Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(522 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(180 prodotti)
- Integrina(256 prodotti)
- Chinesina(85 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(285 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(67 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(75 prodotti)
Mostrare 10 più sottocategorie
Trovati 3739 prodotti di "Ciclo cellulare/Checkpoint"
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Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Purezza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Colore e forma:LiquidPeso molecolare:145.79 kDaMKC8866
CAS:<p>MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.</p>Formula:C18H19NO7Purezza:99.28% - 99.854%Colore e forma:SolidPeso molecolare:361.356-Mercaptopurine
CAS:6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.Formula:C5H4N4SPurezza:99.53% - 99.63%Colore e forma:Yellow Crystalline Powder SolidPeso molecolare:152.18Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H20FN3O4H2OPurezza:98.26%Colore e forma:Pale Yellow SolidPeso molecolare:370.38Carmofur
CAS:Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Formula:C11H16FN3O3Purezza:98.53% - 99.98%Colore e forma:SolidPeso molecolare:257.26Orbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formula:C19H24F3N5O6Purezza:97.21% - 98.72%Colore e forma:SolidPeso molecolare:475.42TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Formula:C28H32N4O3SPurezza:99.02% - 99.59%Colore e forma:SolidPeso molecolare:504.64Abciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Purezza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Colore e forma:LiquidPeso molecolare:95.18 kDaRifaximin
CAS:Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.Formula:C43H51N3O11Purezza:99.18% - 99.40%Colore e forma:Red-Orange Crystalline PowderPeso molecolare:785.88HLM006474
CAS:HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).Formula:C25H25N3O2Purezza:99.04% - 99.20%Colore e forma:SolidPeso molecolare:399.48Tidutamab
CAS:Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).Purezza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Colore e forma:LiquidATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurezza:98% - 99.98%Colore e forma:SolidPeso molecolare:711.67Hu7691 free base
CAS:<p>Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.</p>Formula:C22H21F3N4OPurezza:98.89%Colore e forma:SolidPeso molecolare:414.423BMS-1001 hydrochloride
CAS:BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effectFormula:C35H35ClN2O7Purezza:97.36%Colore e forma:SolidPeso molecolare:631.11Trilaciclib hydrochloride
CAS:Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Formula:C24H32Cl2N8OPurezza:99.69% - 99.89%Colore e forma:SolidPeso molecolare:519.47NU6140
CAS:<p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>Formula:C23H30N6O2Purezza:98.33%Colore e forma:SolidPeso molecolare:422.52MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purezza:99.3% - 99.82%Colore e forma:SolidPeso molecolare:561.3Cirtuvivint
CAS:<p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>Formula:C24H25N7OPurezza:99.46% - >99.99%Colore e forma:SolidPeso molecolare:427.5Cinoxacin
CAS:<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Formula:C12H10N2O5Purezza:99.62% - 99.98%Colore e forma:SolidPeso molecolare:262.22Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purezza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Colore e forma:LiquidPeso molecolare:191.1 kDaButylparaben
CAS:Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.Formula:C11H14O3Purezza:98.15%Colore e forma:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Peso molecolare:194.23LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formula:C20H21N7O7Purezza:99.7%Colore e forma:SolidPeso molecolare:471.42BT173
CAS:BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.Formula:C18H12BrN3O2Purezza:98.247%Colore e forma:SolidPeso molecolare:382.21Procaine
CAS:<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Formula:C13H20N2O2Purezza:99.57% - 99.73%Colore e forma:Anhydrous Plates Tables From Ligroin Or Ether SolidPeso molecolare:236.31Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purezza:>95%Colore e forma:LiquidLerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Formula:C26H36Cl2N8OPurezza:97.4%Colore e forma:SolidPeso molecolare:547.52JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Formula:C20H16Cl3N3O4Purezza:99.29%Colore e forma:SolidPeso molecolare:468.72Foralumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Purezza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidMps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurezza:99.25%Colore e forma:SolidPeso molecolare:537.63BMVC-8C3O
CAS:BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.Formula:C42H53I3N4O3Purezza:99.72%Colore e forma:SolidPeso molecolare:1042.61GSK-1520489A
CAS:<p>GSK-1520489A is an active PKMYT1 inhibitor.</p>Formula:C21H23N5O3SPurezza:99.85%Colore e forma:SolidPeso molecolare:425.5Enrofloxacin
CAS:<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Formula:C19H22FN3O3Purezza:99.43% - >99.99%Colore e forma:Pale Yellow CrystalsPeso molecolare:359.39SU056
CAS:<p>SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.</p>Formula:C20H16FNO5Purezza:99.89%Colore e forma:SoildPeso molecolare:369.34R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Formula:C20H19ClN6O2Purezza:98.68%Colore e forma:SolidPeso molecolare:410.86XPW1
CAS:<p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>Formula:C36H39ClFN7O2Purezza:98.08%Colore e forma:SoildPeso molecolare:656.19Vitamin D2
CAS:Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.Formula:C28H44OPurezza:98.73% - 99.89%Colore e forma:Prisms From Acetone 1998)Peso molecolare:396.65Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purezza:SDS-PAGE:95% SEC-HPLC:98.77%Colore e forma:LiquidPeso molecolare:146.14 kDaHycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Formula:C20H24N2O2SPurezza:98.78%Colore e forma:Yellow-Orange Powder (Ntp 1992)Peso molecolare:356.48DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Formula:C23H30N6O3S2Purezza:99.76%Colore e forma:SolidPeso molecolare:502.65Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Formula:C18H16N8Na2O7S3·5H2OPurezza:99.77% - 99.78%Colore e forma:White Or Almost White Crystalline Powder OdorlessPeso molecolare:661.6Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purezza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidCyclin K degrader 1
Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.Formula:C23H17Cl2N5O2Purezza:99.76%Colore e forma:SolidPeso molecolare:466.32Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Formula:C31H30N4OPurezza:99.45%Colore e forma:SolidPeso molecolare:474.6Gemifloxacin mesylate
CAS:Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventuallyFormula:C19H24FN5O7SPurezza:97.24% - ≥95%Colore e forma:Beige SolidPeso molecolare:485.49hSMG-1 inhibitor 11j
CAS:<p>hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.</p>Formula:C27H28ClN7O3SPurezza:99.22% - 99.65%Colore e forma:SolidPeso molecolare:566.07Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Formula:C27H36N8O5Purezza:99.9%Colore e forma:SolidPeso molecolare:552.63CDK2-IN-4
CAS:<p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>Formula:C23H18N6O2SPurezza:97.24% - 99.10%Colore e forma:SolidPeso molecolare:442.49Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Purezza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:LiquidTAO Kinase inhibitor 2
CAS:<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Formula:C25H24N2O3Purezza:98.58%Colore e forma:SoildPeso molecolare:400.47Tegafur
CAS:<p>Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.</p>Formula:C8H9FN2O3Purezza:99.16% - 99.89%Colore e forma:White Crystalline PowderPeso molecolare:200.17
