Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

Mostrare 10 più sottocategorie

Trovati 3480 prodotti di "Ciclo cellulare/Checkpoint"

Purezza (%)

100

prodotti per pagina.

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Trilaciclib hydrochloride
CAS:
- 1977495-97-8
Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).
Formula:C₂₄H₃₂Cl₂N₈O
Purezza:99.69% - 99.89%
Colore e forma:Solid
Peso molecolare:519.47
Ref: TM-T13202
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MYCi975
CAS:
- 2289691-01-4
MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.
Formula:C₂₅H₁₆Cl₂F₆N₂O₂
Purezza:99.3% - 99.82%
Colore e forma:Solid
Peso molecolare:561.3
Ref: TM-T12133
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SU056
CAS:
- 2376580-08-2
SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
Formula:C₂₀H₁₆FNO₅
Purezza:99.89%
Colore e forma:Soild
Peso molecolare:369.34
Ref: TM-T67741
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Enrofloxacin
CAS:
- 93106-60-6
Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
Formula:C₁₉H₂₂FN₃O₃
Purezza:99.43% - >99.99%
Colore e forma:Pale Yellow Crystals
Peso molecolare:359.39
Ref: TM-T1617
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NU6140
CAS:
- 444723-13-1
NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).
Formula:C₂₃H₃₀N₆O₂
Purezza:98.33%
Colore e forma:Solid
Peso molecolare:422.52
Ref: TM-T16359
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TAK-901
CAS:
- 934541-31-8
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others
Formula:C₂₈H₃₂N₄O₃S
Purezza:99.02% - 99.59%
Colore e forma:Solid
Peso molecolare:504.64
Ref: TM-T2709
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R-10015
CAS:
- 2097938-51-5
R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.
Formula:C₂₀H₁₉ClN₆O₂
Purezza:98.68%
Colore e forma:Solid
Peso molecolare:410.86
Ref: TM-T12609
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Metarrestin
CAS:
- 1443414-10-5
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
Formula:C₃₁H₃₀N₄O
Purezza:99.45%
Colore e forma:Solid
Peso molecolare:474.6
Ref: TM-T12006
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Abrilumab
CAS:
- 1342290-43-0
Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.
Purezza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)
Colore e forma:Liquid
Ref: TM-T76737
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Tadocizumab
CAS:
- 339086-80-5
Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.
Purezza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)
Colore e forma:Liquid
Ref: TM-T76979
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CDK2-IN-4
CAS:
- 2079895-42-2
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.
Formula:C₂₃H₁₈N₆O₂S
Purezza:97.24% - 99.10%
Colore e forma:Solid
Peso molecolare:442.49
Ref: TM-T14916
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Ribociclib succinate
CAS:
- 1374639-75-4
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).
Formula:C₂₇H₃₆N₈O₅
Purezza:99.9%
Colore e forma:Solid
Peso molecolare:552.63
Ref: TM-T15732
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JH-RE-06
CAS:
- 1361227-90-8
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.
Formula:C₂₀H₁₆Cl₃N₃O₄
Purezza:99.29%
Colore e forma:Solid
Peso molecolare:468.72
Ref: TM-T15611
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Mps1-IN-3
CAS:
- 1609584-72-6
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
Formula:C₂₆H₃₁N₇O₄S
Purezza:99.25%
Colore e forma:Solid
Peso molecolare:537.63
Ref: TM-T16130
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GSK-1520489A
CAS:
- 1042433-41-9
GSK-1520489A is an active PKMYT1 inhibitor.
Formula:C₂₁H₂₃N₅O₃S
Purezza:99.85%
Colore e forma:Solid
Peso molecolare:425.5
Ref: TM-T9966
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Vitamin D2
CAS:
- 50-14-6
Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.
Formula:C₂₈H₄₄O
Purezza:98.73% - 99.89%
Colore e forma:Prisms From Acetone 1998)
Peso molecolare:396.65
Ref: TM-T1086
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DI-87
CAS:
- 2107280-55-5
DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.
Formula:C₂₃H₃₀N₆O₃S₂
Purezza:99.76%
Colore e forma:Solid
Peso molecolare:502.65
Ref: TM-T39550
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Hycanthone
CAS:
- 3105-97-3
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.
Formula:C₂₀H₂₄N₂O₂S
Purezza:98.78%
Colore e forma:Yellow-Orange Powder (Ntp 1992)
Peso molecolare:356.48
Ref: TM-T15507
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XPW1
CAS:
- 2700286-66-2
XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.
Formula:C₃₆H₃₉ClFN₇O₂
Purezza:98.08%
Colore e forma:Soild
Peso molecolare:656.19
Ref: TM-T77810
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Efalizumab
CAS:
- 214745-43-4
Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.
Purezza:SDS-PAGE:95% SEC-HPLC:98.77%
Colore e forma:Liquid
Peso molecolare:146.14 kDa
Ref: TM-T76924