Trasportatore di membrana/canale ionico

Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain …

Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It …

URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 …

(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads …

GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: …

A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.

Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study …

GLUK5 kainate receptor antagonist

Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that …

PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of …

(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.

NP-1815-PX is a selective P2X4R antagonist with demonstrated anti-inflammatory effects and the capability to alleviate …

α,β-Methylene ATP trisodium, a phosphonate analog of ATP, is a selective P2X agonist that induces …

N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block …

VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of …

CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.

Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].

GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: …

TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate …

Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 …

Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the …

SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM

Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor …

CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of …

(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory …

MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as …

Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, …

Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.

Ouabain octahydrate (Acocantherine) is a cardiac glycoside that inhibits Na(+)/K(+) ATPase. Ouabain octahydrate regulates transcription …

Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of …

Voacangine is a selective and potent antagonist of TRPV1 and TRPM8, and an agonist of …

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human …

Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat …

Indiplon is a short-acting hypnotic with high-affinity allosteric potentiator of GABAA responses that demonstrates preference …

4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side …

DL-Borneol ((endo)-Borneol) is a small molecule extracted from traditional Chinese medicine (TCM). It is an …

Pagoclone (IP456) is a GABA receptor agonist and can be used for studies on the …

N-Arachidonyl-GABA (NA-GABA) is a novel active fatty amino acid related to anandamide (ANA) found in …

Fasoracetam is a modulator of GABA receptor potentially for the treatment of attention deficit hyperactivity …

Bretazenil is a GABAA benzodiazepine site partial agonist. Bretazenil shows an EC50 of 10 nM …

Adinazolam is a triazolobenzodiazepine (TBZD). It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties.

Zuranolone is an agonist of GABAA receptor.

Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.

Radafaxine ((S,S)-Hydroxybupropion), an active metabolite of Bupropion [1] [2], functions as an antidepressant by inhibiting …