Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(142 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5903 prodotti di "Apoptosi"
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3-Nitropropanoic acid
CAS:3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.Formula:C3H5NO4Purezza:98.35% - 99.94%Colore e forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecolare:119.08CCG-1423
CAS:CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formula:C18H13ClF6N2O3Purezza:99.80%Colore e forma:SolidPeso molecolare:454.75TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formula:C21H17ClN2O6Purezza:97.62% - 99.09%Colore e forma:SolidPeso molecolare:428.82Solamargine
CAS:Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.Formula:C45H73NO15Purezza:99.17% - 99.96%Colore e forma:SolidPeso molecolare:868.06Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purezza:98% - 99.93%Colore e forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecolare:376.57SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Xanthohumol
CAS:<p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>Formula:C21H22O5Purezza:98.19% - 99.67%Colore e forma:Orange PowderPeso molecolare:354.4NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formula:C23H20N2OPurezza:96.94%Colore e forma:SolidPeso molecolare:340.42Palmatine
CAS:<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Formula:C21H22NO4Purezza:96.28% - 99.49%Colore e forma:SolidPeso molecolare:352.4Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Formula:C29H36O6Purezza:98.74% - 99.82%Colore e forma:SolidPeso molecolare:480.59Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Formula:C50H71N13O12Purezza:95% - >99.99%Colore e forma:SolidPeso molecolare:1046.18Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formula:C51H34N6Na6O23S6Purezza:97.47% - 99.97%Colore e forma:WhitePeso molecolare:1429.15(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purezza:99.09% - 99.81%Colore e forma:SolidPeso molecolare:364.35PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurezza:99.13% - 99.83%Colore e forma:SolidPeso molecolare:369.22AZD0156
CAS:<p>AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.</p>Formula:C26H31N5O3Purezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:461.56TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Formula:C26H35N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:509.67Mancozeb
CAS:Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.Formula:C8H12MnN4S8ZnPurezza:98%Colore e forma:Grayish-Yellow PowderPeso molecolare:541.08MGCD-265 analog
CAS:<p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>Formula:C26H20FN5O2S2Purezza:98.06% - 98.68%Colore e forma:SolidPeso molecolare:517.6Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:432.46Echinocystic acid
CAS:<p>EA, a natural triterpene, is found in herbs; it has anti-inflammatory and antioxidant properties.</p>Formula:C30H48O4Purezza:98% - 99.57%Colore e forma:SolidPeso molecolare:472.7Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Formula:C42H72O14Purezza:99% - 99.92%Colore e forma:White Crystalline PowderPeso molecolare:801.01EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Formula:C19H15F2NOPurezza:99.71%Colore e forma:SolidPeso molecolare:311.33Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurezza:98.71%Colore e forma:SolidPeso molecolare:253.27McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Formula:C49H76N6O11Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:925.16Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormula:C54H90N6O18Purezza:95.37% - 97.16%Colore e forma:White SolidPeso molecolare:1111.32Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purezza:≥98%Colore e forma:SolidPeso molecolare:263.26CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Formula:C23H16N4OPurezza:99.16%Colore e forma:SolidPeso molecolare:364.4LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Formula:C33H43Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:584.62BMS-202
CAS:<p>BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.</p>Formula:C25H29N3O3Purezza:97.92% - 99.66%Colore e forma:SolidPeso molecolare:419.52CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Formula:C15H20ClN5O4Purezza:99.1%Colore e forma:Off-White To Light Yellow SolidPeso molecolare:369.8Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Formula:C33H34N6O6Purezza:98.22% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:610.66Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurezza:98% - 99.87%Colore e forma:SolidPeso molecolare:532.61NVP-ADW742
CAS:<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Formula:C28H31N5OPurezza:96.14% - 98.70%Colore e forma:SolidPeso molecolare:453.58Pevonedistat
CAS:<p>Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).</p>Formula:C21H25N5O4SPurezza:95% - 99.92%Colore e forma:SolidPeso molecolare:443.52TASIN-1 Hydrochloride
CAS:<p>TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated</p>Formula:C18H29ClN2O3SPurezza:99.94%Colore e forma:SolidPeso molecolare:388.95Paroxetine
CAS:Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.Formula:C19H20FNO3Purezza:98.59% - 98.89%Colore e forma:White To Off-White PowderPeso molecolare:329.37Isosorbide Mononitrate
CAS:Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formula:C6H9NO6Purezza:98.16%Colore e forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecolare:191.14Parcetasal
CAS:Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.Formula:C17H15NO5Purezza:99.07%Colore e forma:SolidPeso molecolare:313.3TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormula:C17H18ClNO3SPurezza:97.33%Colore e forma:PowderPeso molecolare:351.85Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:212.24PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Formula:C7H12N2S2Purezza:98% - 99.21%Colore e forma:SolidPeso molecolare:188.31L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Formula:C13H13ClN4OSPurezza:98.6% - 99.13%Colore e forma:SolidPeso molecolare:308.79Saquinavir
CAS:<p>Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.</p>Formula:C38H50N6O5Purezza:99.50% - >99.99%Colore e forma:SolidPeso molecolare:670.84SP2509
CAS:SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).Formula:C19H20ClN3O5SPurezza:98.82% - 99.53%Colore e forma:SolidPeso molecolare:437.9Tenilsetam
CAS:<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Formula:C8H10N2OSPurezza:99.52%Colore e forma:SolidPeso molecolare:182.244-IBP
CAS:4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .Formula:C19H21IN2OPurezza:98.99%Colore e forma:SolidPeso molecolare:420.29Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Formula:C20H32F2O5Purezza:97.31% - 98.54%Colore e forma:White Odorless Crystals Or Crystalline PowderPeso molecolare:390.46RH01687
CAS:RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.Formula:C12H9ClN6O2SPurezza:97.93%Colore e forma:SolidPeso molecolare:336.76Clodronic acid disodium salt
CAS:<p>Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.</p>Formula:CH4Cl2O6P0·2NaPurezza:>99.99% - ≥98%Colore e forma:White SolidPeso molecolare:288.86Sodium benzoate
CAS:<p>Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.</p>Formula:C7H5NaO2Purezza:99.72%Colore e forma:White Solid CrystallinePeso molecolare:144.10HX 531
CAS:HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.Formula:C29H29N3O4Purezza:98.59% - 99.86%Colore e forma:SolidPeso molecolare:483.56Benzarone
CAS:Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.Formula:C17H14O3Purezza:99.77%Colore e forma:SolidPeso molecolare:266.29A-1210477
CAS:A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).Formula:C46H55N7O7SPurezza:99.17% - 99.37%Colore e forma:SolidPeso molecolare:850.043-hydroxy-3-phenylpentanamide
CAS:<p>Chiral 3-hydroxy-3-phenylpentanamide: neuroprotective, may treat anxiety/depression/addiction, anticancer.</p>Formula:C11H15NO2Purezza:98.42%Colore e forma:SolidPeso molecolare:193.24Ceftiofur
CAS:<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Formula:C19H17N5O7S3Purezza:98.26%Colore e forma:SolidPeso molecolare:523.56Epoxiconazole
CAS:<p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>Formula:C17H13ClFN3OPurezza:98.57%Colore e forma:Solid PowderPeso molecolare:329.76PATULIN
CAS:Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.Formula:C7H6O4Purezza:99.91% - 99.98%Colore e forma:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallinePeso molecolare:154.12Semaglutide
CAS:Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).Formula:C187H291N45O59Purezza:96.92% - 99.78%Colore e forma:SolidPeso molecolare:4114(Rac)-Antineoplaston A10
CAS:<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Formula:C13H14N2O3Purezza:98.41%Colore e forma:SolidPeso molecolare:246.26NSC 3852
CAS:NSC 3852 is a potent inhibitor of histone deacetylase.Formula:C9H6N2O2Purezza:99.64%Colore e forma:Slightly Yellow To Yellow-Green PowderPeso molecolare:174.163,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Formula:C9H4Cl2O2Purezza:97.94%Colore e forma:SolidPeso molecolare:215.03Thalidomide-NH-CH2-COOH TFA
CAS:2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.Formula:C17H14F3N3O8Purezza:95.00%Colore e forma:SolidPeso molecolare:445.3036Hexamethylene bisacetamide
CAS:Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.Formula:C10H20N2O2Purezza:99.94%Colore e forma:White FlakesPeso molecolare:200.28PDL-1 cpd 10
CAS:<p>PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.</p>Formula:C21H23N5O2Purezza:97.08%Colore e forma:SolidPeso molecolare:377.44NS-3-008 hydrochloride
CAS:<p>NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).</p>Formula:C14H24ClN3Purezza:99.56%Colore e forma:SolidPeso molecolare:269.81Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Formula:C24H30N2O2SPurezza:99.9% - 99.92%Colore e forma:SolidPeso molecolare:410.57(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Formula:C18H15N5O6S2Purezza:97.62% - 98%Colore e forma:SolidPeso molecolare:461.47OTS964 hydrochloride
CAS:<p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>Formula:C23H24N2O2S·HClPurezza:96.5% - 98.03%Colore e forma:SolidPeso molecolare:428.97Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Formula:C21H28FN3O7Purezza:98.24% - 99.79%Colore e forma:SolidPeso molecolare:453.46Sinapinic Acid
CAS:<p>Sinapinic Acid (Synapoic acid) is a phenolic isolated from the roots of Hydnophytum formicarumJack. It is an HDAC inhibitor and also inhibits ACE-I activity.</p>Formula:C11H12O5Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:224.21PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purezza:99.40%Colore e forma:SolidPeso molecolare:557.56Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Euscaphic acid
CAS:Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.Formula:C30H48O5Purezza:98.93%Colore e forma:SolidPeso molecolare:488.7Licochalcone B
CAS:Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.Formula:C16H14O5Purezza:99.33% - 99.9%Colore e forma:SolidPeso molecolare:286.28Oxibendazole
CAS:Oxibendazole: a benzimidazole antiparasitic for horses and pets against various worms.Formula:C12H15N3O3Purezza:99.3% - 99.88%Colore e forma:Crystalline SolidPeso molecolare:249.27Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purezza:99.53% - 99.79%Colore e forma:SolidPeso molecolare:553.59ZM 336372
CAS:ZM 336372 is a potent and selective c-Raf inhibitor.Formula:C23H23N3O3Purezza:97.24% - 97.51%Colore e forma:SolidPeso molecolare:389.45Hirsutine
CAS:Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive andFormula:C22H28N2O3Purezza:99.36% - 99.98%Colore e forma:SolidPeso molecolare:368.47PhiKan 083
CAS:<p>PhiKan 083 is a carbazole derivative</p>Formula:C16H18N2Purezza:98.37%Colore e forma:SolidPeso molecolare:238.33Aurintricarboxylic acid
CAS:Aurintricarboxylic acid (NSC-4056) blocks nucleases and topoisomerases, stopping nucleic acid binding.Formula:C22H14O9Purezza:97.1%Colore e forma:Deep Red Coarse Crystalline PowderPeso molecolare:422.34Avelumab
CAS:Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.Purezza:95% - 97.17% (SDS-PAGE)Colore e forma:LiquidPeso molecolare:143.8 kDaEvofosfamide
CAS:<p>Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage and potentially induce apoptosis.</p>Formula:C9H16Br2N5O4PPurezza:98.74% - 99.75%Colore e forma:SolidPeso molecolare:449.04Buparlisib
CAS:Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).Formula:C18H21F3N6O2Purezza:95.32% - 98.45%Colore e forma:SolidPeso molecolare:410.39NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purezza:97.66% - 98%Colore e forma:SolidPeso molecolare:362.23Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purezza:98.8% - 99.33%Colore e forma:SolidPeso molecolare:418.35AT7519 Hydrochloride
CAS:AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formula:C16H18Cl3N5O2Purezza:99.66% - 99.9%Colore e forma:SolidPeso molecolare:418.71Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Formula:C22H28N4O6Purezza:96.29% - 98.74%Colore e forma:Blue PowderPeso molecolare:444.48Amsilarotene
CAS:Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formula:C20H27NO3Si2Purezza:98.05%Colore e forma:SolidPeso molecolare:385.6Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Formula:C22H34N4O13Purezza:98.54%Colore e forma:SolidPeso molecolare:562.52Estramustine phosphate sodium
CAS:Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.Formula:C23H30Cl2NNa2O6PPurezza:96.44% - 99.54%Colore e forma:SolidPeso molecolare:564.35Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Formula:C19H20N4O·C7H8O3SPurezza:99.34% - 99.87%Colore e forma:SolidPeso molecolare:492.59Rigosertib sodium
CAS:<p>Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.</p>Formula:C21H24NNaO8SPurezza:98% - 99.37%Colore e forma:SolidPeso molecolare:473.47Tenovin-1
CAS:Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formula:C20H23N3O2SPurezza:99.33%Colore e forma:SolidPeso molecolare:369.48Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurezza:97.78% - 98%Colore e forma:SolidPeso molecolare:402.66SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formula:C21H21BrN4O5Purezza:99.13%Colore e forma:SolidPeso molecolare:489.322,5-dimethyl Celecoxib
CAS:2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.Formula:C18H16F3N3O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:395.4SRS16-86
CAS:<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Formula:C26H32N4O2Purezza:97.73%Colore e forma:SolidPeso molecolare:432.56Dantrolene
CAS:Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.Formula:C14H10N4O5Purezza:99.97%Colore e forma:Crystals From Aq DimethylformamidePeso molecolare:314.25Iberdomide
CAS:Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).Formula:C25H27N3O5Purezza:97.01%Colore e forma:SolidPeso molecolare:449.5
