<p>Phosphodiesterase II (PDE2) breaks down cAMP and cGMP, important in cellular regulation and widespread in tissues for biochemical research.</p>Couleur et forme :SolidZG-2033
CAS :<p>ZG-2033 (Compound 26) is an orally active HIF-2α agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.</p>Formule :C15H14N2O2SCouleur et forme :SolidMasse moléculaire :286.35YYLLVR
CAS :<p>YYLLVR is an inhibitory peptide of angiotensin-converting enzyme (ACE) with an inhibition rate of 89.10%. It demonstrates a low binding energy to ACE at -35.98 kcal/mol. YYLLVR can be utilized in hypertension research.</p>Formule :C41H63N9O9Couleur et forme :SolidMasse moléculaire :825.99α-Glucosidase-IN-77
<p>α-Glucosidase-IN-77 (Compound H7) is a non-competitive α-glucosidase inhibitor with an IC50 of 1.25 μM. It reduces blood glucose levels, improves glucose tolerance, regulates gut microbiota, and exhibits hepatoprotective effects in a mouse model of type 2 diabetes.</p>Formule :C25H16F3NO5SCouleur et forme :SolidMasse moléculaire :499.46MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formule :C24H21NO6Couleur et forme :SolidMasse moléculaire :419.4313-cis-Vitamin A palmitate
CAS :<p>13-cis-Retinyl palmitate in corn flakes is 75% as active as all-trans form.</p>Formule :C36H60O2Couleur et forme :SolidMasse moléculaire :524.86Abz-Ser-Pro-3-nitro-Tyr
CAS :<p>Abz-Ser-Pro-3-nitro-Tyr is the substrate of ACE2 (angiotensin-converting enzyme-2) [1] .</p>Formule :C24H27N5O9Couleur et forme :SolidMasse moléculaire :529.52,7"-Phloroglucinol-6,6'-bieckol
CAS :<p>2,7"-Phloroglucinol-6,6'-bieckol serves as an effective oral dual α-amylase/α-glucosidase inhibitor, demonstrating IC 50 concentrations of 6.94 μM and 23.35 μM, respectively. This compound is beneficial in mitigating postprandial hyperglycemia among diabetic mice and is applicable in diabetes research [1].</p>Formule :C48H30O23Couleur et forme :SolidMasse moléculaire :974.74LYP-IN-3
<p>LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway</p>Formule :C35H27NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :589.662-Nitrophenyl a-D-glucopyranoside
CAS :<p>2-Nitrophenyl a-D-glucopyranoside is a substrate of β-glucosidase [1] .</p>Formule :C12H15NO8Couleur et forme :SolidMasse moléculaire :301.25Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
CAS :<p>Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (pNP-G7) is a substrate for α-amylase, used to measure α-amylase activity.</p>Formule :C50H77NO38Couleur et forme :SolidMasse moléculaire :1300.132',5,6',7-Tetrahydroxyflavone
CAS :<p>2',5,6',7-Tetrahydroxyflavone is a useful organic compound for research related to life sciences.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.239IPH5201
<p>IPH5201 is a human IgG1 monoclonal antibody (mAb) targeting ENTPD1/CD39. It enhances the accumulation of immunostimulatory ATP released by tumor cells undergoing combination chemotherapy (CT) and reduces the levels of immunosuppressive adenosine (Ado) in the tumor microenvironment (TME). IPH5201 is useful for research on antitumor immunity. Recommended isotype control: Human IgG1 kappa, Isotype Control.</p>Couleur et forme :Odour LiquidAndrastin A
CAS :<p>Andrastin A is a useful organic compound for research related to life sciences. The catalog number is T125574 and the CAS number is 174232-42-9.</p>Formule :C28H38O7Couleur et forme :SolidMasse moléculaire :486.605AUPF02
CAS :<p>AUPF02, a 5-aryluracil derivative, is an effective anti-breast cancer compound with an IC50 value of 23.4 µM against MCF-7 cells.</p>Formule :C14H9F5N2OCouleur et forme :SolidMasse moléculaire :316.23Human Endogenous Metabolite Compound Library Plus
<p>A unique collection of xnum endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.</p>Couleur et forme :Odour Solidα-Glucosidase-IN-39
<p>α-Glucosidase-IN-39 is a potent α-glucosidase enzyme inhibitor, exhibiting an IC50 value of 869.06 ppm. It is applicable for use in antidiabetic studies [1].</p>Degré de pureté :98%Couleur et forme :Odour SolidNucleoside hydrolase (IAGNH)
CAS :<p>IAGNH, a glycosidase, breaks N-glycosidic bonds in nucleosides, recycling nucleobases and ribose.</p>Couleur et forme :SolidAlfacalcidol-D6
CAS :<p>Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Formule :C27H44O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.67EDDA
CAS :<p>Ethylenediaminediacetic acid is derived from two molecules of glycine linked by amines.</p>Formule :C6H12N2O4Couleur et forme :SolidMasse moléculaire :176.17(1S)-Calcitriol
CAS :<p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>Formule :C27H44O3Couleur et forme :SolidMasse moléculaire :416.6463,5,6,7,8,4′-hexamethoxyflavone
CAS :<p>3,5,6,7,8,4′-hexamethoxyflavone is a natural product for research related to life sciences. The catalog number is TN7114 and the CAS number is 34170-18-8.</p>Formule :C21H22O8Couleur et forme :SolidMasse moléculaire :402.399Neogen
CAS :<p>Neogen, also known as Jadinol PU, is a drug potentially for the restoration of the immune system and hemopoiesis after cytostatics treatment.</p>Formule :C22H30N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :446.50N6-Isopentenyladenosine
CAS :<p>N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.</p>Formule :C15H21N5O4Degré de pureté :97.13% - 99.69%Couleur et forme :SolidMasse moléculaire :335.36ZLY28
<p>ZLY28 is a novel, first-in-class compound with specific intestinal restriction and oral activity, serving as a dual modulator of FXR and FABP1.</p>Formule :C29H23Cl2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.4Netupitant metabolite Netupitant N-oxide
CAS :<p>Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.</p>Formule :C30H32F6N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.59DSPE-PEG2000-GRGDS
<p>DSPE-PEG2000-GRGDS is a PEG-based compound formed from DSPE and the anti-adhesion peptide (GRGDS). GRGDS serves to inhibit the binding and adhesion between the extracellular matrix and cell surface integrins. This compound is applicable in drug delivery.</p>Couleur et forme :Odour Solidα-Amylase/α-Glucosidase-IN-3
<p>α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM</p>Formule :C23H14Cl4N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.27RMC-4630
CAS :<p>RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.</p>Formule :C20H27ClN6O2SDegré de pureté :99.07% - 99.65%Couleur et forme :SolidMasse moléculaire :450.99IR-117-17
CAS :<p>IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.</p>Formule :C59H110N2O5Couleur et forme :SolidMasse moléculaire :927.52Isocrenatoside
CAS :<p>Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting</p>Formule :C29H34O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.57Complement factor I
CAS :<p>Complement factor I, a serine protease, attenuates complement activity both in the fluid phase and on cell surfaces, working alongside cofactors such as factor</p>Degré de pureté :98%Couleur et forme :SolidROS-IN-2
<p>ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage</p>Formule :C42H62ClNO8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :776.46Bicyclic UK18
CAS :<p>Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.</p>Formule :C77H118N26O25S3Couleur et forme :SolidMasse moléculaire :1904.11hCAI/II/IV-IN-28
CAS :<p>hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.</p>Formule :C14H15N3O3SDegré de pureté :96.48%Couleur et forme :SolidMasse moléculaire :305.35SF2312 ammonium
<p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>Formule :C4H11N2O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :214.119-cis-Vitamin A palmitate
CAS :<p>9-cis-Vitamin A palmitate, a 9-cis isomer in corn flakes, has 26% activity of all-trans-vitamin A, the most active form.</p>Formule :C36H60O2Couleur et forme :SolidMasse moléculaire :524.874Triethyl phosphate
CAS :<p>Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".</p>Formule :C6H15O4PDegré de pureté :98%Couleur et forme :Clear LiquidMasse moléculaire :182.16ω-Hexatoxin-Hv1a
CAS :<p>ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].</p>Formule :C162H247N49O61S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4049.38ω-Tbo-IT1
<p>ω-Tbo-IT1, a peptide toxin extracted from the venom of Tibellus oblongus, functions as an inhibitor of insect calcium channels [1].</p>Formule :C171H285N61O53S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4332.05α-Glucosidase-IN-34
<p>α-Glucosidase-IN-34 (compound 7f) is a potent inhibitor of α-glucosidase, exhibiting an IC50 of 2.90 μM, and is applicable in research related to type 2</p>Formule :C28H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.47Febuxostat impurity 7
CAS :<p>Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Formule :C16H18N2O4SCouleur et forme :SolidMasse moléculaire :334.39Mannose 6 phosphate
CAS :Mannose 6-phosphate (M6P) features a type I integral membrane receptor.Formule :C6H13O9PMasse moléculaire :260.14α-Glucosidase-IN-27
<p>α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1</p>Formule :C22H20N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.48Pancreatic lipase-IN-2
Pancreatic lipase-IN-2 (compound 7r) is a potent inhibitor of pancreatic lipase (PL), with an IC50 value of 2.67 μM, and exhibits anti-obesity effects.Formule :C32H33N3O2SMasse moléculaire :523.22935Leucylproline
CAS :<p>Leucylproline is a peptide that proteolytic breakdown product by larger proteins.</p>Formule :C11H20N2O3Couleur et forme :SolidMasse moléculaire :228.29TMC-205
CAS :<p>TMC-205: natural antiproliferative fungal metabolite; boosts SV40 promoter transcription.</p>Formule :C14H13NO2Couleur et forme :SolidMasse moléculaire :227.26Cerebroside C
CAS :<p>Cerebroside C, a fungal glycosphingolipid from M. grisea, stimulates phytoalexin in rice and enhances wheat germination and growth at 4°C.</p>Formule :C43H79NO9Couleur et forme :SolidMasse moléculaire :754.09Epothilone C
CAS :<p>Epothilone C is a polyketide natural product. It is produced through the collaborative action of a nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) molecules within a multi-enzyme system. Epothilone C is utilized in tumor research.</p>Formule :C26H39NO5SCouleur et forme :SolidMasse moléculaire :477.657SHO1122147
<p>SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 μM). It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH).</p>Formule :C17H11ClN4O2Couleur et forme :SolidMasse moléculaire :338.748Phenylsulfamide
CAS :<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2(S,S)-GSK321
CAS :<p>(S,S)-GSK321 is a (S,S)-enantiomer of GSK321 [1] .</p>Formule :C28H28FN5O3Couleur et forme :SolidMasse moléculaire :501.55PBI-6DNJ
<p>PBI-6DNJ, an oral multivalent glycosidase inhibitor, has a K i of 0.14 μM against mouse α-glucosidase and aids type 2 diabetes research.</p>Formule :C120H146N26O36Couleur et forme :SolidMasse moléculaire :2528.6Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Formule :C13H16FeN2O2Couleur et forme :SolidMasse moléculaire :288.12α-Amylase/α-Glucosidase-IN-17
<p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>Formule :C19H18FNOCouleur et forme :SolidMasse moléculaire :295.35BChE-IN-36
<p>hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.</p>Couleur et forme :Odour SolidZG-2305
<p>ZG-2305 is an effective, selective, and orally active inhibitor of FIH (factor inhibiting hypoxia-inducible factor (FIH)), with Ki values of 79.6 nM for FIH and 2786 nM for PHD2. This compound enhances the expression of the EGLN3 gene, reduces cellular triglyceride levels, and decreases lipid accumulation. ZG-2305 holds potential for research into obesity and fatty liver disease.</p>Formule :C17H11Cl2N3O5Couleur et forme :SolidMasse moléculaire :408.19(±)10(11)-EpDPA
CAS :<p>Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.4951-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
CAS :<p>1-Arachidonoyl LPA: phospholipid with arachidonic acid, sn-1, LPA2 receptor binder, EC50 ~10 nM, modulates cytokine secretion, affects cell differentiation.</p>Formule :C23H42NO7PCouleur et forme :SolidMasse moléculaire :475.563α-1,4-Galactosyltransferase (LgtC)
CAS :<p>A4GALT (LgtC) adds galactose to lactosylceramide, forming globotriaosylceramide; used in P1 antigen synthesis.</p>Couleur et forme :Solid(S)-3,4-Dihydroxybutyric acid lithium hydrate
<p>(S)-3,4-Dihydroxybutyric acid (Li hydrate) is a urinary metabolite; higher in SSADH deficiency cases.</p>Formule :C4H9LiO5Couleur et forme :SolidMasse moléculaire :144.05NADP+ (sodium salt hydrate)
CAS :<p>NADP+ is the oxidized cofactor form of NADPH, vital for cell survival, redox balance, and signaling; synthesized from NAD+ and ATP.</p>Formule :C21H30N7NaO18P3Couleur et forme :SolidMasse moléculaire :784.413DSPE-PEG2000-R9
<p>DSPE-PEG2000-R9 is a PEG compound composed of DSPE and polyarginine-9 peptide (R9) peptide. It can be used for drug delivery.</p>Couleur et forme :Odour SolidM145724
CAS :M145724 ((3Z,6E)-1-N-Methylalbonoursin) is a metabolite that can be extracted from Streptomyces albus.Formule :C16H18N2O2Masse moléculaire :270.33PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.33ω-Conotoxin Bu8
<p>ω-Conotoxin Bu8 is a 25-amino-acid-residue ω-conotoxin that features three disulfide bridges.</p>Formule :C103H174N42O35S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2753.13hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Couleur et forme :Odour SolidDSPE-PEG2000-M2pep
<p>DSPE-PEG2000-M2pep is a PEG compound formed from DSPE and the M2-polarized macrophage-targeting peptide (M2pep). M2pep acts as a monovalent or multivalent ligand conjugated with pro-apoptotic peptides to specifically target M2 macrophages with toxic effects. DSPE-PEG2000-M2pep is applicable for drug delivery.</p>Couleur et forme :Odour SolidAngiotensinogen (1-14), human TFA
<p>Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is a precursor for all angiotensin peptides.</p>Formule :C85H123N24F3O21Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1874.06IDO1/TDO-IN-7
<p>IDO1/TDO-IN-7 (Compound 43b), an isochinoline derivative, functions as a potent dual inhibitor of IDO1/TDO with IC50 values of 0.31 μM and 0.08 μM, respectively. Demonstrating favorable pharmacokinetics and strong antitumor efficacy in the B16-F10 tumor model, this compound also exhibits low toxicity.</p>Couleur et forme :Odour SolidACAT-IN-3
CAS :<p>ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.</p>Formule :C25H36N2O6SCouleur et forme :SolidMasse moléculaire :492.63DSPE-PEG5000-PP1
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the PP1 peptide, which targets inflammatory atherosclerotic plaques. It can be used for drug delivery.</p>Couleur et forme :Odour SolidCalcitriol Derivatives
<p>Calcitriol Derivatives is an analog of vitamin D3.</p>Formule :C30H47NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.7DSPE-PEG2000-VIP
<p>DSPE-PEG2000-VIP is a PEG-based compound composed of DSPE and the vasoactive intestinal peptide (VIP). This compound is useful for drug delivery applications.</p>Couleur et forme :Odour Solid19,20-Epoxycytochalasin D
CAS :<p>Fungal metabolite 19,20-Epoxycytochalasin D from Nemania sp. kills P. falciparum; non-toxic to Vero, toxic to BT-549, LLC-PK11, P388 cells.</p>Formule :C30H37NO7Couleur et forme :SolidMasse moléculaire :523.626NU223612
CAS :<p>"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."</p>Formule :C49H55FN6O9Couleur et forme :SolidMasse moléculaire :890.99hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5RPR132595A hydrochloride
<p>RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via</p>Formule :C28H31ClN4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.02AChE/BChE-IN-17
<p>AChE/BChE-IN-17 (compound 8m) is a potent inhibitor of AChE and BChE, displaying IC50 values of 125.06 nM and 119.68 nM, respectively. Additionally, AChE/BChE-IN-17 inhibits α-glucosidase, with an IC50 of 41050 nM.</p>Formule :C28H25N3O4Masse moléculaire :467.18451sn-Glycerol 3-phosphate lithium
<p>Lithium sn-glycerol 3-phosphate made by converting dihydroxyacetone phosphate via NADH from glycolysis.</p>Couleur et forme :Solid4-Phytase
CAS :<p>4-Phytase is a phosphohydrolase of inositol hexaphosphate [1] .</p>Couleur et forme :Solidω-Conotoxin CVIE
<p>ω-Conotoxin CVIE selectively inhibits voltage-gated Ca^2+ channels (Ca_v 2.2) [1].</p>Formule :C98H164N40O34S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2638.99HIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Couleur et forme :Odour SolidIrsenontrine maleate
CAS :<p>Irsenontrine (E2027) maleate is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9). It can be utilized in the study of neurological diseases.</p>Formule :C26H26N4O7Couleur et forme :SolidMasse moléculaire :506.515DSPE-PEG-Maleimide ammonium (MW 2000)
<p>DSPE-PEG-Maleimide (ammonium) (MW 2000) is a compound containing DSPE phospholipids and maleimide, designed for the preparation of nanoscale lipid carriers. It is applicable in the study of drug delivery systems.</p>Couleur et forme :Odour SolidAdenylosuccinic acid tetraammonium
<p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>Formule :C14H30N9O11PCouleur et forme :SolidMasse moléculaire :531.42PDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Couleur et forme :Odour SolidGlutarylcarnitine lithium
<p>Glutarylcarnitine lithium indicates malonic aciduria, glutaric aciduria I in newborn screenings.</p>Formule :C12H20LiNO6Couleur et forme :SolidMasse moléculaire :281.23Theodrenaline hydrochloride
CAS :<p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>Formule :C17H22ClN5O5Degré de pureté :98% - 98.18%Couleur et forme :SoildMasse moléculaire :411.84
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