Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(137 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(94 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6231 prodotti di "Apoptosi"
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OTS514 hydrochloride
CAS:OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).Formula:C21H20N2O2S·HClPurezza:99.67% - 99.84%Colore e forma:SolidPeso molecolare:400.92Ref: TM-T4134
1mg58,00€2mg92,00€5mg165,00€1mL*10mM (DMSO)165,00€10mg290,00€25mg527,00€50mg710,00€100mg898,00€500mg1.791,00€Kynurenic acid sodium
CAS:Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.Formula:C10H6NNaO3Purezza:99.47%Colore e forma:SolidPeso molecolare:211.15Metformin glycinate
CAS:Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Formula:C6H16N6O2Colore e forma:SolidPeso molecolare:204.23Fasentin
CAS:Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.Formula:C11H9ClF3NO2Purezza:99.95%Colore e forma:SolidPeso molecolare:279.64Ref: TM-T8616
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg93,00€25mg152,00€50mg222,00€100mg333,00€200mg495,00€Dihydrokaempferol
CAS:Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.Formula:C15H12O6Purezza:97.79% - 99.96%Colore e forma:SolidPeso molecolare:288.25SKLB-163
CAS:SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.Formula:C18H16ClN3O2S2Purezza:99.23%Colore e forma:SolidPeso molecolare:405.92Ref: TM-T26193
1mg128,00€5mg303,00€1mL*10mM (DMSO)335,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€500mg2.673,00€MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formula:C20H20N2OPurezza:98.17% - 99.754%Colore e forma:SolidPeso molecolare:304.39Ref: TM-T6886
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg245,00€50mg358,00€100mg537,00€PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurezza:98.74% - 99.19%Colore e forma:SolidPeso molecolare:347.39MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurezza:99.23% - 99.84%Colore e forma:SolidPeso molecolare:472.08Ref: TM-T6893
1mg34,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg105,00€25mg205,00€50mg334,00€100mg512,00€200mg732,00€Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33Ref: TM-T1847
5mg34,00€10mg50,00€1mL*10mM (DMSO)50,00€25mg78,00€50mg107,00€100mg166,00€200mg236,00€500mg398,00€ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Ref: TM-T8375
1mg34,00€2mg49,00€5mg82,00€1mL*10mM (DMSO)86,00€10mg133,00€25mg234,00€50mg393,00€100mg528,00€Prexasertib
CAS:Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Formula:C18H19N7O2Purezza:97.3% - 98.23%Colore e forma:SolidPeso molecolare:365.39Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3Ref: TM-T3S0153
50mgPrezzo su richiesta1mg49,00€5mg92,00€1mL*10mM (DMSO)113,00€10mg166,00€25mg268,00€FX1
CAS:FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).Formula:C14H9ClN2O4S2Purezza:97.59%Colore e forma:SolidPeso molecolare:368.82CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurezza:98.18% - >99.99%Colore e forma:SolidPeso molecolare:306.4Ref: TM-T3971
1mg35,00€2mg50,00€5mg71,00€1mL*10mM (DMSO)71,00€10mg114,00€25mg178,00€50mg268,00€100mg413,00€500mg888,00€SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formula:C16H11ClF3N3O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:401.79Thalidomide-PEG4-Propargyl
CAS:Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.Formula:C24H28N2O9Purezza:97.46%Colore e forma:SolidPeso molecolare:488.49CP-461 free base
CAS:CP-461 (OSI-461) is a pde2a / 5A inhibitor, which may be used in the treatment of renal cell carcinoma, prostate cancer, and Crohn's disease.Formula:C25H21FN2OColore e forma:SolidPeso molecolare:384.45CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purezza:98.84%Colore e forma:SolidPeso molecolare:411.41Ref: TM-T8652
1mg34,00€5mg71,00€1mL*10mM (DMSO)86,00€10mg105,00€25mg215,00€50mg344,00€100mg532,00€200mg740,00€NU 7026
CAS:NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFormula:C17H15NO3Purezza:99.51% - >99.99%Colore e forma:SolidPeso molecolare:281.31INH1
CAS:INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.Formula:C18H16N2OSPurezza:99.80%Colore e forma:SolidPeso molecolare:308.44EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurezza:96.8% - 99.12%Colore e forma:SolidPeso molecolare:451.28Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purezza:98% - 99.93%Colore e forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecolare:376.57SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Ref: TM-T2170
5mg54,00€1mL*10mM (DMSO)59,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€Xanthohumol
CAS:Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-Formula:C21H22O5Purezza:98.19% - 99.67%Colore e forma:Orange PowderPeso molecolare:354.40NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formula:C23H20N2OPurezza:96.94%Colore e forma:SolidPeso molecolare:340.425-Geranoxy-7-methoxycoumarin
CAS:5-Geranoxy-7-methoxycoumarin shows antifungal activity.Formula:C20H24O4Purezza:98.94% - 99.99%Colore e forma:SolidPeso molecolare:328.4Ref: TM-TN3110
1mg99,00€5mg231,00€1mL*10mM (DMSO)244,00€10mg343,00€25mg575,00€50mg802,00€100mg1.108,00€Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formula:C21H22NO4Purezza:96.28% - 99.49%Colore e forma:SolidPeso molecolare:352.4Dapivirine HCl
CAS:Dapivirine HCl (TMC120) is a salt-based non-nucleoside HIV reverse transcriptase inhibitor with an IC50 of 24 nM, used in HIV-1 prevention.Formula:C20H20ClN5Colore e forma:SolidPeso molecolare:365.86Navitoclax dihydrochloride
CAS:Navitoclax dihydrochloride is a synthetic Bcl-2 antagonist with potential cancer-fighting properties.Formula:C47H57Cl3F3N5O6S3Colore e forma:SolidPeso molecolare:1047.54CAY10703
CAS:DCA blocks PDHK in mitochondria, shifting metabolism and aiding in cancer and diabetes treatment. CAY10703, a potent DCA form, targets leukemia cells.Formula:C12H18Cl6N4O3Colore e forma:SolidPeso molecolare:479.01UMI-77
CAS:UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.Formula:C18H14BrNO5S2Purezza:96% - 99.57%Colore e forma:SolidPeso molecolare:468.34Ref: TM-T6034
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)86,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€200mg692,00€500mg1.035,00€RIPA-56
CAS:RIPA-56 is an inhibitor of RIP1Formula:C13H19NO2Purezza:99.53% - 99.93%Colore e forma:SolidPeso molecolare:221.3Ref: TM-T7795
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg89,00€50mg129,00€100mg202,00€200mg299,00€500mg504,00€Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formula:C51H34N6Na6O23S6Purezza:97.47% - 99.97%Colore e forma:WhitePeso molecolare:1429.15Laquinimod sodium
CAS:Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.Formula:C19H16ClN2NaO3Colore e forma:SolidPeso molecolare:378.79Quinacrine acetate
CAS:Quinacrine acetate is a histamine N-methyltransferase inhibitor.Formula:C25H34ClN3O3Colore e forma:SolidPeso molecolare:460.01(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purezza:99.09% - 99.81%Colore e forma:SolidPeso molecolare:364.35Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purezza:99.8% - ≥95%Colore e forma:White CrystalPeso molecolare:307.43Ziyuglycoside I
CAS:Ziyuglycoside I (Gouguside 7) has anti-inflammatory activity, could be used as an active ingredient for cosmetics.Formula:C41H66O13Purezza:98.987% - ≥95%Colore e forma:SolidPeso molecolare:766.95Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purezza:97.1% - 99.93%Colore e forma:SolidPeso molecolare:558.70AZD0156
CAS:AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.Formula:C26H31N5O3Purezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:461.56Scopoletin
CAS:Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).Formula:C10H8O4Purezza:97.06% - 99.88%Colore e forma:Yellow To Beige Crystalline PowderPeso molecolare:192.17Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purezza:96.39% - 99.29%Colore e forma:SolidPeso molecolare:394.42HS-1793
CAS:HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.Formula:C16H12O3Purezza:98.16% - 99.82%Colore e forma:SolidPeso molecolare:252.26Thalidomide-O-C4-NH2 hydrochloride
CAS:Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.Formula:C17H20ClN3O5Purezza:98.33%Colore e forma:SolidPeso molecolare:381.81Bardoxolone
CAS:Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.Formula:C31H41NO4Purezza:97.9% - 98.97%Colore e forma:SolidPeso molecolare:491.66AS1842856
CAS:AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formula:C18H22FN3O3Purezza:99.36% - >99.99%Colore e forma:SolidPeso molecolare:347.38QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurezza:99.17% - 99.18%Colore e forma:White SolidPeso molecolare:356.42Ref: TM-T6204
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg133,00€25mg178,00€50mg313,00€100mg465,00€200mg673,00€JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purezza:98.02% - 98.4%Colore e forma:SolidPeso molecolare:451.3Ref: TM-T37314
1mg49,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg281,00€50mg439,00€100mg708,00€200mg964,00€
