Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(545 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(249 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(124 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3860 prodotti di "Ciclo cellulare/Checkpoint"
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Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Formula:C24H20N4O3SPurezza:99.26%Colore e forma:SolidPeso molecolare:444.51Ref: TM-T22282
1mg52,00€2mg65,00€5mg92,00€10mg161,00€25mg290,00€50mg420,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)110,00€Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formula:C20H21N7O7·CaPurezza:99.07% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:511.5Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurezza:97.51% - 99.51%Colore e forma:SolidPeso molecolare:427.32Ref: TM-T1911
1mg37,00€2mg52,00€5mg74,00€10mg92,00€25mg166,00€50mg259,00€100mg452,00€500mg982,00€1mL*10mM (DMSO)74,00€Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Formula:C19H20FN3O3Purezza:99.77% - 99.8%Colore e forma:SolidPeso molecolare:357.38CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Formula:C28H28N6O4Purezza:98.66% - 98.8%Colore e forma:SolidPeso molecolare:512.56Ref: TM-T4482
1mg50,00€5mg105,00€10mg170,00€25mg340,00€50mg512,00€100mg733,00€500mg1.513,00€1mL*10mM (DMSO)120,00€CHR-6494
CAS:CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Formula:C16H16N6Purezza:98.78%Colore e forma:SolidPeso molecolare:292.34Ref: TM-T14959
5mg54,00€10mg82,00€25mg145,00€50mg259,00€100mg442,00€200mg643,00€1mL*10mM (DMSO)60,00€FOY 251
CAS:FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.Formula:C17H19N3O7SPurezza:97.11% - 99.33%Colore e forma:SolidPeso molecolare:409.41Ref: TM-T8676
1mg51,00€5mg110,00€10mg177,00€25mg300,00€50mg424,00€100mg605,00€500mg1.198,00€1mL*10mM (DMSO)126,00€Calcium N5-methyltetrahydrofolate
CAS:Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFormula:C20H23CaN7O6Purezza:99.41%Colore e forma:SolidPeso molecolare:497.51AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Formula:C17H16ClN3OPurezza:98.04% - ≥95%Colore e forma:SolidPeso molecolare:313.78Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFormula:C25H23FN4OPurezza:98.38%Colore e forma:SolidPeso molecolare:414.47Ref: TM-T8873
1mg49,00€5mg104,00€10mg166,00€25mg325,00€50mg490,00€100mg737,00€500mg1.483,00€1mL*10mM (DMSO)115,00€Apcin
CAS:Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Formula:C13H14Cl3N7O4Purezza:96.74%Colore e forma:SolidPeso molecolare:438.65Ref: TM-T8561
1mg48,00€2mg63,00€5mg87,00€10mg140,00€25mg274,00€50mg472,00€100mg710,00€1mL*10mM (DMSO)97,00€Orbofiban
CAS:Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.Formula:C17H23N5O4Colore e forma:SolidPeso molecolare:361.4CKI-7 free base
CAS:CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H12ClN3O2SColore e forma:SolidPeso molecolare:285.75FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurezza:98.61%Colore e forma:SolidPeso molecolare:315.41Verosudil hydrochloride
CAS:Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS & OHT/XFG, offering a new treatment option.Formula:C17H18ClN3O2SColore e forma:SolidPeso molecolare:363.86Cedazuridine hydrochloride
Cedazuridine (E7727) hydrochloride is an oral cancer research drug blocking cytidine deaminase (IC50=0.4μM).Formula:C9H15ClF2N2O5Colore e forma:SolidPeso molecolare:304.68TAK-960 hydrochloride
CAS:TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Formula:C27H35ClF3N7O3Colore e forma:SolidPeso molecolare:598.06Rifamycin sodium
CAS:Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.Formula:C37H46NNaO12Purezza:97.72%Colore e forma:CoaPeso molecolare:719.75IRE1α kinase-IN-1
CAS:IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.
Formula:C26H26ClFN8Purezza:99.18%Colore e forma:SolidPeso molecolare:504.996-Chloropurine riboside
CAS:6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.Formula:C10H11ClN4O4Purezza:96.84%Colore e forma:SoildPeso molecolare:286.6700
