Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(127 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DAPK Substrate Peptide acetate
DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.Fórmula:C70H115N25O17Pureza:98.12%Cor e Forma:SolidPeso molecular:1578.82Concanavalin A
CAS:Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.Fórmula:C23H32N6O8SPureza:98%Cor e Forma:SolidPeso molecular:104-112 kDaPHA-665752
CAS:PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Fórmula:C32H34Cl2N4O4SPureza:97.05% - 98.82%Cor e Forma:SolidPeso molecular:641.61Notopterol
CAS:1. Notopterol induces apoptosis and inhibits cell cycle-specific.Fórmula:C21H22O5Pureza:97.57% - 99.96%Cor e Forma:SolidPeso molecular:354.40VR23
CAS:VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.Fórmula:C19H16ClN5O6SPureza:98.99% - 99.22%Cor e Forma:SolidPeso molecular:477.88Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Fórmula:C17H16O4Pureza:99.18% - 99.35%Cor e Forma:Less Transparent Liquid Colorless Transparent LiquidPeso molecular:284.31HBX 41108
CAS:HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.Fórmula:C13H3ClN4OPureza:95.63%Cor e Forma:SolidPeso molecular:266.64CGP 57380
CAS:CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-likeFórmula:C11H9FN6Pureza:98.49%Cor e Forma:SolidPeso molecular:244.23(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Fórmula:C21H28O2Pureza:98.93% - 99.72%Cor e Forma:SolidPeso molecular:312.45NSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Fórmula:C38H40N10Pureza:98.69% - 99.91%Cor e Forma:SolidPeso molecular:636.79Ref: TM-T6909
2mg39,00€5mg58,00€1mL*10mM (DMSO)80,00€10mg90,00€25mg172,00€50mg280,00€100mg405,00€500mg888,00€Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Fórmula:C37H42Cl2N2O6Pureza:95% - 99.99%Cor e Forma:SolidPeso molecular:681.65Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Fórmula:C19H21NO4Pureza:98.62%Cor e Forma:SolidPeso molecular:327.37SP-141
CAS:SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.Fórmula:C22H16N2OPureza:98.01%Cor e Forma:SolidPeso molecular:324.38BIO-acetoxime
CAS:BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.Fórmula:C18H12BrN3O3Pureza:97.15%Cor e Forma:SolidPeso molecular:398.21Ref: TM-T6787
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg177,00€50mg281,00€100mg439,00€5,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Fórmula:C18H16O5Pureza:97.53%Cor e Forma:SolidPeso molecular:312.32Dehydroeffusol
CAS:Dehydroeffusol: anti-cancer, anxiolytic, sedative; halts gastric cancer growth via ER stress and apoptosis.Fórmula:C17H14O2Pureza:99.35%Cor e Forma:SolidPeso molecular:250.29Domatinostat tosylate
CAS:4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).Fórmula:C30H29N5O6S2Pureza:97.35% - >99.99%Cor e Forma:Solid PowderPeso molecular:619.71Spautin-1
CAS:Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Fórmula:C15H11F2N3Pureza:97.69% - 98.99%Cor e Forma:SolidPeso molecular:271.26Ref: TM-T1937
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg63,00€25mg105,00€50mg187,00€100mg281,00€200mg420,00€AKT inhibitor VIII
CAS:AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.Fórmula:C34H29N7OPureza:98.31% - 98.65%Cor e Forma:Pale Yellow SolidPeso molecular:551.64LJH685
CAS:LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).Fórmula:C22H21F2N3OPureza:99.13% - 99.78%Cor e Forma:SolidPeso molecular:381.42Ref: TM-T6877
1mg37,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg127,00€25mg240,00€50mg401,00€100mg603,00€200mg848,00€PF-543 hydrochloride
CAS:PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Fórmula:C27H32ClNO4SPureza:98.9% - 99.93%Cor e Forma:SolidPeso molecular:502.1Sesamol
CAS:Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats.
Fórmula:C7H6O3Pureza:99.67% - 99.76%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:138.12Ginsenoside F5
CAS:Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
Fórmula:C41H70O13Pureza:99.78% - 99.86%Cor e Forma:SolidPeso molecular:770.99Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Fórmula:C51H82O21Pureza:99.51% - 99.63%Cor e Forma:SolidPeso molecular:1031.18Sophoridine
CAS:Sophoridine, a natural Chinese anticancer drug, has a potent derivative 6b targeting DNA topoisomerase I in tumor cells, inducing apoptosis.Fórmula:C15H24N2OPureza:97.33% - 99.28%Cor e Forma:SolidPeso molecular:248.36DBEQ
CAS:DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Fórmula:C22H20N4Pureza:98.93% - ≥95%Cor e Forma:SolidPeso molecular:340.42Ref: TM-T1969
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg85,00€25mg152,00€50mg264,00€100mg334,00€200mg494,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Fórmula:C60H82N8O10Pureza:97.76%Cor e Forma:SolidPeso molecular:1075.36Dipyrithione
CAS:Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activityFórmula:C10H8N2O2S2Pureza:99.9%Cor e Forma:Beige Crystalline PowderPeso molecular:252.31Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Fórmula:C15H12O3Pureza:98.07% - 99.18%Cor e Forma:SolidPeso molecular:240.25Ref: TM-T16522
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg353,00€50mg537,00€100mg767,00€Anisomycin
CAS:Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Fórmula:C14H19NO4Pureza:98.33% - 99.81%Cor e Forma:White Crystalline SolidPeso molecular:265.3ARS-853
CAS:ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFórmula:C22H29ClN4O3Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:432.94Ref: TM-T7414
1mg142,00€1mL*10mM (DMSO)338,00€5mg353,00€10mg525,00€25mg843,00€50mg1.144,00€100mg1.549,00€500mg3.087,00€Lorlatinib
CAS:Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFórmula:C21H19FN6O2Pureza:99.77% - 99.95%Cor e Forma:SolidPeso molecular:406.41Ref: TM-T3061
1mg34,00€2mg42,00€5mg60,00€1mL*10mM (DMSO)66,00€10mg89,00€25mg137,00€50mg212,00€100mg374,00€MFCD01917484
CAS:MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.Fórmula:C14H15NO3SPureza:98.09%Cor e Forma:SolidPeso molecular:277.34Taccalonolide A
CAS:Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it isFórmula:C36H46O14Pureza:98.16% - 99.4%Cor e Forma:SolidPeso molecular:702.74Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Fórmula:C21H27N5O3Pureza:99.14% - 99.93%Cor e Forma:SolidPeso molecular:397.47β-Elemonic Acid
CAS:β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.Fórmula:C30H46O3Pureza:99.61% - 99.8%Cor e Forma:SolidPeso molecular:454.68Ref: TM-T2S0618
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg110,00€25mg192,00€50mg286,00€100mg425,00€200mg612,00€BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Fórmula:C10H9NO2SPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:207.25Ref: TM-T1902
5mg48,00€1mL*10mM (DMSO)50,00€10mg54,00€25mg90,00€50mg161,00€100mg251,00€200mg378,00€500mg627,00€(6R)-FR054
CAS:(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.Fórmula:C14H19NO8Pureza:99.61%Cor e Forma:SolidPeso molecular:329.3(-)-Epipodophyllotoxin
CAS:(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.Fórmula:C22H22O8Pureza:99.72% - 99.97%Cor e Forma:SolidPeso molecular:414.41PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Fórmula:C28H41N7O3Pureza:98.15% - 98.21%Cor e Forma:Yellow SolidPeso molecular:523.67Ref: TM-T2642
5mg40,00€10mg54,00€1mL*10mM (DMSO)56,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Cor e Forma:SolidPeso molecular:394.36Ref: TM-T6126
1mg48,00€1mL*10mM (DMSO)94,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Cor e Forma:SolidPeso molecular:356.22Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Cor e Forma:White Crystalline Granular OdorlessPeso molecular:299.66AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Fórmula:C18H16F2N6Pureza:96.02% - 99.88%Cor e Forma:SolidPeso molecular:354.36AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Fórmula:C27H32N6Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:440.58Ref: TM-T2116
2mg47,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€18α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Fórmula:C30H46O4Pureza:98.54% - 99.68%Cor e Forma:SolidPeso molecular:470.68Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Fórmula:C13H14N2O3Pureza:99.42%Cor e Forma:SolidPeso molecular:246.26Ref: TM-T7131
2mg44,00€5mg67,00€1mL*10mM (DMSO)73,00€10mg103,00€25mg193,00€50mg295,00€100mg425,00€200mg595,00€Valepotriate
CAS:Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.Fórmula:C22H30O8Pureza:97.29% - 99.90%Cor e Forma:SolidPeso molecular:422.47(E)-Flavokawain A
CAS:(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.Fórmula:C18H18O5Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:314.33
