Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Cor e Forma:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.454-IBP
CAS:<p>4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .</p>Fórmula:C19H21IN2OPureza:98.99%Cor e Forma:SolidPeso molecular:420.29OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Larotrectinib
CAS:<p>Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).</p>Fórmula:C21H22F2N6O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:428.44Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Cor e Forma:SolidPeso molecular:384.27B-AP15
CAS:<p>B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.</p>Fórmula:C22H17N3O6Pureza:91.43% - 98.77%Cor e Forma:SolidPeso molecular:419.39Dubermatinib
CAS:<p>Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.</p>Fórmula:C24H30ClN7O2SPureza:98.65% - 99.58%Cor e Forma:SolidPeso molecular:516.06Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Fórmula:C19H20N4OPureza:98% - 99.91%Cor e Forma:SolidPeso molecular:320.39GW 441756
CAS:<p>GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.</p>Fórmula:C17H13N3OPureza:97.73% - 99.8%Cor e Forma:SolidPeso molecular:275.3Citronellyl acetate
CAS:<p>Citronellyl acetate is a natural product</p>Fórmula:C12H22O2Pureza:98%Cor e Forma:LiquidPeso molecular:198.30R406
CAS:<p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Cor e Forma:SolidPeso molecular:628.63PS 48
CAS:<p>PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).</p>Fórmula:C17H15ClO2Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:286.75R406 free base
CAS:<p>R406 free base (R406 (free base)) is a potent Syk inhibitor.</p>Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Cor e Forma:SolidPeso molecular:470.45Mito-LND
CAS:<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Fórmula:C43H45BrCl2N3OPPureza:97.25% - 98.34%Cor e Forma:SolidPeso molecular:801.62Icaritin
CAS:<p>Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.</p>Fórmula:C21H20O6Pureza:97.69% - 99.76%Cor e Forma:SolidPeso molecular:368.38CP-724714
CAS:<p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>Fórmula:C27H27N5O3Pureza:97.1% - 98.82%Cor e Forma:SolidPeso molecular:469.54ASP3026
CAS:<p>ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.</p>Fórmula:C29H40N8O3SPureza:98.78% - 99.81%Cor e Forma:SolidPeso molecular:580.74CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Cor e Forma:SolidPeso molecular:551.48BTZO-1
CAS:<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Fórmula:C13H8N2OSPureza:99.46%Cor e Forma:SolidPeso molecular:240.28COTI-2
CAS:<p>COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.</p>Fórmula:C19H22N6SPureza:99% - 99.55%Cor e Forma:SolidPeso molecular:366.48CI-1040
CAS:<p>CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).</p>Fórmula:C17H14ClF2IN2O2Pureza:99.64%Cor e Forma:Off-White To Pale Beige SolidPeso molecular:478.66Salidroside
CAS:<p>Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C14H20O7Pureza:97.81%Cor e Forma:Red-Brown Fine PowderPeso molecular:300.3C-DIM12
CAS:<p>C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.</p>Fórmula:C23H17ClN2Pureza:97.72% - ≥95%Cor e Forma:SolidPeso molecular:356.85Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Fórmula:C50H83NO21Pureza:98.42% - 99.94%Cor e Forma:White To Light YellowPeso molecular:1034.19MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Fórmula:C20H37N3O4Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:383.53SJ-172550
CAS:<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Fórmula:C22H21ClN2O5Pureza:99.87%Cor e Forma:SolidPeso molecular:428.87L-685458
CAS:<p>L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.</p>Fórmula:C39H52N4O6Pureza:99.62% - 99.80%Cor e Forma:SolidPeso molecular:672.85Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Fórmula:C23H22N6O2Pureza:97.47% - 99.56%Cor e Forma:SolidPeso molecular:414.46Serdemetan
CAS:<p>Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.</p>Fórmula:C21H20N4Pureza:98% - 99.51%Cor e Forma:SolidPeso molecular:328.41Kahweol
CAS:<p>Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB</p>Fórmula:C20H26O3Pureza:99.26% - 99.86%Cor e Forma:Off-White To Yellow SolidPeso molecular:314.42TC11
CAS:<p>TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis</p>Fórmula:C20H22N2O2Pureza:97.86%Cor e Forma:SolidPeso molecular:322.4Oleic acid
CAS:<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Fórmula:C18H34O2Pureza:97.14% - 99.91%Cor e Forma:Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Peso molecular:282.46BC-1258
CAS:<p>BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.</p>Fórmula:C22H22N4S2Pureza:97.48% - 99.64%Cor e Forma:SolidPeso molecular:406.57RA-9
CAS:<p>RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.</p>Fórmula:C19H15N3O5Pureza:98.15%Cor e Forma:SolidPeso molecular:365.34GSK 872 hydrochloride
CAS:<p>GSK872 HCl（1346546-69-7 free base） (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.</p>Fórmula:C19H18ClN3O2S2Pureza:99%Cor e Forma:SolidPeso molecular:419.94LY2857785
CAS:<p>LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).</p>Fórmula:C26H36N6OPureza:99.68%Cor e Forma:Solid PowderPeso molecular:448.6AVN-944
CAS:<p>AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.</p>Fórmula:C25H27N5O5Pureza:99.07% - ≥95%Cor e Forma:SolidPeso molecular:477.51Pilaralisib analogue
CAS:<p>Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.</p>Fórmula:C21H16N6O2S2Pureza:99.3% - 99.72%Cor e Forma:SolidPeso molecular:448.52Ginkgolide B
CAS:<p>Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.</p>Fórmula:C20H24O10Pureza:98.66% - 99.81%Cor e Forma:White Crystal PowderPeso molecular:424.4Roquinimex
CAS:<p>Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and</p>Fórmula:C18H16N2O3Pureza:97.69%Cor e Forma:SolidPeso molecular:308.33Tripterin
CAS:<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Fórmula:C29H38O4Pureza:98.56% - 99.8%Cor e Forma:Red Crystalline PowderPeso molecular:450.61Toyocamycin
CAS:<p>Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (</p>Fórmula:C12H13N5O4Pureza:98.1% - 98.17%Cor e Forma:SolidPeso molecular:291.26Dp44mT
CAS:<p>Dp44mT, a effective iron chelator, has selective antitumor activity.</p>Fórmula:C14H15N5SPureza:99% - 99.02%Cor e Forma:SolidPeso molecular:285.37Adalimumab
CAS:<p>Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.</p>Pureza:95% - 99.50%Cor e Forma:LiquidPeso molecular:145.4 kDaAT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:381.43trans-Chalcone
CAS:<p>trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as</p>Fórmula:C15H12OPureza:99.89%Cor e Forma:SolidPeso molecular:208.26α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Xevinapant
CAS:<p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>Fórmula:C32H43N5O4Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:561.71PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28
