Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(91 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
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Dequalinium chloride
CAS:Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.
Fórmula:C30H40Cl2N4Pureza:99.79% - 99.9%Cor e Forma:SolidPeso molecular:527.59ACHP
CAS:ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β.Fórmula:C21H24N4O2Pureza:98.77%Cor e Forma:SolidPeso molecular:364.44Ref: TM-T22021
1mg50,00€5mg101,00€10mg150,00€25mg241,00€50mg353,00€100mg602,00€200mg982,00€500mg1.963,00€Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Fórmula:C21H27NO3Pureza:99.02%Cor e Forma:SolidPeso molecular:341.44Human sHLA-G(soluble human leucocyte antigen G) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human sHLA-G. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human sHLA-G. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human sHLA-G, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human sHLA-G in the samples is then determined by comparing the OD of the samples to the standard curve.Sodium butanoate
CAS:Sodium butanoate (Sodium Butyrate) is the sodium salt of butyrate with potential antineoplastic activity.
Fórmula:C4H7NaO2Pureza:98.02% - 99.79%Cor e Forma:White PowderPeso molecular:110.09AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56Ref: TM-T14381
1mg70,00€5mg152,00€10mg236,00€25mg432,00€50mg647,00€100mg964,00€1mL*10mM (DMSO)166,00€TYA-018
CAS:TYA-018 is an HDAC6 inhibitor with cardioprotective effects and is used in the study of dilated heart disease and heart failure.Fórmula:C15H13ClF2N4O3S2Pureza:98.64%Cor e Forma:SolidPeso molecular:434.87Ac-FLTD-CMK
CAS:Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.
Fórmula:C26H37ClN4O8Pureza:95.17%Cor e Forma:SolidPeso molecular:569.05Estradiol benzoate
CAS:Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility in females.Fórmula:C25H28O3Pureza:99.7% - 99.93%Cor e Forma:SolidPeso molecular:376.49Onvatilimab
CAS:Onvatilimab (JNJ-61610588) is a human IgG1 κ monoclonal antibody with antitumor effects for advanced head and neck cancers.
Pureza:98.11% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:144.52 kDaTiratricol
CAS:Tiratricol, a thyroid hormone metabolite for hyperlipidemia and obesity, studied in Allan-Herndon-Dudley Syndrome treatment.Fórmula:C14H9I3O4Pureza:98.77% - 99.16%Cor e Forma:SolidPeso molecular:621.93Nebivolol hydrochloride
CAS:Nebivolol hydrochloride is a beta-1 blocker and vasodilator treating hypertension and heart failure in the elderly.Fórmula:C22H25F2NO4·HClPureza:99.77% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:441.90Diethylstilbestrol
CAS:Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.Fórmula:C18H20O2Pureza:97.77% - 98.78%Cor e Forma:White Crystalline Powder Physical Description Odorless Tasteless White Crystalline Powder (Ntp 1992)Peso molecular:268.35Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:506.03Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Fórmula:C19H24ClNO4Pureza:99.43%Cor e Forma:SolidPeso molecular:365.85(R)-CR8
CAS:(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
Fórmula:C24H29N7OPureza:98.41%Cor e Forma:SolidPeso molecular:431.53Umbelliferone
CAS:Umbelliferone, aka 7-Hydroxycoumarin, in anise and many plants, is a phytoalexin with antioxidant effects.Fórmula:C9H6O3Pureza:98.65% - 99.64%Cor e Forma:Off-White Crystalline PowderPeso molecular:162.14Cetrimonium bromide
CAS:Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.
Fórmula:C19H42BrNPureza:≥95%Cor e Forma:SolidPeso molecular:364.46Vincristine sulfate
CAS:Vincristine sulfate is a natural alkaloid. Vincristine sulfate is used as a microtubule destabilizer for the study of tumors. Cost-effective, quality assurance.Fórmula:C46H58N4O14SPureza:98% - 99.94%Cor e Forma:White Crystalline PowderPeso molecular:923.04Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Fórmula:C31H35N2NaO11Pureza:99% - 99.51%Cor e Forma:SolidPeso molecular:634.61Vitamin K4
CAS:Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4.Fórmula:C15H14O4Pureza:99.84%Cor e Forma:White Crystalline PowderPeso molecular:258.27AP20187
CAS:AP20187: Cell-permeable ligand dimerizing FKBP fusion proteins for signaling and gene expression control.Fórmula:C82H107N5O20Pureza:99.05% - 99.80%Cor e Forma:SolidPeso molecular:1482.75Benzenebutanoic acid, sodium salt (1:1)
CAS:Fórmula:C10H12NaO2Pureza:%Cor e Forma:SolidPeso molecular:187.1909Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41Tetrahydroxyquinone
CAS:Tetrahydroxyquinone (Tetroquinone) is a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle.Fórmula:C6H4O6Pureza:98.15%Cor e Forma:Penetrating Odor Black SolidPeso molecular:172.09Ref: IN-DA006YB9
1gA consultar1mg50,00€5mg52,00€10mg68,00€25mg129,00€50mg150,00€100mg163,00€250mg555,00€5-Fluorouridine
CAS:5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.Fórmula:C9H11FN2O6Pureza:99.76% - 99.85%Cor e Forma:White PowderPeso molecular:262.19Mouse CASP3(Caspase 3) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CASP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CASP3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse CASP3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse CASP3 in the samples is then determined by comparing the OD of the samples to the standard curve.BT2
CAS:BT2 inhibits BDK (IC50: 3.19 μM) & Mcl-1 (Ki: 59 μM), causing helix shift & BDK detachment from BCKDC.
Fórmula:C9H4Cl2O2SPureza:99.27% - 99.86%Cor e Forma:SolidPeso molecular:247.1Rat CASP3(Caspase 3) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CASP3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CASP3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat CASP3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat CASP3 in the samples is then determined by comparing the OD of the samples to the standard curve.Human RANKL(Receptor Activator of Nuclear factor-kB Ligand) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RANKL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RANKL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human RANKL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human RANKL in the samples is then determined by comparing the OD of the samples to the standard curve.Gboxin
CAS:Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.Fórmula:C22H33ClN2O2Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:392.96Ref: TM-T15373
1mg42,00€2mg55,00€5mg88,00€10mg126,00€25mg245,00€50mg385,00€100mg612,00€200mg850,00€1mL*10mM (DMSO)87,00€Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Cor e Forma:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Penfluridol
CAS:Penfluridol (TLP-607) is a highly potent antipsychotic.Fórmula:C28H27ClF5NOPureza:98.9% - 99.87%Cor e Forma:Off-White To White Crystalline PowderPeso molecular:523.97Ascorbyl palmitate
CAS:Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C.
Fórmula:C22H38O7Pureza:99.52%Cor e Forma:White Or Yellowish White Powder White Or Yellowish-White Powder With A Citrus-Like OdourPeso molecular:414.53Human sRANkL(Soluble Receptor Activator Of Nuclear Factor κ B Ligand) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human sRANkL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human sRANkL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human sRANkL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human sRANkL in the samples is then determined by comparing the OD of the samples to the standard curve.Dipyridamole
CAS:Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.Fórmula:C24H40N8O4Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:504.63Trifluridine
CAS:Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.Fórmula:C10H11F3N2O5Pureza:99.39% - 99.82%Cor e Forma:White Crystalline PowderPeso molecular:296.2Human GZMB(Granzyme B) Microsample ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GZMB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GZMB. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human GZMB, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human GZMB in the samples is then determined by comparing the OD of the samples to the standard curve.Letolizumab
CAS:Letolizumab (BMS-986004) is a dimeric antibody that targets CD40L.Pureza:98.8% (SDS-PAGE); 99.2% (SEC-HPLC) - 98.8% (SDS-PAGE); 99.2% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:38.99 kDaCinchonine
CAS:Cinchonine (LA40221), a potent amide local anesthetic for surface use, is toxic and limited to spinal anesthesia.Fórmula:C19H22N2OPureza:99.45%Cor e Forma:White Or Almost White Solid PowderPeso molecular:294.39Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Farudodstat
CAS:Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH with antitumor activity. It has the potential to be a first-in-class candidate in AML.Fórmula:C19H14F2N2O3Pureza:98.36%Cor e Forma:SolidPeso molecular:356.32Tea polyphenol
CAS:Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.Fórmula:C17H19N3OPureza:98%Cor e Forma:Yelloish Green Free Flowing PowderPeso molecular:281.36MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Fórmula:C20H19N7OPureza:99.23%Cor e Forma:SolidPeso molecular:373.41Ref: TM-T12134
1mg71,00€5mg152,00€10mg222,00€25mg358,00€50mg512,00€100mg707,00€200mg973,00€500mg1.431,00€9-cis-Retinoic Acid
CAS:9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist and can be used to study advanced tumors.Fórmula:C20H28O2Pureza:98.32% - 99.90%Cor e Forma:SolidPeso molecular:300.44PF-4878691
CAS:PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.Fórmula:C17H23N5O2SPureza:98.43%Cor e Forma:SolidPeso molecular:361.46Ref: TM-T16506
1mg46,00€5mg137,00€10mg222,00€25mg485,00€50mg802,00€100mg1.305,00€1mL*10mM (DMSO)150,00€Mirodenafil
CAS:Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Fórmula:C26H37N5O5SPureza:99.89%Cor e Forma:SolidPeso molecular:531.67Ref: TM-T16079
2mg35,00€5mg52,00€10mg79,00€25mg134,00€50mg210,00€100mg338,00€200mg497,00€1mL*10mM (DMSO)60,00€MV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Fórmula:C33H44N4O5Pureza:99.86%Cor e Forma:SolidPeso molecular:576.73Ref: TM-T16163
2mg44,00€5mg67,00€10mg112,00€25mg187,00€50mg280,00€100mg396,00€200mg522,00€1mL*10mM (DMSO)86,00€APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Fórmula:C22H14FN5Pureza:98.73%Cor e Forma:SolidPeso molecular:367.38Ref: TM-T10352
1mg40,00€2mg52,00€5mg75,00€10mg96,00€25mg170,00€50mg255,00€100mg371,00€1mL*10mM (DMSO)84,00€
