Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5593 produtos de "Apoptose"
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Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Cor e Forma:SolidPeso molecular:384.27iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Cor e Forma:SolidPeso molecular:394.53Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Fórmula:C32H48N4O8·HClPureza:99.94%Cor e Forma:SolidPeso molecular:653.21EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.4IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Fórmula:C26H23FN8OPureza:99.31%Cor e Forma:SolidPeso molecular:482.51NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Cor e Forma:SolidPeso molecular:319.31CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Fórmula:C18H13ClF6N2O3Pureza:99.80%Cor e Forma:SolidPeso molecular:454.75Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Cor e Forma:SolidPeso molecular:1046.18Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Cor e Forma:Grayish-Yellow PowderPeso molecular:541.08Olsalazine
CAS:<p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>Fórmula:C14H10N2O6Pureza:99.31%Cor e Forma:SolidPeso molecular:302.24McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:925.16TASIN-1
CAS:<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Fórmula:C18H28N2O3SPureza:99.86%Cor e Forma:SolidPeso molecular:352.49Iproniazid
CAS:<p>Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.</p>Fórmula:C9H13N3OPureza:98%Cor e Forma:SolidPeso molecular:179.22CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Fórmula:C15H20ClN5O4Pureza:99.1%Cor e Forma:Off-White To Light Yellow SolidPeso molecular:369.8Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:610.66Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Cor e Forma:SolidPeso molecular:409.26Paroxetine
CAS:<p>Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.</p>Fórmula:C19H20FNO3Pureza:98.89% - 99.45%Cor e Forma:White To Off-White PowderPeso molecular:329.37Romidepsin
CAS:<p>Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.</p>Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Cor e Forma:SolidPeso molecular:540.7PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:188.31L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Fórmula:C13H13ClN4OSPureza:98.6% - 99.13%Cor e Forma:SolidPeso molecular:308.79Saquinavir
CAS:<p>Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.</p>Fórmula:C38H50N6O5Pureza:99.50% - >99.99%Cor e Forma:SolidPeso molecular:670.84Tenilsetam
CAS:<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Fórmula:C8H10N2OSPureza:99.52%Cor e Forma:SolidPeso molecular:182.244-IBP
CAS:<p>4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .</p>Fórmula:C19H21IN2OPureza:98.99%Cor e Forma:SolidPeso molecular:420.29Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Cor e Forma:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46RH01687
CAS:<p>RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.</p>Fórmula:C12H9ClN6O2SPureza:97.93%Cor e Forma:SolidPeso molecular:336.76Clodronic acid disodium salt
CAS:<p>Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.</p>Fórmula:CH4Cl2O6P0·2NaPureza:>99.99% - ≥98%Cor e Forma:White SolidPeso molecular:288.86Sodium benzoate
CAS:<p>Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.</p>Fórmula:C7H5NaO2Pureza:99.72%Cor e Forma:White Solid CrystallinePeso molecular:144.10HX 531
CAS:<p>HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.</p>Fórmula:C29H29N3O4Pureza:98.59% - 99.86%Cor e Forma:SolidPeso molecular:483.56Isobutylparaben
CAS:<p>Isobutylparaben is a preservative and preservative insecticide.</p>Fórmula:C11H14O3Pureza:99.36%Cor e Forma:White CreamPeso molecular:194.23Quinocetone
CAS:<p>Quinocetone is an animal growth promoter and potential anti-tumor activity.</p>Fórmula:C18H14N2O3Pureza:98.06%Cor e Forma:SolidPeso molecular:306.32Dantrolene sodium hemiheptahydrate
CAS:<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Fórmula:C14H9N4NaO5·5H2OPureza:99.72%Cor e Forma:Orange PowderPeso molecular:399.29GYY4137
CAS:<p>GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with antihypertensive, anti-inflammatory and anticancer activity.</p>Fórmula:C11H16NO2PS2·C4H9NOPureza:95.54% - 99.97%Cor e Forma:SolidPeso molecular:376.47DIM-C-pPhCO2Me
CAS:<p>DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.</p>Fórmula:C25H20N2O2Pureza:99.55% - 99.86%Cor e Forma:SolidPeso molecular:380.44Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Fórmula:C8H11N5O2Pureza:99.54%Cor e Forma:SolidPeso molecular:209.212-HBA
CAS:<p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>Fórmula:C17H14O3Pureza:99.76%Cor e Forma:SolidPeso molecular:266.293,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Fórmula:C9H4Cl2O2Pureza:97.94%Cor e Forma:SolidPeso molecular:215.03Thalidomide-NH-CH2-COOH TFA
CAS:<p>2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.</p>Fórmula:C17H14F3N3O8Pureza:95.00%Cor e Forma:SolidPeso molecular:445.3036ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Cor e Forma:SolidPeso molecular:533.59BMS202 hydrochloride (1675203-84-5(free base))
CAS:<p>BMS202 hydrochloride (1675203-84-5) is a potent PD-1/PD-L1 inhibitor (IC50: 18 nM) that promotes PD-L1 dimerization, blocking PD1 binding.</p>Fórmula:C25H30ClN3O3Pureza:98.29% - 99.47%Cor e Forma:SolidPeso molecular:455.97Hexamethylene bisacetamide
CAS:<p>Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.</p>Fórmula:C10H20N2O2Pureza:99.94%Cor e Forma:White FlakesPeso molecular:200.28PDL-1 cpd 10
CAS:<p>PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.</p>Fórmula:C21H23N5O2Pureza:97.08%Cor e Forma:SolidPeso molecular:377.44Sinapinic Acid
CAS:<p>Sinapinic Acid (Synapoic acid) is a phenolic isolated from the roots of Hydnophytum formicarumJack. It is an HDAC inhibitor and also inhibits ACE-I activity.</p>Fórmula:C11H12O5Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:224.21Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Fórmula:C14H11N3O3SPureza:98% - 99.91%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:301.32Rhapontin
CAS:<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Fórmula:C21H24O9Pureza:99% - 99.91%Cor e Forma:Light YellowPeso molecular:420.41Perillyl alcohol
CAS:<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Fórmula:C10H16OPureza:97.36%Cor e Forma:SolidPeso molecular:152.23Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Fórmula:C30H48O5Pureza:98.93%Cor e Forma:SolidPeso molecular:488.7Z-DEVD-FMK
CAS:<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Cor e Forma:SolidPeso molecular:668.66
