Suramin Sodium Salt
CAS: 129-46-4
Ref. TM-T2160
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 515.00 € |
Product Information
- BAY-205, Suramin hexasodium salt, NF-060
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.
Chemical properties
Technical inquiry about: TM-T2160 Suramin Sodium Salt
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