Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(127 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
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Lexibulin
CAS:Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).Fórmula:C24H30N6O2Pureza:98.87%Cor e Forma:SolidPeso molecular:434.53Ref: TM-T2090
1mg39,00€5mg84,00€10mg114,00€25mg222,00€50mg334,00€100mg494,00€200mg702,00€1mL*10mM (DMSO)93,00€Cucurbitacin IIb
CAS:Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.Fórmula:C30H48O7Pureza:98.66% - >99.99%Cor e Forma:SolidPeso molecular:520.7Ref: TM-T4S1469
1mg96,00€5mg208,00€10mg359,00€25mg592,00€50mg837,00€100mg1.121,00€1mL*10mM (DMSO)240,00€Poncirin
CAS:Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.Fórmula:C28H34O14Pureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:594.56Entinostat
CAS:Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H20N4O3Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:376.41Ligustilide
CAS:3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.Fórmula:C12H14O2Pureza:96.03% - 99.97%Cor e Forma:Yellow Brown PowderPeso molecular:190.24MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Fórmula:C20H37N3O4Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:383.53Dioscin
CAS:Dioscin (Collettiside III) is a saponin with antitumor activities.Fórmula:C45H72O16Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:869.04Ref: TM-T6473
5mg34,00€10mg42,00€25mg58,00€50mg81,00€100mg105,00€200mg152,00€500mg245,00€1mL*10mM (DMSO)52,00€JIB-04
CAS:JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.Fórmula:C17H13ClN4Pureza:98.02% - 98.87%Cor e Forma:SolidPeso molecular:308.76Ref: TM-T1868
2mg34,00€5mg48,00€10mg71,00€25mg94,00€50mg155,00€100mg259,00€200mg425,00€500mg687,00€1mL*10mM (DMSO)78,00€Tebufenozide
CAS:Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.Fórmula:C22H28N2O2Pureza:98%Cor e Forma:SolidPeso molecular:352.47Y-320
CAS:Y-320 is a new phenylpyrazoleanilide immunomodulator.Fórmula:C27H29ClN6O2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:505.01Ref: TM-T1846
2mg34,00€5mg49,00€10mg71,00€25mg137,00€50mg224,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)50,00€PIK-75 hydrochloride
CAS:PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.Fórmula:C16H14BrN5O4S·HClPureza:97.82%Cor e Forma:SolidPeso molecular:488.745-Aminolevulinic acid hydrochloride
CAS:5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Fórmula:C5H10ClNO3Pureza:98% - 99.97%Cor e Forma:White To Pale Yellow Crystals OrPeso molecular:167.59Pulsatilla saponin D
CAS:Pulsatilla saponin D (Hederacolchiside A) may prevent cancer, hindering cancer cell growth through cell cycle arrest and apoptosis.Fórmula:C47H76O17Pureza:99.55%Cor e Forma:SolidPeso molecular:913.1Fludarabine Phosphate
CAS:Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Cor e Forma:SolidPeso molecular:365.21Ref: TM-T6501
5mg35,00€10mg54,00€25mg87,00€50mg109,00€100mg133,00€200mg180,00€500mg303,00€1mL*10mM (DMSO)52,00€L-Theanine
CAS:L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.Fórmula:C7H14N2O3Pureza:99.31% - 99.38%Cor e Forma:White Crystals From Ethanol + Water White Crystalline SolidPeso molecular:174.20Tomatine
CAS:Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Fórmula:C50H83NO21Pureza:98.42% - 99.94%Cor e Forma:White To Light YellowPeso molecular:1034.19Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Cor e Forma:SolidPeso molecular:507.56Glaucocalyxin A
CAS:Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.
Fórmula:C20H28O4Pureza:99.55% - 99.80%Cor e Forma:SolidPeso molecular:332.43Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Fórmula:C18H15N5OPureza:97.03%Cor e Forma:SolidPeso molecular:317.34BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Cor e Forma:SolidPeso molecular:464.56Salidroside
CAS:Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Fórmula:C14H20O7Pureza:97.81%Cor e Forma:Red-Brown Fine PowderPeso molecular:300.30Ref: TM-T2717
2mg34,00€5mg50,00€10mg81,00€25mg130,00€50mg178,00€100mg268,00€200mg408,00€1mL*10mM (DMSO)55,00€BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Fórmula:C28H39N7O3Pureza:98% - 99.88%Cor e Forma:SolidPeso molecular:521.65Ref: TM-T6173
1mg43,00€2mg56,00€5mg93,00€10mg98,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)92,00€Pyroxamide
CAS:Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
Fórmula:C13H19N3O3Pureza:98.46%Cor e Forma:SolidPeso molecular:265.31Isoliensinine
CAS:Isoliensinine (Isoliensinin) is a natural product, a bisbenzylisoquinoline alkaloid. Isoliensinine has antitumor and antioxidant effects. Cost effective and quality assured.Fórmula:C37H42N2O6Pureza:98.53% - 99.79%Cor e Forma:SolidPeso molecular:610.74Ref: TM-T5S1103
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€1mL*10mM (DMSO)94,00€Pinoresinol
CAS:Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injuryFórmula:C20H22O6Pureza:98.67%Cor e Forma:SolidPeso molecular:358.39Ref: TM-TN2080
1mg54,00€5mg114,00€10mg177,00€25mg295,00€50mg442,00€100mg620,00€1mL*10mM (DMSO)128,00€1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Fórmula:C21H13ClF3N3O2Pureza:99.41%Cor e Forma:SolidPeso molecular:431.8Ref: TM-T22424
1mg42,00€2mg55,00€5mg88,00€10mg127,00€25mg264,00€50mg432,00€100mg622,00€200mg873,00€1mL*10mM (DMSO)99,00€2-Deoxy-D-glucose
CAS:2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.Fórmula:C6H12O5Pureza:98% - ≥98%Cor e Forma:White PowderPeso molecular:164.16BX-912
CAS:BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.Fórmula:C20H23BrN8OPureza:98.29% - 99.34%Cor e Forma:SolidPeso molecular:471.35Ref: TM-T1837
1mg50,00€2mg71,00€5mg85,00€10mg137,00€25mg281,00€50mg470,00€100mg632,00€1mL*10mM (DMSO)88,00€Supinoxin
CAS:Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).Fórmula:C22H24FN5O4Pureza:99.83% - 99.95%Cor e Forma:SolidPeso molecular:441.46Ref: TM-T16961
1mg107,00€5mg222,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€1mL*10mM (DMSO)245,00€CI-1040
CAS:CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).Fórmula:C17H14ClF2IN2O2Pureza:99.64%Cor e Forma:Off-White To Pale Beige SolidPeso molecular:478.66GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64CCT128930 hydrochloride
CAS:CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.Fórmula:C18H21Cl2N5Pureza:98.55%Cor e Forma:SolidPeso molecular:378.3Ref: TM-T6303L
1mg49,00€5mg92,00€10mg148,00€25mg240,00€50mg359,00€100mg523,00€200mg772,00€1mL*10mM (DMSO)104,00€Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Fórmula:C9H18N2O3PtPureza:98.00%Cor e Forma:SolidPeso molecular:397.33L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Fórmula:NAPureza:97%Cor e Forma:SolidPeso molecular:N/ASGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Fórmula:C20H22F3N5OPureza:99.3% - >99.99%Cor e Forma:SolidPeso molecular:405.42Elesclomol
CAS:Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier.Fórmula:C19H20N4O2S2Pureza:97.17% - 99.51%Cor e Forma:SolidPeso molecular:400.52Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Fórmula:C10H19N2O5PPureza:99.99% - ≥95%Cor e Forma:SolidPeso molecular:278.24Ref: TM-T6641
1mg34,00€5mg67,00€10mg93,00€25mg152,00€50mg230,00€100mg363,00€200mg528,00€1mL*10mM (DMSO)67,00€HO-3867
CAS:HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.Fórmula:C28H30F2N2O2Pureza:91.18% - 99.21%Cor e Forma:SolidPeso molecular:464.55LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69kauran-16,17-diol
CAS:Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7Fórmula:C20H34O2Pureza:99.93%Cor e Forma:SolidPeso molecular:306.48Ref: TM-T4951
1mg64,00€5mg170,00€10mg245,00€25mg371,00€50mg504,00€100mg675,00€200mg900,00€1mL*10mM (DMSO)163,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47NSC 95397
CAS:NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).Fórmula:C14H14O4S2Pureza:98.66%Cor e Forma:SolidPeso molecular:310.39Diffractaic Acid
CAS:Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.Fórmula:C20H22O7Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:374.38SKI II
CAS:SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.Fórmula:C15H11ClN2OSPureza:99.34% - 99.93%Cor e Forma:SolidPeso molecular:302.78[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Fórmula:C17H26O4Pureza:98% - 99.66%Cor e Forma:Light Yellow OilinessPeso molecular:294.39STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:98.66%Cor e Forma:SolidPeso molecular:461.53TREM2-IN-1
CAS:TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophagesFórmula:C46H68N2O20PtPureza:98.56%Cor e Forma:SolidPeso molecular:1164.12GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Cor e Forma:SolidPeso molecular:333.36CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Cor e Forma:SolidPeso molecular:551.48
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