Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(544 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(47 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(230 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(119 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3831 prodotti di "Ciclo cellulare/Checkpoint"
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Preq1-Dihydrochloride
CAS:Preq1-Dihydrochloride, a queuosine pathway intermediate, binds strongly to PreQ1 riboswitch aptamer, suppressing protein expression.Formula:C7H11Cl2N5OPurezza:99.46%Colore e forma:SolidPeso molecolare:252.1GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Formula:C24H30Cl3N3OColore e forma:SolidPeso molecolare:482.87Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purezza:96.21%Colore e forma:SolidPeso molecolare:1198.5Mps1-IN-1 dihydrochloride
CAS:Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.Formula:C28H35Cl2N5O4SColore e forma:SolidPeso molecolare:608.58Ganciclovir hydrate
CAS:Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.Formula:C9H15N5O5Colore e forma:SolidPeso molecolare:273.249ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purezza:97.01% - 98.38%Colore e forma:SolidPeso molecolare:552.43USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Formula:C26H22F4N6OPurezza:99.69% - 99.88%Colore e forma:SolidPeso molecolare:510.486PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Formula:C23H26N6O4S2Purezza:99.14% - 99.21%Colore e forma:SolidPeso molecolare:514.62Ref: TM-T5700
5mg82,00€10mg137,00€25mg284,00€50mg424,00€100mg612,00€500mg1.264,00€1mL*10mM (DMSO)96,00€Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purezza:99.53%Colore e forma:SolidPeso molecolare:492.61PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:453.9Ref: TM-T84770
1mg84,00€5mg170,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€1mL*10mM (DMSO)195,00€CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formula:C18H15F5N8OPurezza:99.37%Colore e forma:SolidPeso molecolare:454.36Ref: TM-T40290
1mg157,00€5mg378,00€10mg612,00€25mg1.251,00€50mg1.972,00€100mg2.673,00€1mL*10mM (DMSO)416,00€LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Formula:C25H28F2N8Purezza:99.14%Colore e forma:SolidPeso molecolare:478.54Rabacfosadine
CAS:Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Formula:C21H35N8O6PPurezza:99.06% - 99.37%Colore e forma:SolidPeso molecolare:526.532'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formula:C10H12IN5O3Purezza:99.37%Colore e forma:SolidPeso molecolare:377.14RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formula:C24H19Cl3N2O4Purezza:98.26%Colore e forma:SolidPeso molecolare:505.78Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formula:C14H9ClN2O3SPurezza:98.56% - 99.42%Colore e forma:SolidPeso molecolare:320.752'-C-β-Methylguanosine
CAS:2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.Formula:C11H15N5O5Purezza:99.37%Colore e forma:SolidPeso molecolare:297.27N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormula:C18H21N5O5Purezza:99.79%Colore e forma:SolidPeso molecolare:387.39Ref: TM-TNU0430
1mg141,00€2mg203,00€5mg344,00€10mg505,00€25mg797,00€50mg1.044,00€100mg1.431,00€200mg1.953,00€2'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Formula:C11H15N5O4Purezza:99.79%Colore e forma:SolidPeso molecolare:281.279-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormula:C10H13N5O4Purezza:99.97%Colore e forma:SolidPeso molecolare:267.24
