Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(112 prodotti)
- CDK(527 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(259 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(284 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(77 prodotti)
Mostrare 10 più sottocategorie
Trovati 3766 prodotti di "Ciclo cellulare/Checkpoint"
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NSC16168
CAS:NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.Formula:C17H15NO9S3Purezza:99.88%Colore e forma:SolidPeso molecolare:473.5Ref: TM-T16351
1mg64,00€5mg137,00€10mg210,00€25mg356,00€50mg525,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)142,00€Cytembena
CAS:Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Formula:C11H8BrNaO4Purezza:99.7%Colore e forma:White PowderPeso molecolare:307.07CHK1-IN-3
CAS:CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Formula:C20H23N9OPurezza:98.78%Colore e forma:SolidPeso molecolare:405.46Ref: TM-T10791
1mg172,00€2mg245,00€5mg393,00€10mg590,00€25mg917,00€50mg1.216,00€100mg1.663,00€200mg2.242,00€1mL*10mM (DMSO)445,00€AGX51
CAS:AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.Formula:C27H29NO4Purezza:97.65%Colore e forma:OilPeso molecolare:431.52Ref: TM-T10268
1mg92,00€5mg216,00€10mg354,00€25mg688,00€50mg905,00€100mg1.169,00€200mg1.586,00€1mL*10mM (DMSO)240,00€Talviraline
CAS:Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFormula:C15H20N2O3S2Purezza:99.88%Colore e forma:SolidPeso molecolare:340.46SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formula:C24H27N5O2Purezza:99.14%Colore e forma:SolidPeso molecolare:417.5Ref: TM-T73475
1mg111,00€5mg264,00€10mg424,00€25mg838,00€50mg1.035,00€100mg1.396,00€1mL*10mM (DMSO)283,00€dCeMM2
CAS:dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Formula:C16H11ClN6OSPurezza:99.68%Colore e forma:SolidPeso molecolare:370.82Ref: TM-T61477
1mg37,00€5mg79,00€10mg119,00€25mg250,00€50mg426,00€100mg633,00€500mg1.349,00€1mL*10mM (DMSO)110,00€EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Formula:C18H14FN5O2SPurezza:98.43%Colore e forma:SolidPeso molecolare:383.4PCSK9-IN-10
CAS:PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.Formula:C18H23N5O4Purezza:99.06%Colore e forma:SoildPeso molecolare:373.41Ref: TM-T72025
2mg42,00€5mg64,00€10mg92,00€25mg178,00€50mg281,00€100mg414,00€200mg585,00€1mL*10mM (DMSO)65,00€Eprociclovir
CAS:Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFormula:C11H15N5O3Purezza:98.50% - 99.86%Colore e forma:SolidPeso molecolare:265.27CMX-521
CAS:CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Formula:C13H17N5O5Purezza:99.57%Colore e forma:SolidPeso molecolare:323.3SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formula:C15H18Br2N4Purezza:99.764% - 99.84%Colore e forma:SolidPeso molecolare:414.14Ref: TM-T10744
1mg645,00€5mg1.614,00€10mg1.985,00€25mg2.300,00€50mg3.022,00€100mg4.085,00€1mL*10mM (DMSO)Prezzo su richiestaAntiviral agent 17
CAS:Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.Formula:C11H14N4O4Purezza:99.89%Colore e forma:SolidPeso molecolare:266.25D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formula:C23H36N6SPurezza:99.65%Colore e forma:SolidPeso molecolare:428.64Ref: TM-T10936
1mg37,00€5mg77,00€10mg126,00€25mg250,00€50mg373,00€100mg547,00€200mg777,00€1mL*10mM (DMSO)85,00€CQ211
CAS:CQ211 is a potent selective RIOK2 inhibitor, Kd 6.1 nM, effectively inhibits cancer cell line proliferation.Formula:C26H22F3N7O2Purezza:97.01% - 98.31%Colore e forma:SolidPeso molecolare:521.49CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formula:C11H8F3N3OPurezza:98.48%Colore e forma:SolidPeso molecolare:255.2Ref: TM-T10740
1mg87,00€5mg216,00€10mg311,00€25mg525,00€50mg707,00€100mg944,00€1mL*10mM (DMSO)240,00€RP-6685
CAS:RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Formula:C22H14F7N5OPurezza:99.65%Colore e forma:SoildPeso molecolare:497.37Ref: TM-T60187
1mg88,00€5mg160,00€10mg230,00€25mg378,00€50mg538,00€100mg755,00€1mL*10mM (DMSO)170,00€SB-747651A Dihydrochloride
CAS:SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Formula:C16H24Cl2N8OPurezza:98.05%Colore e forma:SolidPeso molecolare:415.32Ref: TM-T9652
1mg73,00€5mg155,00€10mg220,00€25mg369,00€50mg525,00€100mg712,00€500mgPrezzo su richiesta1mL*10mM (DMSO)169,00€BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurezza:99.84%Colore e forma:SolidPeso molecolare:260.35Ref: TM-T36964
5mg50,00€10mg85,00€25mg169,00€50mg279,00€100mg487,00€500mg1.035,00€1mL*10mM (DMSO)52,00€hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formula:C21H23FN4OPurezza:99.87%Colore e forma:SolidPeso molecolare:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€
