Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(522 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(180 prodotti)
- Integrina(256 prodotti)
- Chinesina(85 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(285 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(67 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(75 prodotti)
Mostrare 10 più sottocategorie
Trovati 3739 prodotti di "Ciclo cellulare/Checkpoint"
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Rev 2'-O-MOE-5MeC(Bz)-5'-amidite
Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formula:C50H60N5O10PColore e forma:SolidPeso molecolare:922.01Eesperamicin A1
CAS:Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.Formula:C59H80N4O22S4Colore e forma:SolidPeso molecolare:1325.54UnyLinker 12 TEA
UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.Formula:C39H35NO10C6H15NColore e forma:SolidPeso molecolare:778.346556-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical andFormula:C10H17N7O3Colore e forma:SolidPeso molecolare:283.29RNA splicing modulator 2
CAS:RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .Formula:C20H21N5OSColore e forma:SolidPeso molecolare:379.48STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Purezza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Colore e forma:Odour LiquidPD-1/PD-L1-IN-50
Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.Colore e forma:Odour SolidLXY3
CAS:LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.Formula:C32H43N11O15S2Colore e forma:SolidPeso molecolare:885.882'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effectiveFormula:C34H75FN9O12P3Colore e forma:SolidPeso molecolare:913.933,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential antiFormula:C23H45N3O5Si2Colore e forma:SolidPeso molecolare:499.79Heliquinomycin
CAS:Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.Formula:C33H30O17Colore e forma:SolidPeso molecolare:698.586CDK7-IN-6
CAS:CDK7-IN-6, a potent CDK7 inhibitor (IC50 ≤100 nM), from WO2019197549 A1, is >200x selective over CDK1/2/5, promising for cancer research.Formula:C26H34ClN9OColore e forma:SolidPeso molecolare:524.07N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
<p>N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoid</p>Formula:C16H16FN3O5Colore e forma:SolidPeso molecolare:349.31N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Formula:C14H21N5O5Colore e forma:SolidPeso molecolare:339.35(1S,3R,5R)-PIM447 dihydrochloride
<p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>Formula:C24H25Cl2F3N4OPurezza:98%Colore e forma:SolidPeso molecolare:513.385'-ODMT cEt G Phosphoramidite (Amidite)
CAS:5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Formula:C46H56N7O9PColore e forma:SolidPeso molecolare:881.95Anti-MRSA agent 7
Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.Formula:C22H20BrF2N3O4Colore e forma:SolidPeso molecolare:508.31L-Inosine
CAS:L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.Formula:C10H12N4O5Colore e forma:SolidPeso molecolare:268.23Chrysomycin A
CAS:Chrysomycin A is an antibiotic that can be derived from Streptomyces.Formula:C28H28O9Colore e forma:SolidPeso molecolare:508.52TTK/PLK1-IN-1
CAS:TTK/PLK1-IN-1 (Formula I) is a dual inhibitor of TTK (threonine tyrosine kinase) and PLK1 (polo-like kinase 1), with IC₅₀ values of 7 nM and 72 nM respectively.Formula:C30H33N7O2Purezza:97.39%Colore e forma:SolidPeso molecolare:523.63
