Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Fórmula:C14H14N2O4SPureza:97.67% - >99.99%Cor e Forma:Yellow CrystallinePeso molecular:306.34N-Ethylmaleimide
CAS:<p>N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.</p>Fórmula:C6H7NO2Pureza:99.50%Cor e Forma:White SolidPeso molecular:125.13Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Fórmula:C13H8O4Pureza:99.14% - 99.67%Cor e Forma:SolidPeso molecular:228.2Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Fórmula:C23H19Cl2FN6OPureza:98.80%Cor e Forma:SolidPeso molecular:485.341A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Fórmula:C16H16F3N3Pureza:99.71%Cor e Forma:SolidPeso molecular:307.31KY-05009
CAS:<p>KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).</p>Fórmula:C18H16N4O2SPureza:99.89%Cor e Forma:SolidPeso molecular:352.41Etomoxir sodium salt
CAS:<p>Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis.</p>Fórmula:C15H18ClO4·NaPureza:99.34% - 99.82%Cor e Forma:SolidPeso molecular:320.74Larotrectinib
CAS:<p>Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).</p>Fórmula:C21H22F2N6O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:428.44PRT062607 hydrochloride
CAS:<p>PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.</p>Fórmula:C19H23N9O·HClPureza:97.7% - 99.81%Cor e Forma:SolidPeso molecular:429.91PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Fórmula:C12H12ClN3OPureza:99.56% - 99.92%Cor e Forma:SolidPeso molecular:249.69Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Cor e Forma:SolidPeso molecular:288.43Indinavir sulfate
CAS:<p>Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.</p>Fórmula:C36H49N5O8SPureza:99.75% - >99.99%Cor e Forma:White PowderPeso molecular:711.87Mimosine
CAS:<p>L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.</p>Fórmula:C8H10N2O4Pureza:99.2% - 99.84%Cor e Forma:Crystals From Water SolidPeso molecular:198.18GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13AZD-8055
CAS:<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Fórmula:C25H31N5O4Pureza:98% - 99.69%Cor e Forma:SolidPeso molecular:465.54GSK3326595
CAS:<p>GSK3326595 (EPZ015938) is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).</p>Fórmula:C24H32N6O3Pureza:97.7% - 99.63%Cor e Forma:SolidPeso molecular:452.55MPP dihydrochloride (289726-02-9 Free base)
CAS:<p>MPP dihydrochloride is a highly selective antagonist of estrogen receptor alpha (ERα).</p>Fórmula:C29H33Cl2N3O3Cor e Forma:SolidPeso molecular:542.5Siramesine hydrochloride
CAS:<p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>Fórmula:C30H32ClFN2OPureza:99.72% - >99.99%Cor e Forma:SolidPeso molecular:491.04Piclidenoson
CAS:<p>Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.</p>Fórmula:C18H19IN6O4Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:510.29ASK1-IN-2
CAS:<p>ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.</p>Fórmula:C19H17FN6OPureza:98.79%Cor e Forma:SolidPeso molecular:364.38Oxychlororaphine
CAS:<p>Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.</p>Fórmula:C13H9N3OPureza:98.3%Cor e Forma:Green-Yellow SolidPeso molecular:223.23Pitavastatin sodium
CAS:<p>Pitavastatin sodium inhibits HMG-CoA reductase, enhances LDL-C receptors, and has various protective effects.</p>Fórmula:C25H23FNNaO4Cor e Forma:SolidPeso molecular:443.45L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.11ALSTERPAULLONE
CAS:<p>Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec</p>Fórmula:C16H11N3O3Pureza:99.8%Cor e Forma:SolidPeso molecular:293.28SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Cor e Forma:Orange To Brown PowderPeso molecular:516.54ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Cor e Forma:Pale Yellow SolidPeso molecular:513.59Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Cor e Forma:SolidPeso molecular:320.26Cannabigerol
CAS:<p>Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also</p>Fórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48FX1
CAS:<p>FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).</p>Fórmula:C14H9ClN2O4S2Pureza:97.59%Cor e Forma:SolidPeso molecular:368.82TT-232 TFA(147159-51-1 free base)
CAS:<p>TT2-32 TFA induces a biphasic activation of phosphotyrosine phosphatase activity in human colon tumor cell line, SW620</p>Fórmula:C47H59F3N10O11S2Pureza:99.27% - 99.8%Cor e Forma:SolidPeso molecular:1061.16(Z)-Mirin
CAS:<p>(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.</p>Fórmula:C10H8N2O2SPureza:99.67% - 99.76%Cor e Forma:SolidPeso molecular:220.25INH1
CAS:<p>INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.</p>Fórmula:C18H16N2OSPureza:99.80%Cor e Forma:SolidPeso molecular:308.45-Geranoxy-7-methoxycoumarin
CAS:<p>5-Geranoxy-7-methoxycoumarin shows antifungal activity.</p>Fórmula:C20H24O4Pureza:98.94% - 99.99%Cor e Forma:SolidPeso molecular:328.4CRT0066101 dihydrochloride
CAS:<p>CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).</p>Fórmula:C18H22N6O·2HClPureza:99.85%Cor e Forma:SolidPeso molecular:411.33NSC 23766 trihydrochloride
CAS:<p>NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.</p>Fórmula:C24H35N7·3HClPureza:96.48% - 99.54%Cor e Forma:SolidPeso molecular:530.96Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Fórmula:C10H16O8Pureza:99.2% - >99.99%Cor e Forma:SolidPeso molecular:264.23Thalidomide-O-C6-NH2 hydrochloride
CAS:<p>Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-</p>Fórmula:C19H24ClN3O5Pureza:97.45%Cor e Forma:SolidPeso molecular:409.86Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Cor e Forma:SolidPeso molecular:558.7Pyraclostrobin
CAS:<p>Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.</p>Fórmula:C19H18ClN3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:387.82Azathioprine Sodium
CAS:<p>Azathioprine Sodium is a pro-drug converted to 6-MP, inhibiting DNA/RNA synthesis, curbing cell proliferation, especially in lymphocytes.</p>Fórmula:C9H6N7NaO2SCor e Forma:SolidPeso molecular:299.24Imipramine hydrochloride
CAS:<p>Imipramine HCl: 1st-gen tricyclic antidepressant, inhibits serotonin and norepinephrine uptake, blocks aSMase, reduces MV/exosome secretion.</p>Fórmula:C19H25ClN2Pureza:99.65% - 99.98%Cor e Forma:White To Off-White /Hydrochloride/ Un 1230 3/Pg 2Peso molecular:316.87Scopoletin
CAS:<p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>Fórmula:C10H8O4Pureza:97.06% - 99.88%Cor e Forma:Yellow To Beige Crystalline PowderPeso molecular:192.17Thalidomide-O-amido-C4-NH2 TFA
CAS:<p>Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized E3 ligase ligand-linker conjugate.</p>Fórmula:C21H23F3N4O8Pureza:95%Cor e Forma:SolidPeso molecular:516.42Morroniside
CAS:<p>Morroniside regulates liver inflammation, lipid metabolism, protects against diabetic kidney damage, and guards the brain from ischemic injury.</p>Fórmula:C17H26O11Pureza:99.70% - 99.84%Cor e Forma:SolidPeso molecular:406.38HS-1793
CAS:<p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>Fórmula:C16H12O3Pureza:98.16% - 99.82%Cor e Forma:SolidPeso molecular:252.26Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43Garcinol
CAS:<p>Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).</p>Fórmula:C38H50O6Pureza:98.59%Cor e Forma:SolidPeso molecular:602.8MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Fórmula:C20H19ClFN5OSPureza:99.09% - 99.79%Cor e Forma:SolidPeso molecular:431.91SZL P1-41
CAS:<p>SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.</p>Fórmula:C24H24N2O3SPureza:99.60% - 99.87%Cor e Forma:SolidPeso molecular:420.52
