Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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PD-1/PD-L1-IN-10
CAS:<p>PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor activity.Cost-effective and quality-assured.</p>Fórmula:C33H31N3O7Pureza:99.63%Cor e Forma:SolidPeso molecular:581.62YUM70
CAS:<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Fórmula:C21H19ClN2O4Pureza:97.25%Cor e Forma:SolidPeso molecular:398.84PFK-158
CAS:<p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>Fórmula:C18H11F3N2OPureza:95.49% - 99.16%Cor e Forma:SolidPeso molecular:328.29Malachite green oxalate
CAS:<p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>Fórmula:C23H25N2·C2HO4C2H2O4Cor e Forma:Dark Green Crystals With A Metallic LusterPeso molecular:463.51Epothilone A
CAS:<p>Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.</p>Fórmula:C26H39NO6SPureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:493.66ICCB280
CAS:<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Fórmula:C23H18N2O4Pureza:98.04%Cor e Forma:SolidPeso molecular:386.4Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Fórmula:C20H21N3O7SPureza:99.74%Cor e Forma:SolidPeso molecular:447.46Cabozantinib hydrochloride
CAS:<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Fórmula:C28H25ClFN3O5Pureza:99.97%Cor e Forma:SolidPeso molecular:537.96Gefitinib dihydrochloride
CAS:<p>Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.</p>Fórmula:C22H26Cl3FN4O3Cor e Forma:SolidPeso molecular:519.82Brusatol
CAS:<p>Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.</p>Fórmula:C26H32O11Pureza:99.35% - 99.95%Cor e Forma:SolidPeso molecular:520.53Desloratadine
CAS:<p>Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties.</p>Fórmula:C19H19ClN2Pureza:99.79% - >99.99%Cor e Forma:SolidPeso molecular:310.82Sincalide
CAS:<p>Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.</p>Fórmula:C49H62N10O16S3Pureza:98.32%Cor e Forma:SolidPeso molecular:1143.27AZD1208 hydrochloride
CAS:<p>AZD1208 hydrochloride is a highly selective, potent and orally active PIM inhibitor.</p>Fórmula:C21H22ClN3O2SCor e Forma:SolidPeso molecular:415.94Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Fórmula:C10H8O10S3Pureza:99.85%Cor e Forma:SolidPeso molecular:384.36Oxychlororaphine
CAS:<p>Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.</p>Fórmula:C13H9N3OPureza:98.3%Cor e Forma:Green-Yellow SolidPeso molecular:223.23Siramesine hydrochloride
CAS:<p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>Fórmula:C30H32ClFN2OPureza:99.72% - >99.99%Cor e Forma:SolidPeso molecular:491.04Kynurenic acid sodium
CAS:<p>Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.</p>Fórmula:C10H6NNaO3Pureza:99.47%Cor e Forma:SolidPeso molecular:211.15SBI-0640756
CAS:<p>SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.</p>Fórmula:C23H14ClFN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:404.82AMG-337
CAS:<p>AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).</p>Fórmula:C23H22FN7O3Pureza:99.26% - 99.9%Cor e Forma:SolidPeso molecular:463.46Mycophenolic acid sodium
CAS:<p>Mycophenolic acid sodium inhibits IMPDH with EC50 of 0.24 μM, has antiviral, immunosuppressive, antiangiogenic, and antitumor properties.</p>Fórmula:C17H19NaO6Cor e Forma:SolidPeso molecular:342.323Perifosine
CAS:<p>Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.</p>Fórmula:C25H52NO4PPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:461.66Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Fórmula:C21H24O6Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:372.41RA375
CAS:<p>RA375 inhibits RPN13, enhances UPR, ROS, apoptosis, and is 10x more potent against cancer than RA190 due to nitro rings and chloroacetamide.</p>Fórmula:C30H25ClN4O7Pureza:99.56%Cor e Forma:SolidPeso molecular:588.99L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Fórmula:C8H19ClN2O3SCor e Forma:SolidPeso molecular:258.77BIX01294 (hydrochloride hydrate)
CAS:<p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>Fórmula:C28H43Cl3N6O3Cor e Forma:SolidPeso molecular:618.04Tandutinib hydrochloride
CAS:<p>Tandutinib hydrochloride: FLT3 inhibitor (IC50 0.22 μM), targets c-Kit, PDGFR, treats AML, crosses blood-brain barrier.</p>Fórmula:C31H43ClN6O4Cor e Forma:SolidPeso molecular:599.16Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C19H32N2O4Pureza:99.26%Cor e Forma:CoaPeso molecular:352.47Anagrelide hydrochloride
CAS:<p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>Fórmula:C10H7Cl2N3O·HClPureza:99.58%Cor e Forma:Off-White PowderPeso molecular:292.55Chrysosplenol D
CAS:<p>Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.</p>Fórmula:C18H16O8Pureza:97.87% - 99.98%Cor e Forma:SolidPeso molecular:360.31Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Fórmula:C13H16N2O2Pureza:98% - 99.89%Cor e Forma:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28SIRT7 inhibitor 97491
CAS:<p>SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.</p>Fórmula:C15H12ClN3OPureza:99.79%Cor e Forma:SolidPeso molecular:285.73Crebanine
CAS:<p>Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.</p>Fórmula:C20H21NO4Pureza:99.17% - 99.77%Cor e Forma:SolidPeso molecular:339.39Pectolinarin
CAS:<p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>Fórmula:C29H34O15Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:622.57Adaphostin
CAS:<p>Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.</p>Fórmula:C24H27NO4Pureza:98.29%Cor e Forma:SolidPeso molecular:393.48RIPGBM
CAS:<p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>Fórmula:C26H21FN2O3Pureza:99.45%Cor e Forma:SolidPeso molecular:428.45Fipronil
CAS:<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:Solid PowderPeso molecular:437.15MS7972
CAS:<p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>Fórmula:C14H13NO2Pureza:99.78%Cor e Forma:SolidPeso molecular:227.26Cystamine dihydrochloride
CAS:<p>Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.</p>Fórmula:C4H14Cl2N2S2Pureza:98.91% - 99.81%Cor e Forma:White PowderPeso molecular:225.19IMT1
CAS:<p>IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.</p>Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4PS47
CAS:<p>PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.</p>Fórmula:C17H15ClO2Pureza:99.09%Cor e Forma:SolidPeso molecular:286.75AZD0156
CAS:<p>AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.</p>Fórmula:C26H31N5O3Pureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:461.56Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Fórmula:C19H26O7Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:366.41Ketorolac hemicalcium
CAS:<p>Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.</p>Fórmula:C30H24CaN2O6Cor e Forma:SolidPeso molecular:548.608Bigelovin
CAS:<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Fórmula:C17H20O5Pureza:99.61% - 99.72%Cor e Forma:SolidPeso molecular:304.34Difurazon hydrochloride
CAS:<p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>Fórmula:C14H13ClN6O6Pureza:98.51%Cor e Forma:SolidPeso molecular:396.74Ginsenoside Rg1
CAS:<p>Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).</p>Fórmula:C42H72O14Pureza:99% - 99.74%Cor e Forma:White Crystalline PowderPeso molecular:801.01LY2409881 trihydrochloride
CAS:<p>LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.</p>Fórmula:C24H32Cl4N6OSPureza:≥95%Cor e Forma:SolidPeso molecular:594.43RX-3117
CAS:<p>RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog.</p>Fórmula:C10H12FN3O4Pureza:97.46%Cor e Forma:SolidPeso molecular:257.22Fosbretabulin Disodium
CAS:<p>Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).</p>Fórmula:C18H19O8P·2NaPureza:97.43% - 99.96%Cor e Forma:White SolidPeso molecular:440.29
