Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5593 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Eriocitrin
CAS:<p>Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.</p>Fórmula:C27H32O15Pureza:98.41% - 99.11%Cor e Forma:SolidPeso molecular:596.53Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Fórmula:C26H39Cl2N5O5SPureza:99.64% - 99.78%Cor e Forma:SolidPeso molecular:604.59NSC 23766 trihydrochloride
CAS:<p>NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.</p>Fórmula:C24H35N7·3HClPureza:96.48% - 99.54%Cor e Forma:SolidPeso molecular:530.96Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Cor e Forma:White Crystalline SolidPeso molecular:377.32Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Cor e Forma:SolidPeso molecular:418.3Flavokawain A
CAS:<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Fórmula:C18H18O5Pureza:97.1% - 99.72%Cor e Forma:SolidPeso molecular:314.332Nivolumab
CAS:<p>Nivolumab is a monoclonal antibody, a humanized IgG4 antibody to PD-1. Nivolumab has antitumor activity. Cost-effective and quality-assured.</p>Pureza:98% - 98%Cor e Forma:LiquidPeso molecular:146 kDaGanoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Cor e Forma:SolidPeso molecular:514.65EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.4Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Cor e Forma:SolidPeso molecular:338.35NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Cor e Forma:SolidPeso molecular:319.313-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Cor e Forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Fórmula:C18H13ClF6N2O3Pureza:99.80%Cor e Forma:SolidPeso molecular:454.75TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:SolidPeso molecular:428.82Solamargine
CAS:<p>Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.</p>Fórmula:C45H73NO15Pureza:99.17% - 99.96%Cor e Forma:SolidPeso molecular:868.06Garcinol
CAS:<p>Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).</p>Fórmula:C38H50O6Pureza:98.59%Cor e Forma:SolidPeso molecular:602.8Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4Actein
CAS:<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Fórmula:C37H56O11Pureza:≥98%Cor e Forma:Brown PowderPeso molecular:676.83UCF 101
CAS:<p>UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.</p>Fórmula:C27H17N3O5SPureza:99.64%Cor e Forma:SolidPeso molecular:495.51PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Cor e Forma:SolidPeso molecular:319.36Liproxstatin-1
CAS:<p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Cor e Forma:SolidPeso molecular:340.85Gomisin N
CAS:<p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>Fórmula:C23H28O6Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:400.46PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Fórmula:C18H39NO3Pureza:99.81%Cor e Forma:SolidPeso molecular:317.51AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Fórmula:C18H20N8O2Pureza:99.03% - 99.85%Cor e Forma:SolidPeso molecular:380.4Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Cor e Forma:Grayish-Yellow PowderPeso molecular:541.08Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Fórmula:C29H36O15Pureza:97.46% - 99.55%Cor e Forma:SolidPeso molecular:624.59Cabozantinib S-malate
CAS:<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Fórmula:C32H30FN3O10Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:635.59PF-3758309 hydrochloride
CAS:<p>PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (</p>Fórmula:C25H31ClN8OSPureza:98.83% - >99.99%Cor e Forma:SolidPeso molecular:527.08CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Fórmula:C17H12F3NO3SPureza:99.02%Cor e Forma:SolidPeso molecular:367.34Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Cor e Forma:White Crystal Or PowderPeso molecular:182.17EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Cor e Forma:SolidPeso molecular:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.27McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:925.16Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Cor e Forma:SolidPeso molecular:246.35Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Fórmula:C23H28O13Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:512.46Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Fórmula:C9H6OS3Pureza:98.05% - 98.41%Cor e Forma:SolidPeso molecular:226.34NVP-HSP990
CAS:<p>NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).</p>Fórmula:C20H18FN5O2Pureza:98.03% - 99.32%Cor e Forma:SolidPeso molecular:379.39Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:610.66Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61ONC212
CAS:<p>ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.</p>Fórmula:C24H23F3N4OPureza:99.79%Cor e Forma:SolidPeso molecular:440.46Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Cor e Forma:SolidPeso molecular:409.261R,3S-RSL 3
CAS:<p>1R,3S-RSL 3 is a harmala alkaloid.</p>Fórmula:C23H21ClN2O5Pureza:99.51%Cor e Forma:SolidPeso molecular:440.88Amcasertib
CAS:<p>Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.</p>Fórmula:C31H33N5O2SPureza:97.56% - >99.99%Cor e Forma:SolidPeso molecular:539.69Paroxetine
CAS:<p>Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.</p>Fórmula:C19H20FNO3Pureza:98.89% - 99.45%Cor e Forma:White To Off-White PowderPeso molecular:329.37Parcetasal
CAS:<p>Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.</p>Fórmula:C17H15NO5Pureza:99.07%Cor e Forma:SolidPeso molecular:313.3Romidepsin
CAS:<p>Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.</p>Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Cor e Forma:SolidPeso molecular:540.7PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:188.31
