Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(541 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(48 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(180 prodotti)
- Integrina(239 prodotti)
- Chinesina(88 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(275 prodotti)
- PKC(117 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(5 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3827 prodotti di "Ciclo cellulare/Checkpoint"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
TCS 2314
CAS:TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Formula:C28H34N4O6Purezza:98%Colore e forma:SolidPeso molecolare:522.59Trimetrexate glucuronate
CAS:Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.Formula:C25H33N5O10Colore e forma:SolidPeso molecolare:563.564Cdc7-IN-14
CAS:Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.Formula:C18H20N4O2SColore e forma:SolidPeso molecolare:356.44BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Formula:C15H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:288.34CDK4/6-IN-14
CAS:CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.Formula:C24H27ClFN7OColore e forma:SolidPeso molecolare:483.97CI-898 HCl
CAS:CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.Formula:C19H26Cl3N5O3Colore e forma:SolidPeso molecolare:478.8XIE18-6
CAS:XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.Formula:C18H15NO6SPurezza:99.712%Colore e forma:SolidPeso molecolare:373.38BA-1049
CAS:BA-1049 is a selective ROCK2 inhibitor.Formula:C16H21N3O2SColore e forma:SolidPeso molecolare:319.42WF-536 Hydrochloride
CAS:WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.Formula:C14H16ClN3OColore e forma:SolidPeso molecolare:277.755-Ethynyluridine
CAS:5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formula:C11H12N2O6Purezza:99.78%Colore e forma:SolidPeso molecolare:268.22Ref: TM-T36971
5mg49,00€10mg84,00€25mg138,00€50mg236,00€100mg344,00€200mg515,00€1mL*10mM (DMSO)54,00€IRE1α kinase-IN-7
CAS:IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFormula:C28H25F3N6OColore e forma:SolidPeso molecolare:518.53FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Formula:C23H23NO4Colore e forma:SolidPeso molecolare:377.43DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Colore e forma:SolidPeso molecolare:479.47XU1
CAS:XU1（Benzo[c][1,8]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation orFormula:C12H8N2OPurezza:97.81% - 99.59%Colore e forma:SolidPeso molecolare:196.2Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formula:C18H17N7O2SColore e forma:SolidPeso molecolare:395.44BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C16H17N3Colore e forma:SolidPeso molecolare:251.33Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Colore e forma:SolidPeso molecolare:291.71Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Formula:C15H21N5O7SColore e forma:SolidPeso molecolare:415.42BMVC2
CAS:BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.Formula:C28H25I2N3Colore e forma:SolidPeso molecolare:657.33KIF18A-IN-4
CAS:KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.Formula:C22H27N3O3SColore e forma:SolidPeso molecolare:413.53
