Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(127 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
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Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Fórmula:C19H26ClN7OPureza:99.73%Cor e Forma:SolidPeso molecular:403.91Ref: TM-T22260
2mg39,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg173,00€50mg269,00€100mg389,00€200mg555,00€Apomine
CAS:Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。Fórmula:C28H52O7P2Pureza:>99.99%Cor e Forma:SolidPeso molecular:562.66TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Cor e Forma:White Solid PowderPeso molecular:166.22Ginsenoside Rh2
CAS:Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.Fórmula:C36H62O8Pureza:99.20% - 99.76%Cor e Forma:White PowderPeso molecular:622.87Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Fórmula:C42H72O13Pureza:99.04% - 99.3%Cor e Forma:SolidPeso molecular:785.01Ref: TM-T3916
1mg34,00€5mg65,00€1mL*10mM (DMSO)92,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€HA14-1
CAS:HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).Fórmula:C17H17BrN2O5Pureza:95.07% - 98%Cor e Forma:SolidPeso molecular:409.23LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:500.63Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Fórmula:C23H20N6OPureza:99% - 99.21%Cor e Forma:SolidPeso molecular:396.44AG1024
CAS:AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Fórmula:C14H13BrN2OPureza:98% - 99.37%Cor e Forma:SolidPeso molecular:305.17Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Fórmula:C20H15Cl3N2OSPureza:99.483%Cor e Forma:SolidPeso molecular:437.77Ref: TM-T50005
5mg55,00€10mg78,00€1mL*10mM (DMSO)79,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€Rigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Fórmula:C21H25NO8SPureza:99.53%Cor e Forma:SolidPeso molecular:451.49PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Cor e Forma:SolidPeso molecular:348.36ML311
CAS:ML311 is a selective inhibitor of the Mcl-1/Bim interaction.Fórmula:C23H24F3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:415.45Asiaticoside
CAS:Asiaticoside, in Centella asiatica, may treat wounds/burns.Fórmula:C48H78O19Pureza:98% - 99.96%Cor e Forma:PowderPeso molecular:959.12SC66
CAS:SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).
Fórmula:C18H16N2OPureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:276.33Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Fórmula:C20H20Cl2N6OPureza:97.33% - 98.92%Cor e Forma:SolidPeso molecular:431.318NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.
Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12Idasanutlin
CAS:Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).Fórmula:C31H29Cl2F2N3O4Pureza:99.13% - 99.88%Cor e Forma:SolidPeso molecular:616.48Ref: TM-T6254
2mg38,00€5mg57,00€1mL*10mM (DMSO)79,00€10mg90,00€25mg150,00€50mg215,00€100mg356,00€500mg837,00€CPTH2
CAS:CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.Fórmula:C14H14ClN3SPureza:99.81%Cor e Forma:SolidPeso molecular:291.8ZMC1
CAS:NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Fórmula:C11H14N4SPureza:98.97% - 99.76%Cor e Forma:SolidPeso molecular:234.32RAD51 Inhibitor B02
CAS:RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.Fórmula:C22H17N3OPureza:99.72% - 99.89%Cor e Forma:SolidPeso molecular:339.39Bendamustine
CAS:Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic LeukemiaFórmula:C16H21Cl2N3O2Pureza:99.99% - ≥98%Cor e Forma:SolidPeso molecular:358.26Ref: TM-T8380
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)89,00€10mg113,00€25mg245,00€50mg385,00€100mg575,00€500mg1.234,00€Sertaconazole nitrate
CAS:Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Cor e Forma:SolidPeso molecular:500.78Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Cor e Forma:SolidPeso molecular:512.56Grape Seed Extract
CAS:Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.Fórmula:C32H30O11Pureza:98%Cor e Forma:SolidPeso molecular:590.581CVT-11127
CAS:CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.Fórmula:C25H23Cl2N5O3Pureza:98.32%Cor e Forma:SolidPeso molecular:512.39N-Ethylmaleimide
CAS:N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.Fórmula:C6H7NO2Pureza:99.50%Cor e Forma:White SolidPeso molecular:125.13OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Fórmula:C31H43N3O8Pureza:98.24% - 99.83%Cor e Forma:Dark Purple SolidPeso molecular:585.692-tert-Butyl-1,4-benzoquinone
CAS:TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.Fórmula:C10H12O2Pureza:97.19%Cor e Forma:SolidPeso molecular:164.2Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Fórmula:C29H32N6O4SPureza:98% - 99.42%Cor e Forma:SolidPeso molecular:560.67Ref: TM-T2066
5mg58,00€1mL*10mM (DMSO)71,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€Caudatin
CAS:Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Fórmula:C28H42O7Pureza:98.83% - 99.84%Cor e Forma:SolidPeso molecular:490.63Ref: TM-T3150
1mg52,00€5mg100,00€1mL*10mM (DMSO)119,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Fórmula:C26H44NNaO6SPureza:98.23% - 99.56%Cor e Forma:White To Off-White PowderPeso molecular:521.68GSK-J4
CAS:GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Fórmula:C24H27N5O2Pureza:98.24% - 99.98%Cor e Forma:SolidPeso molecular:417.5Ref: TM-T3100
2mg52,00€5mg86,00€10mg122,00€1mL*10mM (DMSO)134,00€25mg215,00€50mg345,00€100mg523,00€200mg663,00€Angelicin
CAS:Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Fórmula:C11H6O3Pureza:99.86% - 99.89%Cor e Forma:White SolidPeso molecular:186.16Fimasartan
CAS:Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.Fórmula:C27H31N7OSPureza:98.96%Cor e Forma:SolidPeso molecular:501.65Lenalidomide hemihydrate
CAS:Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.Fórmula:C13H13N3O3H2OPureza:96.22%Cor e Forma:SolidPeso molecular:268.28ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Cor e Forma:SolidPeso molecular:539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Fórmula:C24H22O6Pureza:98.40% - 98.59%Cor e Forma:SolidPeso molecular:406.43BI-6C9
CAS:BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.Fórmula:C23H25N3O4S2Pureza:98.39%Cor e Forma:SolidPeso molecular:471.59Ref: TM-T5827
1mg66,00€2mg95,00€5mg144,00€1mL*10mM (DMSO)150,00€10mg210,00€25mg376,00€50mg557,00€100mg782,00€200mg1.035,00€Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Fórmula:C18H21N5O2Pureza:99.63%Cor e Forma:SolidPeso molecular:339.39Ref: TM-T6192
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg60,00€25mg81,00€50mg92,00€100mg129,00€200mg178,00€Takinib
CAS:Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).Fórmula:C18H18N4O2Pureza:98.29% - 99.35%Cor e Forma:SolidPeso molecular:322.36ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Cor e Forma:SolidPeso molecular:475.32Ref: TM-T8375
1mg34,00€2mg49,00€5mg82,00€1mL*10mM (DMSO)86,00€10mg133,00€25mg234,00€50mg393,00€100mg528,00€UMI-77
CAS:UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.Fórmula:C18H14BrNO5S2Pureza:96% - 99.57%Cor e Forma:SolidPeso molecular:468.34Ref: TM-T6034
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)86,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€200mg692,00€500mg1.035,00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFórmula:C49H58FN9O7SPureza:97.54% - 98.15%Cor e Forma:SolidPeso molecular:936.1[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Fórmula:C19H28O3Pureza:97.01%Cor e Forma:SolidPeso molecular:304.42Ref: TM-T5430
1mg90,00€5mg197,00€1mL*10mM (DMSO)219,00€10mg339,00€25mg560,00€50mg793,00€100mg1.063,00€R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Fórmula:C16H8ClF3N4SPureza:98.64% - 99.8%Cor e Forma:SolidPeso molecular:380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)71,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Fórmula:C20H22O7Pureza:99.88%Cor e Forma:SolidPeso molecular:374.38Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Fórmula:C8H18N3O8PPureza:99.44%Cor e Forma:SolidPeso molecular:315.22
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