Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(165 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8628 produits trouvés pour "Métabolisme"
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Fumonisin B2
CAS :<p>Fumonisin B2, from Fusarium moniliforme in grains, blocks ceramide synthase, disrupting sphingolipid biosynthesis.</p>Formule :C34H59NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :705.83Glucoiberin potassium
CAS :Glucoiberin potassium is an active compound.Formule :C11H21KNO10S3Couleur et forme :SolidMasse moléculaire :462.58Etavopivat
CAS :<p>Etavopivat activates PKR in RBCs; taken orally, prevents sickling.</p>Formule :C22H23N3O6SCouleur et forme :SolidMasse moléculaire :457.5Penicillinase
CAS :<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Couleur et forme :SolidRat Factor Xa
<p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>Couleur et forme :Odour SolidPP5-IN-2
<p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>Formule :C16H15NO4Couleur et forme :SolidMasse moléculaire :285.29Alcohol oxidase
CAS :<p>Alcohol oxidase, a key enzyme in the methanol utilization pathway, is derived from yeast peroxisomes.</p>Couleur et forme :Solid10-FTHF
CAS :<p>10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.</p>Formule :C20H23N7O7Couleur et forme :SolidMasse moléculaire :473.44Histone acetyltransferase p300 Inhibitor 4c
CAS :<p>2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.</p>Formule :C9H7ClN2SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :210.68Epothilone C
CAS :<p>Epothilone C is a polyketide natural product. It is produced through the collaborative action of a nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) molecules within a multi-enzyme system. Epothilone C is utilized in tumor research.</p>Formule :C26H39NO5SCouleur et forme :SolidMasse moléculaire :477.657Corynecin IV
CAS :Corynecin IV is a metabolite similar to chloramphenicol, originally isolated from corynebacteria.Formule :C13H16N2O6Couleur et forme :SolidMasse moléculaire :296.276BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Couleur et forme :Odour SolidACAT-IN-10
CAS :<p>ACAT-IN-10, from EP1236468A1 ex. 197, is an ACAT inhibitor with mild NF-κB blocking action.</p>Formule :C35H56N4O5SCouleur et forme :SolidMasse moléculaire :644.92Coformycin
CAS :<p>Coformycin is a ribonucleoside antibiotic synergist and adenosine deaminase inhibitor.</p>Formule :C11H16N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.27N-Acetylhexosamine kinase (NahK)
CAS :<p>NahK phosphorylates GlcNAc/GalNAc at C1 using ATP to form GlcNAc-1P/GalNAc-1P.</p>Couleur et forme :Solid(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid
CAS :<p>'(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid, a saponin isolated from Rubus ellipticus var.</p>Formule :C30H46O7Couleur et forme :SolidMasse moléculaire :518.68α-Amylase/α-Glucosidase-IN-17
<p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>Formule :C19H18FNOCouleur et forme :SolidMasse moléculaire :295.35Micafungin metabolite M1
CAS :<p>Micafungin metabolite M1 is an active metabolite of Micafungin, generated through metabolism by arylsulfatase, and exhibits antifungal activity. It can be utilized in research on deep fungal infections caused by Candida species (Candidiasis) and Aspergillus species (Aspergillosis).</p>Formule :C56H71N9O20Couleur et forme :SolidMasse moléculaire :1190.21Nampt-IN-10 trihydrochloride
<p>Nampt-IN-10 trihydrochloride, a NAMPT inhibitor, is effective on A2780 & CORL23 cells (IC50: 5/19 nM); potential ADC payload.</p>Formule :C27H31Cl3FN5O2Couleur et forme :SolidMasse moléculaire :582.92Fenbendazole sulfone
CAS :<p>Fenbendazole sulfone is a minor metabolite of fenbendazole, exhibiting inhibitory activity against 7-ethoxycoumarin O-deethylase in rat liver.</p>Formule :C15H13N3O4SDegré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :331.3511(R)-HETE
CAS :<p>11(R)-HETE aids in oocyte maturation in sea urchins and tentacle regeneration in hydras; it is also made by aspirin-influenced COX-2 and arachidonic acid.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473L-Proline-15N
CAS :<p>L-Proline-15N is an isotopically labeled amino acid suitable for metabolic research, aiding in the exploration of amino acid metabolism pathways and mechanisms.</p>Formule :C5H9NO2Couleur et forme :SolidMasse moléculaire :116.12DG013A formate
<p>DG013A (formate) is a tripeptide-mimicking inhibitor of hypophosphorous acid. It exhibits IC50 values of 33 nM for ERAP1 and 11 nM for ERAP2. This compound can be utilized in research related to autoimmune diseases and cancer.</p>Formule :C27H37N4O4PCH2O2Couleur et forme :SolidMasse moléculaire :530.99C14-490
CAS :<p>C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).</p>Formule :C86H177N5O7Couleur et forme :SolidMasse moléculaire :1393.35DSPE-PEG5000-TH
<p>DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.</p>Couleur et forme :Odour Solid(5S)-Neosamine C
CAS :<p>(5S)-Neosamine C, an aminocyclic alcohol antibiotic derived from microbial secondary metabolites, possesses a cyclized structure and is utilized in the biosynthesis of Neomycins.</p>Formule :C6H14N2O4Couleur et forme :SolidMasse moléculaire :178.19Secalciferol
CAS :<p>Secalciferol is a Vitamin D metabolite,Secalciferol is a possibly anti-inflammatory steroid which is involved in bone ossification.</p>Formule :C27H44O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.64ROR1-IN-2
<p>ROR1-IN-2 (compound 9I) is a potent and selective inhibitor of ROR1. It exhibits antiproliferative activity in various cancer cell lines and significantly inhibits tumor growth in vivo.</p>Formule :C30H27N3O4Couleur et forme :SolidMasse moléculaire :493.20016ACSS2-IN-2
CAS :<p>MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.</p>Formule :C21H19F2N3O4Degré de pureté :99.5%Couleur et forme :SoildMasse moléculaire :415.39(±)18-HETE
CAS :<p>(±)18-HETE (18-Hydroxyeicosatetraenoic acid) is an arachidonic acid metabolite with a hydroxyl group on carbon 18, catalyzed by cytochrome P-450.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47DSPE-PEG1000-EB1
<p>DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.</p>Couleur et forme :Odour SolidPTP1B-IN-25
<p>PTP1B-IN-25 (Compound 19) is an inhibitor of PTP1B with notable antiviral, antibacterial, and antidiabetic activities. It exhibits IC50 values of 0.37 μM for PTP1B, 8.6 μM for HIV, 3.7 μM for α-Glucosidase, and 29 μM for methicillin-resistant Staphylococcus aureus (MRSA).</p>Formule :C44H66O17Masse moléculaire :866.43DSPE-PEG1000-LTLRWVGLMS
<p>DSPE-PEG1000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). The receptor for LLRWVGLMS is the chondroitin sulfate proteoglycan NG2. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG1000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour SolidPFKFB3-IN-2
CAS :PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.Formule :C14H11NO7SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :337.3Prostaglandin F2β
CAS :<p>Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α.</p>Formule :C20H34O5Couleur et forme :White SolidMasse moléculaire :354.48SW209049
CAS :<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Formule :C25H18N2O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :442.49Di-O-demethylcurcumin
CAS :<p>Di-O-demethylcurcumin (Bisdemethylcurcumin) is an intestinal metabolite of curcumin known for its neuroprotective properties.</p>Formule :C19H16O6Couleur et forme :SolidMasse moléculaire :340.33PF-03049423
CAS :<p>PF-03049423: potent, selective PDE-5A inhibitor, IC50 ~0.2 nM, for rat/human thrombomodulin; used in ischemic stroke research.</p>Formule :C24H32N6O4Degré de pureté :99.89% - 99.93%Couleur et forme :SolidMasse moléculaire :468.55DSPE-PEG2000-PP1
<p>DSPE-PEG2000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide specifically targets inflammatory atherosclerotic plaques. DSPE-PEG2000-PP1 is utilized in drug delivery applications.</p>Couleur et forme :Odour SolidDaclatasvir Impurity B
CAS :<p>Daclatasvir Impurity B, a noted impurity of the antiviral agent Daclatasvir, acts as a potent inhibitor of the HCV NS5A protein [1].</p>Formule :C35H41N7O4Couleur et forme :SolidMasse moléculaire :623.74DSPE-PEG5000-LTLRWVGLMS
<p>DSPE-PEG5000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 serves as a receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG5000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour SolidOsmanthuside H
CAS :<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.422Aspergillomarasmine A
CAS :<p>Aspergillomarasmine A is a polyamine acid naturally produced by the mold Aspergillus Versicolor.</p>Formule :C10H17N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :307.26Inulobiose
CAS :<p>Inulobiose, a difructan disaccharide isolated from Pistacia vera L., demonstrates inhibitory effects on α-glycosidase (α-glycosidase) and α-amylase (α-amylase) activities, with IC50 values of 1.87 and 40.72 mg/mL respectively. It is utilized in research related to diabetes and glomerular filtration rate testing.</p>Formule :C12H22O11Couleur et forme :SolidMasse moléculaire :342.3LY 135114
CAS :<p>LY 135114 is a metabolite of LY 195448, which is a phenethanolamine with anti-tumour activity.</p>Formule :C20H26N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.43Sinbaglustat
CAS :<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formule :C11H23NO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :233.3Phytin
CAS :<p>Phytin has a wide range of applications in life science related research.</p>Formule :C6H6CaMgO24P6Couleur et forme :White PowderMasse moléculaire :712.32Erucic acid sodium
CAS :Erucic acid sodium, a monounsaturated fatty acid (MUFA) extracted from the seeds of rapeseed, readily crosses the blood-brain barrier (BBB). It normalizes the accumulation of long-chain fatty acids in the brain, enhances cognitive function, and effectively prevents dementia.Formule :C22H42NaO2Couleur et forme :SolidMasse moléculaire :361.56CUDA
CAS :<p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>Formule :C19H36N2O3Degré de pureté :97.585%Couleur et forme :SolidMasse moléculaire :340.5DL-TBOA ammonium
CAS :<p>DL-TBOA ammonium is a potent EAAT inhibitor with IC50 (6-70 μM) and Ki (3.2-42 μM) against EAAT1-5, blocking [14C]glutamate uptake.</p>Formule :C11H16N2O5Couleur et forme :SolidMasse moléculaire :256.258
